• Journal of the Earthquake Engineering Society of Korea
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• v.11 no.2 s.54
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• pp.95-104
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• 2007

Three types of high-rise RC building structures having irregularity in the lower two stories were selected as prototypes and were performed nonlinear static analysis by using OpenSees to verify the analysis technique and to investigate the seismic capacity of those buildings. The first one has a symmetrical moment resisting frame (Model 1), the second has an infilled shear wall in the central frame (Model 2), and the third has an infilled shear wall only in one of exterior frames (Model 3). Fiber model, which consists of concrete and reinforcing bar represented from stress-strain relationship, is adapted used for simulate the nonlinearity of members, and MVLEM(Multi vertical linear element model) is used for simulate the behavior of wall. The analytical results are simulate the behavior of piloti stories well, for example, the stiffness and yield farce of piloti stories, the up-lift of wall and the variation of lateral stiffness of column due to the variation of axial forces. Overstrength of Model 2 and Model 3 are about 2 times larger than that of Model 1. The reason of the high oversttrength and ductility of Model 2 and Model 3 is that the conservative design of Model 2 and Model 3, whose beam and column sections are the same as those of Model 1. The ductilities of Model 1 and Model 3 are slightly larger than that of Model 1 and Model 3. Model 1 and Model 3 reached mechanism condition, whereas Model 2 failed to the shear failure of shear wall and the large axial forces in columns due to large overturning moment.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.3
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• pp.27-41
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• 2016

Objectives : The purpose of this research is to understand melanin with both Korean and Western medicine.Methods : We investigated the comprehension of melanin in both western and Korean medicine through literature review and studied relationships between melanin and five viscera(五臟), especially liver(肝), spleen(脾), kidney(腎). We Also studied representative pigmentary disorders(melasma, vitiligo) in western and Korean medicine to figure out how to understand pigmentary disorders in oriental medicine.Results : The results are as follows. 1. Melanin is associate with liver, because free coursing(疎泄) function of liver is the origin of transport melanin to keratinocyte from melanocyte. Also, melanogenesis factors like MITF and CREB are closely associated with liver and pigmentary disorders occur frequently after stress conditions or women. 2. Melanin is absorbed and scattered in keratinocytes by the function of spleen. Pigmentary disorders result from failure of spleen and formation of phlegm-retained fluid(痰飮). 3. Kidney essence(腎精) is the origin of melanin formation. In addition, corticosteroid, the major hormone of melanogenesis is secreted by adrenalin and adrenalin belongs to kidney(腎) in Korean medicine. 4. Melasma is created by disorder of melanin transport and absorbtion, so melasma is associated liver (肝) and spleen(脾). Therefore the treatment for melasma may focus on improvement function of liver and spleen. 5. The destruction of melanocyte or abnormal melanogenesis by disorder of the immune system, metabolic and affective disorders can make vitiligo, so vitiligo is associated with liver and kidney which are major part of melanin formation. Therefore the treatment of vitiligo can focus on improvement function of liver(肝) and kidney(腎).Conclusion : We compared Korean and western medicine to understand melanin. We also interpreted the mechanism of melanin and pigmantary disorders in western medicine and considered the relationship with visceral manifestation theory(臟象論) in traditional Korean medicine. Further studies are needed to apply comprehension of melanin to clinical stage.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3431-3436
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• 2016

Background: Carcinogenesis is a multifaceted intricate cellular mechanism of transformation of the normal functions of a cell into neoplastic alterations. Metastasis may result in failure of conventional treatment and death Hence, research on metastatic suppressors in cancer is a high priority. The metastatic suppressor gene CD82, also known as KAI1, is a member of the transmembrane 4 superfamily which was first identified in carcinoma of prostate. Little work has been done on this gene in breast cancer. Herein, we aimed to determine the gene and protein level expression of CD82/KAI1 in breast cancer and its role as a prognosticator. Materials and Methods: In this study, 83 histologically proven cases of breast cancer and a similar number of controls were included. Patient age ranged from 18-70 years. Quantitative Real Time Polymerase Chain Reaction (q-RT PCR) and immunohistochemistry (IHC) were used to investigate KAI1 expression at gene and protein levels, respectively. Statistical analysis was done to correlate expression of KAI1 and clinicopathological parameters. Results: It was revealed that: (i) KAI1 was remarkably diminished in metastatic vs non metastatic breast cancer both at the gene and the protein levels (P < .05); (ii) KAI1 expression levels were strongly correlated with TNM staging, histological grade and advanced stage (p<0.001) and no association was found with any other studied parameter; (iii) Lastly, a significant correlation was observed between expression of KAI1 and overall median survival of BC patients (P = 0.04). Conclusions: Our results suggest that lack of expression of the KAI1 might indicate a more aggressive form of breast cancer. Loss of KAI1 may be considered a significant prognostic marker in predicting metastatic manifestation. When evaluated along with the clinical and pathological factors, KAI1 expression may be beneficial to tailor aggressive therapeutic strategies for such patients.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.36 no.3
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• pp.226-235
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• 1991

This experiment was carried out to obtain the information on the crossability, germination rate, and pollen viability of the progeny from the cross between hexaploid triticale cv. Sinkihomil and five hexaploid wheat varieties. The results are summarized as follows. Seed set was 28.8 to 41.8% (ave-raged 34.1%) in the cross between triticale and wheat, which resulted in 3.61% in F$_2$(selfed F$_1$), 3.99% in F$_1$/P$_1$ 21. 9% in F$_1$/P$_2$ respectively. However, seed set was extremely low in reciprocal crosses when triticale was used as male. In the backcross, crossability was higher in F$_1$/wheat and triticale/F$_1$ than that in wheat/F$_1$ and F$_1$/triticale, respectively. Germination rate of the crossed seed was 95% in F$_1$ 66.3% in F$_2$ (selfed F$_1$), 62.0% in F$_1$/P$_1$ and 81.0% in F$_1$/P$_2$ from the cross between triticale and wheat, respectively. When triticale cv. Sinkihomil was used as male, seeds were degenerated because of the failure of endorsperm development. This might be caused by AAABBBDDR genome constitution in the cytoplasm from a hexaploid wheat. Pollen fertility of F, plant was averaged 34.1% in the cross between triticale and wheat. Significant positive correlation between the pollen fertility and seed set rate in the cross between triticale and wheat were detected.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.490-497
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• 2020

Asphalt pavement accounts for more than 90% of the total pavement in Korea. Pavement is most widely constructed among construction structures. The heat transfer characteristics (Thermophysical Properties) of the asphalt pavement cause the heat island effect in downtown areas. An increasing asphalt surface temperature is one of the major causes of damage to asphalt pavement. This study examined the heat transfer characteristic factors according to solar energy accumulation in an asphalt mixture. The specimens (WC-2 & PA-13, Recycled aggregate used WC-2) used in the experiment were compacted with a Gyratory Compactor. The thermo-physical properties (thermal conductivity, specific heat capacity, thermal diffusivity, and thermal emissivity) and solar energy accumulation were evaluated. The thermal accumulation and HFM tests revealed a 1.2- to 2.0-fold difference. This indicates that the thermal conductivity of the asphalt mixture pavement changes with the accumulation of solar energy. An analysis of the correlation of thermal conductivity according to the surface temperature of the asphalt mixture showed that WC-2 was logarithmic, and PA-13 was linear. Experiments on the heat transfer characteristics of asphalt pavement that can be used for thermal failure modeling of asphalt were conducted.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.29 no.1
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• pp.9-18
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• 2016

The slender structures such as high rise building or marine riser are highly susceptible to dynamic force exerted by fluid-structure interactions among which vortex-induced vibration(VIV) is the main cause of dynamic unstability of the structural system. If VIV occurs in natural frequency regime of the structure, fatigue failure likely happens by so-called lock-in phenomenon. This study presents the numerical analysis of dynamic behavior of both structure and fluid in the lock-in regimes and investigates the subjacent phenomena to hold the resonance frequency in spite of the change of flow condition. Unsteady and laminar flow was considered for a two-dimensional circular cylinder which was assumed to move freely in 1 degree of freedom in the direction orthogonal to the uniform inflow. Fluid-structure interaction was implemented by solving both unsteady flow and dynamic motion of the structure sequentially in each time step where the fluid domain was remeshed considering the movement of the body. The results show reasonable agreements with previous studies and reveal characteristic features of the lock-in phenomena. Not only the lift force but also drag force are drastically increasing during the lock-in regime, the vertical displacement of the cylinder reaches up to 20% of the diameter of the cylinder. The correlation analysis between lift and vertical displacement clearly show the dramatic change of the phase difference from in-phase to out-of-phase when the cylinder experiences lock-in. From the results, it can be postulated that the change of phase difference and flow condition is responsible for the resonating behavior of the structure during lock-in.

• Journal of Korean Clinical Nursing Research
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• v.26 no.2
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• pp.198-206
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• 2020

Purpose: The rapid response team is a patient safety system that detects symptoms and signs of deteriorating inpatients and provides intervention and treatment. This study analyzed the factors influencing the activation time of the team. Methods: This is a descriptive correlation study that analyzed the electronic medical records of patients activated by the rapid response team. The collection period was from January 2014 to December 2017. We analyzed 278 pieces of data activated by the rapid response team for patients aged 16 years or older at C University S Hospital in Seoul. We employed the SPSS 23.0 program for data analysis. Results: The reasons for activation of the rapid response team were oxygen saturation of less than 90.0%, other causes, and change in consciousness. The most common diagnosis of activated patients was respiratory failure (32.4%). The average activation time was 153.43±286.05 min. The activation time was shortest during convulsions (13.29±7.32 min). For patients with a history of kidney disease (B=0.58, p=.008), in case of surgery (B=0.55, p<.001), if the first symptom is mediated by the physician (B=0.53, p=.007) the active time is often extended. On the other hand, activation time is reduced when consciousness changes (B=-0.51, p=.002), especially when oxygen saturation is below 90.0% (B=-0.64, p<.001). Conclusion: Based on the results of the study, it is expected that patients deteriorating in the general ward would be recognized early, which will help in the effective activation of the rapid response team.

• Journal of Dental Rehabilitation and Applied Science
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• v.32 no.4
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• pp.280-292
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• 2016

Purpose: The purpose of this study was to compare the long-term survival rate and peri-implant marginal bone loss related to multiple risk factors including the clinician's experience. Materials and Methods: Four hundred twenty implants in 146 patients, who had involved a supportive periodontal therapy program every 3 to 6 months and had follow up data for at least 5 years, were selected as the study group. Peri-implant marginal bone loss, data of demographic, implant and surgical characteristics were collected from peri-apical radiographs and chart review. Implant survival was regarded as the remaining with radiographic marginal bone level in excess of 50% of the fixture length for any reason. Results: The cumulative survival rate after 5 years of loading was 94.9%. In binary logistic regression analysis, smoking status (P = 0.033) and presence of spontaneous cover screw exposure (P < 0.001) were significantly related to 5-year survival of implants. In stepwise multiple regression analysis, smoking status (P < 0.001), type of abutment connection (P < 0.001) and implant surface (P = 0.033) were significantly related to peri-implant marginal bone level. And the year of resident was not statistically related to 5-year implant survival in simple logistic regression analysis (P = 0.171). Conclusion: Smoking status, spontaneous cover screw exposure, type of abutment connection and implant surface might influence the implant success. There was no significant correlation between the year of resident and implant failure.

• The KIPS Transactions:PartC
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• v.15C no.4
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• pp.281-288
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• 2008

Recently, the advance of multimedia hardware has fostered the development of wireless multimedia sensor network which is able to ubiquitously obtain multimedia content such as image or audio from the environment. The multimedia data which has several characteristics such as large size and correlation between the data requires reliability in transmission. However, the existing solution which take the focus on the efficiency of network mainly, is not appropriate to transmit the multimedia data. In the paper, we proposes a reliable asynchronous image transfer protocol, RAIT. RAIT applies double sliding window method in node-to-node image tansfer to prevent the packet loss caused by network congestion. The double sliding window consists of one sliding window for the receiving queue, which is used for prevention of packet loss caused by communication failure between nodes and the other sliding window for the sending queue which prevents the packet loss caused by network congestion. the routing node prevents the packet loss and guarantees the fairness between the nodes by scheduling the packets based on the image non-preemptively. The RAIT implements the double sliding window method by cross layer design between RAIT layer, routing layer, and queue layer. The experiment shows that RAIT guarantees the reliability of image transmission compared with the existing protocol.

• Restorative Dentistry and Endodontics
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• v.29 no.6
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• pp.504-514
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• 2004

This study compared the dentin shear bond strengths of currently used dentin bonding agents that were irradiated with an LED (Elipar FreeLight, 3M-ESPE) and a halogen light (VIP, BISCO). The optical characteristics of two light curing units were evaluated. Extracted human third molars were prepared to expose the occlusal dentin and the bonding procedures were performed under the irradiation with each light curing unit. The dentin bonding agents used in this study were Scotchbond Multipurpose (3M ESPE), Single Bond (3M ESPE), One-Step (Bisco), Clearfil SE bond (Kuraray), and Adper Prompt (3M ESPE), The shear test was performed by employing the design of a chisel-on-iris supported with a Teflon wall. The fractured dentin surface was observed with SEM to determine the failure mode. The spectral appearance of the LED light curing unit was different from that of the halogen light curing unit in terms of maximum peak and distribution. The LED LCU (maximum peak in 465 nm) shows a narrower spectral distribution than the halogen LCU (maximum peak in 487 nm). With the exception of the Clearfil SE bond (P < 0.05), each 4 dentin bonding agents showed no significant difference between the halogen light-cured group and the LED light-cured group in the mean shear bond strength (P > 0.05). The results can be explained by the strong correlation between the absorption spectrum of camphoroquinone and the narrow emission spectrum of LED.