• Journal of the Korean Institute of Telematics and Electronics B
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• v.28B no.10
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• pp.807-821
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• 1991

A mulitpath MIN(Multistage Interconnection Network), CSMP(Chained Shuffle Multi-Path) network, is proposed, having fault-tolerance and dynamic reroutability. The number of stages and the number of links between adjacent stagges are the same as in single path MINs, so the overall hardware complexity is considerably reduced in comparison with other multipath MINs. The CSMP networks feature links between switches belonging to the same state, forming loops of switches. The network can tolerate multiple faults, up to (N/4)*(log$_2$N-1), having occured in any stages including the first and the last ones(N:NO. of input). To analyze reliability, terminal reliability (TR) and mean time to failure( MTTE) age given for the networks, and the TR figures are compared to those of other static and dynamic rerouting multipath MINs. Also the MTTE figures are compared. The performance of the proposed network with respect to its bandwidth (BW) and probability of acceptance(PA) is analyzed and is compared to that of other more complex multipath MINs. The cost efficiency analysis of reliability and performance shows that the network is more cost-effective than other previously proposed fault-tolerant multipath MINs.

• Journal of Microbiology and Biotechnology
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• v.21 no.12
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• pp.1345-1351
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• 2011

Vancomycin therapy failure due to the emergence of tolerance in pneumococci is increasing. The molecular mechanism of tolerance is not clear, but lytA and $pep^{27}$ are known to be involved. Our aim was to evaluate the expression of both genes in vancomycin-tolerant Streptococcus pneumoniae (VTSP) strains. Eleven VTSP strains from a total of 309 clinical isolates of S. pneumoniae from 1997 to 2006 were classified according to the criteria of Liu and Tomasz. All VTSP strains were evaluated for susceptibility according to CLSI criteria, serotype by the Quellung test, and clonality by PFGE. The expressions of lytA and $pep^{27}$ were analyzed in different growth phases by RT-PCR with and without vancomycin. Eighty-two percent of VTSP strains showed resistance to penicillin, and 100% were sensitive to vancomycin and cefotaxime. The most frequent serotypes of VTSP strains were 23F (4/11) and 6B (3/11). Clonal relationship was observed in only two strains. No significant changes were observed in $pep^{27}$ expression in the three phases of growth in VTSP strains with and without vancomycin. Interestingly, $pep^{27}$ expression in the stationary phase in the non-tolerant reference strain R6 was significantly higher. However, no significant differences in lytA expression were observed between VTSP and R6 strains during the phases of growth analyzed. The absence of changes in $pep^{27}$ expression in VTSP strains in the stationary phase may be related to their ability to tolerate high antibiotic concentrations, and thus, they survive and remain in the host under the antibiotic selective pressure reflected in therapeutic failure.

• The Transactions of the Korea Information Processing Society
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• v.6 no.8
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• pp.2233-2244
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• 1999

It is essential to guarantee high reliability of embedded real-time systems since the failure of such systems may result in large financial damage or threaten human life. Though many researches have devoted to fault tolerant mechanisms, most of them are object-level fault tolerant mechanisms that can detect errors occurred in a single object and treat the errors in object-level. As embedded real-time systems become more complex and larger, there exist faults that cannot be detected by or tolerated with object-level fault tolerance. Hence, system-level fault tolerance is needed. System-level fault tolerance examines the status of a system whether the system is normal or not by analyzing the status of objects. When an error is detected it should be capable of locating the fault and performing an appropriate recovery and reconfiguration action. In this paper, we propose RobustRTO(Robust Real-Time Object) that provides object-level fault tolerance capability and RMO(Region Monitor real-time Object) that offers system-level fault tolerance capability. Then we show how highly dependable fault tolerant systems can be modeled by RobustRTO and RMO. The model is presented based on real-time objects.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.42 no.3 s.303
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• pp.1-10
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• 2005

This paper proposes a novel fault-tolerant gait planning of a hexapod robot considering kinematic constraints. The failure concerned in this paper is a locked joint failure for which a joint in a leg cannot move and is locked in place. It is shown that the conventional fault-tolerant gait of a hexapod robot for forward walking on even terrain may be fallen into deadlock, depending on the configuration of the failed leg. For coping with such deadlock situation, a novel fault-tolerant gait planning is proposed. It can avoid deadlock by adjusting the position of the foot trajectory, and has the same leg sequence and stride length as those of the conventional fault-tolerant gait. To demonstrate the superiority of the proposed scheme, a case study is presented in which a hexapod robot, having walked over even terrain before a locked joint failure, could avoid deadlock and continue its walking by the proposed fault-tolerant gait planning.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.5699-5703
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• 2013

Objective: To investigate the clinical effects of whole brain radiotherapy concomitant with targeted therapy for brain metastasis in non-small cell lung cancer (NSCLC) patients with chemotherapy failure. Materials and Methods: Of the 157 NSCLC patients with chemotherapy failure followed by brain metastasis admitted in our hospital from January 2009 to August 2012, the combination group (65 cases) were treated with EGFR-TKI combined with whole brain radiotherapy while the radiotherapy group (92 cases) were given whole brain radiotherapy only. Short-term effects were evaluated based on the increased MRI in brain 1 month after whole brain radiotherapy. Intracranial hypertension responses, hematological toxicity reactions and clinical effects of both groups were observed. Results: There were more adverse reactions in the combination group than in radiotherapy group, but no significant differences were observed between the two groups in response rate (RR) and disease control rate (DCR) (P>0.05). Medium progression free survival (PFS), medium overall survival (OS) and 1-year survival rate in combination group were 6.0 months, 10.6 months and 42.3%, while in the radiotherapy group they were 3.4 months, 7.7 months and 28.0%, respectively, which indicated that there were significant differences in PFS and OS between the two groups (P<0.05). Additionally, RPA grading of each factor in the combination group was a risk factor closely related with survival, with medium PFS in EGFR and KRAS mutation patients being 8.2 months and 11.2 months, and OS being 3.6 months and 6.3 months, respectively. Conclusions: Whole brain radiotherapy concomitant with target therapy is favorable for adverse reaction tolerance and clinical effects, being superior in treating brain metastasis in NSCLC patients with chemotherapy failure and thus deserves to be widely applied in the clinic.

• Journal of KIISE:Information Networking
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• v.34 no.2
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• pp.120-133
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• 2007

A multicast tree includes several, possibly a large number of, paths connecting source-receiver pairs, and network failure may disable part of the multicast tree. Reconstruction of the entire multicast tree to recover from a component failure is highly undesirable, because some group members have to suffer service disruptions even though the communication paths to/from them are not affected by the failure. To limit reconfiguration region and to maximize the likelihood of successful reconfiguration, we propose and evaluate a pre-planned reconfiguration policy for QoS multicast sessions. Specifically, we equip a reconfiguration path (RP) with each end-to-end path that connects a source-receiver pair in the multicast tree, and reserve resources in advance along the RPs. Efficient resource-sharing techniques are applied to reduce the amount of resources reserved for RPs but not used in the absence of failures. This way, we prevent uncontrolled competition among different multicast sessions which may simultaneously try to recover from failures. We evaluate the performance of the proposed scheme using simulation on randomly-generated networks. We use the shortest-path routing for QoS multicast sessions, and simulate both source-based and shared multicast trees. The evaluation results indicates that successful pre-planned reconfiguration can be achieved for all group members with reasonable overhead. Our scheme is also shown to adapt well to dynamic changes of group membership.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.7 no.2
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• pp.271-287
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• 2013

We propose a new multipath-based reliable routing protocol on MANETs, Multipath-based Reliable routing protocol with Fast-Recovery of failures (MRFR). For reliable message transmission, MRFR tries to find the most reliable path between a source and a destination considering the end-to-end packet reception reliability of the routes. The established path consists of a primary path that is used to transmit messages, and the secondary paths that are used to recover the path when detecting failures on the primary path. After establishing the path, the source transmits messages through the primary path. If a node detects a link failure during message transmission, it can recover the path locally by switching from the primary to the secondary path. By allowing the intermediate nodes to locally recover the route failure, the proposed protocol can handle the dynamic topological change of the MANETs efficiently. The simulation result using the QualNet simulator shows that the MRFR protocol performs better than other protocols in terms of the end-to-end message delivery ratio and fault-tolerance capability.

• Journal of Mechanical Science and Technology
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• v.16 no.9
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• pp.1093-1101
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• 2002

Continuous fiber ceramic composites (CFCCs) have advantages over monolithic ceramics : Silicon Nitride composites are not well used for application because of their low fracture toughness and fracture strength, but CFCCs exhibit increased toughness for damage tolerance, and relatively high stiffness in spite of low specific weight. Thus it is important to characterize the fracture resistance and properties of new CFCCs materials. Tensile and flexural tests were carried out for mechanical properties and the fracture resistance behavior of a SCS6 fiber reinforced Si$_3$N$_4$ matrix CFCC was evaluated. The results indicated that CFCC composite exhibit a rising R curve behavior in flexural test. The fracture toughness was about 4.8 MPa$.$m$\^$1/2 , which resulted in a higher value of the fracture toughness because of fiber bridging. Mechanical properties as like the elastic modulus, proportional limit and the ultimate strength in a flexural test are greater than those in a tensile test. Also a numerical modeling of failure process was accomplished for a flexural test. This numerical results provided a good simulation of the cumulative fracture process of the fiber and matrix in CFCCs.

• Journal of Korea Multimedia Society
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• v.10 no.7
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• pp.882-892
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• 2007

In this paper, we propose a mechanism for both scheduling the hybrid-task set which consists of periodic and aperiodic tasks and recovering tasks with transient faults on the level of the operating system. Existing embedded operating systems would not provide the scheduling of both periodic and aperiodic tasks. Also because of not supporting the recovery of task failures, they can not prevent system failure from transient task faults. Proposed method, on the level of operating system, is able to not only meet the deadlines of all periodic tasks but also complete the execution of aperiodic tasks. In addition, it is able to prevent the system failure from transient task faults by recovering the task faults.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.53 no.4
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• pp.235-245
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• 2004

In this paper, fault tolerant mechanisms are presented for a servo manipulator system designed to operate in a hot cell. A hot cell is a sealed and shielded room to handle radioactive materials, and it is dangerous for people to work in the hot cell. So, remote operations are necessary to handle the radioactive materials in the hot cell. KAERI has developed a servo manipulator system to perform such remote operations. However, since electric components such as servo motors may fail by radiation, fault tolerant mechanisms have to be considered. For fault tolerance of the servo manipulator system, duplication mechanism increasing the reliability of the transport's driving motors and reconfiguration algorithm accommodating the slave's motor failure have been presented. The reconfiguration algorithm recovering the end effector's motion in spite of one motor's failure is based on control allocation redistributing redundant axes. The constrained optimization method and pseudo inverse method have been adopted for control allocation. Simulation examples and real test results have been presented to verify the Proposed methods.