• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.9 no.3
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• pp.278-284
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• 2016

Software reliability in the software development process is an important issue. In infinite failure NHPP software reliability models, the fault occurrence rates may have constant, monotonic increasing or monotonic decreasing pattern. In this paper, infinite failures NHPP models that the situation was reflected for the fault occurs in the repair time, were presented about comparing property. Commonly, the software model of the infinite failures using the linear hazard rate distribution software reliability based on intercept parameter was used in business economics and actuarial modeling, was presented for comparison problem. The result is that a relatively large intercept parameter was appeared effectively form. The parameters estimation using maximum likelihood estimation was conducted and model selection was performed using the mean square error and the coefficient of determination. The linear hazard rate distribution model is also efficient in terms of reliability because it (the coefficient of determination is 90% or more) in the field of the conventional model can be used as an alternative model could be confirmed. From this paper, the software developers have to consider intercept parameter of life distribution by prior knowledge of the software to identify failure modes which can be able to help.

• Radiation Oncology Journal
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• v.16 no.1
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• pp.51-61
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• 1998

Purpose : Treatment of choice for uterine cervix cancer stage IIB is radiotherapy. We analyzed survivals, Prognostic factors, patterns of failure and complications. Materials and Methods : This is a retrospective analysis of 167 patients with stage IIB carcinoma of uterine cervix treated with curative external pelvic and high dose rate intracavitary radiotherapy at the Department of Therapeutic Radiology, Soonchunhyang University Hospital from August 1985 to August 1994. All the patients followed up from 3 to 141 months(mean 60 months) and age of patients ranged from 31 to 78 years at presentation(mean : 55 years). Results : Overall complete response rate was $84\%$. The response rate for squamous cell carcimoma and adenocarcinoma were $86\%$ and $60\%$, respectively. Overall 5-years survival rate and disease free survival rate was 62 and $59\%$, respectively Mass size and treatment response were significant Prognostic factors for survival Pathologic type and parametrial involvement were marginally significants Prognostic factors. Local failure was 43 cases, distant metastasis was 14 cases and local failure plus distant metastasis was 3 cases, and most of local failures occurred within 24 months, distant metastasis within 12 months after treatment Twenty eight($16.8\%$) patients developed late rectal and urinary complications There were tendency to increasing severity and frequency according to increased fractional dose and total(rectal and bladder) dose. Conclusions : Survival rate was significantly related to tumor size and radiotherapy response. Tumor size should be considered in the clinical s1aging. To increased survival and local control, clinical trials such as decreasing duration of radiotherapy or addition of chemotherapy is needed. To detect early recurrence, regular follow up after RT is important. Because total rectal and bladder dose affected late complications. meticulous vaginal packing is needed to optimize dose of normal tissues and to decrease late complications.

• Journal of Pharmaceutical Investigation
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• v.40 no.spc
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• pp.1-7
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• 2010

Since the introduction of the biopharmaceutics classification system (BCS) in 1995, it has viewed as an effective tool to categorize drugs in terms of prediction for bioavailability (BA) and bioequivalence (BE). The BCS consist of four drug categories: class I (highly soluble and highly permeable), class II (low soluble and highly permeable), class III (highly soluble and low permeable) and class IV (low soluble and low permeable), and almost all drugs belong to one of these categories. Likewise, classifying drugs into four categories according to their solubility and permeability is simple and relatively not controversial, and thus the FDA adopted the BCS as a science-based approach in establishing a series of regulatory guidance for the industry. Actually, many pharmaceutical companies have gained a lot of benefits, which directly connect to cost loss and failure decrease in the early stage of drug development. Recently, instead of solubility, using dissolution characteristics (e.g. intrinsic dissolution rate) have provided an improvement in the classification in correlating more closely with in vivo drug dissolution rather than solubility by itself. Furthermore, a newly modified-version of BCS, biopharmaceutics drug disposition classification system (BDDCS), which classify drugs into four categories according to solubility and metabolism, has been introduced and gained much attention as a new insight in respect with the drug classification. This report gives a brief overview of the BCS and its implication, and also introduces the recent new trend of drug classification.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.47 no.1
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• pp.1-6
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• 2010

The lens distortion in the machine vision system is inevitable phenomenon. Distortion is getting worse, due to the selection of lens in the trend of reducing prices and size of the system. In this trend, the distortion correction becomes more important. But, the traditional correction methods has problems, such as complexity and requiring more operations. Effective distorted digital image correction is the precondition of target detection and recognition based on vision inspection. To overcome the disadvantage of traditional distortion correction algorithms, such as complex modeling, massive computation and marginal information loss, an image distortion correction algorithm based on photogrammetry method is proposed in this paper. In our method, we use the lattice image as the measurement target. Through the experimental results, we could find that we can reduce the processing time by 4ms. And also the inspection failure rate of our method was reduced by 2.3% than human-eyes inspection method.

• Journal of Applied Reliability
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• v.14 no.2
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• pp.129-136
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• 2014

Reliability test is focusing to detect the unexpected reliability failure and solve them for the high quality of products. The test data should be used to assess and project the current level of interesting product reliability and so it is very important to have the accurately assessing methodology with test data. There are two type of trend for test data as constant and changing one during testing and this paper shows the difference in the assessing results of these two cases. There is less information how to define the existence of reliability growth rate changing and calculate the parameters of the reliability growth models to make an accurate assessment with such condition, so i established the process and mathematical model to calculate the parameters at such condition to make reliability growth curve with high Goodness of Fit. I validated the new method with the data made from Monte Carlo Simulation and case from Demko (1993). Even the assessed result with the new methodology may be different with the case by case because of very diversity in test condition and testing product quality, but the process and method founded in this research can be applied to any case using Duane and AMSAA model for their test data assessment. I also present the evaluation method to see the effectiveness with new one which is a conventional knowledge and not popular to use, so it is possible to compare the results with the newly presented and conventional method for better business decision.

• Clinical and Experimental Pediatrics
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• v.60 no.6
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• pp.196-201
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• 2017

Purpose: Myocardial dysfunction and dysrhythmias are inevitable consequences of Duchenne muscular dystrophy. We aimed to evaluate specific trends of electrocardiographic changes that reflect the progress of cardiomyopathy in patients with Duchenne muscular dystrophy. Methods: Fifty electrocardiograms (ECGs) of 30 patients (ages 1 to 27 years) who had not been prescribed medications for heart failure treatment at the time of examination were retrospectively analyzed and compared with 116 ECGs of age-matched healthy 116 controls. Heart rate, leads with fragmented QRS (fQRS), corrected QT, Tpeak-to-Tend, and Tpeak-to-Tend/QT were analyzed. Results: The patients with Duchenne muscular dystrophy failed to show a normal age-related decline in heart rate but showed an increasing trend in the prevalence of fQRS, corrected QT, corrected Tpeakto-Tend, and Tpeak-to-Tend/QT over time. In the ${\leq}10-year-old$ patient group, a significant difference was found only in the prevalence of fQRS between the patients and the controls. The prevalence of fQRS, heart rate, Tpeak-to-Tend/QT, and corrected Tpeak-to-Tend demonstrated significant differences between the patients and the controls in the middle age group (11 to 15 years old). All the indexes were statistically significantly different in the ${\geq}16-year-old$ patient group. Conclusion: The prevalence of lead with fQRS representing regional wall motion abnormalities was higher in the young patients than in the young healthy controls, and this might be one of the first signs of myocardial change in the patients. Markers of depolarization and repolarization abnormalities were gradually prominent in the patients aged >10 years. Further studies are needed to confirm these findings.

• Journal of Chest Surgery
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• v.32 no.5
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• pp.422-427
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• 1999

Background: Tachycardia induced heart failure model would be the model of choice for the dilated cardiomyopathy. This more closely resembles the clinical syndrome and does not require major surgical trauma, myocardial ischemia and pharmacological or toxic depression of cardiac function. When heart failure is progressive, application of new surgical procedures to the faling heart is highly risky. It has been shown that recovery trajectory from heart failure is a new method in decreasing animal mortality. The purpose is to establish the control datas for recovery trajectory in the canine heart failure model. Material and Method: 21 mongrel dogs were studied at 4 stages(baseline, at the heart failure, 4 and 8 weeks after recovery). Heart failure was induced during 4 weeks of continuous rapid pacing using a pacemaker. Eight weeks of trajectory of recovery period was allowed. Indices of left ventricular function and dimension were measured every 2 weeks and the hemodynamics were measured by use of Swan-Ganz catheterization and thermodilution method every 4 weeks. Values were expressed as mean${\pm}$standard deviation. Result: 4(20%) dogs died due to heart failure. Left ventricular end-diastolic volume at the 4 stages were 40.8${\pm}$7.4, 82.1${\pm}$21.1, 59.9${\pm}$7.7 and 46.5${\pm}$6.5ml. Left ventricular end-systolic volume showed the same trend. Ejection fractions were 50.6${\pm}$4.1, 17.5${\pm}$5.8, 36.3${\pm}$7.3, and 41.5${\pm}$2.4%. Blood pressure and heart rate showed no significant changes. Pressures of central vein, right ventricle, pulmonary artery, and pulmonary capillary wedge showed significant increase during the heart failure period, normalizing at the end of recovery period. Stroke volumes were 21.5${\pm}$8.2, 12.3${\pm}$3.5, 17.9${\pm}$4.6, and 15.5${\pm}$3.4ml. Blood norepinephrine level was 133.3${\pm}$60.0pg/dL at the baseline and 479.4${\pm}$327.3pg/dL at the heart failure stage(p=0.008). Conclusion: Development of tachycardia induced heart failure model is of high priority due to ready availability and reasonable amenability to measurements. Recovery trajectory after cessation of tachycardia showed reduction of cardiac dilatation and heart function. Application of new surgical procedures during the recovery period could decrease animal mortality.

• Journal of Arbitration Studies
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• v.17 no.1
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• pp.137-155
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• 2007

Since China joined the WTO, the trade between Korea and China has continued to grow by leaps and bounds, making both nations become mutually important trading partners to each other. The volume of trades with China showed a rapid upward trend with an average annual increase rate of 20% and the resultant dispute is also rising. Thus, this study was aimed to make some suggestions and come up with ways of responding claims by surveying Korean trading firms which have experience in making transactions with China to investigate the current status and the actual condition of their occurrence. As a result of this study, firstly, the main cause of such dispute was shown to be the failure to perform the agreement. Secondly, there were malty verbal agreements and due to a deterioration of trust in Chinese firms, the method of a letter of credit was adopted by many Korean firms. Thirdly, the payment and credit appeared to be most important in transactions with China. A credit inquiry is a must in future transactions with China. Fourthly, the indirect cause of the occurrence of trade claims was the difference in commercial practices and as for the way of settling disputes, the agreement through negotiations between the parties involved was the most. Fifthly, small and medium firms should make more of their credit and English proficiency than large ones do.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.31 no.6 s.261
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• pp.718-724
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• 2007

Some of gas turbine model of 7F-Class has constructed and is operating with units domestically. Non-destructive testing (NDT) is one of the methods being used to inspect damage $1^{st}$ stage bucket and review damage trends. We also analyze damage configuration and microstructure according to material and compare with pape of electric power research institute (EPRI). The damaged mode could be determined by leveraging failure analysis. Especially, configuration uprate of bucket is not only to prevent damage during operation but also avoid domestic manufacturing by the competitors. Modifications were mainly concentrated on surfaces such as cooling hole and bucket tips. Analyzing of bucket damage, the earlier model of 7F-Class used with one cycle with equivalent operation hour (EOH), has various cracking of the bucket surface. Bucket damage of new model is centered on tip area (54%) as analyzed by EPRI research. We conclude that improving bucket configuration would increase repair rate on the bucket tip.

• Journal of Applied Reliability
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• v.15 no.2
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• pp.90-100
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• 2015

Reliability growth rate (or reliability growth curve slope) have the two cases of trend as a constant or changing one during the reliability growth testing. The changing case is very common situation. The reasons of reliability growth rate changing are that the failures to follow the NHPP (None-Homogeneous Poisson Process), and the solutions implemented during test to break out other problems or not to take out all of the root cause permanently. If the changing were big, the "Goodness of Fit (GOF)" of reliability growth curve to test data would be very low and then reduce the accuracy of assessing result with test data. In this research, we are using Duane model and AMSAA model for assessing test data and projecting the reliability level of complex and repairable system as like construction equipment and vehicle. In case of no changing in reliability growth rate, it is reasonable for reliability engineer to implement the original Duane model (1964) and Crow-AMSAA model (1975) for the assessment and projection activity. However, in case of reliability growth rate changing, it is necessary to find the method to increase the "GOF" of reliability growth curves to test data. To increase GOF of reliability growth curves, it is necessary to find the proper parameter calculation method of interesting reliability growth models that are applicable to the situation of reliability growth rate changing. Since the Duane and AMSAA models have a characteristic to get more strong influence from the initial test (or failure) data than the latest one, the both models have a limitation to contain the latest test data information that is more important and better to assess test data in view of accuracy, especially when the reliability growth rate changing. The main objective of this research is to find the parameter calculation method to reflect the latest test data in the case of reliability growth rate changing. According to my experience in vehicle and construction equipment developments over 18 years, over the 90% in the total development cases are with such changing during the developing test. The objective of this research was to develop the newly assessing method and the process for GOF level increasing in case of reliability growth rate changing that would contribute to achieve more accurate assessing and projecting result. We also developed the new evaluation method for GOF that are applicable to the both models as Duane and AMSAA, so it is possible to compare it between models and check the effectiveness of new parameter calculation methods in any interesting situation. These research results can reduce the decision error for development process and business control with the accurately assessing and projecting result.