• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.42 no.3
• /
• pp.204-208
• /
• 2009

The withdrawal time of erythromycin in cultured olive flounder was investigated to ensure the food safety of the fish treated with erythromycin. The oral administration of erythromycin was carried out using the experimental diet containing erythromycin (200 mg/kg) daily dose of 40 mg/kg body weight. The 45 day experimental period was broken into 7 days of habituation, 8 days of medication and 30 days of additional feeding without antibiotics. The erythromycin concentration in the flounder muscle had been increased gradually with medication. After 5 days of medication, the concentration increased to its maximum level of 6.05 mg/kg. After discontinuing the antibiotic, the erythromycin concentration decreased drastically and day 9 was below 0.1 mg/kg. The erythromycin concentration had slowly declined from the 6th to the 20th day after medication and disappeared completely after 25 days. From these results, the time needed to reduce the erythromycin level to the 0.2 mg/kg limit adopted by the ED and Japan was suspected to be 4-6 days. Therefore, a reasonable withdrawal time following ED and Japanese regulatory guidelines for erythromycin in the cultured flounder could be estimated to be 10 days.

• Structural Engineering and Mechanics
• /
• v.58 no.2
• /
• pp.277-300
• /
• 2016

Cold-formed steel (CFS) sections are becoming an increasingly popular solution for constructing floors in residential, healthcare and education buildings. Their reduced weight, however, makes them prone to excessive vibrations, increasing the need for accurate prediction of CFS floor modal properties. By combining experimental modal analysis of a full-scale CFS framed building and its floors and their numerical finite element (FE) modelling this paper demonstrates that the existing methods (based on the best engineering judgement) for predicting CFS floor modal properties are unreliable. They can yield over 40% difference between the predicted and measured natural frequencies for important modes of vibration. This is because the methods were adopted from other floor types (e.g., timber or standard steel-concrete composite floors) and do not take into account specific features of CFS floors. Using the adjusted and then updated FE model, featuring semi-rigid connections led to markedly improved results. The first four measured and calculated CFS floor natural frequencies matched exactly and all relevant modal assurance criterion (MAC) values were above 90%. The introduction of flexible supports and more realistic modelling of the floor boundary conditions, as well as non-structural $fa{\c{c}}ade$ walls, proved to be crucial in the development of the new more successful modelling strategy. The process used to develop 10 identified and experimentally verified FE modelling parameters is based on published information and parameter adjustment resulting from FE model updating. This can be utilised for future design of similar lightweight steel floors in prefabricated buildings when checking their vibration serviceability, likely to be their governing design criterion.

• Proceedings of KOSOMES biannual meeting
• /
• 2004.05b
• /
• pp.121-125
• /
• 2004

Recently, High Tensile Steel is adapt to thin plate on the steel structure and marine structure is used widely, It is possible for buckling happens great. Specially, Initial deflection of ship structure happens in place absence necessarily by heat processing of welding or cutting etc. This Initial Deflection is exerted negative impact when thin plate absence complicated nonlinear behaviour accompanied secondary budding. As a result, must idealize initial deflection that occurrence is possible to endow stability and accuracy in the hull structure or marine structure and reflect in early structure design considering secondary buckling. Longi direction of compressive load interacts and analyzed finite element series analysis that apply various kinds initial deflection shape measured actually on occasion that is arranged simply supported condition in this research. Applied ANSYS (elasto-plasticity large deformation finite element method) to be mediocrity finite element program for analysis method and analysis control used in Newton-Raphson method & Arc-length method.

• Asian-Australasian Journal of Animal Sciences
• /
• v.20 no.5
• /
• pp.638-644
• /
• 2007

Differences of meat qualities between Japanese Black and Holstein have been known in Japan, however, the causative proteins and/or the genetic background have been unclear. The aim of this study was to identify candidate proteins causing differences of the meat qualities between the two breeds. Using technique of two-dimensional gel electrophoresis, protein profiling was compared from samples of the longissimus dorsi muscle and subcutaneous adipose tissue. Five protein spots were observed with different expression levels between breeds. By using LC-MS/MS analysis and Mascot program, three of them were identified as ankyrin repeat protein 2, phosphoylated myosin light chain 2 and mimecan protein. Subsequently, we compared the DNA coding sequences of three proteins between breeds to find any nucleotide substitution. However, there was no notable mutation which could affect pI or molecular mass of the proteins. The identified proteins may be responsible for different characteristics of the meat qualities between Japanese Black and Holstein cattle.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.6
• /
• pp.2307-2312
• /
• 2015

Curcumol is a sesquiterpene originally isolated from curcuma rhizomes, a component of herbal remedies commonly used in oriental medicine. Its beneficial pharmacological activities have attract significant interest recently. In this study, anti-cancer activity of curcumol was examined with both in vitro and in vivo models. It was found that curcumol exhibited time- and concentration-dependent anti-proliferative effects in SPC-A-1 human lung adenocarcinoma cells with cell cycle arrest in the G0/G1 phase while apoptosis-induction was also confirmed with flow cytometry and morphological analyses. Interestingly, curcumol did not display growth inhibition in MRC-5 human embryonic lung fibroblasts, suggesting the anti-proliferative effects of curcumol were specific to cancer cells. Anti-neoplastic effects of curcumol were also confirmed in tumor bearing mice. Curcumol (60 mg/ kg daily) significantly reduced tumor size without causing notable toxicity. In conclusion, curcumol appears a favorable anti-cancer candidate for further development.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.23
• /
• pp.10057-10059
• /
• 2015

Positron emission tomography (PET) as the functional component of current hybrid imaging (like PET/CT or PET/MRI) seems to dominate the horizon of medical imaging in coming decades. $^{18}$Flourodeoxyglucose ($^{18}FDG$) is the most commonly used probe in oncology and also in cardiology and neurology around the globe. However, the major capital cost and exorbitant running expenditure of low to medium energy cyclotrons (about 20 MeV) and radiochemistry units are the seminal reasons of low number of cyclotrons but mushroom growth pattern of PET scanners. This fact and longer half-life of $^{18}F$ (110 minutes) have paved the path of a centralized model in which $^{18}FDG$ is produced by commercial PET radiopharmacies and the finished product (multi-dose vial with tungsten shielding) is dispensed to customers having only PET scanners. This indeed reduced the cost but has limitations of dependence upon timely arrival of daily shipments as delay caused by any reason results in cancellation or rescheduling of the PET procedures. In recent years, industry and academia have taken a step forward by producing low energy, table top cyclotrons with compact and automated radiochemistry units (Lab-on-Chip). This decentralized strategy enables the users to produce on-demand doses of PET probe themselves at reasonably low cost using an automated and user-friendly technology. This technological development would indeed provide a real impetus to the availability of complete set up of PET based molecular imaging at an affordable cost to the developing countries.

• Journal of Korean Library and Information Science Society
• /
• v.33 no.4
• /
• pp.37-59
• /
• 2002

The purpose of this study is to identify useful factors for the curriculum development of the archival program in Korea by analyzing archival graduate programs of the Schools of Library and Information Science in English-speaking Canada. Name and history of the schools, degrees, credits, required and elective courses, practice, research, md faculty of archival prgrams, and the official guidelines of ACA and SAA are compared by analyzing web sites and literature review. It is found that Canadian LIS schools offer independent archival programs with a separate MAS degree or a specialization. University of British Columbia, the first LIS school that has a separate MAS degree program, provides a systematically developed curriculum. It also reveals that Canadian archival programs are based on their own principle·md SAA guidelines because ACA guidelines are out of date. Based upon the analysis of the archival programs in Canada, the current situations of the archival graduate programs in Korea are compared and several suggestions ale made f3r the direction of successful archival education in Korea in the end.

• Journal of Advanced Navigation Technology
• /
• v.5 no.2
• /
• pp.141-148
• /
• 2001

This paper describe the development of narrow-band passband filter with small package and low loss, high selectivity performance. This filter is placed between power amplifier and frequency mixer of IMT-2000 mobile equipment. The elliptic-function narrow-band passband filter is designed with new architecture using the microstrip line. This package is very small by $3.2cm{\times}1.25cm$ and have the 3 % 3 dB bandwidth. Also in the passband the insertion loss is about 2.5 dB and is better than older RF SAW filter(insertion loss: 3.2 dB). In the stop-band it has the two deep notch under the -56 dB.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.46 no.2
• /
• pp.186-194
• /
• 2013

We compiled and analyzed long-term time-series data collected in Korea to evaluate changes in oceanographic conditions and marine ecosystems near Jeju Island ($33^{\circ}00^{\prime}-34^{\circ}00^{\prime}\;N$, $125^{\circ}30^{\prime}-127^{\circ}30^{\prime}\;E$) from 1981 to 2010. Environmental data included depth-specific time series of temperature and salinity that have been measured bimonthly since 1961 in water columns at 175 fixed stations along 22 oceanographic lines in Korean waters by the National Fisheries Research & Development Institute, and time series of estimated volume transport of the Tsushima Warm Current (TWC) and Korea Strait Bottom Cold Water (KSBCW) for the period from 1961 to 2008. We analyzed the species composition in terms of biomass of fish species caught by Korean fishing vessels in the waters near Jeju Island (1981-2010). Data were summarized and related to environmental changes using canonical correspondence analysis (CCA). The CCA detected major shifts in fish community structure between 1982 and 1983 and between 1990 and 1992; the dominant species were a filefish during 1981-1992 and chub mackerel from 1992 to 2007. CCA suggested that water temperature and salinity in the mixed layer and the volume transport of the TWC and the KSBCW were significantly related to the long-term changes in the fish community in the waters off Jeju Island. Fish community shifts seemed to be related to the well-established 1989 regime shift in the North Pacific. Further studies are required to elucidate the mechanisms driving climate change effects on the thermal windows and habitat ranges of commercial species to develop fisheries management plans based on reliable projections of long-term changes in the oceanographic conditions in waters off Jeju Island.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.12
• /
• pp.716-722
• /
• 2016

In the recent rapidly changing IT environment, the amount of smart digital data is growing exponentially. As a result, in many areas, utilizing big data research and development services and related technologies is becoming more popular. In SMART learning, big data is used by students, teachers, parents, etc., from a perspective of the potential for many. In this paper, we describe big data and can utilize it to identify scenarios. Big data, obtained through customized learning services that can take advantage of the scheme, is proposed. To analyze educational big data processing technology for this purpose, we designed a system for big data processing. Education services offer the measures necessary to take advantage of educational big data. These measures were implemented on a test platform that operates in a cloud-based operations section for a pilot training program that can be applied properly. Teachers try using it directly, and in the interest of business and education, a survey was conducted based on enjoyment, the tools, and users' feelings (e.g., tense, worried, confident). We analyzed the results to lay the groundwork for educational use of big data.