• Journal of Microbiology and Biotechnology
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• 제31권12호
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• pp.1643-1655
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• 2021

Recent studies have reported dysbiosis of the microbiome in breast tissue collected from patients with breast cancer and the association between the microbiota and disease progression. However, the role of the microbiota in breast tissue remains unclear, possibly due to the complexity of breast cancer and various factors, including racial and geographical differences, influencing microbiota in breast tissue. Here, to determine the potential role of microbiota in breast tumor tissue, we analyzed 141 tissue samples based on three different tissue types (tumor, adjacent normal, and lymph node tissues) from the same patients with breast cancer in Korea. The microbiota was not simply distinguishable based on tissue types. However, the microbiota could be divided into two cluster types, even within the same tissue type, and the clinicopathologic factors were differently correlated in the two cluster types. Risk of regional recurrence was also significantly different between the microbiota cluster types (p = 0.014). In predicted function analysis, the pentose and glucuronate interconversions were significantly different between the cluster types (q < 0.001), and Enterococcus was the main genus contributing to these differences (q < 0.01). Results showed that the microbiota of breast tissue could interact with the host and influence the risk of regional recurrence. Although further studies would be recommended to validate our results, this study could expand our understanding on the breast tissue microbiota, and the results might be applied to develop novel prediction methods and treatments for patients with breast cancer.

• 경영과학
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• 제22권1호
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• pp.103-125
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• 2005

Korean government is planning to adopt double entry bookkeeping with accrual basis in the government accounting system. This paper attempts to identify influencing attitudes of information producers toward the acceptance of the new service system. Several models are introduced, including Luder's Contingency Model, Cheng's Politico-Economic Model of Accounting Policy Choice, Roger's Diffusion of innovation, and Davis's Technology Acceptance Model(TAM). A set of constructs are developed as fellows : information producers' knowledges, experiences, altitudes toward the reform, characteristics of cash based accounting system and new accrual based system, a chief executive officer's willingness to support, availability of supporting systems, and social Influences from external environment. This study also incudes hey factors used in TAM, such as perceived usefulness and ease of use. Survey responses are gathered from accounting officers in government ministries and agencies as well as from local governments. Regression analysis shows that, for information producers, both 'perceived ease of use' and 'perceived usefulness' of the new system are the best explanatory variable for the dependent variable. It has also found that 'perceived usefulness' is explained best by individual characteristics such as knowledge and experiences, quality of current cash based s1n91e entry bookkeeping system, chief executive's support, Positive supporting systems and social influences. The useful guidelines for implementing double-entry bookkeeping system with accrual basis are also provided.

• 한국콘텐츠학회논문지
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• 제7권10호
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• pp.165-174
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• 2007

경제가 성장함에 따라 문화산업에 대한 수요는 빠르게 증가할 것으로 예상된다. 그러나 문화상품이 공공재적 특성을 가지고 있어 정부가 공급한다는 점에서, 얼마나 수요자의 욕구를 충족시킬지가 의문이다. 따라서 본 논문은 충북에서의 문화수요의 결정요인 분석을 통하여 향후 지방정부가 문화산업을 공급하는데 있어서 준거를 제시하고자 함을 목적으로 한다. 이를 위하여 수요자의 문화산업의 포괄적 만족도 결정요인, 문화산업 유형의 결정요인에서 참여형과 관람형 문화산업 중 어떤 유형을 결정할 것인가, 여가수요에서 재화집약적 여가수요 및 시간집약적 여가수요의 결정요인을 계량경제학적 방법을 이용하여 분석하였다. 그리고 분석결과를 활용하여 향후 지방정부가 최적의 문화상품을 공급하기 위하여 수요자의 필요를 최대한 반영할 수 있는 기준을 제시하였다.

• 정보관리연구
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• 제42권1호
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• pp.199-219
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• 2011

국내 외의 지식관리와 관련한 연구 대부분은 민간기업을 대상으로 이루어졌고, 공공부문 중에서 지방자치단체의 지식관리시스템 효과나 핵심요인에 대한 구체적인 사례연구는 부족한 상황이고, 그 기존 연구도 대부분 지식관리시스템 만족 요인 탐색인데 반해서 본 연구에서는 지식관리시스템의 이용 정도를 높이기 위해서는 어떤 영향 요인이 중요한지를 탐색하는 데 있다. 본 연구에서는 지식관리시스템이 갖고 있는 어떤 요인이 지식관리시스템 이용 유무에 원인이 되는지 고찰하기 위하여 분석모형에 포함된 지식관리시스템 케퍼빌리티의 구성요소와 개인 및 조직 케퍼빌리티의 구성요소 및 인구 통계학적 요인들을 독립변수로 하여 로짓회귀모형으로 분석 검증한다. '지식관리시스템 이용 유무'에 가장 영향을 미치는 변수는 '지식창조', 다음으로 유의한 변수인 '지식인프라', '부서장의 추진 의지' 요인도 유의하게 산출되었다.

• 벤처창업연구
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• 제14권2호
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• pp.191-198
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• 2019

최근 정부의 사회적 경제 활성화 정책으로 인해 다수의 소셜 벤처 창업이 활발하게 이뤄지고 있으며 정부 주도의 자금지원 및 다양한 지원 또한 증가되고 있다. 이에 본 연구는 소셜 벤처 기업의 경제적 성과 및 사회적 성과에 영향을 미치는 요인들을 분석함으로써 증가하고 있는 소셜 벤처기업과 정부 지원정책에 실용적이고 유용한 시사점을 제안하고자 하였다. 좀 더 구체적으로본 연구는 사회적 기업가 정신, 사회적 가치 지향성, 사회적 기업가의 경영 역량 및 조직 문화 등의 요인들이 한국에서의 소셜 벤처 기업의 경제적, 사회적 성과에 어떠한 영향을 미치는지를 185개 기업을 대상으로 실증적으로 분석하였다. 아울러 다양한 정부 지원정책의 조절효과를 분석하였다. 연구 결과 소셜 벤처기업의 혁신성, 진취성, 위험 감수성 및 사회적 가치 지향성이 경제적 성과에는 긍정적인 영향을 미치는 것으로 나타났고, 혁신성, 진취성 및 사회적 가치 지향성은 사회적 성과 또한 향상시킬 수 있는 것으로 나타났다. 또한 사회적 기업가의 경영 역량이 기업의 수익성과 성과에 직접적인 영향을 미치는 반면 조직 문화는 기업의 성과에 다소 미미한 영향을 미치는 것으로 나타났다. 마지막으로 정부의 지원은 사회적 기업가 정신, 경영 역량 및 조직 문화가 회사 성과에 미치는 영향에 조절 효과를 보이는 것으로 나타났으며, 소셜 벤처 기업의 경제적 성과도 사회적 성과에 긍정적인 영향을 미치는 것으로 나타났다. 흥미롭게도 우리의 연구 결과에 따르면 사회적 기업의 경영 역량 강화가 기업의 성과 향상을 위한 정부 지원보다 더욱 효과적 일 수 있다는 것을 시사하고 있다. 이에 소셜 벤처 기업의 효과적인 성과 창출을 위해서는 다양한 정부 지원정책도 중요하지만 사회적 기업가의 내부 경영 역량을 향상시키는 것이 굉장히 중요함을 알 수 있다. 정부의 소셜 벤처 지원에서도 자금 지원뿐만 아니라 개별 기업가의 경영 역량 향상에 많은 정책적 관심이 요구된다 하겠다.

• 경영과학
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• 제32권2호
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• pp.51-68
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• 2015

The objective of this study is to empirically examine the relationship between creativity and performance in 10 government- funded research institutes of industrial science and technology. In order to analyze the relationship, the institutes are categorized into the high performance group and the low performance group based on research paper and patents The study uses discriminant analysis to identify the factors causing the difference between the two groups. The results show that there is no significant difference of individual creativity between the two groups whereas there is significant difference of group creativity and organization creativity. The study suggests that performance of government-funded research institutes depends on group and organizational creativity.

• Environmental Engineering Research
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• 제19권2호
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• pp.131-138
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• 2014

The inconvenient truth of sustainable public squat toilet culture varies among nationalities. This culture may be comfortable to the people of China, yet uncomfortable to the non-Chinese, according to the adequate environmental management in Yanbian Korean Autonomous Prefecture (YKAP), northern China. We conducted a series of field surveys and individual interviews (Chinese n = 1,000 and non-Chinese [foreign visitors] n = 100) on several aspects of the public squat toilet: structural properties, waste disposal methods, important factors, and overall satisfaction level. The significant factors in response to the public squat toilets were cleanliness, odor, toilet paper, temperature, soap, other facilities, and presence of cubicles. These factors should be policy priorities of the local government. In addition, 66.2% of Chinese and 91% of foreign visitors desired type E toilets (two full-high partition walls and a door). The results illustrate the nature of a sustainable and beautiful approach to the culturally and environmentally sound management of various types of public squat toilet in YKAP. The government needs to focus on the future-oriented and excreta treatment management of the sustainable toilet culture for residents and visitors of YKAP.

• 아태비즈니스연구
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• 제13권1호
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• pp.213-230
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• 2022

Purpose - The purpose of this study is to find out any potential factors for explanatory variables when calculating the virtual successful bid rate in case of no collusion. Design/methodology/approach - An empirical analysis was conducted in this study with a regression analysis that included 725 bid samples under the public construction technical type bidding. Findings - The result of the basic analysis showed that there are several factors affecting the successful bid rate. First, collusion variable; second, government variable; third, successful bidder design score variable and the number of bidder variable among bidding features; fourth, turnkey variable based on the alternative method; fifth, civil works variable and plant works variable based on building work; sixth, asset variable and the fourth-quarter performance difference variable. However, the technical proposal method variable among bidding features was found to be statistically insignificant in column(4). Research implications or Originality - The significance of this research is that new variable such as the government variable and the fourth-quarter performance difference variable were added in the regression model, which showed statistically significant research results.

• Asian Journal of Innovation and Policy
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• 제6권3호
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• pp.295-312
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• 2017

The purpose of this case study is to understand the sustainability practices of knowledge transfer process at the Malaysian government-industry-academia consortium. At this stage in the research, the R&D consortium is defined as an established entity by two or more organizations that pool resources and shared decision making for cooperative research and development activities. In attempts to understand the formation, outcomes and sustainability of the sustainable knowledge transfer process, this paper conducted a systematic literature review based on Gough, Oliver and Thomas systematic reviews protocol. From the review, the data were enriched and enhanced with a better understanding of sustainable knowledge transfer process. The systematic review resulted in identifying six factors including internal and external perspectives. However, key sustainability factors are not only directly influencing KTP, and the consortium, but are also mediated by other organisational variables.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2012년도 춘계 학술논문 발표대회
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• pp.129-130
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• 2012

Although the order of Design-Build is being expanded by increasing construction scale and demanding hybrid function, the suitable regulation of the contracts is not settled. Design-Build is way by government because there are big construction of much government leading in contract relation high position occupy. So, case that prebendary's claim institution develops by litigation is very rare. But, recently Design-Build is magnified. So, these dispute factors is becoming visualization gradually. The contract system is needed to be consistent by international standard to deal with the problem. This study suggests the useful solutions in detail concerned with the main factor of change order claim by each Design-Build phases through practical sorting and analysis of the causes of Change Order-Claim.