• 한국임상약학회지
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• 제26권3호
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• pp.207-212
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• 2016

Objective: Prescription rate of dabigatran and rivaroxaban, which are the direct oral anticoagulants (DOAC), has increased. We have analyzed the prescription trend and medication use of dabigatran and rivaroxaban in patients with non-valvular atrial fibrillation (NVAF). Methods: It was retrospectively studied from September 2012 to April 2014 using the electronic medical records and the progress notes. Patients with NVAF (n=424) were evaluated on the medication use, prescribing preferences, adverse drug reactions (ADRs) and the availability of prescription reimbursement of dabigatran (n=210) and rivaroxaban (n=214). Results: Dabigatran was prescribed higher than rivaroxaban (23.3% versus 7.5%, p<0.001) in the neurology department, but rivaroxaban was prescribed higher compared to dabigatran in the cardiology department (87.4% versus 74.3%, p<0.001). Dabigatran was prescribed more than rivaroxaban in high risk patients with CHADS2 score ${\geq}3$ (44.3% versus 31.3%, p=0.006). Dabigatran patients seemed to have more ADRs than patients with rivaroxaban (25.2% versus 11.2%, p<0.001), but no serious thrombotic events and bleeding were found. Only 35.6% (n=151) were eligible for prescription reimbursement by the National Health Insurance (NHI). Bridging therapy (86, 31.5%) and direct-current cardioversion (57, 20.2%) were main reasons of ineligibility for reimbursement. Conclusion: Prescription preferences were present in choosing either dabigatran or rivaroxaban for patients with NVAF. Inpatient protocols and procedures considering patient-factors in NVAF need to be developed.

• Journal of Korea Trade
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• 제25권6호
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• pp.105-125
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• 2021

Purpose - This study analyzes the effects that the response to the technical barriers to trade (TBT), which are used by various countries as means to restrict imports, exerts on exports at a time when protectionism is emerging in the face of a global economic downturn. TBT has been widely used in developed countries for the safety and protection of their people. Recently, the use of TBT as a tool of protectionism has increased considerably in developing countries as well. Therefore, this study analyzes the South Korean SMEs' response and export performance. Design/methodology - To analyze SMEs' response to TBT and their export performance, this study conducted empirical analysis through statistical analysis. To this end, the research established a theory based on previous research and designed its hypothesis and research model. To verify the hypothesis and research model, factor analysis addressing validity and reliability was performed using SPSS 25 and AMOS 26, and the structural equation model was analyzed. Findings - This study found the causal relationship between the independent variable, the mediating variable, and the dependent variable adopted against the theoretical background to have little or no effect, in contrast with previous studies. In a break from previous studies, all hypotheses were rejected for innovation strategic competencies, one of the sub-factors of the independent variable, which is believed to be a result of the lack of practical research related to TBT. Originality/value - Previous studies performed analysis using trade statistics or macro data. A number of such studies analyzed the relationship between technical regulation and trade volume. This study differs from previous studies in some respects, because it analyzed the export performance of companies by establishing a hypothesis and implementing a research model with the factors analyzed in previous studies. In addition, a new attempt has been made by classifying the TBT response factors into technology competencies, human resource competencies, and innovation strategic competencies, and utilizing technology innovation and the export support system as mediating effects.

• 정보교육학회논문지
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• 제26권6호
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• pp.517-532
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• 2022

본 연구는 교육대학원생들을 대상으로 비대면 온라인 수업에 관한 주관적 만족도, 학습지속의향 추천 의향의관계와 이에 영향을 미치는 예측 요인들을 실증적 검증하였다. 이에 서울권에 위치하고 있는 E모 대학교의 교육전문 대학원생을 대상으로(N=417) 설문조사를 실시하였다. 연구 결과 첫째, 교육대학원생의 비대면 수업 학습 만족도에 영향을 미치는 요인은 사회적 현존감, 인지된 유용성, 정보시스템품질로 나타났다. 둘째, 학습지속의향에 영향을 미치는 요인으로는 인지된 유용성과 사회적 현존감으로 나타났고 인지된 유용성의 영향력이 매우 컸다. 그리고 교육대학원 학습자의 주관적인 만족도는 학습지속의향에 유의한 영향을 미치지 않아, 만족스러운 태도를 형성한다고 해서 학습지속의향이란 행동으로까지 연결되지는 않음을 검증하였다. 마지막으로 학습만족도는 타인 추천 의향에 긍정적인 영향을 또한 학습지속의향 역시 타인 추천 의향에 긍정적 영향을 미쳤으나, 주목할 점으로 학습만족도가 타인 추천 의향에 미치는 영향력이 상대적으로 매우 컸다는 점이다. 이는 교육대학원 학습자 개인이 인식하는 비대면 온라인 수업에 대한 주관적 태도인 만족도가 최종적으로 타인에게 교육대학원을 추천하는 중요한 역할을 수행한다고 볼 수 있다. 본 연구는 교육대학원생들의 온라인 수업에 대한 전반적 인식을 살펴보았고, 향후 본 연구의 결과가 실제 반영되어 비대면 온라인 수업 커리큘럼과 콘텐츠 구성의 기초 자료로서 실무적 의의를 지닌다.

• 한국임상약학회지
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• 제24권1호
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• pp.15-25
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• 2014

Background: Elderly patients with gastrointestinal (GI) and cardiovascular (CV) risk factors may be more easily exposed to NSAID-related side effects (SEs). Based on the ACG guideline of year 2009, the aim of the study is to evaluate proper use of NSAIDs and gastroprotective drugs according to the degree of GI and CV risk strengths in the patients. Methods: Retrospectively surveyed 410 elderly patients with NSAIDs for more than 30 days at a general hospital in Korea. GI risk factor includes age, ulcer history, high-dose NSIADs, concurrent aspirin use, steroids or anticoagulants. CV risk factor includes angina, myocardial infarction, cerebral infarction, atrial fibrillation or coronary intervention requiring low-dose aspirin. These factors were classified as high/low cardiovascular groups and high/moderate/low GI groups. Results: There were 14 patients in high CV risk group and high GI risk group. The group was recommended not to use NSAIDs as it is not adequate. There were 101 patients in high CV risk group and moderate GI risk group. This group was recommended to use naproxen and PPI/misoprostol. But all patients except one were not adequate. There were 9 patients in low CV risk group and high GI risk group. This group was recommended to use selective COX-2 inhibitor and PPI/misoprostol. 5 cases were proper while 4 cases did not. There were 285 patients in low CV risk and moderate GI risk group who were recommended to use non selective NSAIDs and PPI/misoprostol or selective COX-2 inhibitor only. 103 patients were proper while 182 patients not adequate. Overall, the SEs were higher in those cases for inadequate use of drugs comparing to the adequate. CV SEs were statistically significant. However, SEs for each risk groups were different. For the case of low CV risk group and high/moderate GI risk group, the inadequate use of drugs makes the SE high and the other groups are not. Also, it was not statistically significant. Conclusions: In elderly patients, the inappropriate use of NSAIDs can increase the risk of the disease. Therefore, GI and CV risk must be considered simultaneously, and the proper use of NSAIDs and gastroprotective drugs for each risk groups should be reconsidered.

• 한국실내디자인학회논문집
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• 제21권4호
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• pp.96-105
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• 2012

The fundamental purpose of this study is whether Show Window Display actually affect on purchase and if it does, how much Show Window Display have influence on the buyer's satisfaction. Show windows are most important at clothing stores. The show open types of domestic clothing stores are usually open-type and semi open-type. Show Window Display types of low and middle prices stores are generally opened, horizontal and storied type and the shape, height, opening type and use of ground floor are different by regional distinct features. Generally Show Window Display are consisted by lights, mannequins and directed props. In buying patterns, an impulse buying has more stronger effect than a scheduled buying, a substituted buying and non-buying. An impulse buying are strongly affected by Design and others are prices. The reason why Show Window Display affecting on purchase is the satisfaction of Design and the strong stimulus to purchase(impulse buying), and then Show window Display used by all components strongly has an effect on it. Factors of purchase desires were Design, price and quality in order and factors of purchase motivations were the motivation of clothing design and the motivation of impulse buying. Thus the effects of Show Window Display and factors of purchase motivations are same. As a result of this study, differentiated Show Window Display methods of clothing stores affect the value of goods, the stimulus of purchase and fostering sales effectiveness. Therefore the instruction of Show Window Display methods are indicated by this study.

• Asia pacific journal of information systems
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• 제28권4호
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• pp.320-349
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• 2018

Purpose: The application of IoT is finding continuous acceptance in our daily lives, particularly, smart speakers are making life easier and convenient for consumers. This research aims to develop and test an integrated model of factors influencing consumer's adoption of voice-enabled IoT devices. Design/methodology/approach: Based on the VAM, an integrated voice-enabled IoT device adoption model is proposed. Gender differences on five constructs relating with perceived value (perceived usefulness, perceived enjoyment, perceived security risk, perceived technicality and perceived cost) was also examined through PLS-MGA technique. The usage experience of consumers was also controlled in the integrated VAM. Findings: Result shows that Perceived-Usefulness, Perceived-Enjoyment and Perceived-Cost have a strong effect on Perceived-Value. However, Perceived-Technicality and Perceived-Security-Risk are non-influential and have no significant effect on PV. Additionally, Perceived-Value and Social-Influence plays a significant role in predicting adoption intention. Gender differences also exist in consumers perception of usefulness, enjoyment and cost. In comparison to the basic value-based adoption model, the integrated model provides more insight on consumers adoption of voice-enabled IoT devices. Originality/value: Using an integrated model, this study is one of the first scholarly attempt at modelling the influential factors for adopting smart speakers i.e., voice-enabled IoT devices, with implications for improved adoption.

• 한국항공운항학회지
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• 제22권3호
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• pp.15-23
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• 2014

There have been CFIT(Controlled Flight Into Terrain) accidents that can be prevented if the crew executed go-around. This study is to analyse the common factors of three typical CFIT accidents of Korea in TEM(threat and error management) frame, and the examples of go-around gate and the countermeasures of eight airlines through the survey facilitating go-around to prevent CFIT. The common factors found in three typical CFIT accidents occurred in Korea or by Korean carriers turned out to be in mountainous terrain, in bad weather while in non-precision approach or circling approach by captain as PF(Pilot Flying) when crew make monitoring errors and communication errors. It also turned out that the crew in all three typical tragic CFIT accidents did not execute go-around in unstabilized approaches. The captains did not respond immediately when first officers advised them to go-around until it is too late. Seven out of eight Airlines answered that they use stabilized approach height as 1,000 feet to be stabilized earlier to have more safety margin by enhancing go-around gate regardless of the weather to prevent CFIT in the survey.

• 대한세포병리학회지
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• 제9권2호
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• pp.161-168
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• 1998

Primary breast lesions diagnosed by fine needle aspiration cytology, confirmed by histologic examination were analyzed by morphometry to evaluate the difference between benign and malignant lesions, and the methods obtaining the sample. four size factors and 5 form factors were evaluated in 22 fibroadenomas and 20 carcinomas by image analyzer(Zeiss Ibas 2000) using the H-E stained slides. Nuclear size was significantly larger in the carcinoma cells than fibroadenoma cells both in the cytology and biopsy specimens, but the form factors were not significantly different. Both fibroadencma and carcinoma cells were significantly larger in cytologic smear than histologic section. The cells in the cytology were more regular and round than those in histology, but not statistically significant. Fibroadenomas having cellular proliferation and atypism exhibited larger size and more irregular nuclei than non-proliferative fibroadenoma, but not statistically significant. Therefore nuclear morphometric analysis can be a helpful method to diagnose the questionable breast lesions and is a method appropriate for use as a quality control procedure in the fine needle aspiration cytology.

• 한국환경복원기술학회지
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• 제19권1호
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• pp.155-170
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• 2016

This study established the definition of invasive disturbance species for a sustainable management and biodiversity, and derived the influence factors caused by the species. To define the species, the paper reviewed similar words such as alien species and invasive species, using standard definitions. Also reviewed the results of recent research on the factors of the species. The paper defined the invasive disturbance species as an species whose establishment and spread threaten ecosystems, habitats or species with economic or environmental harm including native and non-native. Through the reviews, The factors were classified as geographic (altitude, slope, and soil, etc.), climate (temperature, precipitation, climate change, etc.) and, anthropogenic (land use, population, road, and human activity, etc.), and species & vegetation structure (species property, local-species richness, and canopy, etc.). Especially, human activity such as urbanization and highways may be associated with both higher disturbance and higher propagule pressure. In the further study, it is required development of mitigation strategies and vegetation structure model against invasive disturbance species in urban forest based on this study.

• Nutrition Research and Practice
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• 제12권1호
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• pp.78-84
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• 2018

BACKGROUND/OBJECTIVES: Folic acid supplementation before pregnancy is known to reduce the risk of neural tube defects. The purposes of this study were to investigate the awareness, knowledge, and use of folic acid supplements along with their associated factors among non-pregnant Korean women of childbearing age. SUBJECTS/METHODS: From August 2012 to March 2013, 704 women aged 19-45 years completed a self-administered questionnaire regarding their awareness, knowledge, and use of folic acid as well as questions to identify risk of inadequate folate intake. RESULTS: Approximately 67% of women reported that they had heard of folic acid, and 23.7% had knowledge of both the role of folic acid in preventing birth defects and appropriate time for taking folic acid supplements to prevent birth defects. However, only 9.4% of women took folic acid supplements at the time of the survey. Women aged 19-24 years, unmarried women, and women who had never been pregnant were less likely to be aware and knowledgeable of folic acid or take folic acid supplements. In addition, women at high risk of inadequate folate intake were less likely to take folic acid supplements. In a multivariate analysis, women aged 19-24 years, women with a high school diploma or lower education level, and unmarried women were less likely to be aware and have knowledge of folic acid. The percentage of women taking folic acid supplements was significantly higher among knowledgeable women than among unknowledgeable women. CONCLUSIONS: These results support our hypothesis that women with knowledge of folic acid are more likely to take folic acid supplements. Therefore, educational programs or campaigns to improve knowledge regarding the importance of folic acid and to promote consumption of folic acid supplements as well as folate-rich foods are needed to target young, less educated, and unmarried women.