• 한국정보과학회논문지:소프트웨어및응용
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• 제37권2호
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• pp.85-94
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• 2010

본 논문에서는 기존의 연구에서 시도되었던 것과는 달리, 복잡하고 추출하기가 어려운 다양한 형태의 자질 및 단서 정보가 필요 없는 합성곱 구문 트리 커널 기반의 단백질 간 상호작용 추출 기법을 소개한다. 이 기법의 특징은 단백질 이름 쌍을 포함한 상호작용 포함 후보 문장에 대한 구문 트리만을 이용하여 추출을 시도한다는 것이며 부가적인 자질이나 커널 함수가 불필요하다는 장점이 있다. 이를 기반으로 본 논문의 연구 성과는 다음과 같다. 첫째, 단백질 간 상호작용 추출에 있어서 구문 트리 커널을 적용할 경우 불필요한 문맥 정보를 효과적으로 제거하는 구문 트리 가지치기 작업이 필수적임을 기존 연구 결과와의 성능 비교로써 증명한다. 둘째, 동일한 학습 조건에서 구문 트리 커널의 소멸 인자(decay factor)는 평활 인자(smoothing factor)로서 중요한 역할을 하며, 성능 변화의 핵심 요소임을 보인다. 특히 학습 집합의 규모에 따라서 소멸인자가 성능에 미치는 영향력이 상이한 패턴으로 나타남을 제시하였다. 결론적으로 기존의 최신 연구결과로서 주장한 "단일 커널보다 혼합 커널의 성능이 더 뛰어나다"라는 가설이 항상 성립하는 것은 아니라는 것을 합성곱 구문 트리 커널 단독으로 적용하여 높은 성능을 나타냄으로써 보여주었다. 동일한 조건으로 수행한 실험에서 기존의 두 연구 결과에 비해 19.8%, 14%의 성능 개선을 나타내었다.

• East Asian mathematical journal
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• 제34권5호
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• pp.623-632
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• 2018

In [7, 8] they introduced a new finite element method for accurate numerical solutions of Poisson equations with corner singularities. They consider the Poisson equations with homogeneous boundary conditions, compute the finite element solutions using standard FEM and use the extraction formula to compute the stress intensity factor(s), then they posed new PDE with a regular solution by imposing the nonhomogeneous boundary condition using the computed stress intensity factor(s), which converges with optimal speed. From the solution they could get an accurate solution just by adding the singular part. Their algorithm involves an iteration and the iteration number depends on the acuracy of stress intensity factors, which is usually obtained by extraction formula which use the finite element solutions computed by standard Finite Element Method. In this paper we investigate the dependence of the iteration number on the convergence of stress intensity factors and give a way to reduce the iteration number, together with some numerical experiments.

• East Asian mathematical journal
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• 제38권5호
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• pp.603-610
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• 2022

In [6, 7] they introduced a new finite element method for accurate numerical solutions of Poisson equations with corner singularities. They consider the Poisson equations with homogeneous boundary conditions, compute the finite element solutions using standard FEM and use the extraction formula to compute the stress intensity factor(s), then they posed new PDE with a regular solution by imposing the nonhomogeneous boundary condition using the computed stress intensity factor(s), which converges with optimal speed. From the solution they could get an accurate solution just by adding the singular part. They considered a partial differential equation with the input function f ∈ L²(Ω). In this paper we consider a PDE with the input function f ∈ H¹(Ω) and find the corresponding singular and dual singular functions. We also induce the corresponding extraction formula which are the basic element for the approach.

• 생약학회지
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• 제49권1호
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• pp.65-69
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• 2018

Torilin is a major sesquiterpene of Torilis japonica (Umbelliferae) fruits and known to be a melanogenesis inhibitor. Extraction conditions are important factor for the efficient preparation to save cost and time in economic aspects. For this reason, this study was conducted to optimize the extraction condition for maximal yield of torilin. For optimization, extraction factors such as extraction solvent, extraction temperature and sample/solvent ratio were tested and optimized for maximum yield of torilin using response surface methodology with Box-Behnken design (BBD). The optimal condition was obtained as a EtOAc concentration in MeOH of 31.8%, an extraction temperature at $30.3^{\circ}C$ and a sample/solvent ratio, 1000 mg/2 ml. The torilin yield under optimal conditions was found to be 9.9 mg/g dried samples, which were well-matched with the predicted value of 10.4 mg/g dried samples. These results will provide useful information about optimized extraction conditions for the development of torilin as cosmetic therapeutics to reduce skin hyperpigmentation.

• 산업융합연구
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• 제13권2호
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• pp.45-54
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• 2015

This Study aims to analyze the factors for the success of commercialization of the facial extraction and recognition image security information system of the domestic companies in Korea. As the results of the analysis, the internal factors for the success of commercialization of the facial extraction and recognition image security information system of the company were found to include (1) Holding of technology for close range facial recognition, (2) Holding of several facial recognition related patents, (3) Preference for the facial recognition security system over the fingerprint recognition and (4) strong volition of the CEO of the corresponding company. On the other hand, the external environmental factors for the success were found to include (1) Extensiveness of the market, (2) Rapid growth of the global facial recognition market, (3) Increased demand for the image security system, (4) Competition in securing of the engine for facial extraction and recognition and (5) Selection by the government as one of the 100 major strategic products.

• Fisheries and Aquatic Sciences
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• 제25권2호
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• pp.76-89
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• 2022

The Lophius litulon liver was used as raw material for the extraction of fish oil via various extraction methods. The extraction rate by water extraction, potassium hydroxide (KOH) hydrolysis and protease hydrolysis were compared and the results revealed the protease hydrolysis extraction had a higher extraction rate with good protein-lipid separation as observed by optical microscope. Furthermore, subsequent experiments determined neutrase to be the best hydrolytic enzyme in terms of extraction rate and cost. The extraction conditions of neutrase hydrolysis were optimized by single-factor experiment and response surface analysis, and the optimal extraction rate was 58.40 ± 0.25% with the following conditions: enzyme concentration 2,000 IU/g, extraction time 1.0 h, liquid-solid ratio 1.95:1, extraction temperature 40.5℃ and pH 6.5. The fatty acids composition in fish oil from optimized extraction condition was composed of 19.75% saturated fatty acids and 80.25% unsaturated fatty acids. The content of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) were 8.06% and 1.19%, respectively, with the ratio (6.77:1) surpassed to the recommendation in current researches (5:1). The results in this study suggest protease treatment is an efficient method for high-quality fish oil extraction from Lophius litulon liver with a satisfactory ratio of DHA and EPA.

• 공업화학
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• 제29권3호
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• pp.325-329
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• 2018

본 연구에서는 항산화성분함량이 높다고 알려진 안젤리카를 이용하여 폴리페놀을 추출하고 반응표면분석법을 이용하여 추출과정을 최적화하였다. 반응표면분석법의 반응치로는 추출수율과 폴리페놀함량을 설정하였고, 추출공정의 계량인자로는 추출시간, 주정/초순수 부피비, 추출온도를 이용하였다. 추출수율과 폴리페놀함량 모두 계량인자의 주효과도와 교호효과도를 모두 고려하였을 때 가장 큰 영향을 미치는 인자는 추출시간이었다. 또한 반응표면분석 결과 안젤리카의 최적추출조건은 추출시간이 2.8 h, 주정/초순수 부피비 64.0 vol%, 추출온도 $56.6^{\circ}C$로 나타났다. 이 조건의 추출수율은 24.6%, 폴리페놀함량은 8.76 mg GAE/g으로 산출되었다. 추출수율과 폴리페놀함량에 대한 회귀방정식의 결정계수 $R^2$은 각각 81.4%와 75.4%이었으며, 종합 만족도는 D = 0.80, 유의성은 5% 이내의 수준에서 인정되었다.

• Natural Product Sciences
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• 제24권2호
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• pp.103-108
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• 2018

The usage of wild ginseng (Panax ginseng C.A. Meyer) has been limited due to short supply and high price. Therefore, sufficient production as well as efficient extraction of mountain ginseng are required for the development as products. In this study, wild ginseng adventitious root cultures were prepared for efficient production with advantages of fast growth and stable production. Treatment of methyl jasmonate (MJ) to wild ginseng adventitious root cultures increased the extraction yield and antioxidative activity. Further investigation on effect of extraction conditions suggested the importance of ethanol concentration on antioxidative activity and extraction yield of MJ-treated wild ginseng adventitious root cultures. Optimized extraction condition of MJ-treated wild ginseng adventitious root cultures for maximum extraction yield and antioxidative activity was determined using response surface methodology with three-level-three-factor Box-Behnken design (BBD). Extraction of 1 g MJ-treated wild ginseng adventitious root culture with 30 ml of 9% ethanol at $30^{\circ}C$ produced 310.2 mg extract with 71.0% antioxidative activity at $100{\mu}g/ml$. Taken together, MJ-treated wild ginseng adventitious root culture is valuable source for wild ginseng usage and optimized extraction condition can be used for the development of functional products or folk remedies.

• 한국군사과학기술학회지
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• 제11권2호
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• pp.95-100
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• 2008

A fast, simple, inexpensive, and reproducible sample preparation for extraction and analysis of HD in water was studied using single-drop microextraction(SDME) and GC-MS. Operation parameters, such as extraction solvent, extraction time were optimized. The optimized conditions were $1\{mu}L$ trichloroethylene and 10 min extraction time. In these conditions, about 42 times higher enrichment factor(EF) was obtained. The detection limit of HD was $1\{mu}g/L$, and the precision expressed as relative standard deviation was about 9.0%.

• 한국전자거래학회지
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• 제9권3호
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• pp.145-154
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• 2004

객체지향 및 컴포넌트지향 소프트웨어 개발 방법론의 클래스의 도출은 개발하려는 소프트웨어의 전체 품질을 결정하는데 중요한 요소이다. 각 방법론에서는 이 부분에 대해 클래스의 정의와 도출하는 방법을 설명하고 있지만 초보 분석자들이 활용하기는 어려운 점이 많다. 그 중, 개념적 갭(conceptual gap)으로 인한 문제는 클래스 도출에 가장 큰 영향을 미친다. 연구에서는 이런 부분을 보완하기 위한 장치로써 세가지 다이어그램을 제안한다. 요구분석과정의 결과를 도식적으로 정리하여 클래스 도출을 보완하기 위한 도구로 정보다이어그램(Information Diagram), 행위다이어그램(Behavior Diagram) 그리고 관리다이어그램(Management Diagram)이다. 세 다이어그램은 시스템의 관련자(stakeholder)가 시스템에 어떤 서비스를 요구하는가에 대한 관점으로 필요한 정보를 찾고, 그에 포함될 수 있는 세부 행위를 분석하고, 누가 이 서비스에 대한 책임이 있는가의 명세이다. 본 연구에서 제안하는 다이어그램들은 기존의 소프트웨어 개발 방법에서 클래스를 도출하는 과정에 활용할 수 있다.