• BMB Reports
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• 제54권8호
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• pp.425-430
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• 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces coronavirus disease 2019 (COVID-19) and may increase the risk of adverse outcomes in lung cancer patients. In this study, we investigated the expression and function of mucin 1 (MUC1) after SARS-CoV-2 infection in the lung epithelial cancer cell line Calu-3. MUC1 is a major constituent of the mucus layer in the respiratory tract and contributes to pathogen defense. SARS-CoV-2 infection induced MUC1 C-terminal subunit (MUC1-C) expression in a STAT3 activation-dependent manner. Inhibition of MUC1-C signaling increased apoptosis-related protein levels and reduced proliferation-related protein levels; however, SARS-CoV-2 replication was not affected. Together, these results suggest that increased MUC1-C expression in response to SARS-CoV-2 infection may trigger the growth of lung cancer cells, and COVID-19 may be a risk factor for lung cancer patients.

• 문화기술의 융합
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• 제7권4호
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• pp.759-764
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• 2021

전기자동차의 배터리를 스마트그리드의 한 요소로 사용하려는 Vehicle-to-Grid(V2G)기술을 사용하기 위해서는 전기자동차와 V2G 서비스 제공자 사이에 결재정보를 포함한 민감한 개인정보 교환을 위한 신뢰성 높은 통신망이 구성되어야한다. 블록체인은 암호화폐의 거래를 위해 고안된 플랫폼으로 중앙의 관리자나 제 3자의 도움을 받지 않고 동등한 노드들에 의해서만 운영되는 신뢰할 수 있는 분산된 데이터베이스 시스템이다. 본고에서는 블록체인의 구조와 운용방식에 대해 알아보고 V2G 시스템에서 블록체인의 활용에 대해 설명하고 분석하였다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 하계학술대회 논문집 A
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• pp.262-264
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• 2002

This paper shows the design standard of KEPCO on the contamination design for 345 kV and 154 kV transmission tower. Up to now, because the design standard of KEPCO on the insulation design contains 154 kV transmission system only, we had investigated the 343 kV system for the revision of design standard, with respect to the contamination design, we have used the same design philosophy which were adopted to the 765 kV transmission tower. In order to determine the number of insulator discs, we had investigated the withstand voltage of discs according to the level of ESDD(Equivalent Salt Deposit Density) and kinds of disc types. The TOV(Power Frequency Temporary Overvoltage) were estimated by EMTP(Electromagnetic Transient Program) for both 154 kV and 345 kV transmission system. The overvoltage level was appeared 1.35 p.u. between phase to ground for both 154 kV and 345 kV transmission system, but finally this factor was not applied to the design standard considering current design standard and economic point of view. With regard to classification of contamination area of 345 kV transmission system, we added the clean area which was not specified in the current design practise.

• 한국산학기술학회논문지
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• 제12권6호
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• pp.2735-2738
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• 2011

본 실리콘 태양전지 셀을 제작하는데 있어서, 기판 표면에서의 광 흡수를 증가시키기 위한 texturing은 KOH+IPA+DI $H_2O$를 혼합한 에칭용액의 온도를 80도로 유지하면서 1~40분 동안 에칭시간을 각각 다르게 하고 태양전지 시료를 제작하였다. 셀의 특성분석은 SEM과 I-V 특성곡선을 이용하였으며, 실리콘 태양전지 셀의 효율과 texturing에 의한 표면 거칠기 사이의 상관성을 조사한 결과, Texturing이 표면 전체적으로 고르게 이루어진 샘플에서 효율이 높게 나타났다. 에칭이 과도하게 일어난 샘플에서는 효율이 오히려 감소하였다.

• BMB Reports
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• 제33권3호
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• pp.202-207
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• 2000

The depletion of intracellular calcium stores by thapsigargin treatment evoked extracellular calcium-dependent membrane currents in Xenopus laevis oocytes. These currents have been compared to those evoked by microinjection of a calcium influx factor (CIF) purified from Jurkat T lymphocytes. The membrane currents elicited by thapsigargin treatment (peak current, $163{\pm}60$ nA) or CIF injection (peak current, $897{\pm}188$ nA) were both dependent on calcium entry, based on their eradication by the removal of extracellular calcium. The currents were, in both cases, attributed primarily to well-characterized $Ca^{2+}-dependent$ $Cl^-$ currents, based on their similar reversal potentials (-24 mV vs. -28 mV) and their inhibition by niflumic acid (a $Cl^-$ channel blocker). Currents induced by either thapsigargin treatment or CIF injection exhibited an identical pattern of inhibitory sensitivity to a panel of lanthanides, suggesting that thapsigargin treatment or CIF injection evoked $Cl^-$ currents by stimulating calcium influx through pharmacologically identical calcium channels. These results indicate that CIF acts on the same calcium entry pathway activated by the depletion of calcium stores and most lanthanides are novel pharmacological tools for the study of calcium entry in Xenopus oocytes.

• E2M - 전기 전자와 첨단 소재
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• 제8권6호
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• pp.780-786
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• 1995

For the execution of RIETAN program adopting Rietveld Analysis Method, the sample superconductor is made according to the solid state synthesis method at 920.deg. C for 24hrs, and was examined for the optimization of parameters needed to analyze Rietveld method with the input of the measured pattern data after measuring the pattern resulted from the X-ray diffraction. It was proven that the lattice constant of the superconductor which was consisted of Pmmm orthorhombic crystal structure in the analyzed space group correspond to the presented theoretical lattice constant a=3.8887(8).angs., b=3.8238(4).angs., c=11.7079.angs.. Therefore, it was examined and confin-ned that the R factor, which was compensated after analyzing the structure of superconductor resulted from this experimented data with the computer simulation, was refined to $R_{wp}$=8.83[%], $R_{P}$=6.47[%], $R_{I}$=10.08[%], $R_{F}$=7.19[%], $R_{E}$=3.76[%]. On the basis of these experimental data, the significant parameter such as the scale factor(S) and the zero point shift(Z) and FWHM value(U,V,W) were optimized as follows; S=2.0827E-3, Z=0.2146, U=4.2761E-2, V=1.7983E-2, and W=2.6768E-2.2.2.2.2.2.

• Nuclear Engineering and Technology
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• 제53권8호
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• pp.2661-2668
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• 2021

Gamma radiation shielding features for three series of binary alloys identified as (Pb-Sn), (Pb-Zn), and (Zn-Sn) have been investigated. The mass attenuation coefficients (µ/ρ) for the selected alloys were simulated using the MCNP-5 code in the energy range between 0.01 and 15 MeV. Moreover, the (µ/ρ) values were computed using WinXCOM database in the same energy range to validate the simulation results. Results reveal a good agreement between the simulated and computed values. The half value layer (HVL), mean free path (MFP), effective atomic number (Z_eff) and exposure buildup factor (EBF) were evaluated for the selected binary alloys. Results showed that the PS1, PZ1, and ZS2 alloys have the best shielding parameters and better than the commercially standard and available radiation shielding materials. Therefore, the investigated alloys can be used as effective radiation shielding materials against gamma ray with energies between 0.01 and 15 MeV.

• Geomechanics and Engineering
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• 제36권6호
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• pp.631-640
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• 2024

In the traditional slope stability analysis, ignoring the spatial variability of slope soil will lead to inaccurate analysis. In this paper, the K-L series expansion method is adopted to simulate random field of soil strength parameters. Based on Random Limit Equilibrium Method (RLEM), the influence of variation coefficient and fluctuation range on reliability of soil slope supported by micro-pile is investigated. The results show that the fluctuation ranges and the variation coefficients significantly influence the failure probability of soil slope supported by micro-pile. With the increase of fluctuation range of soil strength parameters, the mean safety factor of the slope increases slightly. The failure probability of the soil slope increases with the increase of fluctuation range when the mean safety factor of the slope is greater than 1. The failure probability of the slope increases by nearly 8.5% when the fluctuation range is increased from δ_v=2 m to δ_v =8 m. With the increase of the variation coefficient of soil strength parameters, the mean safety factor of the slope decreases slightly, and the probability of failure of soil slope increases accordingly. The failure probability of the slope increases by nearly 31% when the variation coefficient increases from COV_c=0.2, COV_φ=0.05 to COV_c=0.5, COV_φ=0.2.

• 한국동물학회:학술대회논문집
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• 한국동물학회 2000년도 한국생물과학협회 학술발표대회
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• pp.264.3-265
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• 2000

No Abstract, See Full Text

• 한국결정성장학회지
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• 제14권4호
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• pp.129-134
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• 2004

본 연구에서는 기계적 합금화(MA)에 의한 고상-기상반응에 있어서 질소원자가 V-Fe계 합금의 비정질화에 미치는 영향을 조사하였다. 유성형 볼밀을 사용하여 $V_{70}Fe_{30}$혼합분말을 질소가스 분위기 중 MA 처리하였다. 그 결과 160시간 MA 처리에 의하여 비정질상이 생성됨을 알 수 있었다. 160시간 동안 MA 처리한 ($V_{70}Fe$_{30}$)_{0.89}N_{0.11}$ 분말시료의 열분석 결과 약 $600^{\circ}C$에 비정질상의 결정화에 의한 발열 peak가 관찰되었다. 또한 bcc 결정에서 비정질상으로의 구조변화 과정을 X선 및 중성자 회절법을 통하여 조사하였으며, 특히 중성자회절에서는 V원자의 중성자에 대한 간섭성 핵산란진폭이 매우 작은 특징을 이용하였다. 그 결과, 이 합금계에서의 비정질화는 모든 결정구조에서 전형적으로 존재하는 8면체 unit가 우선적으로 붕괴되어 4면체 unit로 변환되어 가는 과정임을 알 수 있었다. 또한 중성자 회절에 의한 구조해석 결과 질소원자는 V원자로 이루어진 다면체의 중심에 위치하고 있음을 알 수 있었다.