• 실천공학교육논문지
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• 제15권2호
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• pp.449-457
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• 2023

본 서술적 조사연구의 목적은 대학생의 호흡기감염 예방행위에 영향을 미치는 요인으로 건강신념과 호흡기 감염관리 자기효능감을 알아보고자 시도되었다. 대상자는 경상북도 K 시 일개 대학에 재학 중인 학생 178명으로 2020년 9월 1일부터 10월16일까지 구조화된 설문지로 자료를 수집하였다. 연구결과는 다음과 같다; 건강신념은 참여자의 성별(t=-2.86, p=.005), 전공계열(F=2.95, p=.034), 처방된 약물 복용 유무(t=2.18, p=.030)와 유의한 차이가 있었다. 호흡기 감염관리에 대한 자기효능감은 대학생의 성별(t=-3.56, p=<.001), 전공계열(F=4.59, p=.004)과 유의한 차이가 있었다. 건강신념(r=.276, p<.001)과 호흡기 감염관리에 대한 자기효능감(r=.195, p<.001)은 호흡기감염 예방행위에 정적 상관이 있었다. 다중회귀분석 결과 호흡기 감염관리에 대한 자기효능감(β=.66, p<.001)이 호흡기감염 예방 행동에 유의한 영향을 미치는 것으로 나타났고, 모형의 설명력은 43%로 나타났다. 따라서, 대학생의 호흡기감염을 예방하기 위한 행동을 촉진하기 위해서는 호흡기 감염관리에 대한 자기효능감을 강화할 수 있는 프로그램이 개발되어야 할 것이다.

• 치위생과학회지
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• 제23권4호
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• pp.320-329
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• 2023

Background: Oral frailty has garnered considerable interest following its identification as a risk factor for physical frailty. The Korean oral frailty diagnosis criteria have emphasized the need for extensive research on oral frailty diagnostic items and interventions. Our study performed an in-depth analysis of the tongue-palate pressure patterns in healthy community-dwelling older adults. Methods: Of the 217 older adults aged ≥60 years who visited a senior center in Wonju, 205 participants who completed tongue pressure measurement were included in the final analysis. Pressure changes over time were recorded by instructing the participants to press their tongue against the hard palate with for 7 seconds per cycle. The participants were divided into the normal and abnormal tongue pressure (NTP and ATP, respectively) groups based on whether they achieved the target tongue pressure at least once; tongue pressure patterns were compared between the groups. Furthermore, the average time taken to achieve the standard tongue pressure value was calculated for the participants in the NTP group and used to evaluate the decrease in tongue pressure in the ATP group. Results: Among the 205 participants, 40.5% had ATP. The tongue pressure graph revealed a gentle and consistent incline that was maintained even after achieving standard tongue pressure in the NTP group. The graph was more extreme in the ATP group, and the changes in the pressure type varied across individuals; the tongue pressure was only 48.4%, 40.7%, 31.9%, and 22.6% of the NTP in the participants in their 60s, 70s, 80s, and ≥90s, respectively (p<0.05). Conclusion: Tongue pressure weakness was observed in 40.5% of the healthy community-dwelling older adults. Furthermore, ATP graphs were observed in the patients with tongue pressure weakness. Thus, activities improving the oral function in community-dwelling older adults and systematic oral rehabilitation programs should be devised to promote normal swallowing.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2021년도 춘계학술대회
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• pp.15-15
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• 2021

Seed coat color and seed weight are among the key agronomical traits that determine the nutritional quality of soybean seeds. This study aimed to evaluate the contents of total protein, total oil and five prominent fatty acids in seeds of 49 soybean varieties recently cultivated in Korea, and assess the influences of seed coat color and seed weight on each. Total protein and total oil contents were in the ranges of 36.28-44.19% and 13.45-19.20%, respectively. Likewise, individual fatty acid contents were in the ranges of 9.90-12.55, 2.45-4.00, 14.97-38.74, 43.22-60.26, and 5.37-12.33% for palmitic, stearic, oleic, linoleic, and linolenic acids, respectively. Our results found significant variations of protein, oil and fatty acid contents between the soybean varieties. Moreover, both seed coat color and seed weight significantly affected total oil and fatty acid contents. Total protein content, however, was not significantly affected by any factor. Among colored soybeans, pale-yellow soybeans were characterized by a high level of oleic acid (30.70%) and low levels of stearic (2.72%), linoleic (49.30%) and linolenic (6.44%) acids, each being significantly different from the rest of colored soybeans (p < 0.05). On the other hand, small soybeans were characterized by high levels of all individual fatty acids except oleic acid. The level of oleic acid was significantly high in large seeds. Cluster analysis grouped the soybeans into two classes with notable content differences. Principal component analysis also revealed fatty acids as the prime factors for the variability observed among the soybean varieties. As expected, total oil and total protein contents showed a negative association with each other (r = -0.714, p < 0.0001). Besides, oleic acid and linoleic acid showed a tradeoff relationship (r = -0.936, p < 0.0001) which was reflected with respect to both seed coat color and seed weight. In general, the results of this study shade light on the significance of seed coat color and seed weight to distinguish soybeans in terms of protein, oil and fatty acid contents. Moreover, the soybean varieties with distinct characteristics and nutritional contents identified in this study could be important genetic resources for consumption and cultivar development.

• 지질공학
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• 제33권4호
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• pp.673-687
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• 2023

데이터 탐색은 수집한 데이터를 다양한 각도에서 관찰 및 이해하는 과정으로 데이터 구조 및 특성 분석을 통해 데이터의 분포와 상관관계를 파악하는 과정이다. 일반적으로 산사태는 다양한 인자들에 의해 유발되고 발생 지역에 따라 유발 인자들이 미치는 영향이 상이하기 때문에 산사태 취약성 분석 이전에 데이터 탐색을 통해 유발 인자 사이의 상관관계를 파악하고 특징적인 유발 인자를 선별한다면 효과적인 분석을 수행할 수 있다. 따라서 본 연구는 데이터 탐색이 예측 모델의 성능에 미치는 결과를 확인하기 위해 두 단계에 걸친 데이터 탐색을 수행하여 인자를 선별하고, 선별된 유발 인자들 사이의 조합과 23개의 전체 유발 인자 조합을 활용하여 딥러닝 기반의 산사태 취약성 분석을 진행하였다. 데이터 탐색 과정에서는 Pearson 상관계수 heat map과 random forest의 인자 중요도 histogram을 활용하였으며, 딥러닝 기반 산사태 취약성 분석 결과의 정확도는 분석을 통해 획득한 산사태 취약 지수 값을 이용해 제작한 산사태 취약성 지도를 confusion matrix 기반의 정확도 검증 방법을 통해 분석하였다. 분석 결과, 전체 23개의 인자를 사용한 산사태 취약성 해석 결과는 55.90%의 낮은 정확도를 보였지만 한 단계의 탐색을 거쳐 선별한 13개 인자를 활용한 취약성 해석 결과는 81.25%의 분석 정확도를 보였고, 두 단계 데이터 탐색을 모두 수행하여 선별된 9개의 유발 인자를 활용한 산사태 취약성 분석 결과는 92.80%로 가장 높은 정확도를 보였다. 따라서 데이터 탐색을 통해 특징적인 유발 인자를 선별하고 분석에 활용하는 것이 산사태 취약성 분석에서 더 좋은 분석 성능을 기대할 수 있음을 확인하였다.

• 대한수의학회지
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• 제63권3호
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• pp.27.1-27.9
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• 2023

Lespedeza cuneata (LC) is a perennial plant used in herbal medicine to treat numerous diseases, including prostatic hyperplasia, diabetes, early atherosclerosis, and hematuria. Reference collections of bioactive compounds of LC are crucial for the determination of their pharmacological properties. However, little is known regarding its anti-oxidative and anti-inflammatory effects in alveolar macrophage (MH-S) cells. This study examined whether LC can inhibit reactive oxygen species and Coal fly ash (CFA) induced inflammation in MH-S cells. The anti-oxidative effects of LC were evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays, anti-inflammatory effects were examined using nitric oxide (NO) assay, and cytotoxicity was analyzed using methyl thiazolyl tetrazolium assay. The expression of inflammatory cytokine genes was assessed through a reverse-transcription polymerase chain reaction. Our results revealed that LC exhibited high radical scavenging activity and a dose-dependent (7.8-1,000 ㎍/mL) inhibition of oxidation as compared to ascorbic acid and Trolox. It also inhibited CFA-induced NO production in MH-S cells. Moreover, it suppressed the CFA exposure-mediated expression of pro-inflammatory mediators and cytokines, including inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), interleukin (IL)-1β, IL-6, and tumor necrosis factor-α. These results suggest that LC is a potent antioxidant and anti-inflammatory agent that can be useful as a nutraceutical product.

• Korean Chemical Engineering Research
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• 제62권2호
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• pp.163-172
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• 2024

본 연구에서는 이산화탄소를 배출하지 않고 수소를 운반할 수 있는 그린 암모니아 공정의 효율적인 설계를 위해 암모니아 액화 시나리오를 다르게 설계하고 이에 대한 경제성 및 환경 영향도 평가를 수행하였다. 순도 99.9 mol%의 148 kmol/hr 액화 암모니아를 생산물로 얻는 것을 목표로 설정하였고 후처리 단계에서 냉각단계 전 기-액분리를 통해 일정량의 액화 암모니아를 분리하고 고압에서 냉각하는 고압 냉각 공정과 기-액분리 과정 없이 바로 감압 후 냉각하여 기-액분리를 시켜 최종생산물을 얻는 저압 냉각 공정의 두 가지 케이스를 설정했다. 이에 대한 타당성 평가를 위해 Aspen Plus를 활용한 시뮬레이션을 수행하였다. 고압 냉각 공정은 많은 기-액분리 공정과 열교환기를 사용하여 초기장치 비용이 부담되지만 상대적으로 총 유틸리티 비용이 91.03 $/hr, duty가 2.81 Gcal/hr 낮아 유지비용이 적게 든다. 저압 냉각 공정은 초기 장치 비용이 낮고 운전이 용이하지만 급격한 압력 강하로 운전이 불안정한 것을 확인 하였다. 환경 영향도 평가 결과 고압 냉각 공정이 저압 냉각 공정보다 전력 사용량을 기준으로 산출한 이산화탄소 환산톤 배출 계수가 0.83 tCO₂eq 더 낮아 환경친화적 임을 확인할 수 있었다. 본 연구 결과를 통해 향후 그린 암모니아 합성 공정에서 여러 상황에 적절한 설계안을 도출할 수 있는 데이터베이스를 확보할 수 있다.

• 한국과학교육학회지
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• 제26권2호
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• pp.222-231
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• 2006

과학경연에서 나타나는 학생들의 내적 참여도와 내적 참여도에 영향을 주는 참여 동기와의 인과관계를 알아보고자 하였다. 탐색적 요인분석을 통하여 내적 참여도를 구성하는 요인으로 흥미와 몰두를 참여 동기를 구성하는 요인으로 사회적 동기, 보상 동기, 선호 동기를 설정하였다. 내적 참여도에 대한 학생들의 응답을 성, 학교유형, 학년에 따른 차이를 변량분석으로 비교한 결과 남학생이 흥미와 몰두에 있어서 여학생보다 유의미하게 높게 인식하였으며 초등학생들이 중학생들에 비해 모든 요인에 대해 높게 인식하였다(p<0.01). 초등학생의 경우 흥미에 있어서는 학년별 차이가 없었으나 몰두에 있어서는 초등학교 4학년 학생들이 유의미하게 낮았다(p<0.01). 중학생의 경우 중학교 3학년 학생들이 흥미와 몰두에 있어서 중학교 1,2 학년 학생들에 비해 유의미하게 낮았다(p<0.01). 과학경연에 대한 내적 참여도와 내적 참여도에 영향을 주는 요인간의 인과관계를 알아보기 위해 경로분석을 실시한 결과, 사회적 동기, 보상동기, 선호 동기가 모두 상관을 가지고 있으며 보상 동기는 몰두에 직접영향을 주며 선호 동기는 흥미에 직접영향올 주고 몰두에는 흥미를 통해서 간접영향을 주며, 흥미는 몰두에 직접영향을 주는 모형이 채택되었다. 내적 참여도의 흥미를 선호 동기만이 변량의 56%을 설명하였으며 몰두는 보상동기와 선호 동기가 변량의 58%를 설명할 수 있었다. 보상 동기는 몰두에 0.17의 직접효과를 주었으며 선호 동기는 흥미에 0.75의 높은 직접효과와 0.27의 몰두에 대한 간접효과를 주었다. 사회적 동기는 내적 참여도에 직접 및 간접효과를 주지 않았으며 흥미는 몰두에 0.49의 직접효과를 주었다.

• 한방재활의학과학회지
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• 제34권2호
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• pp.165-172
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• 2024

Objectives This study aims to report current status and strategies of thread embedding acupuncture (TEA) on face through survey of Korean medicine doctors. Methods The survey was conducted online via e-mail to certified Korean medicine doctors. The questionnaire is developed by Korean medicine doctors in Kyung-Hee Korean Medicine Hospital at Gangdong. The survey mainly consisted with multiple-choice questions on the current status, cost, and adverse reactions. Results TEA was predominantly utilized for cosmetic purposes, and the billing cost was commonly determined based on the number of threads used. The reported incidence of adverse reactions during TEA was 69.9%. The most frequent self-resolving adverse reaction was bruising, while the most common adverse reaction requiring medical intervention or resulting in sequelae was the 'dimple phenomenon'. According to the questionnaire, the primary factor associated with adverse reactions was the treatment area. Conclusions This study provided insights into the practical use of TEA on face in Korean medical clinic.

• Korean Journal of Radiology
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• 제24권4호
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• pp.338-348
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• 2023

Objective: Patients with a history of ischemic stroke are at risk for a second ischemic stroke. This study aimed to investigate the relationship between carotid plaque enhancement on perfluorobutane microbubble contrast-enhanced ultrasonography (CEUS) and future recurrent stroke, and to determine whether plaque enhancement can contribute to risk assessment for recurrent stroke compared with the Essen Stroke Risk Score (ESRS). Materials and Methods: This prospective study screened 151 patients with recent ischemic stroke and carotid atherosclerotic plaques at our hospital between August 2020 and December 2020. A total of 149 eligible patients underwent carotid CEUS, and 130 patients who were followed up for 15-27 months or until stroke recurrence were analyzed. Plaque enhancement on CEUS was investigated as a possible risk factor for stroke recurrence and as a possible adjunct to ESRS. Results: During follow-up, 25 patients (19.2%) experienced recurrent stroke. Patients with plaque enhancement on CEUS had an increased risk of stroke recurrence events (22/73, 30.1%) compared to those without plaque enhancement (3/57, 5.3%), with an adjusted hazard ratio (HR) of 38.264 (95% confidence interval [CI]:14.975-97.767; P < 0.001) according to a multivariable Cox proportional hazards model analysis, indicating that the presence of carotid plaque enhancement was a significant independent predictor of recurrent stroke. When plaque enhancement was added to the ESRS, the HR for stroke recurrence in the high-risk group compared to that in the low-risk group (2.188; 95% CI, 0.025-3.388) was greater than that of the ESRS alone (1.706; 95% CI, 0.810-9.014). A net of 32.0% of the recurrence group was reclassified upward appropriately by the addition of plaque enhancement to the ESRS. Conclusion: Carotid plaque enhancement was a significant and independent predictor of stroke recurrence in patients with ischemic stroke. Furthermore, the addition of plaque enhancement improved the risk stratification capability of the ESRS.

• Korean Journal of Radiology
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• 제24권5호
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• pp.424-433
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• 2023

Objective: To assess the safety and efficacy of balloon dilatation under dual guidance using fluoroscopy and bronchoscopy for treating bronchial stenosis following lung transplantation (LT), and to elucidate the factors associated with patency after the procedure. Materials and Methods: From September, 2012, to April, 2021, 50 patients (mean age ± standard deviation, 54.4 ± 12.2 years) with bronchial stenosis among 361 recipients of LT were retrospectively analyzed. The safety of balloon dilatation was assessed by evaluating procedure-related complications. Efficacy was assessed by evaluating the technical success, primary patency, and secondary patency. Primary and secondary cumulative patency rates were calculated using the Kaplan-Meier method. The factors associated with patency after the procedure were evaluated using multivariable Cox hazard proportional regression analysis. Results: In total, 65 bronchi were treated with balloon dilatation in 50 patients. The total number of treatment sessions was 277 and the technical success rate was 99.3% (275/277 sessions). No major procedure-related complications were noted. During the mean follow-up period of 34.6 ± 30.8 months, primary patency was achieved in 12 of 65 bronchi (18.5%). However, the patency rate improved to 76.9% (50 of 65 bronchi) after repeated balloon dilatation (secondary patency). The 6-month, 1-year, 3-year, and 5-year secondary patency rates were 95.4%, 90.8%, 83.1%, and 78.5%, respectively. The presence of clinical symptoms was a significant prognostic factor associated with reduced primary patency (adjusted hazard ratio [HR], 0.465; 95% confidence interval [CI], 0.220-0.987). Early-stage treatment ≤ 6 months (adjusted HR, 3.588; 95% CI, 1.093-11.780) and prolonged balloon dilatation > 5 min (adjusted HR, 3.285; 95% CI, 1.018-10.598) were associated with significantly higher secondary patency. Conclusion: Repeated balloon dilatation was determined to be safe and effective for treating bronchial stenosis following LT. Early-stage treatment and prolonged balloon dilatation could significantly promote long-term patency.