• Title/Summary/Keyword: Facilitated diffusion

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Facilitated Protein-DNA Binding: Theory and Monte Carlo Simulation

  • Park, Ki-Hyun;Kim, Tae-Jun;Kim, Hyo-Joon
    • Bulletin of the Korean Chemical Society
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    • v.33 no.3
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    • pp.971-974
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    • 2012
  • The facilitated diffusion effect on protein-DNA binding is studied. A rigorous theoretical approach is presented to deal with the coupling between one-dimensional and three-dimensional diffusive motions. For a simplified model, the present approach can provide numerically exact results, which are confirmed by the lattice-based Monte Carlo simulations.

Olefin/Paraffin Separation though Facilitated Transport Membranes in Solid State

  • Hong, Seong-Uk;Won, Jong-Ok;Hong, Jae-Min;Park, Hyun-Chae;Kang, Yong-Soo
    • Proceedings of the Membrane Society of Korea Conference
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    • 1999.07a
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    • pp.15-18
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    • 1999
  • A simple mathematical model for facilitated mass transport through a fixed site carrier membrane was derived by assuming an instantaneous, microscopic concentration (activity) fluctuation. The current model demonstrates that the facilitation factor depends on the extent of concentration fluctuation, the time scale ratios of diffusion to chemical reaction and the ratio of the carrier concentration to the solute solubility in matrix. The model was examined against the experimental data on oxygen transport in membranes containing metallo-porphyrin carriers, and the agreement was exceptional (within 10% error). The basic concept of this approach was applied to separate olefin from olefin/paraffin mixtures. A proprietaty carrier, developed here, resulted that the selectivity of propylene over propane was more than 120 and the propylene permeance exceed 40 gpu.

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Numerical Analysis for the Geological Engineering Characteristics of Unconsolidated Sediment (미고결 퇴적물의 지질공학적 특성에 대한 수치해석적 연구)

  • CHO Tae-Chin
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.23 no.3
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    • pp.215-224
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    • 1990
  • Finite element model capable of solving coupled deformation-fluid diffusion equations for the fully saturated porous medium was developed using Galerkin's residual method. This model was used to study the mechanical and hydraulic behaviors of unconsolidated sediment near South Harbor, Pusan. The vertical displacement of top surface clay sediment, when subjected to the external load, is significantly affected by the excessive pore pres- sure buildup and its decay due to the pore fluid diffusion. The sand deposit overlain by the much less permeable clay layer serves as a flow channel. Consequently, the fluid diffusion due to pore pressure difference is significantly facilitated, which also affects the diffusion-dependent sediment deformation.

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International Joint Research for the Colloid Formation and Migration in Grimsel Test Site: Current Status and Perspectives

  • Sang-Ho Lee;Jin-Seok Kim;Bong-Ju Kim;Jae-Kwang Lee;Seung Yeop Lee;Jang-Soon Kwon
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.20 no.4
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    • pp.455-468
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    • 2022
  • Colloid Formation and Migration (CFM) project is being carried out within the Grimsel Test Site (GTS) Phase Ⅵ. Since 2008, the Korea Atomic Energy Research Institute (KAERI) has joined CFM to investigate the behavior of colloid-facilitated radionuclide transport in a generic Underground Research Laboratory (URL). The CFM project includes a long-term in-situ test (LIT) and an in-rock bentonite erosion test (i-BET) to assess the in-situ colloid-facilitated radionuclide transport through the bentonite erosion in the natural flow field. In the LIT experiment, radionuclide-containing compacted bentonite was equipped with a triple-packer system and then positioned at the borehole in the shear zone. It was observed that colloid transport was limited owing to the low swelling pressure and low hydraulic conductivity. Therefore, a postmortem analysis is being conducted to estimate the partial migration and diffusion of radionuclides. The i-BET experiment, that focuses more on bentonite erosion, was newly designed to assess colloid formation in another flow field. The i-BET experiment started with the placement of compacted bentonite rings in the double-packer system, and the hydraulic parameters and bentonite erosion have been monitored since December 2018.

Using TPC Model to Understand Broadband Diffusion in Korea (TPC(Technology, Policy and Culture) 모델을 이용한 한국의 초고속인터넷 확산 요인 분석)

  • Kum, Heisung
    • Informatization Policy
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    • v.17 no.3
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    • pp.74-97
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    • 2010
  • This paper investigates factors that have facilitated the rapid diffusion of broadband in South Korea. It finds that the quick spread of broadband access in South Korea is the result of combining the government's strategic ICT policy considering cultural traits, businesses'competitive efforts, and the timely explosion of domestic demand for IT service. This paper also discusses the impact of broadband diffusion on the digital divide. It finds that although there are still regional and age gaps in broadband access, the Korean government and businesses are working to alleviate these problems through various ways from systemic to physical ones. While the deployment of broadband cannot eliminate every issue of the digital divide, broadband access minimizes the digital divide by lowering the barrier to inequitable access to information. This paper concludes with a number of recommendations that address selected policy issues related to the spread of broadband Internet for its successful implementation.

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A Study on Utilization of ORCID based Author Identifier at National Level (국가 차원의 ORCID 기반 저자 식별자 활용에 관한 연구)

  • Kim, Eun-Jeong;Noh, Kyung-Ran
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.28 no.3
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    • pp.151-174
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    • 2017
  • The diffusion of the internet, the advancement of ICT technology, and digital diffusion have facilitated the streamlining and acceleration of scholarly communication and speeding up research, and the paradigm of scholarly information dissemination is changing. This study introduces the ORCID, a unique author identifier, and examines the ORCID organization's activities, the advantages given to researchers and research institutes, and the membership status. In addition, this paper examines adoptions and utilizations of ORCID in major countries including USA, UK, Italy, and China. Based on this, this paper suggests the necessary considerations for utilizing ORCID in terms of governance, system elements, policy and institutional aspects in an effort to identify authors at national level.

Effect of Mesoporous TiO2 in Facilitated Olefin Transport Membranes Containing Ag Nanoparticles (나노입자가 포함된 촉진수송 분리막에서의 메조기공 티타늄산화물의 영향)

  • Kim, Sang Jin;Jung, Jung Pyu;Kim, Dong Jun;Kim, Jong Hak
    • Membrane Journal
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    • v.25 no.5
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    • pp.398-405
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    • 2015
  • Facilitated transport is considered to be a possible solution to simultaneously improve permeability and selectivity, which is challenging in normal polymeric membranes based on solution-diffusion transport only. We investigated the effect of adding mesoporous $TiO_2$ ($m-TiO_2$) upon the separation performance of facilitated olefin transport membranes comprising poly(vinyl pyrrolidone), Ag nanoparticles, and 7,7,8,8-tetracyanoquinodimethane as the polymer matrix, olefin carrier, and electron acceptor, respectively. In particular, $m-TiO_2$ was prepared by means of a facile, mass-producible method using poly(vinyl chloride)-g-poly(oxyethylene methacrylate) graft copolymer as the template. The crystal phase of $m-TiO_2$ consisted of an anatase/rutile mixture, of crystallite size approximately 16 nm as determined by X-ray diffraction. The introduction of $m-TiO_2$ increased the membrane diffusivity, thereby increasing the mixed-gas permeance from 1.6 to 16.0 GPU ($1GPU=10^{-6}cm^3$(STP)/($s{\times}cm^2{\times}cmHg$), and slightly decreased the propylene/propane selectivity from 45 to 37. However, both the mixed-gas permeance and selectivity of the membrane containing $m-TiO_2$ rapidly decreased over time, whereas the membrane without $m-TiO_2$ had more stable long-term performance. This difference might be attributed to specific chemical interactions between $TiO_2$ and Ag nanoparticles, causing Ag to lose activity as an olefin carrier.

Effect of Hydrogen(H2) Addition on Flame Shape and Combustion Products in Mixed Coflow Diffusion Flames of Methane(CH4), Ethane(C2H6) and Propane(C3H8) (동축류 메탄(CH4), 에탄(C2H6), 프로판(C3H8) 혼합 확산화염내의 수소(H2) 첨가가 화염 형상 및 연소 생성물에 미치는 영향)

  • Park, Ho-Yong;Yoon, Sung-Hwan;Rho, Beom-Seok;Lee, Won-Ju;Choi, Jae-Hyuk
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.25 no.6
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    • pp.780-787
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    • 2019
  • As a carbon-free, green growth alternative, internal and external interest in hydrogen energy and technology is growing. Hydrogen was added to co-axial methane, methane-propane, and methane-propane-ethane diffusion flames, which are the main ingredients of LNG, to evaluate its effect on flame formation and combustion products. The variation in combustion products produced by adding hydrogen gradually to diffusion pyrolysis at room temperature and normal pressure conditions was observed experimentally by using a gas analyzer, and the shape of diffusion pyrolysis was observed step by step using a digital camera. The experimental results showed that the production volume of nitrogen oxides tended to increase and became close to linear as hydrogen was added to the diffusion pyrotechnic. This is because the relatively high temperature of heat insulation and fast combustion speed of hydrogen facilitated the production of thermal NOx. On the other hand, CO2 production tended to decrease as hydrogen was added to reduce the overall carbon ratio contained in the mixed diffusion flame of methane, methane-propane, and methane-ethane-propane. This means that the mixed fuel use of LNG-hydrogen in ships may potentially reduce emissions of CO2, a greenhouse gas.