• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.6
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• pp.710-716
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• 2013

The purpose of this study is to observe the movements of Five Mimic-Animal Boxing(FAB) by the "three barrier in the back" of Donguibogam. The subject of this study is observation of the movements of FAB according to practice. The term of training FAB is two years and six months. By the theory of "three barrier in the back" in Donguibogam, we analyzed the movements of FAB. The standard of judgement was the union of the basic point in the arm and leg & the action point in three barrier in the back. The study results were as follows. The movements of FAB operated on the three barrier in the back. The preliminary exercise operated on one, two, trree barrier in the back. And moreover the remainder exercise operated on one, two, trree barrier in the back. The movements of FAB operated on the three barrier in the back for the circulation of vital essence and energy. FAB is the very important Gigong exercise on opening the three barrier in the back.

• Microbiology and Biotechnology Letters
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• v.14 no.2
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• pp.181-186
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• 1986

A defective lambda transducing phase carrying acetyl CoA carboxylase gene (fabE) from Escherichia coli chromosome (72 min on the current linkage map) has been isolated. A restriction map of the chromosomal region from defective transducing phage was established by digestion with combination of the restriction enzymes. No cleavage site for the enzyme EcoRI was found in this region. Restriction fragments were cloned from defective transducing phage into high copy number plasmid vector pACYC184 to generate hybrid plasmids which were capable of complementation of fabE temperature sensitive mutation. We show here that the fabE gene is located on a 3.4 megadalton Bam HI-SalI fragment with a HindIII site, which lies within the 7.4 megadalton BglIIfragment, by complementation analysis.

• Journal of Microbiology and Biotechnology
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• v.18 no.8
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• pp.1475-1481
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• 2008

B3 antibody specifically binds the $Lewis^Y$-related carbohydrate antigen of many carcinomas, and it is used as a model antibody in this study. In a previous study, the Fab fragment of the antibody was fused to a 38 kDa truncated form of Pseudomonas exotoxin A, PE38, to make Fab-PE38, where PE38 is fused to the Fd fragment of the Fab domain. This parent monomer molecule, Fab-PE38, had no cysteine in the hinge region, and it could not make a disulfide bond to form a disulfide bond bridged homodimer. In this study, we constructed three different kinds of divalent Fab-toxin fusion homodimers where the toxin is fused to the light chain of Fab, $(Fab-PE38fl)_2$. In addition to the PE38 toxin fused to the light chain, these three molecules have different hinge sequences hi, h2, and h3 making Fabh1-, Fabh2-, and Fabh3-PE38fl monomers, respectively. These hinges contain only one cysteine on different positions of the hinge sequence. The disulfide bond between the hinge region of two monomers forms homodimers $(Fabh1-PE38fl)_2$, $(Fabh2-PE38fl)_2$, and $(Fabh3-PE38fl)_2$. The refolding yields of these dimers were 5-16-fold higher than a previously constructed dimer where the PE38 was fused to the Fd fragment $(Fabh2-PE38)_2$ [8]. Our data suggest that the steric repulsion between the two PE38s in $(Fabh1-PE38)_2$ during disulfide bridge formation is relieved by fusing it at the end of the light chain. The best cytotoxicity value of these dimers showed about 2.5-fold higher on an MCF7 cell line than that of the monovalent reference molecule in ng/ml scale, which is 15-fold higher in pM scale.

• Proceedings of the IEEK Conference
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• 2008.06a
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• pp.481-482
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• 2008

In this paper, the advanced process has been presented to remove the WSix peeling that was made in sub 100nm DRAM SRCAT(Sphere-shaped-Recess-Ch annel-Array Transistor). The source of WSix peeling was proved to be the groove of gate poly film. We have completely solved the problems to adopt the gate-poly CMP (Chemical Mechanical Polishing) process.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2006.05a
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• pp.1765-1770
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• 2006

본 논문에서는 반도체 fab 라인의 물류 설비를 event graph로 모델링 하는 방법론을 제안하고 있다. 최근 반도체 fab 라인 같은 대표적인 자본 집약적 제조라인에서는 운영단계에서 투입 계획, PM schedule 및 operation rule 등을 변화시켜 가며 평가 및 검증해 볼 수 있는 what-if simulation을 위한 line simulator의 필요성이 점점 높아지고 있다. 그러나 상용 simulator는 각 제조라인의 특성에 맞게 customization하는데 많은 시간과 비용이 소요될 뿐만 아니라 특성을 반영하는데 한계가 있다. 따라서 이러한 line simulator를 개발할 때 근간이 되는 설비의 simulation model이 필요하다. 이 때 설비들은 생산(processing) 및 물류(handling) 설비로 나눌 수 있는데, 본 논문에서는 반도체 fab 라인의 물류 설비 모델링 방법을 제시하고 실제 물류 설비를 모델링 해 봄으로써 그 효용성을 알아본다.

• Journal of the Semiconductor & Display Technology
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• v.3 no.4
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• pp.51-55
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• 2004

In the design stage of high precision manufacturing/inspection FAB facilities, it is necessary to investigate the allowable vibration limits of high precision equipments and to study structural dynamic characteristics of C/R and Sub-structure in order to provide structural vibration criteria to satisfy these allowable limits. The goal of this study is to investigate the dynamic characteristics of PC-Type mock-up structures designed for next generation TFT-LCD FAB through experiments and analysis procedures. Therefore, in order to provide a proper dynamic structural design for high precision manufacturing/inspection work process, these allowable limits must be satisfied.

• Archives of Pharmacal Research
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• v.17 no.6
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• pp.452-457
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• 1994

The water soluble long-chain crosslinker, sulfo-succinimidyl-6-[3'-(2-pyridyldithio)-propion-amido]hexanoate (S-LC-SPDP) was used to prepare ricin A chain (RAT) immunotoxins constructed with whole igG and Fab fragments of the anti-common acute lymphoblastic leukemiz antigen (CALLA)monoclonal antibody. In this study, a) S-LC-SPDP modification efficiencies immunoreactivity and cytotoxicity of immunotoxins constructed were examined. IgG-RTA and Fab-RTA immunotoxins were prepared with 67.3% and 57.0% conjugation yields, respectively. These long spacer intemolecular linked immunotoxins were selectively immunoreactive and to antigen K562 cells. Both IgG-RAT and Fab-RAT immunotoxins were 210-and 45-fold more active than intavt RAT in vitro, respectively.

• Proceedings of the Korea Society for Simulation Conference
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• 1999.10a
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• pp.30-34
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• 1999

반도체 산업의 시장은 매년 증가하고 있으며 생산환경, 설비 등의 변화로 인하여 매년 많은 수의 기존 FAB Line이 변화되고 새로이 건설되고 있다. 그 동안 반도체 산업의 성장은 주로 설계기술, 설비기술, Chip Size의 소형화 등의 기술적인 개발에 의존하고 있었으나 반도체 기술의 확산, 시장 경쟁력의 격화 등으로 생산성 향상에 의한 원가절감이 성장의 근본요인이 되고 있다. 즉 FAB Line의 시스템적인 관리통제의 기술이 반도체 산업의 성패를 좌우하는 시대로 접어든 것이다. FAB Line은 크게 Bay와 Stocker, 각 Lot (또는 Batch) 들을 운반하는 Inter-System으로 구성된다. 이러한 Line은 대체 특성, 분기 현상, 돌발 상황 등의 특수한 경우가 많아 Analytic 모델로 접근하기에는 사실상 불가능하다. 특히 Stocker와 Bay 간의 이동은 더욱 그렇다. 따라서 적절한 설계과정을 거친 Simulation적 접근이 합리적이다. 본 논문에서는 FAB Line에서 Stocker 배치의 다양한 실험을 수행하였다. 그 결과 Line에서 최적의 Stocker 수와 가동률을 알아내었다. 반도체 생산라인에서는 제품별 또는 같은 제품이라도 Version이 다른 경우 FAB 공정가운데 약 10% 내외만이 바뀌는 점을 감안하면 본 논문의 결과는 쉽게 생산현장에 적용될 수 있을 것이며, 이것은 비단 반도체 공정뿐 아니라 제조업에서도 적용되리라 예상한다.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.34 no.4
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• pp.189-196
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• 2011

In this paper, we propose a logical control-based actor-critic algorithm as an efficient approach for the approximation of the capacitated fab scheduling problem. We apply the average reward temporal-difference learning method for estimating the relative value functions of system states, while avoiding deadlock situation by Banker's algorithm. We consider the Intel mini-fab re-entrant line for the evaluation of the suggested algorithm and perform a numerical experiment by generating some sample system configurations randomly. We show that the suggested method has a prominent performance compared to other well-known heuristics.

• Analytical Science and Technology
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• v.6 no.3
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• pp.335-343
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• 1993

The structure of cerebrosides from soybean embryo was determined using fast atom bombardment mass spectrometer (FAB-MS), gas chromatography mass spectrometer (GC-MS) and TLC. The components of cerebroside were determined by GC-MS after acid hydrolysis. The molecular weight distribution of cerebroside was measured by positive mode FAB-MS with LiOH saturated 3-nitrobenzylalcohol(3-NBA) matrix. Structures of individual components of complex mixtures can be determined easily by this process. The major constituent of soybean extracted cerebroside was determined as the glucoside of N-2'-hydroxypalmitoyl-sphingadienine.