• Journal of Biomedical Engineering Research
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• v.30 no.2
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• pp.135-141
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• 2009

Purpose: The aim of present study is to evaluate a possibility of clinical application for the effect of low intensity ultrasound stimulation (LIUS) in mechanical characteristics of bone on osteoporotic fractures prevention. Materials and Methods: Eight virgin ICR mice (14 weeks old, approximate weight 25g) were ovariectomized (OVX) to induce osteoporosis. The right hind limbs were then stimulated with LIDS (US Group), whereas left hind limbs were not stimulated (CON Group). Both hind limbs of all mice were scanned by in-vivo micro-CT to acquire two-dimensional (2D) images at 0 week before stimulation and 3 weeks and 6 weeks after stimulation. Three-dimensional (3D) finite element (FE) models generated by scanned 2D images were used to determine quantitatively the effect of LIUS on strength related to bone structure. Additionally, distributions of Hounsfield units and elastic moduli, which are related to the bone quality, for the bones in the US and CON groups were determined to analyze quantitatively a degree of improvement of bone qualities achieved by LIUS. Results: The result of FE analysis showed that the structural strength in US Group was significantly increased over time (p<0.05), while that in CON Group was statistically constant over time (p>0.05). High values of Hounsfield units obtained from voxels on micro-CT images and high values of elastic moduli converted from the Hounsfield units were dominantly appeared in US Group compared with those in CON Group. Conclusion: These finding indicated that LIUS would improve the mechanical characteristics of osteoporotic bone via the effects of bone structure (bone strength) and quality (Hounsfield unit and elastic modulus). Therefore, the LIUS may decrease effectively the risk of osteoporotic fracture in clinics.

• Journal of Biomedical Engineering Research
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• v.38 no.1
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• pp.9-15
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• 2017

Recently, flexible cages have been introduced in an attempt to absorb and reduce the abnormal load transfer along the anterior parts of the spine. They are designed to be used with the pedicle screw systems to allow some mobility at the index level while containing ROM at the adjacent level. In this study, a finite element (FE) study was performed to assess biomechanical efficacies of the flexible cage when combined with pedicle screws with flexible rods. The post-operated models were constructed by modifying the L4-5 of a previously-validated 3-D FE model of the intact lumbar spine (L2-S1): (1) Type 1, flexible cage only; (2) Type 2, pedicle screws with flexible rods; (3) Type 3, interbody fusion cage plus pedicle screws with rigid rods; (4) Type 4, interbody fusion cage plus Type 2; (5) Type 5, Type 1 plus Type 2. Flexion/extension of 10 Nm with a compressive follower load of 400N was applied. As compared to the Type 3 (62~65%) and Type 4 (59~62%), Type 5 (53~55%) was able to limit the motion at the operated level effectively, despite moderate reduction at the adjacent level. It was also able to shift the load back to the anterior portions of the spine thus relieving excessively high posterior load transfer and to reduce stress on the endplate by absorbing the load with its flexible shape design features. The likelihood of component failure of flexble cage remained less than 30% regardless of loading conditions when combined with pedicle screws with flexible rods. Our study demonstrated that flexible cages when combined with posterior dynamic system may help reduce subsidence of cage and degeneration process at the adjacent levels while effectively providing stability at the operated level.

• Journal of the Korean earth science society
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• v.27 no.5
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• pp.557-568
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• 2006

We present CCD UBVI photometry for more than 10,000 stars in $20'.5{\times}20'.5$ field of the halo globular cluster M30. From a color-magnitude diagram, main sequence turnoff was obtained when $V_{TO},\;(B-V)_{TO},\;and\;(V-I)_{TO}\;are\;8.63{\pm}0.05,\;0.44{\pm}0.05\;and\;0.63{\pm}0.05$, respectively. From a (U-B)-(B-V) diagram, reddening parameter, E(B-V) equals $0.05{\pm}0.01$ and a UV color excess ${\delta}(U-B)\;is\;0.27{\pm}0.01$. The abundance is derived, where [Fe/H] equals $-2.05{\pm}0.09$ according to the photometric method and spectroscopic data. The observed luminosity function of M30 shows an excess in the number of red giants relative to the number of turnoff stars, when comparing with the predictions of canonical models. Using the Hipparcos parallaxes for subdwarfs, we estimate distance modulus, $(m-M)_o\;as\;14.75{\pm}0.12$. Using the R and R' method, we find helium abundances, Y(R) as $0.23{\pm}0.02$, Y(R') as $0.29{\pm}0.02$, respectively. Finally, the cluster' sage dispersion was deduced from 10.71 Gyr to 17 Gyr.

• Journal of Environmental Impact Assessment
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• v.29 no.4
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• pp.272-285
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• 2020

We investigated statistical evaluation parameters for 3D meteorological and air quality models and selected several quantitative indicator references, and summarized the reference values of the statistical parameters for domestic air quality modeling researcher. The finally selected 9 statistical parameters are MB (Mean Bias), ME (Mean Error), MNB (Mean Normalized Bias Error), MNE (Mean Absolute Gross Error), RMSE (Root Mean Square Error), IOA (Index of Agreement), R (Correlation Coefficient), FE (Fractional Error), FB (Fractional Bias), and the associated reference values are summarized. The results showed that MB and ME have been widely used in evaluating the meteorological model output, and NMB and NME are most frequently used for air quality model results. In addition, discussed are the presentation diagrams such as Soccer Plot, Taylor diagram, and Q-Q (Quantile-Quantile) diagram. The current results from our study is expected to be effectively used as the statistical evaluation parameters suitable for situation in Korea considering various characteristics such as including the mountainous surface areas.

• Journal of Korean Society of Steel Construction
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• v.21 no.1
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• pp.63-70
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• 2009

Failure modes result in fracture or tearing, which may cause deterioration of resistance and reduction of inelastic deformation capacity. The potential failure modes for Special Concentrically Braced Frames (SCBFs) include fracture or tearing of the brace, net section fracture of the brace or gusset plate, fracture of the gusset plate welds, shear fracture of the bolts, block shear, excessive bolt bearing deformation, and buckling of the gusset plate. HSS tubular braces are commonly used in SCBFs, and net section fracture of the tubular brace may also occur through the brace net section at the end of the slot cut into the tube to slip over the gusset plate. This failure mode is categorized as a tension failure mode, and may cause dramatic loss of resistance and brittle behavior. Net section reinforcement is required according to AISC design specifications (AISC 2001). In this paper, the need to reinforce the net section area was discussed. Initially, the results of the net section fracture tests done by the University of California in Berkeley were presented with the modeling of these tests using FE models. To investigate the possibility of net section fracture in an actual frame, the slot end hole model was adapted to the frame FE model, and alternate near-fault histories were applied with tension-dominated cycles, since previous analyses showed that loading history was the most critical factor in net section fracture. The need for this reinforcement (cover plate) and the tension-dominated near-fault history were investigated.

• Spatial Information Research
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• v.14 no.1 s.36
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• pp.129-150
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• 2006

Mineral potential mapping is an important procedure in mineral resource assessment. The purpose of this study is to analyze mineral potential using weight of evidence model and a Geographic Information System (GIS) environment to identify areas that have not been subjected to the same degree of exploration. For this, a variety of spatial geological data were compiled, evaluated and integrated to produce a map of potential mineral in the Gangreung area, Korea. for this, a spatial database considering mineral deposit, topographic, geologic, geophysical and geochemical data was constructed for the study area using a GIS. The used mineral deposits were non-metallic(Kaolin, Porcelainstone, Silicastone, Mica, Nephrite, Limestone and Pyrophyllite) deposits of sedimentary type. The factors relating to mineral deposits were the geological data such as lithology and fault structure, geochemical data, including the abundance of Al, As, Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Li, Mg, Mn, Mo, Na, Ni, Pb, Si, Sr, V, Zn, $Cl^-,\;F^-,\;{PO_4}^{3-},\;{NO_2}^-,\;{NO_3}^-,\;SO_{42-}$, Eh, PH and conductivity and geophysical data, including the Bouguer and magnetic anomalies. These factors were used with weight of evidence model to analyze mineral potential. Probability models using the weight of evidence were applied to extract the relationship between mineral deposits and related factors, and the ratio were calculated. Then the potential indices were calculated by summation of the likelihood ratio and mineral potential maps were constructed from Geographic Information System (GIS). The mineral potential maps were then verified by comparison with the known mineral deposit areas. The result showed the 85.66% in prediction accuracy.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.29 no.1
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• pp.85-93
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• 2016

In this study, finite element analyses of masonry infilled frames using a general purpose FE program, ABAQUS, were conducted. Analysis models consisted of the bare frame, infilled frames with masonry wall thickness of 0.5B and 1.0B, respectively. The masonry walls were constructed using the concrete bricks which were generally used in Korea as infilled wall. The material properties of frames and masonry for the analysis were obtained from material tests. However, four times increased the tensile strength was used for 1.0B wall, which is seemingly due to the differences in locating the bricks. The force-displacement relation and development of crack from the FE analysis were very similar to those from the experiments. From the FEA results, contact force between the frame and masonry, distribution of shear force and bending moments in frame members were analyzed. Obtained contact stress shows a trianglur distribution, and the contact length for 0.5B speciment and 1.0B specimen were close to the value estimated using ASCE 41-06 equation and ASCE 41-13 equation, respectively. Obtained shear force and bending moment distribution seems to replicate actual behavior which originates from the contact stress and gap between the frame and masonry.

• Journal of Life Science
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• v.23 no.2
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• pp.249-258
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• 2013

The antioxidative activity and bioactivity of water, ethanol, and methanol extracts from Paecilomyces japonica (PJ), Cordyceps militaris (CM), and cordycepin-enriched C. militaris JLM0636 ($CM{\alpha}$) were tested in in vitro experimental models. The PJ water extract showed the highest extraction yield (42.53%). The highest content of phenolic compounds and flavonoids were found in the water extract of PJ, 2.72% and 1.73%, respectively. The major minerals were K, Mg, and Ca. The water extracts of PJ also showed the highest DPPH free radical scavenging activity and reducing power. Linoleic acid peroxidation and antioxidative activities were strong in $CM{\alpha}$. The methanol extracts of PJ showed the highest inhibition activity against tyrosinase. Fibriolytic activity was higher in $CM{\alpha}$ than in CM. These results may provide basic data to understand the biological activities of bioactive materials derived from $CM{\alpha}$ for the development of functional foods, cosmetics, and antithrombotics.

• Journal of the Society of Disaster Information
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• v.17 no.4
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• pp.747-754
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• 2021

Purpose: Seismic safety evaluation of a curved bridge must be performed since the curved bridges exhibit the complex behavior rather than the straight bridges, due to geometrical characteristics. In order to conduct the probabilistic seismic assessment of the curved bridge, Seismic fragility evaluation was performed using the uncertainty of the steel material properties of a curved bridge girde, in this study. Method: The finite element (FE) model using ABAQUS platform of the curved bridge girder was constructed, and the statistical parameters of steel materials presented in previous studies were used. 100 steel material models were sampled using the Latin Hypercube Sampling method. As an input ground motion in this study, seismic fragility evaluation was performed by the normalized scale of the Gyeongju earthquake to 0.2g, 0.5g, 0.8g, 1.2g, and 1.5g. Result: As a result of the seismic fragility evaluation of the curved girder, it was found that there was no failure up to 0.03g corresponding to the limit state of allowable stress design, but the failure was started from 0.11g associated with using limit state design. Conclusion: In this study, seismic fragility evaluation was performed considering steel materials uncertainties. Further it must be considered the seismic fragility of the curved bridge using both the uncertainties of input motions and material properties.

• Journal of the Korea institute for structural maintenance and inspection
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• v.23 no.2
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• pp.67-74
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• 2019

In this paper the response factor is investigated for middle and small size-RC slab aged bridges. The response factor consists of static and dynamic response factors and is a main parameter in the frequency based-bridge load carrying capacity prediction model. Static and dynamic response factors are determined based on the frequency variation and the impact factor variation respectively between current and previous (or design) states of bridges. Here, the impact factor variation is figured out using the impact factor response spectrum which provides the impact factor according to the natural frequency of bridges. In this study, four actual RC slab bridges aged over 30 years after construction are considered and their span length is 12m. The dynamic loading test in field using a dump truck and eigenvalue analysis with FE models are conducted to identify the current and previous (or design) state-natural frequencies of the bridges, respectively. For more realistic considerations in the moving loading situation, the impact factor response spectrum is developed based on tri-axle moving loads representing the dump truck load distribution and various supporting conditions such as simply supported and both ends fixed conditions. From the results, the response factor is widely ranged from 0.21to 0.91, showing that the static response factor contributes significantly on the results while the dynamic response factor has a small effect on the result. Compared to the results obtained from the impact factor response spectrum based on the single axle-simply supported condition, the maximum percentage difference of the response factors is below 3.2% only.