• Journal of Embryo Transfer
• /
• v.25 no.4
• /
• pp.273-279
• /
• 2010

Follicular cystic follicles (FCFs) show delayed regression with persistent follicle growth. However, the mechanism by which follicles are persistently grown remains unclear. Glutathione S-transferases (GSTs) are drug-metabolizing and detoxification enzymes that are involved in the intracellular transport and metabolism of steroid hormones. In this study, a proteomic analysis was performed to identify whether GST expression is changed in bovine FCFs and to predict the interactions between GST and other proteins. Normal follicles and FCFs were classified based on their sizes (5 to 10 mm and 25 mm). In bovine follicles, GST mu 1 (GSTM1) was detected as a differentially expressed protein (DEP) and significantly up-regulated in FCFs compared to normal follicles (p<0.05). Consistent with the proteomic results, semi-quantitative PCR data and western blot analysis revealed an up-regulation of GSTM1 in FCFs. Expression levels of aromatase and dehydrogenase proteins were changed in FCFs. These results show that the up-regulation of GSTM1 that is observed in bovine FCFs is likely to be responsible for the persistent follicle growth in FCFs as the activity of aromatase and the dehydrogenases.

• Journal of Korea Multimedia Society
• /
• v.9 no.7
• /
• pp.827-834
• /
• 2006

In distributed virtual environment, system response time to users' interactions is an importance factor to determine the degree of contentment with the system. Generally, response time is affected by the efficiency of event message processing algorithm, and most of previous systems use FCFS algorithm, which processes message traffic sequentially based only on the event occurrence time. Since this method totally depends on the order of occurrence without considering the priorities of events, it has a problem that might drop the degree of system response time by causing to delay processing message traffic when a bottleneck phenomenon happens in the server side. To overcome this limitation of FCFS algorithm, this paper proposes a concurrent event scheduling algorithm, which is able to process event messages concurrently by assigning the priorities to the events. It is also able to satisfy the two goals of system together, consistency and responsiveness through the combination of occurrence time with priority concept of events.

• The Korean Journal of Physiology and Pharmacology
• /
• v.14 no.5
• /
• pp.265-272
• /
• 2010

Follicular cystic ovary (FCO) is one of the most frequently diagnosed ovarian diseases and is a major cause of reproductive failure in mammalian species. However, the mechanism by which FCO is induced remains unclear. Genetic alterations which affect the functioning of many kinds of cells and/or tissues could be present in cystic ovaries. In this study, we performed a comparison analysis of gene expression in order to identify new molecules useful in discrimination of bovine FCO with follicular cystic follicles (FCFs). Normal follicles and FCFs were classified based on their sizes (5 to 10 mm and $\geq25mm$). These follicles had granulosa cell layer and theca interna and the hormone $17{\beta}$-estradiol ($E_2$)/ progesterone ($P_4$) ratio in follicles was greater than one. Perifollicular regions including follicles were used for the preparation of RNA or protein. Differentially expressed genes (DEG) that showed greater than a 2-fold change in expression were screened by the annealing control primer (ACP)-based PCR method using $GeneFishing^{TM}$ DEG kits in bovine normal follicles and FCFs. We identified two DEGs in the FCFs: ribosomal protein L15 (RPL15) and microtubule-associated protein 1B (MAP1B) based on BLAST searches of the NCBI GenBank. Consistent with the ACP analysis, semi-quantitative PCR data and Western blot analyses revealed an up-regulation of RPL15 and a down-regulation of MAP1B in FCFs. These results suggest that RPL15 and MAP1B may be involved in the regulation of pathological processes in bovine FCOs and may help to establish a bovine gene data-base for the discrimination of FCOs from normal ovaries.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.21 no.10
• /
• pp.2586-2596
• /
• 1996

The handover area is the region where a call can be handled by the base stations in any of the adjacent cells, and handover duration time is viewed as the time an mobile station resides inthe handover area. In this paper, analytic model to estimate the distribution function(df) of the handover duration time is proposed. Based on the df of the handover duration time, the simulation and anlytic models for the First Come first Serve(FCFS) scheme are presented, and the simulation results for the Measurement Based Prioritization Scheme(MBPS) are compared with the analytic results of the FCFS handover scheme. Those results show that the MBPS scheme is seen to provide lower handover failures than FCFS queueing with slightly increasing the new call blocking probability.

• Journal of Food Hygiene and Safety
• /
• v.35 no.5
• /
• pp.459-467
• /
• 2020

In this study, we investigated the changes in both ambient temperature and microbial contamination of fresh convenience foods (FCFs) caused by the behavior of consumers after purchase. According to consumer survey results, it took 0.5 to 3 h put the purchased FCF in a home refrigerator or consume it. Only aerobic bacteria and Staphylococcus aureus (below maximum permitted limit) were detected in FCFs obtained from a local market. During storage of FCFs in a vehicle trunk for up to 3 h. the external and internal temperatures of FCFs were found to be 19 and 18.5℃ in spring, 44 and 42℃ in summer, 31.3 and 29.2℃ in autumn, and 17.6 and 16.8℃ in winter, respectively. Changes in contamination levels of aerobic bacteria on FCFs stored in a vehicle trunk for up to 3 hours are as follows: 2.72 → 3.41 log CFU/g in spring, 3.11 → 4.32 log CFU/g in summer, 3.08 → 3.81 log CFU/g in autumn, 2.71 → 3.36 log CFU/g in winter. S. aureus exceeding the tolerance was detected even when the FCFs were stored in a vehicle trunk for 1 h in summer and autumn and 2 h in spring and winter. Among three boxes (corrugated box, styrofoam box, and corrugated box coated with an aluminum film), the styrofoam box maintained the lowest temperature and showed the lowest growth rate of microorganisms on FCF after storage for 3 h in the vehicle trunk depending on whether ice was added. These results indicated that the possibility of food poisoning occurs when FCFs are exposed to the external environment. It is necessary to provide guidelines regarding storage temperature and allowable time for safe consumption of FCFs after purchase.

• The KIPS Transactions:PartA
• /
• v.8A no.3
• /
• pp.245-252
• /
• 2001

Multicomputer systems achieve high performance by utilizing a number of computing nodes. Multidimensional meshes have become popular as multicomputer architectures due to their simplicity and efficiency. In this paper we propose an efficient processor allocation scheme for 3D torus based on first-fit approach. The scheme minimizes the allocation time by effectively manipulating the 3D information an 2D information using CST (Coverage Status Table). Comprehensive computer simulation reveals that the allocation time of the proposed scheme is always smaller than the earlier scheme based on best-fit approach, while allowing comparable processor utilization. The difference gets more significant as the input load increases. To investigate the performance of the proposed scheme with different scheduling environment, non-FCFs scheduling policy along with the typical FCFS policy is also studied.

• Journal of Embryo Transfer
• /
• v.28 no.1
• /
• pp.57-61
• /
• 2013

Microtubule-associated protein 1B (MAP1B), a member of MAP1 family, plays a key role in neuronal development. MAP1B binds to many kinds of proteins directly or indirectly. This study was performed to investigate whether MAP1B interacts with GAPDH in bovine follicles using immunoprecipitation (IP) with Western blot analysis and immunohistochemisty. The mRNA expressions of MAP1B and glyceraldehydes 3-phosphate dehydrogenase (GAPDH) were down-regulated in bovine follicular cystic follicles (FCF). In parallel with the mRNA levels, their protein levels were also down-regulated in FCFs. In addition, MAP1B and GAPDH were co-localized at the cytoplasm of follicles. IP with Western blot analysis showed that MAP1B bound to GAPDH in normal follicles, but their binding was absent in FCFs, suggesting a low level of MAP1B and/or GAPDH expressions in FCFs. Taken together, these results suggest that MAP1B interacted with GAPDH may play a role in bovine follicle development, and that GAPDH does not function always as a loading control in bovine follicles.

• Proceedings of the Korean Institute of Communication Sciences Conference
• /
• 1992.06a
• /
• pp.50-53
• /
• 1992

• Journal of Korean Institute of Industrial Engineers
• /
• v.33 no.1
• /
• pp.26-32
• /
• 2007

This study deals with waiting-time dependent backordering rate during stock-out period in the EconomicProduction Quantity (EPQ) model. Assuming that the backordering rate follows an exponentially decreasingfunction of the waiting time, the backorder rate is developed under First-Come-First-Served (FCFS) andLast-Come-First-Served (LCFS) Policy. The mathematical models are developed based on differential equations.Through numerical examples, the validity of the developed models is illustrated.

• Journal of the Korean Operations Research and Management Science Society
• /
• v.35 no.2
• /
• pp.1-17
• /
• 2010

This paper aims to compare four operating priority rules of RMGC (Rail Mounted Gantry Crane) used in semi-automated container terminal. The four priority rules employed in this paper are FCFS (First-come-first-served), LCFS (Last-come-first-served), TOS (Turn-over-served) and NFS (Nearest-first-served). And to compare the four operating priority rules, this paper analyzed productivity of RMGC and CC (Container Crane), waiting time of YT (Yard Truck) and RT (Road Truck) in container yard, and turnaround time of RT in container terminal of each priority rule by using stevedoring simulation. As a result, NFS was evaluated as the best rule to improve the overall productivity of container terminal in terms of all criteria.