• Title/Summary/Keyword: FCA

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Analysis of Microsatellite Markers for Forensic Identification in cats (고양이의 개체식별을 위한 microsatellite marker 분석)

  • Cho Gil-Jae
    • Journal of Life Science
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    • v.16 no.3 s.76
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    • pp.382-386
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    • 2006
  • A total number of 20 cat samples including 8 parentage testing and 12 individual identification were genotyped. Genomic DNA was extracted from buccal swab, and genotyped by using 10 microsatellite markers (FCA005, FCA26, FCA224, FCA240, FCA453, FCA293, FCA075, FCA105, FCA229, and FCA651). This method consisted of single PCR procedure and showed reasonable amplification of all PCR products. Genotypes were determined by genetic analyzer. The number of alleles per locus of cats varied from 3 to 8 with a mean value of 5.5. Expected heterozygosity was ranged from 0.390 to 0.827 (mean 0.639) and the total exclusion probability of 10 microsatellite loci was 0.9441. Of the 10 markers, FCA240 marker has relatively high PIC value (>0.7). Of the 8 cats, 7 cats were qualified by compatibility according to the Mendelism. These results can give basic information for developing parentage verification and individual identification system in cat.

FCA-Based Ontology Augmentation (FCA 기반의 온톨로지 확장)

  • 김현식;김인철
    • Proceedings of the Korean Information Science Society Conference
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    • 2004.10a
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    • pp.145-147
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    • 2004
  • 기존 온톨로지를 확장하는 한 가지 방법은 기존의 기초 개념들로부터 새로운 하위 개념들을 유도해 내거나 개념들간의 새로운 관계들을 발견해내는 것이다. 본 논문에서는 의학분야의 기존 온톨로지를 확장하는데 정형적 개념 분석(FCA) 방법이 갖는 잠재적 역할을 분석해보자 한다. 이를 위해 우리는 영역 특정 문서들로부터 기존 개념들의 실례(instance)들을 추출할 수 있다고 가정한다. 본 논문에서는 3 단계로 이루어진 FCA기반의 은톨로지 확장 방법론을 설명하고, MeSH 온톨로지 확장에 관한 경험을 소개한다.

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Suppressing Effects of Sowhalrack-dan(Xiǎohuóluò-dān) on Freund's Complete Adjuvant Induced Arthritic Rats (Adjuvant 유발(誘發) 류마티스 관절염(關節炎)에 대한 소활락단(小活絡丹)의 억제(抑制) 효과(效果))

  • Yun, Sun-Mo;Jeong, Man-Jin;Kwon, O-Gon;Woo, Chang-Hoon;An, Hee-Duk
    • Journal of Korean Medicine Rehabilitation
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    • v.21 no.1
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    • pp.97-114
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    • 2011
  • Objectives : The object of this study is to observe the favorable anti arthritic effects of Sowhalrack-dan($Xi\check{a}ohu\acute{o}lu\grave{o}-d\bar{a}n$)(SWRD), which has been traditionally used in Korean medicine to treat rheumatoid arthritis on Freund's complete adjuvant(FCA) induced arthritic Wistar rats. Methods : Rheumatoid arthritis was induced by intradermal injection of FCA(10 mg in 1 ml paraffin oil 0.1 ml/rats). Each of 8 rats showing regular ankle circumferences per group were selected in 14 days after FCA treatment to confirm the induction of rheumatoid arthritis. 300, 150 or 75 mg/kg of SWRD was orally administered once a day for 14 days from 14 days after FCA treatments. Dexamethasone was intraperitoneally administered 15 mg/kg, once a day for 14 days from 14 days after FCA treatments. Rats were sacrificed after 14 days of continuous oral treatment of SWRD or intraperitoneal administration of dexamethasone, and changes were observed; the body weight, knee circumferences, gross arthritis score, inflammatory tissue $prostaglandin(PG)E_2$ levels and cartilage collagen, glucosaminoglycans compositions - chondroitin sulphate, heparin sulphate and hyaluronic acid in the present study. Results : As results of FCA treatment, classic rheumatoid arthritis featuring dramatical decreases on the body weights, cartilage collagen contents and bone glucosaminoglycans - chondroitin sulphate, heparin sulphate and hyaluronic acid contents. Also, it increases the knee circumferences, gross arthritis scores and inflammatory tissue $PGE_2$ levels. However, these changes from FCA induced rheumatoid arthritis were clearly reduced due to the dexamethasone and both two different dosages of SWRD, 300 and 150 mg/kg in the present study. Although FCA induced arthritis were more favorably inhibited by treatment of dexamethasone 15 mg/kg compared to SWRD 300 mg/kg, marked decreases of body weights were detected in dexamethasone 15 mg/kg treated rats. Conclusions : The results obtained in this study suggest that over 150 mg/kg of SWRD showed favorable anti-arthritic effects on the FCA induced arthritis mediated by suppression of $PGE_2$. However, detailed mechanism studies are needed with the screening of the biological active compounds in SWRD. Although FCA induced arthritis were more favorably inhibited by treatment of dexamethasone 15 mg/kg compared to SWRD 300 mg/kg, marked decreases of body weights were detected in dexamethasone 15 mg/kg treated rats, in the present study.

The effects of adjuvants and vaccine against edwardsiellosis in tilapia, Oreochromis nioticus (틸라피아의 에드와드병에 대한 백신과 Adjuvant의 효과)

  • Lee, Joo-Seok;Park, Soo-Il
    • Journal of fish pathology
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    • v.5 no.1
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    • pp.19-27
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    • 1992
  • A formalized bacterin(FKC) of Edwardsiella tarda, conjugated with/without Freund's complete adjuvant(FCA), Freund's incomplete adjuvant(FIA) and potassium aluminium sulfate(PAS), was administered by intraperitoneal injection to tilapia respectively. The tilapia were reared under indoor recirculating filter system. There were agglutinin titer increment in the tilapia which were administered not only FKC bacterin but also adjuvanted vaccines. But the producing time of the highest level of antibody in the immunized tilapia was different among vaccine preparation, i. e. FKC+FCA group and PAS+FKC group are between the 2nd and the 4th week, and FKC alone group is the 2nd week. In the challenge experiment with $2.5{\times}10^7\;CFU/ml$ or $2.5{\times}10^8\;CFU/ml$ of E. tarda T1123 to the tilapia immunized with vaccines, RPS above sixty was recorded both challenge dose in the tilapia which were 3 weeks after immunization with FKC+FCA, PAS+FKC and FKC alone, and the former dose 8 weeks after immunization with FCA+FKC and PAS+FKC. There were some resistance enhancement against E. tarda in the tilapia which were injected with adjuvant alone than that of control. As the results, the FCA or PAS adjuvanted vaccine is effective to sustain the defensible period against edwardsiellosis.

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A Study on the Perception Difference of the Farm-Closure Assistance Program by Local Government Officials' Characteristics (지자체 공무원 특성에 따른 폐업지원제도 인식 차이 연구)

  • Lee, Hyun-Keun;Chai, Sang-Hyen;Choi, Mira
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.10
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    • pp.406-414
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    • 2020
  • The Farm-Closure Assistance (FCA) program is operated to compensate for lost farm income, to stabilize the management of low-competitive farms, and to enhance competitiveness of target items. The FCA, however, has several problems, such as the balloon effect and fraudulent receipts. Therefore, it is important to examine the operational problems of the FCA, establish improvement plans, and settle the measures. The objectives of this study are to analyze problems and suggest solutions for FCA, reflecting the viewpoints of local government officials who are in charge of actual tasks on the FCA front lines. The study analyzes whether characteristics of government officials lead to differences in setting the maximum amounts and extensions to FCA. Factors influencing the necessity of setting ceilings on FCA were work experience, recognition of agriculture's importance, and the FTA's impact on domestic agriculture, gender, and regions. Factors affecting the extension of FCA were the agency unit, work experience on the FTA, recognition of the effects of FTA direct payments and FCA, and recognition of the subsidy's direction. The results can be employed as a fundamental background that can set the direction for institutional improvement when the government tries to improve FCA.

The Development of an Automatic Tool for Formal Concept Analysis and its Applications on Medical Domain (형식개념분석을 위한 자동화 도구의 개발과 의료분야에서의 적용사례)

  • Kim, Hong-Gee;Kang, Yu-Kyung;Hwang, Suk-Hyung;Kim, Dong-Soon
    • The KIPS Transactions:PartD
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    • v.13D no.7 s.110
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    • pp.997-1008
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    • 2006
  • For extracting and processing information explicitly from given data, Formal Concept Analysis(FCA) is provided a method which is widely used for data analysis and clustering. The data can be structured into concepts, which are formal abstractions human thought allowing meaningful comprehensible interpretation. However, most FCA tools mainly focus on analyzing one-valued contexts that represent objects, attributes and binary relations between them. There we few FCA tools available that provide scaling and analyzing many-valued contexts representing objects, attributes and relations with attributes' values. In this paper, we propose not only a scaling algorithm for interpreting and simplifying the multivalued input data, but also an algorithm to generate concepts and build concept hierarchy from given raw data as well. Based on these algorithms, we develop an automate tool, FCA Wizard, for concept analysis and concept hierarchy. We also present FCA Wizard based applications in medical domain.

Performance Enhancement of Biofuel Cell by Surface Modification of Glucose Oxidase using Ferrocene Carboxylic acid (페로신카르복시산을 이용한 글루코스 산화효소의 표면개질에 의한 바이오 연료전지 성능향상)

  • JI, JUNGYEON;CHRISTWARDANA, MARCELINUS;CHUNG, YONGJIN;KWON, YONGCHAI
    • Transactions of the Korean hydrogen and new energy society
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    • v.27 no.5
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    • pp.526-532
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    • 2016
  • In this study, we synthesized a mediator immobilized biocatalyst([FCA/GOx]/PEI/CNT) by surface modification using ferrocene carboxylic acid(FCA), and evaluated its performance as anode catalyst for biofuel cell. Through the application of FCA on glucose oxidase (GOx), the free amine groups on the lysine residue of GOx surface reacted with carboxylic acid of FCA and make amide bond between GOx and FCA. As the result of that, the electron transfer of catalyst was increased up to 1.91 times($0.468mA{\cdot}cm^{-2}$) than the catalyst without surface modification (GOx/PEI/CNT), and high maxium power density of $1.79mA{\cdot}cm^{-2}$ was gained.

An FCA-mediated epigenetic route towards thermal adaptation of autotrophic development in plants

  • Lee, Hyo-Jun;Ha, Jun-Ho;Park, Chung-Mo
    • BMB Reports
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    • v.50 no.7
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    • pp.343-344
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    • 2017
  • Plants are able to recognize even small changes in surrounding temperatures to optimize their growth and development. At warm temperatures, plants exhibit diverse architectural adjustments, including hypocotyl and petiole elongation, leaf hyponasty, and reduced stomatal density. However, it was previously unknown how such warm temperatures affected the early stages of seedling development. In our recent study, we demonstrated that the RNA-binding protein, FCA, is critical for sustaining chlorophyll biosynthesis during early seedling development, which is a prerequisite for autotrophic transition at warm temperatures. FCA plays a dual role in this thermal response. It inhibits the rapid degradation of protochlorophyllide oxidoreductases (PORs) that mediate chlorophyll biosynthesis. In addition, it induces the expression of POR genes at the chromatin level, which contributes to maintaining functional enzyme levels. Our findings provide molecular basis for the thermal adaptation of chlorophyll biosynthesis during the early stages of seedling development in nature.

Deep Learning-based Extraction of Auger and FCA Coefficients in 850 nm GaAs/AlGaAs Laser Diodes

  • Jung-Tack Yang;Hyewon Han;Woo-Young Choi
    • Current Optics and Photonics
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    • v.8 no.1
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    • pp.80-85
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    • 2024
  • Numerical values of the Auger coefficient and the free carrier absorption (FCA) coefficient are extracted by applying deep neural networks (DNNs) to the L-I characteristics of 850 nm GaAs/AlGaAs laser diodes. Two elemental DNNs are used to extract each coefficient sequentially. The fidelity of the extracted values is established through meticulous correlation of L-I characteristics bridging the realms of simulations and measurements. The methodology presented in this paper offers a way to accurately extract the Auger and FCA coefficients, which were traditionally treated as fitting parameters. It is anticipated that this approach will be applicable to other types of opto-electronic devices as well.

Efficiency of Graph for the Remodularization of Multi-Level Software Architectures

  • Lala Madiha HAKIK
    • International Journal of Computer Science & Network Security
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    • v.24 no.5
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    • pp.33-39
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    • 2024
  • In a previous study we proceeded to the remodularization architecture based on classes and packages using the Formal Concept Analysis (FCA)[13] [14] [30]. we then got two possible remodularized architectures and we explored the issue of redistributing classes of a package to other packages, we used an approach based on Oriented Graph to determine the packages that receive the redistributed classes and we evaluated the quality of a remodularized software architecture by metrics [31] [28] [29]. In this paper, we will address the issue of the efficiency of the Oriented Graph in the remodularization of software architectures compared to the Formal Concept Analysis FCA method. The formal method of FCA concept is not popularized among scientists as opposed to the use of the labeled directed graph. It is for this reason that our directed graph approach is more effective in its simplicity and popularity.