• 농업과학연구
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• 제4권1호
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• pp.34-42
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• 1977

옥수수의 우수 품종선발을 위하여 3가지 선발지수를 계산하여 이들 지수의 효과를 비교하였든바 1. William의 기초지수가 가장 계산하기도 쉬웠고 우수 품종선발에서도 효과적이었다. 2. Pesek과 Baker가 제창한 선발지수법은 관여형질의 유전분산 및 공분산을 계산하는데 까다로웠고 또한 공시품종수가 적든가 시험연수나 장소가 많지 않은 경우에는 이들 유전분산 및 공분산이 낮았으며 본 실험에 있어서는 큰 효과가 없었다. 3. 퍼듀 대학의 지수계산법은 계산도 용이하여 사용하기에 편리하였지만 다만 관여형질 등에 대한 중요도를 모두 동일시 하는데 큰 결점이 있었다. 4. 관여형질들을 경제적 가치로 환산하는데 다음과 같은 공식을 이용하였다. 1) 수분함량 : $(Y-15.5){\times}$0.0065{\times}$분셀/에카 여기서 Y는 수확시 수분함량이었고 $0.0065는 1붓셀의 옥수수에서 1%의 수분을 건조시키는데 요하는 경비였다. 2) 뿌리 및 줄기도복 : 도복율(%)${\times}$붓셀당가격${\div}$50${\div}$전체시험구의 평균수량.

• 한국인구학
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• 제19권2호
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• pp.47-76
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• 1996

이 논문은 인구자질정책을 전개하는 데 필요한 기초적인 정보를 제공하기 위하여 실시된 임신추적조사의 결과이다. 경기도 가평군 전지역을 대상으로 1993년 11월 3일부터 1995년 12월 31일까지 유배우 여성이 경험한 모든 임신을 추적조사하여 임신경과와 그 결과를 관찰하였다. 조사기간중 782건의 임신이 관찰되었는데, 이중 642건은 최종 임신종결 형태가 확인되었으며 140건은 전출 및 조사종료에 따라 관찰이 중단되었다. 본 연구에서는 임신추적조사 자료로 태생기 생명표를 작성하여 그 생명현상을 분석하였다. 태생기 생명표에 따른 임신종결확률은 출생률 53.5%, 태아사망률 14.5%, 인공유산율 32.0%로 전임신기간을 통해서 46.5%의 임신손모가 있었으며, 태아주령에 따른 임신종결확률의 곡선모양은 인공유산율과 태아사망률 모두 L형을 나타내었다. 한편 인위적으로 임신을 중단시키는 인공유산을 제외했을 경우의 태아사망확률은 21.9%였다. 본 연구의 결과에 따르면 임신 초기에 태아사망이나 인공유산과 같은 임신손모에 의해 태생기의 생명이 상당히 손실되고 있는 것으로 나타났다. 따라서 임신손모를 방지하기 위한 대책이 이루어져야 할 것이다.

• Restorative Dentistry and Endodontics
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• 제28권5호
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• pp.402-408
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• 2003

This study was done to present a criterion in selection of the most proper light sources and materials by measuring metamerism index(MI) of the light curing composite resins with spectrocolorimeter. Metamerism is defined when two objects appear to be the same color in one illuminant but different in another. This is due to the fact that they have different spectral curves that fail to match under the second illuminant. In this study, A1 & A3 shade of five light curing composite resins (Esthet-X, Filteck Z250, Filteck A110. Charisma. Vitalescence) were chosen based on Vita shade. Five samples were made for shade of each product with Teflon mold (diameter: 15mm, thickness: 2mm). Metamerism index of each samples on a Barium sulfate plate($L^{*}=96.54,{\;}a^{*}=0.19,{\;}b^{*}=0.01$) prepared for sample fixation were measured with spectrocolorimeter(Miniscan XE plus. Model 4000s. Hunter Lab. USA) by applying standard light source D^{65}, C. Fcw, TL84 and A. Standardization was done with reference standard(X=80.8, Y=85.7, Z=90.8) and light trap. The results were as follows. 1. Different resins with same Vita shade showed recognizable color difference (${\delta}E^{*}>2$). 2. All composites had MI below accepted value 0.5 between standard illuminant(D$_{65}$, C, & A) and below 1.5 under fluorescent condition (Fcw & TL84). 3. MI value between $D^{65}$ and A showed higher value than MI value between other source of light(p<0.01). 4. All resins except Z250 showed MI value that A3 is higher than A1 between $D^{65}$ and A(p<0.05).except Z250 showed MI value that A3 is higher than A1 between $D^{65}$ and A(p<0.05).

• 한국토양비료학회지
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• 제33권5호
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• pp.340-346
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• 2000

본 실험은 질소 시비 수준 0, 80, 160, $240kg\;ha^{-1}$에 따른 율무 1호 품종의 생육 특성, 조곡 수량, 질소축적 및 수확 후 토양의 화학성분 변화를 조사하였다. 질소시비 수준이 증가될수록 출수, 개화기는 단축되었으나 개화기부터 수확기까지 소요되는 기간은 증가되어 파종에서 수확기까지 소요되는 기간은 0-5 일 증가되었다. 질소시비 수준이 증가할수록 간장, 주분얼경의 수, 착립부위고는 유의한 증가를 보였다 (P<0.05). 주간절수, 주간직경, 착립부위장은 유의한 차이가 없었다. 주간의 소수지경수, 주간의 착립절간은 유의한 증가가 있었으나 $80kg\;ha^{-1}$ 이상에서는 큰 차이가 없었다 (P<0.05) 조명나방 피해는 질소 $240kg\;ha^{-1}$ 처리구에서 30%로 높아 수량감소의 요인으로 작용하였다. 수량구성요소는 질소시비량과 비례하여 양호해지는 경향이었으나 주당립수는 질소시비량 $160kg\;ha^{-1}$ 구에서 가장 많아 조곡 수량이 $3,410kg\;ha^{-1}$로 최고 질소 시비수준인 $240kg\;ha^{-1}$구에 비해 $140kg\;ha^{-1}$ 많았다. 질소사용효율은 질소시비량이 증가할수록 감소하였다. 실험후 토양중 총 질소함량은 실험전에 비해 질소 0, $80kg\;ha^{-1}$ 구에서는 낮았으며 질소 160, $240kg\;ha^{-1}$ 구에서는 높았다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2009년도 제38회 동계학술대회 초록집
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• pp.44-45
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• 2010

We are currently conducting studies on culturing and biocompatibility assessment of various cells such as neural stem cells and induced pluripotent stem cells(IPS cells) on carbon nanotube (CNT), on nerve regeneration electrodes, and on silicon wafers with a focus on developing nerve integrated CNT based bio devices for interfacing with living organisms, in order to develop brain-machine interfaces (BMI). In addition, we are carried out the chemical modification of carbon nanotube (mainly SWCNTs)-based bio-nanosensors by the plasma ion irradiation (plasma activation) method, and provide a characteristic evaluation of a bio-nanosensor using bovine serum albumin (BSA)/anti-BSA binding and oligonucleotide hybridization. On the other hand, the researches in the case of "novel plasma" have been widely conducted in the fields of chemistry, solid physics, and nanomaterial science. From the above-mentioned background, we are conducting basic experiments on direct irradiation of body tissues and cells using a micro-spot atmospheric pressure plasma source. The device is a coaxial structure having a tungsten wire installed inside a glass capillary, and a grounded ring electrode wrapped on the outside. The conditions of plasma generation are as follows: applied voltage: 5-9 kV, frequency: 1-3 kHz, helium (He) gas flow: 1-1.5 L/min, and plasma irradiation time: 1-300 sec. The experiment was conducted by preparing a culture medium containing mouse fibroblasts (NIH3T3) on a culture dish. A culture dish irradiated with plasma was introduced into a $CO_2$-incubator. The small animals used in the experiment involving plasma irradiation into living tissue were rat, rabbit, and pick and are deeply anesthetized with the gas anesthesia. According to the dependency of cell numbers against the plasma irradiation time, when only He gas was flowed, the growth of cells was inhibited as the floatation of cells caused by gas agitation inside the culture was promoted. On the other hand, there was no floatation of cells and healthy growth was observed when plasma was irradiated. Furthermore, in an experiment testing the effects of plasma irradiation on rats that were artificially given burn wounds, no evidence of electric shock injuries was found in the irradiated areas. In fact, the observed evidence of healing and improvements of the burn wounds suggested the presence of healing effects due to the growth factors in the tissues. Therefore, it appears that the interaction due to ion/radicalcollisions causes a substantial effect on the proliferation of growth factors such as epidermal growth factor (EGF), nerve growth factor (NGF), and transforming growth factor (TGF) that are present in the cells.

• Molecules and Cells
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• 제38권1호
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• pp.1-13
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• 2015

Recent technical developments have transformed how neuroscientists can probe brain function. What was once thought to be difficult and perhaps impossible, stimulating a single set of long range inputs among many, is now relatively straight-forward using optogenetic approaches. This has provided an avalanche of data demonstrating causal roles for circuits in a variety of behaviors. However, despite the critical role that neuropeptide signaling plays in the regulation of behavior and physiology of the brain, there have been remarkably few studies demonstrating how peptide release is causally linked to behaviors. This is likely due to both the different time scale by which peptides act on and the modulatory nature of their actions. For example, while glutamate release can effectively transmit information between synapses in milliseconds, peptide release is potentially slower [See the excellent review by Van Den Pol on the time scales and mechanisms of release (van den Pol, 2012)] and it can only tune the existing signals via modulation. And while there have been some studies exploring mechanisms of release, it is still not as clearly known what is required for efficient peptide release. Furthermore, this analysis could be complicated by the fact that there are multiple peptides released, some of which may act in contrast. Despite these limitations, there are a number of groups making progress in this area. The goal of this review is to explore the role of peptide signaling in one specific structure, the bed nucleus of the stria terminalis, that has proven to be a fertile ground for peptide action.

• 실내환경 및 냄새 학회지
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• 제17권4호
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• pp.355-361
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• 2018

Mold grows more easily when humidity is higher in indoor spaces, and as such is found more often on wetted areas in housing such as walls, toilets, kitchens, and poorly managed spaces. However, there have been few studies that have specifically assessed the level of mold in the indoor spaces of water-damaged housing in the Republic of Korea. We investigated the levels of airborne mold according to the characteristics of water damage types and explored the correlation between the distribution of mold genera and the characteristics of households. Samplings were performed from January 2016 to June 2018 in 97 housing units with water leakage or condensation, or a history of flooding, and in 61 general housing units in the metropolitan and Busan area, respectively. Airborne mold was collected on MEA (Malt extract agar) at flow rate of 100 L/min for 1 min. After collection, the samples were incubated at $25^{\circ}C$ for 120 hours. The cultured samples were counted and corrected using a positive hole conversion table. The samples were then analyzed by single colony culture, DNA extraction, gene amplification, and sequencing. By type of housing, concentrations of airborne mold were highest in flooded housing, followed by water-leaked or highly condensed housings, and then general housing. In more than 50% of water-damaged housing, the level of airborne mold exceeded the guideline of Korea's Ministry of Environment ($500CFU/m^3$). Of particular concern was the fact that the I/O ratio of water-damaged housing was greater than 1, which could indicate that mold damage may occur indoors. The distribution patterns of the fungal species were as follows: Penicillium spp., Cladosporium spp. (14%), Aspergillus spp. (13%) and Alternaria spp. (3%), but significant differences of their levels in indoor spaces were not found. Our findings indicate that high levels of mold damage were found in housing with water damage, and Aspergillus flavus and Penicillium brevicompactum were more dominant in housing with high water activity. Comprehensive management of flooded or water-damaged housing is necessary to reduce fungal exposure.

• 한국산학기술학회논문지
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• 제22권2호
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• pp.362-367
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• 2021

본 연구는 방한 중국관광객에 대해 브랜드 인지도와 지각된 가격공정성이 매스티지 구매의도에 미치는 영향을 확인하고, 한·중 양국의 유명 광고모델이 이 관계에 어떻게 영향을 미치는 지 연구하였다. 명품의 이미지와 합리적인 가격대라는 매스티지의 특성에 따라 매스티지 원산지와 일치하는 국적(한국)모델과 중국관광객의 자국(중국)모델의 영향을 해석수준이론을 통하여 살펴보고자 하였다. 가설검증을 위해 2(브랜드인지도 고·저)×2(가격공정성)×2(광고모델 국적) 집단 간 실험설계를 실시하였다. 연구결과, 브랜드 인지도와 지각된 가격공정성은 각각 매스티지 구매의도에 정의 영향을 미쳤으며, 광고모델 국적의 조절효과도 유의미하였다. 광고모델이 한국 국적일 경우 브랜드인지도와 지각된 가격 공정성의 구매의도에 대한 영향이 중국 국적의 광고모델의 경우보다 더 크게 나타났다. 본 논문은 매스티지 브랜드는 중국 관광객에게 심리적 거리감이 있더라도 브랜드이미지에 맞는 한류 모델의 영향이 중국 모델보다 더 크다는 것을 보여준 연구로서 시사점이 있다고 하겠다.

• 한국해양바이오학회지
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• 제13권2호
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• pp.76-85
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• 2021

Crassostrea gigas were fermented using L. brevis BJ20 to prepare fermented oyster extract (FO). The participants of this study were randomly assigned to FO and placebo (CON) groups. The FO group was given 1.0 g of FO supplementation and the CON group was given sucrose each day for eight weeks. The effects of FO supplementation on body composition, muscula r strength, and blood factors associated with muscle growth were assessed. The FO supplement was enriched with arginine (6,183.3 mg), phenylalanine (217.9 mg), leucine (122.6 mg), isoleucine (59.8 mg), valine (16.4 mg), and γ-amino butyric acid (GABA, 1,053.7 mg). The total fat was significantly decreased in the FO group compared with the CON group (p < 0.05). 60D/S Ext.T/Wo rk and 60D/S Flex.T/Work concomitantly with 60D/S Flex.PeakTQ/BW were significantly increase d by FO treatment compared to CON group (p < 0.05). However, posture stability was not significa ntly different between the groups. The levels of angiotensin-converting enzyme were significantly decreased within the FO group (p < 0.05). The FO group showed significantly decreased levels of tumor necrosis factor-α and increased levels of human growth hormone compared with the CON group (p < 0.01). The levels of insulin-like growth factor-1 increased (p < 0.01) in the FO group while that of creatine kinase and triglyceride decreased significantly compared with the CON group (p < 0.05). These results demonstrated that FO supplementation is effective in preventing sarcopenic obesity and maintaining and strengthening muscular function in elderly wom en. Hence, FO supplements can be used as functional ingredients for these benefits.

• 생명과학회지
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• 제33권4호
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• pp.349-356
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• 2023

만성 염증성 관절염 질환인 통풍은 고요산혈증을 특징으로 하며 NLRP3 inflammasome의 활성화에 따른 IL-1β와 같은 염증성 cytokine 방출과 연관된 MSU에 대한 염증 반응에 의해 유발될 수 있다. 마늘에 함유된 황 함유 화합물은 다양한 질병에 대한 잠재적인 유익한 약리학적 효능을 가지지만, NLRP3 inflammasome 활성화와 연관된 통풍 억제에 대한 효능은 현재까지 입증되지 않았다. 본 연구에서는 대표적인 마늘 유래 황화합물인 DADS와 DATS가 MSU에 의한 NLRP3 inflammasome 활성을 억제할 수 있는지를 조사하였다. 본 연구의 결과에 의하면, 비세포 독성 조건에서 DADS와 DATS는 LPS가 전처리된 RAW 264.7 대식세포에서 MSU에 대한 반응으로 증가된 NO의 생성과 IL-1β 유리를 유의적으로 차단하였다. DADS와 DATS는 또한 증가된 NLRP3, ASC, caspase-1 p20 및 IL-1β의 발현을 감소시켰으며, 이는 MSU로 유도된 LRP3 inflammasome 활성화가 DADS와 DATS에 의해 억제되었음을 의미한다. 아울러, DADS와 DATS는 NLRP3 inflammasome 활성화에 상위 신호로 작용하는 산화적 스트레스를 차단했으며 ROS 생성을 제거한다는 사실에서 입증되었다. 결론적으로, 본 연구의 결과는 DADS와 DATS가 ROS/NLRP3 경로를 억제하여 inflammasome 활성화를 차단함으로서 NLRP3 의존성 통풍성 관절염 치료를 위한 잠재력이 우수함을 의미한다.