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Analysis on the Antioxidant Activity of Catechin Concentrations and Green Tea Extract Powder (녹차 분말과 카테킨의 농도에 따른 항산화력 비교 분석)

  • Choi Kyung-Min;Yun Young-Gab;Jiang Jing-Hua;Oh Sung-Su;Yang Hwan-Deok;Kim Hyoung-Jun;Park Jin-Young;Jeon Byung-Hun;Kim Suk-Il;Park Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.6
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    • pp.1580-1584
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    • 2005
  • Antioxidative activities of catechin from green tea extracts were examined by the methods of 1,1-Diphenyl-2-picrylhydrazyl (DPPH) electron donating ability, hydroxy scavenging activity and the inhibitory effect on xanthine oxidase activity. The resulted demonstrated the fact that Catechin one (containing Green tea extracts plus catechin 51%) of green tea extracts product showed at 65.5% in electron donating activity on the DPPH. The electron donating ability on the DPPH of Catechin one was increased to 10% than purified catechin. Catechin one showed the activity at 64.5% in scavenging activity using hydroxy radical method. To the Catechin one provided to increase the hydroxy scavenging activity up to 3 fold. Inhibitory effects of the catechin one measured with xanthine oxidase method was 6.5%. Although the antioxidative activity of catechin (98% purified) was lower than that of Catechin one (containing Green tea extracts plus catechin 51%) in same catechin concentrations ($5{\mu}g$, respectively). Therefore, we may suggest that Catechin one can be used as a functional food additive possessing the potent antioxidative activity.

Hilbert's Program as Research Program (연구 프로그램으로서의 힐버트 계획)

  • Cheong, Kye-Seop
    • Journal for History of Mathematics
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    • v.24 no.3
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    • pp.37-58
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    • 2011
  • The development of recent Mathematical Logic is mostly originated in Hilbert's Proof Theory. The purpose of the plan so called Hilbert's Program lies in the formalization of mathematics by formal axiomatic method, rescuing classical mathematics by means of verifying completeness and consistency of the formal system and solidifying the foundations of mathematics. In 1931, the completeness encounters crisis by the existence of undecidable proposition through the 1st Theorem of G?del, and the establishment of consistency faces a risk of invalidation by the 2nd Theorem. However, relative of partial realization of Hilbert's Program still exists as a fruitful research program. We have tried to bring into relief through Curry-Howard Correspondence the fact that Hilbert's program serves as source of power for the growth of mathematical constructivism today. That proof in natural deduction is in truth equivalent to computer program has allowed the formalization of mathematics to be seen in new light. In other words, Hilbert's program conforms best to the concept of algorithm, the central idea in computer science.

Debates on the New National Elementary Mathematics Curriculum Content (초등학교 수학과 교육과정의 내용 선정과 조직에서의 쟁점 - 2006년 개정 교육과정을 중심으로 -)

  • Han, Dae-Hee
    • Journal of Elementary Mathematics Education in Korea
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    • v.14 no.3
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    • pp.633-658
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    • 2010
  • This study aimed to analyze the debate on the Elementary School Mathematics Contents in the new National Elementary Mathematics Curriculum developed in 2006. With this, the feature of the new National Mathematics Curriculum compared with the past 7th National Elementary Mathematics Curriculum was investigated. And the drafts on developing the new National Elementary Mathematics Curriculum were investigated as well. Three main controversies were identified. The first controversy was related to the item which had been dealt in middle school curriculum and moved to elementary school in the new National Mathematics Curriculum (e.g. equations, direct proportion and inverse proportion). The second one was related to the order of teaching fraction. The third one was related to the fact that problem solving became one of the five domains in Elementary School Mathematics Curriculum. Those controversies came from a basic belief on the ranges and depths of elementary school mathematics, didactical point of view, or thoughts on what should the content in the National Mathematics Curriculum be. The issues and suggestions that were discussed in this paper might serve to improve the National Mathematics Curriculum.

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AC loss dependency on the arrangement of the HTS wires in the current limiting module for SFCL (초전도 한류모듈 내 고온초전도 선재 배치에 따른 교류손실 변화)

  • Kim, W.S.;Yang, S.E.;Lee, J.Y.;Kim, H.;Yu, S.D.;Hyun, O.B.;Kim, H.R.
    • Progress in Superconductivity and Cryogenics
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    • v.14 no.3
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    • pp.9-12
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    • 2012
  • Usually, the AC loss from the superconducting element of an SFCL due to the load current is very small because it is composed of the combination of bifilar windings with very small reactance. Although the AC loss is small enough, we should be albe to predict for the design and control of the cryogenic system. In fact, an SFCL for the transmission voltage class may not generate ignorable AC loss because of the inevitable space between the HTS wires for the high voltage insulation and cryogenic efficiency. To measure the AC loss dependency on the space between the 2G HTS wires with the width of 4.4 mm, we prepared an experimental setup which could adjust the distance between the wires. We used two 500-mm length HTS wires in parallel and applied the current in the opposite direction for each wire to simulate a part of a current limiting module for a high voltage SFCL. We also put two couples of voltage taps at the ends of each wire and a cancel coil in the voltage measurement circuit to compensate the reactive component from the voltage taps. In this condition, we varied the distance between the wires to investigate the change of the transport current loss. A similar experimental study with HTS wire with the width of 12 mm is now in progress.

A Clinical Consideration of Necrotizing Lymphadenitis (괴사성 림프절염에 대한 임상적 고찰)

  • 유명종;조우령;김학선;이재동;김명구
    • Korean Journal of Bronchoesophagology
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    • v.6 no.2
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    • pp.164-171
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    • 2000
  • Background and Objectives: Necrotizing lymphadenitis or Kikuchi's disease is characterized by cervical lymphadenopathy of unknown etiology with unique histologic findings in young female patients. The importance of this disease lies in the fact that it can be easily misdiagnosed as malignant lymphoma, hence, clinicians need to aware of this disease entity. The purpose of this study is to report the clinicopathologic findings, radiographic findings, and many laboratory tests in order to contribute to the diagnosis and treatment of necrotizing lymphadenitis. Materials and Methods: We evaluated 31 patients, who were diagnosed as necrotizing lymphadenitis by excisional biopsy or fine needle aspiration cytology or ultrasound guided 18G cutting needle biopsy, retrospectively. Result : The median age was 24.8 years (range 12 to 43 years) and the male to female ratio was 1 : 2.4(9:22), with 14 females (45.1%) under 30 years. The common chief complaints were neck mass, easy fatigue and fever. Lymph node enlargement was limited to the cervical area in most cases (28cases : 90.3%). The involved lymph nodes were usually multiple (20cases : 64.5%), unilateral (26cases 83.9%) and small sized. Leukopenia (19cases : 61.3%) and elevation of ESR (18cases : 58.1%) appeared most frequently in the abnormal laboratory data. These symptoms will be gone spontaneoulsy without any specific treatment in several weeks or months. Conclusion : We should consider open biopsy or fine needle aspiration cytology or ultrasound guided cutting needle biopsy with lymph node in patients who have cervical lymphadenopathy with easy fatigue and fever, especially young women to exclude other conditions such as malignant lymphoma and tuberculosis, etc.

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A Study on the Establishment of Basic Design Concept for Semi-Submersibles (해저자원(海底資源) 개발용(開發用) Semi-Submersible 설계기준(設計基準)의 정립(定立)을 위한 연구(硏究))

  • J.E.,Park;Z.G.,Kim;J.H.,Hwang;S.J.,Yim;H.S.,Choi
    • Bulletin of the Society of Naval Architects of Korea
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    • v.20 no.2
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    • pp.1-20
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    • 1983
  • In this paper design criteria for semi-submersibles, effective at the stage of basic design, are reviewed first generally. Thereafter an extensive study is focussed on essential problematic areas such as design load, heaving motion, overall structural analysis and welding technique. The necessity for this kind of research is apparent in the light of the fact that ocean exploration and exploitation becomes extended to deeper ocean and that semi-submersibles are the most favorite unit for operation under this environment. In some sense principles in naval architecture are indeed applicable to the design of semi-submersible. However, because of the difference in geometry between ships and semi-submersibles, there are significant deviations in design method. A thorough discussion is made on particular behaviours of a semi-submersible in stability, wave load, motion characteristics and structural responses. Then some calculation-procedures and design guidelines are tentatively proposed. A numerical calculation for a semi-submersible Sedco 708 is exemplified for better understanding of the concept. The structure has 4 main and another 4 secondary stabilizing columns with catamaran-type lower hull. In this example design condition is supposed to be 28m wave height, 90 knots wind speed for survival condition and seastate 6 for operational condition in water of 100m depth. The numerical result implies that the actual design of this model can be assessed close to optimum. Further intensive research is strongly required in the subject fields of dynamic stability, rational evaluation of wave load statistical basis for fatigue life judgement.

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A Case Of Symptoms and Quality Of Life Changes in Stage IV Gallbladder Cancer with Hematogenous Lung Metastasis by Sasang Constitutional Medicine (폐전이된 담낭암 환자를 사상의학적 관리를 통해 제반 증상과 삶의 질을 개선시킨 1례)

  • Seo, Young-Kwang;Kim, Eun-Hee;Kim, Dal-Lae;Ko, Byung-Hee;Cheon, Seong-Ha;Eo, Wan-Kyu;Kim, Se-Hyun;Choi, Won-Cheol;Lee, Soo-Kyung
    • Journal of Sasang Constitutional Medicine
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    • v.19 no.2
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    • pp.187-194
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    • 2007
  • 1. Objectives The incidence of Gallbladder(GB) cancer is increasing through out the world. And the death rate of GB cancer is highest compared with other kinds of cancers. We treated Stage IV GB canter with lung metastasised patient with Sasang constitutional medicine. 2. Methods We fellowed up the changes of Symptoms and QOL. 3. Results The symptoms and quality of lift(QOL) of Stage IV GB cancer with both lung metastasis patient are improved markedly by Sasang constitutional medicine. 4. Conclusions The symptoms of GB cancer with both Lung mets were effectively managed through the constitutional treatment So we report the healing process and result of this patient in this study.

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Selection of Capillary Tubes for HCFC-22 Alternative Fluids (HCFC-22 대체냉매의 모세관 선정)

  • Jung, D.S.;Kim, C.B.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.7 no.3
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    • pp.435-449
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    • 1995
  • In this paper, pressure drop through a capillary tube is modeled to determine the length of a capillary tube for a given set of conditions. HCFC-22 and its alternatives, HFC-134a, R407B, and R410A are used as working fluids. The conditions on which the model is tested are as follows : condensing temperature; 40.0, 45.0, 50.0, $55.0^{\circ}C$, degree of subcooling;0.0, 2.5, $5.0^{\circ}C$, capillary tube exit condition;choked flow, capillary tube diameter;1.2~2.4mm, mass flow rate;5.0~50.0g/sec. The results justify the use of Stoecker's model which yields the results very close to the values in ASHRAE handbook. While McAdams' method yields much better results than Duckler's in calculating the viscosity of the fluid in 2-phase, the friction factor suggested by Stoecker seems to be the best for capillary tubes of large diameter used in residential air conditioners. For each refrigerant, 372 data with various variables are calculated by the model. The results show that capillary tube length varies very uniformly with changes in condensing temperature and degree of subcooling. Based on this fact, regression analysis is performed to determine the dependence of mass flow rate on the length and diameter of a capillary tube, condensing temperature, and degree of subcooling. Thus determined correlation yields a mean deviation of 2.36% for 1,488 data, showing an excellent agreement.

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Sphingolipid Metabolic Changes during Chiral C2-Ceramides Induced Apoptosis in Human Leukemia Cells

  • Baek, Mi-Young;Yoo, Hwan-Soo;Kazuyasu Nakaya;Moon, Dong-Cheul;Lee, Yong-Moon
    • Archives of Pharmacal Research
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    • v.24 no.2
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    • pp.144-149
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    • 2001
  • N-acetylsphingosine (C2-ceramide) is a synthetic water-soluble ceramide mimicking the activity of natural ceramides. By fixing chiral conformation on carbon numbers 2 and 3 in the ceramide structure, four chiral C2-ceramides naming d-erythro-, I-erythro-, d-threo-and 1-three C2-ceramide were synthesized. We have investigated the chiral effects of these C2-ceramides on the sphingolipid metabolism, particularly on both the sphingolipid bio- synthetic pathway and on the degradation pathway. In both HL-60 and U937 cells, the chiral C2-ceramide ($10{\mu}\textrm{m}$) showed sphingosine accumulation monitored fluoromatrically by a high performance liquid chromatographic separation of the sphingoid bases. Most importantly, in HL-60 cells, l-erythro C2-ceramide induced a 50 fold increase in sphingosine as compared to the control, while l-threo C2-ceramide exhibited a minimal 7-fold in-crease. In contrast, sphinganine, another sphingoid base, showed less accumulation by any chiral C2-ceramide tested under the same conditions. These results suggested that chiral C2-ceramide primarilyacts on the sphingolipid degradation pathway rather than on the sphingolipid biosynthetic route. The strong $C_0/G_1$ phase arrest in the cell cycle by treatment of I-erythro C2-ceramide indicates that the blockade of the sphingolipid degradation pathway might be concomitantly involved in the dysfunction of the cell cycle. On the other hand, the fact that all chiral C2-ceramides tested failed to inhibit the activity of sphingosine kinase acting on the removal of sphingosine by producing sphingosine-1 -phosphate demonstrates that chiral C2- ceramides may increase sphingosine by activating various ceramidases by which natural ceramides are divided into sphingosine and free fatty acids. However, the precise steps involved in this interaction are still unknown.

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Growth Characteristics and Changes of Pigment Content of Purple Sweet Potato during Growth (자색고구마의 생육특성 및 색소함량의 변화)

  • Kim, Seon-Jae;Rhim, Jong-Whan;Lee, Lan-Sook;Lee, Joon-Seol;Jeong, Byeong-Choon
    • Korean Journal of Food Science and Technology
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    • v.28 no.6
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    • pp.1180-1183
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    • 1996
  • Growth characteristics and changes of pigment content of purple sweet potato (PSP) during growth were investigated. Vine length of PSP was increased to the maximum length of 130 cm after 100 days of growth. Numbers of branches and nodes were increased to the maximum of 21and 550, respectively, after 120 days of growth. Vine weight was also increased to the maximum of 4,384 kg/10a after 120 days of growth, while the weight of marketable root was increased continuously to the end of the growth period of 150 days to reach the production of 1,875 kg/10a. Uniquely considerable amount of anthocyanin pigment has been developed in both skin and flesh of young roots harvested after 40 days of growth. The pigment content was increased slowly until 140 days of growth then decreased. This fact indicates that the best time for harvesting of PSP is 140 days after planting.

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