• Title/Summary/Keyword: FACT-G

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Evaluation of 8-week body weight control program including sea tangle (Laminaria japonica) supplementation in Korean female college students

  • You, Jeong-Soon;Sung, Min-Jung;Chang, Kyung-Ja
    • Nutrition Research and Practice
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    • v.3 no.4
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    • pp.307-314
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    • 2009
  • This study was conducted to evaluate the effects of a body weight control program with supplementation of sea tangle (20 g/day) on 22 female college students. The contents of the program for 8 weeks contained diet therapy, exercise and behavioral modification through nutrition education. Body composition, dietary habit scores, serum lipid profiles, daily nutrient intakes and the quality of life were assessed at the beginning and at the end of the program. Average age of subjects and height were 20.8 years and 161.9 cm, respectively. After 8 weeks, there were significant reductions in body weight, body fat mass, percent body fat, waist-hip ratio and BMI. The dietary habit score such as a balanced diet, regularity of mealtime, overeating, eating while watching TV or using the computer and eating salty food were increased significantly. Serum lipid levels such as total cholesterol level, LDL-cholesterol level and triglyceride level were decreased but not significantly. There were decreases in intake of energy, protein and fat and increases in intakes of dietary fiber, folic acid, calcium and potassium from the beginning to the end of the program. There were significant improvements on subcomponents of quality of life; physical functioning, general-health and vitality. The limitation of this study was the fact that there was no control group, but an overall evaluation suggests the 8-week body weight control program consisting of diet therapy, exercise and behavioral modification with supplementation of sea tangle would be helpful to improve the body composition, dietary habits, daily nutrient intakes and quality of life in Korean female college students.

Changes in the Physiochemical Characteristics of Artificial Soil after Rooftop Planting (옥상녹화 후 인공토양의 이화학적 특성 변화)

  • 안원용;김동엽
    • Journal of the Korean Institute of Landscape Architecture
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    • v.28 no.6
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    • pp.77-83
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    • 2001
  • The purpose of this study is to provide the fundamental material and information for the plant maintenance after rooftop planting through physiochemical characteristics. The characteristics of artificial soils after rooftop planting from 1993 to 1999 was investigated. Fourteen investigation areas were selected from 4 cities(2 areas selected by each year). The analysis of the circumstances of the areas, the physical characteristics, and the chemical characteristics of the soil were conducted. The artificial soil pH ranged 5.26∼7.40 showing that after construction the soil pH tended to decrease. The soil bulk density of the site was lowest in 1999, 0.15g/㎤, and used to increase toward 1993. We found the fact that the soil bulk density increased gradually after rooftop application . The coefficients of permeability of the soils range from 0.016 to 0.052 cm/sec, which seemed to be in good permeability level. The artificial soils had relatively high water moisture capacity of 62.69∼71.36%. The soil organic matter content of the artificial soils ranged from 0.43 to 1.34%. The exchangeable caution concentration in the artificial soil ranged, Na, 2.36∼4.71mg·{TEX}$kg^{-1}${/TEX}, Mg 0.88∼2.84mg·{TEX}$kg^{-1}${/TEX},K 2.97∼9.61 mg·{TEX}$kg^{-1}${/TEX}, and Ca 9.39∼28.23 mg·{TEX}$kg^{-1}${/TEX}. The amount of total N ranged from 0.003 to 0.286% in study sites. Soil chemical properties varied year to year and showed little tend. The research results showed that some characteristics of the artificial soil were changed after rooftop planting, i.e., soil pH and soil bulk density. Soil bulk density had a negative relationship with the coefficient of permeability, showing that the drainage condition might be limited after some period. This study suggests that a diversity of the research in the changes of the plant growth basis on the areas after construction.

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Effects of Coordinative Locomotor Training Program on Low Extremity Strength, Balance and Quality of Life in Patients with Cancer: Single-Subject Design (CLT프로그램이 암 환자의 하지 근력, 균형 및 삶의 질에 미치는 영향: 단일사례설계)

  • Hwang, Jeong-Keun;Park, Jang-Seong;Lim, Jae-Heon
    • Journal of the Korean Society of Physical Medicine
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    • v.12 no.4
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    • pp.47-59
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    • 2017
  • PURPOSE: This study was to identify the effect of a coordinative locomotor training (CLT) programs on lower extremity strength, balance, and quality of life of a cancer patients. METHODS: Subjects were instructed in CLT programs. The CLT programs consisted of sprinter and skater pattern movements performed for 30 minute three day per week for two weeks. CLT programs performed the arms and legs alternately and step up the steps on the stairs. The timed sit to stand test (TSTS) and one leg standing test (OLST) were used to test lower extremity strength. The star excursion balance test (SEBT) was used to measure balance; and the functional assessment of cancer therapy - general (FACT-G) for measuring the quality of life throughout the sessions. RESULTS: Participants showed enhanced strength compared to first baseline, as measured by TSTS (14.58%). Balance was improved compared to the first baseline as measure by OLST with open eyes (30.3%), OLST with closed eyes (114.81%), SEBT (43.76%). The increase of strength and balance were maintained in a second baseline session. There was no change for quality of life between first baseline and intervention period. CONCLUSION: These findings indicate that the CLT program is a useful exercise program that can help improve the physical activity of cancer patients who have a reluctance to move by positively affecting cancer patients' balance and leg strength.

Effects of Changes in Glycosylation Sites on Secretion of Recombinant Human Erythropoietin in Cultured CHO Cells

  • Lee, H. G;Lee, P. Y.;Lee, Y. K.;Kim, S. J.;H. K. Chung;M. K. Seo;Park, J. K.;K. S. Min;W. K. Chang
    • Korean Journal of Animal Reproduction
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    • v.27 no.4
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    • pp.299-307
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    • 2003
  • The effects of additions/deletions in glycosylated residues of recombinant human EPO (rhEPO) produced in CHO-K1 on their secretion were examined. hEPO cDNA was amplified from human liver mRNA and cloned into the pCR2.1 TOPO. Using overlapping-extension site-directed mutagenesis method, glycosylation sites at 24th, 38th, 83rd, and 126th were respectively or accumulatively removed by substituting its asparagine (or serine) with glutamine. To add novel glycosylation sites, 69 and 105th leucine was mutated to asparagine. Mutant and wild type rhEPO constructs were cloned into the pcDNA3 expression vector with CMV promoter and transfected into CHO cell line, CHO-K1, to produce mutant rhEPO mutant rhEPO proteins. Enzyme-linked immunosorbant assay (ELISA) and Western analysis with monoclonal anti-EPO antibody were performed using supernatants of the cultures showing transient and stable expressions respectively. Addition of novel glycosylation reduced rhEPO secretion dramatically while deletion mutants had little effect except some double deletion mutants ($\Delta$24/83 and $\Delta$38/83) and triple mutant ($\Delta$24/38/83). This fact suggests that not single but combination of changes in glycosyl groups affect secretion of rhEPO in cell culture, possibly via changes in their conformations.

Biocatalytic Production of Aldehyde by a Methanol Utilizing Yeast, Hansenula nonfermentans KYP-l Grown in Methanol-limited Continuous Culture

  • Yoon, Byung-Dae;Kim, Hee-Sik;Kwon, Tae-Jong;Yang, Ji-Won;Kwon, Gi-Seok;Lee, Hyun-Sun;Ahn, Jong-Seog;Mheen, Tae-Ick
    • Journal of Microbiology and Biotechnology
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    • v.2 no.4
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    • pp.278-283
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    • 1992
  • Aldehyde production by cells of a methanol utilizing yeast, Hansenula nonfermentans KYP-1 was improved when they were grown in a methanol-limited continuous culture, in comparison with cells grown in a batch culture. A higher cell yield was also obtained in continuous culture than in batch culture. This could be due to the fact that a lower methanol concentration was maintained in the jar fermentor to minimize growth inhibition by methanol. A maximum cell productivity of 0.219 g.$liter^{-1}.hr^{-l}$ and a cell yield of 47% were obtained at dilution rates of 0.1 $hr{-1}$ and 0.06 hr{-1}, respectively. The greatest amount of aldehyde was measured at a dilution rate of 0.08 $hr{-1}$. Under optimum reaction conditions, 915.7 mM of acetaldehyde was produced from 1.5 M ethanol after 21 hours reaction, with a conversion rate of 61%. Propionaldehyde and acrolein were produced with conversion rates of 32.7% and 44%, respectively.

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Estimation of Genetic Parameters of Some Productive and Reproductive Traits in Italian Buffalo. Genetic Evaluation with BLUP-Animal Model

  • Catillo, G.;Moioli, B.;Napolitano, F.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.6
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    • pp.747-753
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    • 2001
  • In this study, the Italian milk recorded buffalo population from 1974 to 1996 was analysed with the purpose to estimate genetic and environmental variability and provide genetic parameters for the most important economic traits. High variability between herds was evident due to the poor knowledge of feeding requirements and husbandry technology in this species compared to cattle. Age at first calving was reduced by 57 days during the considered years following efforts made in better feeding and management from 1990; on the contrary, calving interval has increased by 17 days as a consequence of forcing buffaloes to calve in spring, in order to have the peak milk yield when milk is much better paid. Average milk yield increased by 1853 kg during these years, while lactation duration was reduced by 30 days. Season of calving has no effect on all traits. Calving order has a positive effect on milk yield especially because older cows produce more milk in shorter lactations. Heritability for the age at first calving and calving interval was 0.26 and 0.05 respectively. Heritability of productive traits, milk yield and duration of the lactation was 0.19 and 0.13 respectively, with repeatabilities of 0.40 and 0.26. Genetic trend for milk yield was 2.1 kg milk/year for the bulls and 1 kg for all population. The high genetic variability of milk production as well as duration of the lactation, indicates that there are good opportunities for genetic improvement when including these traits in a selection scheme. The low genetic trend registered over 15 years of recording activity can be explained by the fact that neither progeny testing was performed or selection schemes were implemented, due to the difficulties to use artificial insemination in buffalo.

Analysis of settlements of space frame-shear wall-soil system under seismic forces

  • Jain, D.K.;Hora, M.S.
    • Earthquakes and Structures
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    • v.8 no.5
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    • pp.1255-1276
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    • 2015
  • The importance of considering soil-structure interaction effect in the analysis and design of RC frame buildings is increasingly recognized but still not penetrated to the grass root level owing to various complexities involved. It is well established fact that the soil-structure interaction effect considerably influence the design of multi-storey buildings subjected to lateral seismic loads. The shear walls are often provided in such buildings to increase the lateral stability to resist seismic lateral loads. In the present work, the linear soil-structure analysis of a G+5 storey RC shear wall building frame resting on isolated column footings and supported by deformable soil is presented. The finite element modelling and analysis is carried out using ANSYS software under normal loads as well as under seismic loads. Various load combinations are considered as per IS-1893 (Part-1):2002. The interaction analysis is carried out with and without shear wall to investigate the effect of inclusion of shear wall on the total and differential settlements in the footings due to deformations in the soil mass. The frame and soil mass both are considered to behave in linear elastic manner. It is observed that the soil-structure interaction effect causes significant total and differential settlements in the footings. Maximum total settlement in footings occurs under vertical loads and inner footings settle more than outer footings creating a saucer shaped settlement profile of the footings. Each combination of seismic loads causes maximum differential settlement in one or more footings. Presence of shear wall decreases pulling/pushing effect of seismic forces on footings resulting in more stability to the structures.

Quality of Life in Ovarian Cancer Patients Choosing to Receive Salvage Chemotherapy or Palliative Treatment

  • Srisuttayasathien, Manasawee;Khemapech, Nipon
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7669-7674
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    • 2013
  • Background: The hypothesis that patients who primarily progress on two consecutive chemotherapy regimens without evidence of clinical benefit may opt for supportive care was investigated. The purpose was to determine the quality of life in recurrent ovarian cancer patients choosing to receive salvage chemotherapy in addition to supportive care or palliative care alone. A secondary objective was to evaluate factors that affect quality of life in ovarian cancer patients. Materials and Methods: A descriptive study was conducted in patients who had histological confirmed epithelial ovarian cancer and failed to respond to at least one regimen of chemotherapy, coming for treatment at the King Chulalongkorn Memorial Hospital in Bangkok, Thailand over a six-month period from August 2012-March 2013. Each patient was asked to complete the FACT-G and a general personal questionnaire. The median quality of life score was analyzed. The Mann Whitney U Test was used to compare the difference between salvage chemotherapy and palliative care groups, and the Kruskal Wallis was used to evaluate other variables. Results: Thirty-eight ovarian cancer patients were identified who failed to respond to chemotherapy. Of the 38, 30 chose salvage chemotherapy and eight palliative care for further treatment. By histology the carcimnomas were predominantly endometrioid subtype and poorly differentiated. The majority of patients in this study had FIGO stage III, and ECOG status 0-1. The median quality of life score was 76.3 (35.8-94.0), with no significant differences between the groups. Factors associated with the quality of life were the ECOG score and number of chemotherapeutic courses. Conclusions: In the setting of refractory or recurrent epithelial ovarian cancer, patients who receive salvage chemotherapy have comparable quality of life scores with patients treated with palliative care alone, providing a contrast with previous studies.

An Analysis of Container Logistics System by Computer Simulation (시뮬레이션에 의한 컨테이너 물류시스템의 분석에 관하여(BCTOC를 중심으로))

  • 유승열;여기태;이철영
    • Journal of the Korean Institute of Navigation
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    • v.21 no.1
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    • pp.1-11
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    • 1997
  • Because of the sharp increase of its export and import container cargo volumes contrast to the lack of related Container Terminal facility, equipment and inefficient procedure, there is now heavy container cargo congestions in Pusan Container Terminal. As a result of such a situation, many container ships avoid their calls into Pusan port. This is a major cause that in tum kads to weakening intemational competitiveness of the Korean industry. This study, therefore, aims are to make a quantitative analysis of Container Terminal System through the computer simulation, especially focusing on its 4 sub-system of a handling system, 'it is checked whether the current operation is being performed effectively through the computer simulation. The overall findings are as folIows; Firstly, average tonnage of the ships visiting the BCTOC was 32,360 G/T in from January '96, to may '96. The average arrival interval and service time of container ships at BCTOC are 5.63 hours and 18.67 hours respectively. Ship's arrival and service pattern at BCTOC was exponential distribution with 95% confidence and Erlang-4 distribution with 99% confidence. Secondly, average waiting time and number of ships was 9.9 hours, 235 ships(38%) among 620 ships. Number of stevedoring container per ship was average 747.7 TED, standard deviation 379.1 TEU and normal distribution with 99% confidence. Thirdly, from the fact that the average storage days of containers at BCTOC are 2.75 days (3.0 days when import, 2.5 days when export). it is founds that most containers were transfered to the off-dock storage areas with the free periods(5 days when import, 4 days when export), the reason for which is considered to be the insufficient storage area at BCTOC. Fourthly, in the case of gate in-out at BCTOC, occupied containers and emptied containers are 89% and 11% respectively in the gate-in, 75% and 25% seperately in the gate-out. Finally, from the quantitative analysis results for container terminal at BCTOC, ship's average wating time of ships was found to be 20.77 hours and berth occupancy rate(${\rho}$) was 0.83. 5~6 berths were required in order that the berth occupancy rate(${\rho}$) may be maintained up to 60% degree.

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Effects of employees' perceptions of CSR legitimacy on their citizenship behaviors: The role of moderation by CEO's visionary leadership (기업의 사회적 책임 활동에 대한 정당성 인식이 종업원의 조직시민행동에 미치는 영향에 관한 연구: CEO의 비전적 리더십의 조절효과를 중심으로)

  • Lee, Soojung;Yoon, Jeongkoo
    • Knowledge Management Research
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    • v.13 no.4
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    • pp.31-54
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    • 2012
  • This study examines whether employees' legitimacy perceptions of corporate social responsibility (CSR) affect their organizational citizenship behavior (OCB). It also investigates whether CEO's visionary leadership can moderate this causal relationship. CSR legitimacy is defined in the current study as employees' personal beliefs about the appropriateness of corporate CSR activities. In fact, employees evaluate the appropriateness of CSR activity based on its consistency with corporate philosophy (e.g. corporate mission, vision, and values) which functions as employees' referencial belief structure. If CSR activity is perceived as one of firm's effort to fulfill its mission, vision, and values, which means that espoused theory and theory-in-use of CSR activity are congruent, employees will consider firm's CSR activity as legitimate. If, however, employees think that CSR activity is not congruent with firm's mission, vision, and values, which means that espoused theory and theory-in-use of CSR activity are inconsistent, they will perceive that CSR activity of their firm is not legitimate. In the current study, we propose that employees who perceive that the CSR activity of their firm is legitimate are more likely to engage in OCB. In addition, we hypothesize that CEO's visionary leadership can strengthen the positive effect of employees' perception of CSR legitimacy on their OCB. We tested these hypotheses with the sample of 383 employees from 32 companies listed on DJSI (Dow Jones Sustainability Index) Korea 2009. We employed the HLM (hierarchical linear modeling) program to decompose the multi-level random effects. We found that CSR legitimacy perceptions of employees increase employees' OCB and that CEO's visionary leadership moderates this relationship. We discussed implications of these findings in more detail.

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