• Title/Summary/Keyword: FAB

Search Result 549, Processing Time 0.026 seconds

Virtual Environment Hardware-In-the-Loop Simulation for Verification of OHT Controller (OHT 제어기 검증을 위한 가상환경 HIL 시뮬레이션)

  • Lee, Kwan Woo;Lee, Woong Geun;Park, Sang Chul
    • Journal of the Korea Society for Simulation
    • /
    • v.28 no.4
    • /
    • pp.11-20
    • /
    • 2019
  • This paper presents a HILS(Hardware-In-the-Loop Simulation) approach for the verification of the OHT (Overhead Hoist Transport) controller in a semiconductor FAB. Since hundreds of OHTs can run simultaneously on the OHT network of a FAB, the full verification of the OHT controller is very essential to guarantee the stableness of the material handling system. The controller needs to fully consider not only normal situations but also abnormal situations that are difficult to predict. For the verification of the controller, we propose a HILS approach using a virtual environment including OHTs on a rail network, which can generate abnormal situations. The proposed HILS approach has been implemented and tested with various examples.

${\beta}$-ketoacyl-acyl carrier protein synthases for fatty acid biosynthesis in bacteria

  • Lee, Hee-Jung;Youn, Youn-Ji;Ok, Jung-In;Lee, Jung-Won;Park, Hyo-Young;Cho, Kyung-Hae;Choi, Keum-Hwa
    • Proceedings of the PSK Conference
    • /
    • 2002.10a
    • /
    • pp.315.3-316
    • /
    • 2002
  • A universal set of genes encodes the components of dissociated. type II. fa11y acid synthase system that is responsible for producing the multitude of fa11y acid structures found in bacterial membranes. We examined the biochemical basis for the production of fatty acids by bacteria. Several genes from HaemophHus influenzae Rd and three genes from Enterococcus faecalis V583 were predicted to encode homologs of the ${\beta}$-ketoacyl-acyl carrier protein synthases I or II or III of Escherichia coli(FabB or BabF, or FabH)were identified in the genomic database. The protein products were expressed. purified, and biochemically characterized. efFabH and hF abH carried out the initial condensation reaction of fatty acid biosynthesis with acetyl-Coenzyme A as a primer. and hFabB and efFabF1 carried out the elongation condensation reaction of fatty acid biosynthesis with myrixtoyl-ACP.

  • PDF

Comparison of the Pediatric Balance Scale and Fullerton Advanced Balance Scale for Predicting Falls in Children With Cerebral Palsy

  • Kim, Gyoung-mo
    • Physical Therapy Korea
    • /
    • v.23 no.4
    • /
    • pp.63-70
    • /
    • 2016
  • Background: The Pediatric Balance Scale (PBS) and the Fullerton Advanced Balance (FAB) scale were used to assess balance function in patients with balance problem. These multidimensional clinical balance scales provide information about potential risk factors for falls. Objects: The purpose of this study was to investigate and compare the predictive properties of the PBS and FAB scales relative to fall risk in children with cerebral palsy (CP) using a receiver operating characteristic analysis. Methods: In total, 49 children with CP (boy=21, girl=28) who were diagnosed with level 1 or 2 according to the Gross Motor Function Classification System participated in this study. The PBS and FAB were performed, and verified cut-off score, sensitivity, specificity, and the area of under the curve (AUC). Results: In this study, the PBS scale was as a predictive measure of fall risk, but the FAB was not significant in children with CP. A cut-off score of 45.5 points provided optimal sensitivity of .90 and specificity of .69 on the PBS, and a cut-off score of 21.5 points provided optimal sensitivity of .90 and specificity of .62 on the FAB. Both scales showed moderately accurate of AUC with .79 and .76, respectively. Conclusion: The PBS is a useful screening tool for predicting fall risk in children with cerebral palsy, and those who score 45.5 or lower indicate a high risk for falls and are in need of balance intervention.

Neutralizing Chimeric Mouse-human Antibodies against Burkholderia pseudomallei Protease: Expression, Purification and Characterization

  • Chan, Shzu-Wei;Ong, Guan-Im;Nathan, Sheila
    • BMB Reports
    • /
    • v.37 no.5
    • /
    • pp.556-564
    • /
    • 2004
  • A recombinant Fab monoclonal antibody (Fab) C37, previously obtained by phage display and biopanning of a random antibody fragment library against Burkholderia pseudomallei protease, was expressed in different strains of Escherichia coli. E. coli strain HB2151 was deemed a more suitable host for Fab expression than other E. coli strains when grown in media supplemented with 0.2% glycerol. The expressed Fab fragment was purified by affinity chromatography on a Protein G-Sepharose column, and the specificity of the recombinant Fab C37 towards B. pseudomallei protease was proven by Western blotting, enzyme-linked immunosorbent assay (ELISA) and by proteolytic activity neutralization. In addition, polyclonal antibodies against B. pseudomallei protease were produced in rabbits immunized with the protease. These were isolated from high titer serum by affinity chromatography on recombinant-Protein A-Sepharose. Purified polyclonal antibody specificity towards B. pseudomallei protease was proven by Western blotting and ELISA.

Content Validity of a Korean-Translated Version of a Fullerton Advanced Balance Scale: A Pilot Study

  • Kim, Gyoung-mo
    • Physical Therapy Korea
    • /
    • v.22 no.4
    • /
    • pp.51-61
    • /
    • 2015
  • The purpose of this study were to translate the Fullerton Advanced Balance (FAB) scale into Korean and to verify the content validity by utilizing a back-translation method with a view to assessing balance function and the risk of falling in a clinical research setting. This research was conducted in six steps. First, three Korean physical therapists translated the FAB scale into Korean. Second, two bilingual professors of physical therapy and a physical therapist evaluated translation conformity of Korean-translated FAB scale. In the third and fourth steps, twelve physical therapists evaluated the degree of translation comprehension, and a translator back-translated the Korean FAB scale into the original language. Fifth, a bilingual professor of physical therapy and two native speakers evaluated the technical and conceptual equivalence between the original and translation versions. In this process, inappropriate translated items were revised using recommended substitute words or sentences, and all items were evaluated on the basis of three points or more on a rating scale in terms of translation comprehension, and the technical and conceptual equivalence of the back-translation. In the sixth and last step, the translation verification committee completed the final Korean version. The above process indicated that the content validity of the Korean-translated FAB scale was established by means of systematic translation methods, and it can therefore be used to assess balance function and the risk of falls in a clinical research setting.

Facial Emotion Recognition in Older Adults With Cognitive Complaints

  • YongSoo Shim
    • Dementia and Neurocognitive Disorders
    • /
    • v.22 no.4
    • /
    • pp.158-168
    • /
    • 2023
  • Background and Purpose: Facial emotion recognition deficits impact the daily life, particularly of Alzheimer's disease patients. We aimed to assess these deficits in the following three groups: subjective cognitive decline (SCD), mild cognitive impairment (MCI), and mild Alzheimer's dementia (AD). Additionally, we explored the associations between facial emotion recognition and cognitive performance. Methods: We used the Korean version of the Florida Facial Affect Battery (K-FAB) in 72 SCD, 76 MCI, and 76 mild AD subjects. The comparison was conducted using the analysis of covariance (ANCOVA), with adjustments being made for age and sex. The Mini-Mental State Examination (MMSE) was utilized to gauge the overall cognitive status, while the Seoul Neuropsychological Screening Battery (SNSB) was employed to evaluate the performance in the following five cognitive domains: attention, language, visuospatial abilities, memory, and frontal executive functions. Results: The ANCOVA results showed significant differences in K-FAB subtests 3, 4, and 5 (p=0.001, p=0.003, and p=0.004, respectively), especially for anger and fearful emotions. Recognition of 'anger' in the FAB subtest 5 declined from SCD to MCI to mild AD. Correlations were observed with age and education, and after controlling for these factors, MMSE and frontal executive function were associated with FAB tests, particularly in the FAB subtest 5 (r=0.507, p<0.001 and r=-0.288, p=0.026, respectively). Conclusions: Emotion recognition deficits worsened from SCD to MCI to mild AD, especially for negative emotions. Complex tasks, such as matching, selection, and naming, showed greater deficits, with a connection to cognitive impairment, especially frontal executive dysfunction.

Analytical Separation of Isomeric Saponins by LC/MS

  • Young, Han-Suk;Park, Jong-Cheol;Choi, Jae-Sue
    • Korean Journal of Pharmacognosy
    • /
    • v.19 no.4
    • /
    • pp.248-250
    • /
    • 1988
  • The application of LC/MS system with FRIT-FAB LC/MS interface in both positive and negative ion modes to the analytical separation of isomeric saponins was studied. The two isomeric saponins such as rosamultin and arjunetin were well separated and analyzed FRIT, FAB LC/MS system. This is another examples to structure elucidation of natural products.

  • PDF

Process Time reduction of Semiconductor using BCR (반도체 단위공정시간 단축에 관한 연구)

  • 빅종화;한영신;이칠기
    • Proceedings of the Korea Society for Simulation Conference
    • /
    • 2003.06a
    • /
    • pp.135-140
    • /
    • 2003
  • 반도체 제조 공정 중 FAB공정은 수많은 단위공정들로 이루어져 있고, 한 Lot에 대한 모든 공정을 진행하는 데에는 약 1개월 이상이 소요된다. 반도체 산업의 특성상 고객이 원하는 제품을 최단 시간 내에 생산을 해서 적기에 제품을 공급해야만 최대의 수익을 올릴 수가 있다. 그러므로 FAB공정의 공기단축은 반도체 생산에서 중요한 부분이 된다고 할 수 있다. 본 연구는 FAB공정 중 단위공정과 단위공정 사이에서 이루어지는 작업을 라인자동화를 통한 새로운 모델을 적용해서 단위공정에서 소요되는 시간을 단축함으로써, 반도체 제조의 생산성향상 및 공기단축을 목적으로 한다.

  • PDF