• 한국환경복원기술학회지
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• 제18권4호
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• pp.15-27
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• 2015

The objectives of this study are to analyze the quantitative ecological principal components of Korean Peninsula using the multivariate spatial environmental datasets and to compare the ecological difference between South and North Korea. Ecological maps with GIS(Geographical Information System) are constructed by PCA(Principal Component Analysis) based on seventeen raster(cell based) variables at 1km resolution. Ecological differences between South and North Korea are extracted by Factor Analysis using ecosystem maps masked from Korean ones. Spatial data include SRTM(Shuttle Radar Topography Mission), Temperature, Precipitation, SWC(Soil Water Content), fPAR(Fraction of Photosynthetically Active Radiation) representing for a productivity, and SR(Solar Radiation), which all cover Korean peninsula. When it performed PCA, the first three scores were assigned to red, green, and blue color. This color triplet indicates the relative mixture of the seventeen environmental conditions inside each ecological region. The first red one represents for 'physiographic conditions' worked by high elevation and solar radiation and low temperature. The second green one stands for 'seasonality' caused by seasonal variations of temperature, precipitation, and productivity. The third blue one means 'wetness condition' worked by high value such as precipitation and soil water contents. FA extraction shows that South Korea has relatively warm and humid ecosystem affected by high temperature, precipitation, and soil water contents whereas North Korea has relatively cold and dry ecosystem due to the high elevation, low temperature and precipitation. Results would be useful at environmental planning on inaccessible land of North Korea.

• Asian Pacific Journal of Cancer Prevention
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• 제15권23호
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• pp.10209-10215
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• 2015

To assess the contribution of tumor necrosis factor $(TNF){\beta}$ +252 polymorphisms to risk and prognosis of hepatocellular carcinoma (HCC), we enrolled 150 pairs of sex- and age-matched patients with HCC, patients with cirrhosis alone, and unrelated healthy controls. $TNF{\beta}$ +252 genotypes were determined by polymerase chain reaction with restriction fragment length polymorphism. Multivariate analysis indicated that $TNF{\beta}$ G/G genotype [odds ratio (OR), 3.64; 95%CI, 1.49-8.91], hepatitis B surface antigen (OR, 16.38; 95%CI, 8.30-32.33), and antibodies to hepatitis C virus (HCV) (OR, 39.11; 95%CI, 14.83-103.14) were independent risk factors for HCC. There was an additive interaction between $TNF{\beta}$ G/G genotype and chronic hepatitis B virus (HBV)/HCV infection (synergy index=1.15). Multivariate analysis indicated that factors associated with $TNF{\beta}$ G/G genotype included cirrhosis with Child-Pugh C (OR, 4.06; 95%CI, 1.34-12.29), thrombocytopenia (OR, 6.55; 95%CI, 1.46-29.43), and higher serum ${\alpha}$-fetoprotein concentration (OR, 2.53; 95%CI, 1.14-5.62). Patients with $TNF{\beta}$ G/G genotype had poor cumulative survival (p=0.005). Cox proportional hazard model indicated that $TNF{\beta}$ G/G genotype was a biomarker for poor HCC survival (hazard ratio, 1.70; 95%CI, 1.07-2.69). In conclusion, there are independent and additive effects between $TNF{\beta}$ G/G genotype and chronic HBV/HCV infection on risk for HCC. It is a biomarker for poor HCC survival. Carriage of this genotype correlates with disease severity and advanced hepatic fibrosis, which may contribute to a higher risk and poor survival of HCC. Chronic HBV/HCV infected subjects with this genotype should receive more intensive surveillance for early detection of HCC.

• 한국항해항만학회지
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• 제34권3호
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• pp.229-234
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• 2010

본 연구는 인천항 배후단지를 운영함에 있어 취급되는 품목 중 어떠한 품목이 항만 배후단지 운영에 기여하는지를 선정하고 그에 따른 시사점을 제공하는 것을 연구의 목적으로 하였으며, 대상은 아암물류1단지와 4부두 배후지로 선정하였다. 연구의 방법으로 요인분석 및 AHP 분석을 사용하였다. 선행연구를 통하여 물동량 창출가능성을 비롯한 총 11가지의 하위평가요인을 선정하였고, 요인분석을 통해 효율적인 관리를 포함한 총 4가지의 상위평가요인들이 그룹핑 되었다 AHP분석을 통해 하위평가요인들의 우선순위를 산정한 결과 물동량 창출 가능성 측면이 배후단지 운영시 가장 중요한 요인으로 선정되었다. 그리고 수출입액과 수출입 중량을 기준으로 농산물, 철강/비철금속, 전자부품을 평가 품목대안으로 선정하고 분석을 실시한 결과, 전자부품이 인천항 배후단지에서 취급중인 화물 중 운영적으로 가장 많은 기여를 하는 것으로 나타났다. 따라서 전자부품과 같은 물동량 증가 가능성이 많은 화물에 대한 전략적인 관리가 필요하며 본 연구가 향후 개장될 인천항 아암물류2단지와 인천신항 배후단지의 유치품목 선정에 있어 중요한 지표로 사용될 수 있을 것이라 판단된다.

• 대한치과교정학회지
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• 제41권4호
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• pp.288-296
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• 2011

Objective: The purposes of this study were to evaluate the relationship between the dental and basal arch forms; to analyze their differences in the tapered, ovoid, and square arch forms in normal occlusion by using three-dimensional (3D) virtual models; and to test the hypothesis that the overjet and maxillomandibular basal arch width difference have a significantly positive correlation. Methods: Seventy-seven normal occlusion plaster casts were examined by 3D scanning. Facial axis (FA) and WALA points were digitized using the Rapidform 2006 software. The dimensions of the dental and basal arches and the overjet were measured. The samples were classified into 3 groups according to arch forms: tapered (n = 20), ovoid (n = 20), and square (n = 37). Analysis of variance (ANOVA) was used to compare the dental and basal arch dimensions. The Pearson correlation coefficients between the intercanine as well as the intermolar widths at the FA and WALA points were calculated. Results: With regard to the basal arch dimensions, the tapered arch form showed a larger mandibular intermolar depth than the ovoid. Strong correlations were noted between the basal and dental intermolar widths in both the upper and lower arches (r = 0.83 and 0.85, respectively). Moderate correlation was found between the upper and lower intercanine widths (r = 0.65 and 0.48, respectively). Conclusions: The 3 dental arch form groups differed only in some dimensions of the skeletal arch. Moderate correlations were found between the basal and dental intercanine widths. These findings suggest that the basal arch may not be a principle factor in determining the dental arch form.

• 한국전자파학회논문지
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• 제16권11호
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• pp.1059-1066
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• 2005

본 논문은 피드포워드 전력 증폭기의 효율 개선을 위한 도허티 증폭기의 적용에 관한 연구이다. 성능 분석을 위하여 중심 주파수 2.14 GHz의 WCDMA 4FA신호를 인가하여 평균 출력 전력 15 W에서 측정하였다. 적용한 도허티 증폭기는 동급 class AB 증폭기와 비교하여 고효율 저선형성의 특성을 나타내며 효율 개선을 위하여 피드포워드 전력 증폭기(FPA)의 주 증폭기로 사용되었다. 특성 변화를 분석하기 위해 선형성과 효율 특성이 다른 2가지 종류의 도허티 증폭기를 적용하였으며 각각의 FPA들은 평균 출력 15 W에서 효율은 $2\%$ 이상의 개선을 보였지만 선형성은 1.5 dBc 이상 저하되는 특성을 나타냈다. 저하된 선형성을 개선하기 위하여 부가적으로 오차 루프의 결합 계수(CF)와 오차 증폭기의 용량을 변화시켰다. CF와 오차 증폭기의 용량 변화로 효율 개선과 높은 선형성을 얻을 수 있었고 도허티 증폭기가 35 dBc 이상의 선형성을 유지하면 부가적인 변화 없이 평균 출력 전력 15 W에서 $2\%$ 이상의 효율 개선과 충분한 선형성을 얻을 수 있다.

• 한국ITS학회 논문지
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• 제14권1호
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• pp.13-21
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• 2015

본 연구에서는 두 가지 형태의 공용차로 운영 효율성에 초점을 맞추어 분석을 수행하였다. 직진 우회전 공용차로의 경우 인접한 직진차로에 비해 이용률이 현저히 떨어지는 것으로 나타났으며 그로 인해 신호운영의 효율성이 떨어지는 것으로 분석되었다. 이를 개선하기 위해서는 우선 차로별 교통량 수집을 통한 보다 정교한 신호최적화가 필요하다 할 수 있으며, 나아가 운전자 교육, 홍보를 통해 공용차로의 이용률을 제고하여야 할 것이다. 좌회전 유턴 공용차로에서는 유턴 교통량에 대한 대향 우회전 교통량 비율에 따라 포화교통류율이 감소한다는 것을 확인할 수 있었다. 하지만 유턴, 우회전 차량간 간섭에 따른 현실적인 포화교통류율 보정치를 개발하기 위해서는 차량간 간섭이 일어날 가능성에 대한 확률모형의 정립이 필요한 것으로 판단된다.

• 융합보안논문지
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• 제15권6_1호
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• pp.25-31
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• 2015

전쟁에서 승리하느냐 실패하느냐는 국제정세나 국민의 애국심과 단결력, 상대적 전투력 등 여러 요인에 의해 결정된다. 여기에서는 제2차 세계대전 초기 독일 프랑스 전역에서의 독일군 기동계획과 전쟁 말기인 1944년 겨울 발지전투를 군사보안 관점에서 성공과 실패 요인을 분석하고자 한다. 앞에서 제시한 각각의 전역은 독일이 아르덴느 산맥을 돌파하여 연합군의 주요부대를 타격했던 것은 동일하나 초기작전은 전격전의 전형적인 모습을 보여준 반면에 발지전투는 유사한 기동계획을 기획하고 시행했지만 결과는 독일의 패망을 앞당기는 촉매제 역할을 하게 되었다. 전장에서 승리하기 위해서는 적의 정보운용 능력을 역이용하거나 거부하고 아군은 적으로부터 방해받지 않고 정보를 수집, 처리, 전파할 수 있는 유리한 위치를 갖는 것이다. 이는 적보다 어떻게 정보를 효과적으로 운용하는 것이 전장 승리의 요체인가를 보여준다. 제2차 세계대전시 독일 프랑스 전역과 발지 전투에서의 독일군 기동계획은 아주 유사하게 기획되고 시행되었다. 그러나 그 결과는 극단적으로 달랐다. 작전계획을 기획하고 결심하는 과정에서 군사보안과 정보수집 등이 얼마나 중요한 것인지를 잘 보여주는 역사적 사실의 하나이다.

• Advances in concrete construction
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• 제11권5호
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• pp.419-428
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• 2021

The pH of cement-based materials (CBMs) is an important factor for their durability, sustainability, and long service life. Currently, the use of supplementary cementitious materials (SCMs) is becoming mandatory due to economic, environmental, and sustainable issues. There is a decreasing trend in pH of CBMs due to incorporation of SCMs. The determination of numerical values of pH is very important for various low and high volume SCMs blended cement mortars for the better understanding of different defects and durability issues during their service life. In addition, the effect of cement hydration and pozzolanic reaction of SCMs on the pH should be determined at initial and later ages. In this study, the effect of low and high-volume fly ash (FA) and ground granulated ballast furnace slag (GGBFS) cement mortars in different curing conditions on their pH values has been determined. Thermal gravimetric analysis (TGA) was carried out to support the findings from pH measurements. In addition, thermal conductivity (k-value) and strength activity indices of these cement mortars were discussed. The results showed that pH values of all blended cement mortars were less than ordinary Portland cement (OPC) mortar in all curing conditions used. There was a decreasing tendency in pH of all mortars with passage of time. In addition, the pH of cement mortars was not only dependent on the quantity of Ca(OH)₂. The effect of adding SCMs on the pH value of cement mortar should be monitored and measured for both short and long terms.

• Bulletin of the Korean Chemical Society
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• 제30권5호
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• pp.1121-1126
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• 2009

This paper describes a pattern recognition method of Magnoliae flos based on a gas chromatographic/mass spectrometric (GC/MS) analysis of the essential oil components. The botanical drug is mainly comprised of the four magnolia species (M. denudata, M. biondii, M. kobus, and M. liliflora) in Korea, although some other species are also being dealt with the drug. The GC/MS separation of the volatile components, which was extracted by the simultaneous distillation and extraction (SDE), was performed on a carbowax column (supelcowax 10; 30 m{\time}0.25 mm{\time}0.25{\mu}m$) using temperature programming. Variance in the retention times for all peaks of interests was within RSD 2% for repeated analyses (n = 9). Of the 74 essential oil components identified from the magnolia species, approximately 10 major components, which is $\alpha$-pinene, $\beta$-pinene, sabinene, myrcene, d-limonene, eucarlyptol (1,8-cineol), $\gamma$-terpinene, p-cymene, linalool, $\alpha$-terpineol, were commonly present in the four species. For statistical analysis, the original dataset was reduced to the 13 variables by Fisher criterion and factor analysis (FA). The essential oil patterns were processed by means of the multivariate statistical analysis including hierarchical cluster analysis (HCA), principal component analysis (PCA) and discriminant analysis (DA). All samples were divided into four groups with three principal components by PCA and according to the plant origins by HCA. Thirty-three samples (23 training sets and 10 test samples to be assessed) were correctly classified into the four groups predicted by PCA. This method would provide a practical strategy for assessing the authenticity or quality of the well-known herbal drug, Magnoliae flos.

• Asian Pacific Journal of Cancer Prevention
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• 제15권12호
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• pp.4951-4956
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• 2014

Purpose: To investigate IQGAP1 and IQGAP2 expression in hepatocellular carcinoma (HCC) and itsassociation with HCC clinicopathological characteristics and survival outcomes. Methods: IQGAP1 and IQGAP2 mRNA and protein were measured in HCC tissues, para-tumor tissues and normal tissues by RT-PCR and Western blotting. We further examined 150 HCC samples with adjacent para-tumor tissues and 11 normal specimens by immunohistochemistry to evaluate the correlation of IQGAP1 and IQGAP2 with clinicopathological features and prognosis. Results: IQGAP1 mRNA and protein were up-regulated while IQGAP2 mRNA and protein were down-regulated in human HCC tissues compared with para-tumor and normal liver tissues (p<0.05). IQGAP1 expression was higher in primary HCC (122/150, 81.3%) than matched adjacent tissues (30/150, 20%, p<0.001), whereas IQGAP2 was lower (31/150, 20.7% as compared to 112/150, 74.7%, P<0.001). Positive IQGAP1 expression correlated with larger tumor size (p=0.002), advanced TNM stage (p=0.002) and tumor differentiation (III and IV, p=0.034). Negative IQGAP2 expression was significantly associated with larger tumor size (p=0.009), multicentric tumor occurrence (p=0.01), advanced TNM stage (0.009) and tumor differentiation (III and IV, p=0.020). Survival analysis revealed that patients with either IQGAP1+ or IQGAP2-tumors had significantly reduced disease-free survival (p<0.001 and 0.006 respectively) and overall survival (p<0.001 for both). Multivariate analysis showed that IQGAP1/2 switch was an independent prognosis factor for disease-free survival (HR=2.824) and overall survival (HR=2.189). Conclusion: Positive IQGAP1 and negative IQGAP2 expression were closely correlated with tumor progression and could be used as adjunctive biomarkers to improve prognostication for HCC patients.