• Title/Summary/Keyword: F.E. analysis

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Achyranthes japonica Nakai Water Extract Suppresses Binding of IgE Antibody to Cell Surface FcεRI.

  • Shim, Sun Yup;Lee, Mina;Lee, Kyung Dong
    • Preventive Nutrition and Food Science
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    • v.21 no.4
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    • pp.323-329
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    • 2016
  • Achyranthes japonica Nakai (AJN) water extract has a variety of physiological properties, including anti-diabetic, anti-cancer, anti-inflammatory, anti-microbial, and anti-oxidative activities. In the present study, the inhibitory effects of AJN extract were investigated in high affinity immunoglobulin E receptor ($Fc{\varepsilon}RI$)-mediated KU812F cells activation. AJN extract showed suppressive effects on histamine release and intracellular calcium [$Ca^{2+}$]i elevation from anti$Fc{\varepsilon}RI$ antibody (CRA-1)-stimulated cells in a dose-dependent manner. Flow cytometric analysis showed that AJN extract treatment caused a dose-dependent decrease in the cell surface $Fc{\varepsilon}RI$ expression and the binding between the cell surface $Fc{\varepsilon}RI$ and the IgE antibody. Moreover, reverse transcription-polymerase chain reaction analysis showed that levels of the mRNA for the $Fc{\varepsilon}RI$ ${\alpha}$ chain was decreased by treatment with AJN extract. These results indicate that AJN extract may exert anti-allergic effects via the inhibition of calcium influx and histamine release, which occurs as a result from the downregulation of the binding of IgE antibody to cell surface $Fc{\varepsilon}RI$. This mechanism may occur through $Fc{\varepsilon}RI$ expression inhibition.

A Study on the Development of the Weapon System Effectiveness Indices (I) (한국적 무기체계 효과지수 개발에 관한 연구 (I) -무기체계 효과측정 방법론-)

  • Min, Kye-Ryo;Park, Kyung-Soo
    • Journal of the military operations research society of Korea
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    • v.5 no.1
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    • pp.123-135
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    • 1979
  • Weapon System effectiveness indices are a key factor to the cost-effectiveness analysis in the process of allocating national resources in an optimal fashion. First part of this paper reviews the need of weapon -effectiveness indices, historical development of methodologies on military strength evaluation with various models of indices, and the interrelation-ship between weapon effectiveness indices and war-game. Second part of this paper analyzes the concepts and usage of the already developed methodologies, i .e., index of power, weapon lethality index (W.L.I.), index of fire power potential (I.F.P), fire power potential (F. P. P), and weapon effectiveness indices/weighted unit value (W. E. I/W. U. V.). Finally, weaknesses and limits of these methodologies are compared and evaluated. Result of this research shows that the W. L. I, I. F. P, and F. P. P seem to possess many non-scientific or ambiguous facets, but the W. E. I/W. U. V method produces more detailed, inclusive, and reasonable indices. The paper concludes with the emphasis on the importance of the provision of the theoretical bases to develop effectiveness indices which can be used to evaluate Korean weapon systems, and the early establishment of a specialized research group to manage and develop methodologies on the weapon effectiveness indices.

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The Characteristics Analysis of Single Phase LSPM Synchronous Motor by changing Design Parameter (단상 LSPM 동기 전동기의 설계 변수 변화에 따른 특성 해석)

  • Hong, Sook-Hyun;Ko, Kwon-Min;Park, Chan-Bae;Choi, Jae-Young
    • Proceedings of the KIEE Conference
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    • 2003.10b
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    • pp.86-88
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    • 2003
  • The efficiency of electric machine is important due to increase of interest about energy saving. Single Phase Line Start Permanent Magnet Synchronous Motor has high efficiency and power factor. LSPMSM offer a high efficiency as compared induction motor which are used in the home appliance. The analysis and design of LSPMSM is difficult because of unbalanced rotating magnetic field, nonlinear characteristics and rotor saliency. To consider these effects, F.E.M(Finite Element Methods) is coupled equivalent circuit methods. In this paper, a methods of analysis and design using F.E.M and equivalent circuit is represented.

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The Characteristic Analysis of a Single-Sided Linear Induction Motor due to the Lateral Displacement of the Primary and the Secondary by the F.E.M. (유한 요소법에 의한 편측식 선형유도전동기의 1차측과 2차측의 횡방향 편위에 따른 특성해석)

  • 임달호;최창규;조철직;조윤현
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.39 no.8
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    • pp.820-827
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    • 1990
  • For the purpose of investigation the thrust force, the lateral force, and the eddy current loss when the primary and the secondary of a single-sided linear induction motor is displaced in the space, this paper proposes an analysis technique for the characteristics of the eddy current induced on the secondary and the magnetic flux density distribution in the y-z plane by F.E.M. To verify the effectiveness of this analysis technique, the starting-thrust force due to a lateral displacement is compared to the experimental data.

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Identification of joint dynamics of mechanical structures using condensed F.E.M. model and experimental modal analysis (축약된 유한요소 모델과 실험적 모우드 해석을 이용한 기계구조물의 연결부 동특성 규명)

  • 최병욱;박병호;김광준
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.12 no.3
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    • pp.426-439
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    • 1988
  • Dynamic properties such as stiffness and damping of mechanical joints are essential for the accurate prediction of the dynamic behaviors of the system and subsequent improvement of the design. So far several techniques, analytical, experimental, or both have been developed. A technique using condensed F.E.M. model and Experimental Modal Analysis is presented to identify the joint structural parameters. First, modal parameters of structure are measured by certain complex frequency obtained from experiment to match with the order of the Experimental Modal Analysis model. Finally by equating the modal parameters obtained from experiment with those of the condensed system, the unknown joint structural parameters can be identified. A simulation study is conducted to investigate the accuracy of technique. The experiments are performed with ball bearings in a rotor bearing system.

Electromagnetic Analysis of 6.6kV Main Transformer for a Vessel (6.6kV급 선박용 고압 건식 변압기 최적 설계를 위한 전자계 해석)

  • Kang Moon Shick;Kim Kyung Ho;Ku Sung Whi;Cho Yun Hyun
    • Proceedings of the KIEE Conference
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    • summer
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    • pp.818-820
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    • 2004
  • This paper is described the insulation design and 3-D electromagnetic analysis of 6.6kV main transformer for a vessel by F.E.M.. To obtain the optimal design of insulation structure, the electric field stress is analyzed and estimated the proposed model A and B for the characteristics investigation according to the insulation thickness and position. And the performance characteristics of 6.6kV transformer are estimated as the equivalent circuit parameters computed by F.E.M. analysis.

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A Comparison of Resonance Parameters before and after Pharyngeal Flap Surgery:A Preliminary Report (인두피판술 전.후의 공명파라미터의 비교: 예비연구)

  • Kang, Young-Ae;Kang, Nak-Heon;Lee, Tae-Yong;Seong, Cheol-Jae
    • Phonetics and Speech Sciences
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    • v.1 no.3
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    • pp.133-144
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    • 2009
  • Pharyngeal flap surgery changes the space and shape of the oral cavity and vocal tract, and these changing conditions bring resonance change. The purpose of this study was to determine the most reliable and valuable parameters for evaluating hypernasality to distinguish two patients before and after pharyngeal flap surgery. Each patient was asked to clearly speak the vowels /a/, /i/, /u/, /e/, /o/ for voice recording. There were nine parameters: Formant (F1, F2, F3), Bandwidth (BW1, BW2, BW3), LPC energy slope ($\Delta$ |A2-A1/F2-F1|), and Band Energy (0-500 Hz, 500-1000 Hz) by each vowel. From the results of discrimination analyses on acoustic parameters, the vowels /a/, /e/ appeared to be insignificant but vowels /i/, /u/, /o/ appeared to be efficient in the separation. A 95%, 100%, and 100% recognition score could be reached when vowels /i/, /u/, and /o/ were analyzed. The results showed that F2, BW3, and LPC slope are more important parameters than the others. Finally, there is a relation between perceptual evaluation score and LPC energy slope of acoustic parameters by least square slope.

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Quantitative Analysis on the Structure of Hambaek Syncline (정량적(定量的) 해석(解析)에 의(依)한 함백향사(咸白向斜) 구조(構造) 연구(硏究))

  • Park, Rin Sik;Min, Kyung Duck
    • Economic and Environmental Geology
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    • v.13 no.3
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    • pp.141-158
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    • 1980
  • A geologic structure could be formed through various processes, because there are a number of factors which control the deformation of the Earth's crust. In geology, we could call it geological epistemology to describe exactly a geologic structure, and call it geological logics to infer logically the deforming process through which the geologic structure had been formed. Degree of legitimacy of geological logics depends upon the degree of exactness of geological epistemology. This study described quantitatively 3-dimensional Hambaek Syncline through computer analysis, and examined qualitatively into its deforming mechanism based on the results of 3-dimensional analysis of the structure. Input data for the computer analysis are dips and dip directions of bedding planes of the structure. The Hambaek Syncline disclose a minor fold group of NE-SW or NNE-SSW trend and a large scale fold of E-W trend. The conclusions of this study are as follows: (1) The fold of E-W trend is primary fold $(F_1)$ and the minor fold group of NE-SW or NNE-SSW trend secondary fold $(F_2)$. (2) Hambaek Syncline is cylindrical type fold. (3) Apparent axial trace of Hambaek syncline does not coincide with true axial trace. The apparent axial trace is $N70^{\circ}-80^{\circ}W$ in Gohan and Sabuk area, and changes to $N70^{\circ}-80^{\circ}E$ in the westward of the area, while the true axial trace is $N40^{\circ}-70^{\circ}W$ in the former, and $N60^{\circ}-80^{\circ}E$ in the latter area. (4) Westward dipping of axial plane of the minor fold group of NE-SW or NNE-SSW trend can be attributed to simple shear movements along overthrusts. (5) Angle between axial trace and the directional trace of the maximum principal compressive stress $({\sigma}_1)$ may not be perpendicular each other. The angle between them is governed by the following factors; 1) the plunge of fold axis 2) the dip of axial surface 3) cylindrisity (6) The mean axial trace of Hambaek Syncline $(F_1)$ is $N45.6^{\circ}W$, and the directional trace of ${\sigma}_1$ is $N52.4^{\circ}E$ (7) The mean axial trace of the minor fold group of NE-SW or NNE-SSW trend $(F_2)$ is $N21^{\circ}E$, and the directional trace of ${\sigma}_1$ is $N22^{\circ}W$.

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Finite element analysis or permanent magnet alternator with nonlinear load (비선형 부하를 갖는 영구자석 발전기의 유한요소 해석)

  • Hong, Ki-Rann;Hahn, Song-Yop
    • Proceedings of the KIEE Conference
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    • 1989.11a
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    • pp.53-57
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    • 1989
  • Until now, method of equivalent circuit is generally used in analyzing the characteristic of the synchronous alternator. But this method can't apply when loads are connected to alternator. In this paper, we analyzed the load characteristic of the synchronous alternator with permanant magnet using 2-dimensional finite element method having voltage source. The loads of a alternator are battary and diodes which are used to rectify. also, we used half periodic boundary condition in the F.E.M calculation

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Qualitative PCR Detection of vitamin E-enriched GM Perilla (비타민 E 강화 유전자변형 들깨에 대한 정성 PCR 분석법)

  • Kim, Jae-Hwan;Ahn, Ji-Hye;Song, Hee-Sung;Kim, Kyung-Hwan;Kim, Dong-Hern;Kim, Hae-Yeong
    • Applied Biological Chemistry
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    • v.49 no.3
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    • pp.192-195
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    • 2006
  • For the development of a qualitative PCR detection method for genetically modified perilla (Perilla frutescens), perilla species-specific gene, KAS-I (Beta-ketoacyl-ACP synthase I), was selected and validated as suitable for the use as an endogenous reference gene in perilla. Primer specificity was first tested by the means of qualitative PCR analysis. The primer pair Pfru3-F/R amplifying the perilla endogenous gene, KAS-I, gave rise to an amplicon 95 bp. No amplified product was observed when DNA samples from 15 different plants were used as templates. Qualitative PCR detection method was assayed with vitamin E-enriched GM Perilla developed in Korea. For the qualitative PCR detection method, the construct-specific detection primer pairs were constructed. The primer pair TMTO-F/R amplifying the junction region of TMT (${\gamma}$-tocopherol methyltransferase) gene and OCS (Octopine synthase) terminator introduced in GM perilla gave rise to an amplicon 148 bp.