• Title/Summary/Keyword: F-N curve

Search Result 156, Processing Time 0.025 seconds

A Study on the Improvement of Fore-Body Shape Considering Breaking Wave Phenomena (쇄파현상을 고려한 선수형상개량법에 관한 연구)

  • K.J.,Kang;E.C.,Kim
    • Bulletin of the Society of Naval Architects of Korea
    • /
    • v.26 no.2
    • /
    • pp.1-12
    • /
    • 1989
  • This paper presents a method of minimizing the wave resistance components, due to the linear wave propagating to the far field and the breaking wave in the vicinity of the hull. This method consists of the linear optimization method for the linear wave resistance and the statistical optimization method for the breaking wave resistance through the analysis of the experimental data. For the purpose of the application, a wall-sided model with parabolic waterplane shape was selected as a basic hull form, and two modified hull forms with varied $C_p-curve$ of the fore-body were derived from the linear wave optimization method and the empirical method. The correlation between the linear wave resistance and the breaking wave resistance according to the $C_p-curve$ variation of the fore-body was investigated through the experimental and analytical results for the three hull forms. The fore-body shape optimized by the present method shows the reduction of the wave resistance by 47% comparing to the basic hull form at the design speed($F_n=0.26$).

  • PDF

Combination of 18F-Fluorodeoxyglucose PET/CT Radiomics and Clinical Features for Predicting Epidermal Growth Factor Receptor Mutations in Lung Adenocarcinoma

  • Shen Li;Yadi Li;Min Zhao;Pengyuan Wang;Jun Xin
    • Korean Journal of Radiology
    • /
    • v.23 no.9
    • /
    • pp.921-930
    • /
    • 2022
  • Objective: To identify epidermal growth factor receptor (EGFR) mutations in lung adenocarcinoma based on 18F-fluorodeoxyglucose (FDG) PET/CT radiomics and clinical features and to distinguish EGFR exon 19 deletion (19 del) and exon 21 L858R missense (21 L858R) mutations using FDG PET/CT radiomics. Materials and Methods: We retrospectively analyzed 179 patients with lung adenocarcinoma. They were randomly assigned to training (n = 125) and testing (n = 54) cohorts in a 7:3 ratio. A total of 2632 radiomics features were extracted from the tumor region of interest from the PET (1316) and CT (1316) images. Six PET/CT radiomics features that remained after the feature selection step were used to calculate the radiomics model score (rad-score). Subsequently, a combined clinical and radiomics model was constructed based on sex, smoking history, tumor diameter, and rad-score. The performance of the combined model in identifying EGFR mutations was assessed using a receiver operating characteristic (ROC) curve. Furthermore, in a subsample of 99 patients, a PET/CT radiomics model for distinguishing 19 del and 21 L858R EGFR mutational subtypes was established, and its performance was evaluated. Results: The area under the ROC curve (AUROC) and accuracy of the combined clinical and PET/CT radiomics models were 0.882 and 81.6%, respectively, in the training cohort and 0.837 and 74.1%, respectively, in the testing cohort. The AUROC and accuracy of the radiomics model for distinguishing between 19 del and 21 L858R EGFR mutational subtypes were 0.708 and 66.7%, respectively, in the training cohort and 0.652 and 56.7%, respectively, in the testing cohort. Conclusion: The combined clinical and PET/CT radiomics model could identify the EGFR mutational status in lung adenocarcinoma with moderate accuracy. However, distinguishing between EGFR 19 del and 21 L858R mutational subtypes was more challenging using PET/CT radiomics.

Prognostic Value of 18F-FDG PET/CT Radiomics in Extranodal Nasal-Type NK/T Cell Lymphoma

  • Yu Luo;Zhun Huang;Zihan Gao;Bingbing Wang;Yanwei Zhang;Yan Bai;Qingxia Wu;Meiyun Wang
    • Korean Journal of Radiology
    • /
    • v.25 no.2
    • /
    • pp.189-198
    • /
    • 2024
  • Objective: To investigate the prognostic utility of radiomics features extracted from 18F-fluorodeoxyglucose (FDG) PET/CT combined with clinical factors and metabolic parameters in predicting progression-free survival (PFS) and overall survival (OS) in individuals diagnosed with extranodal nasal-type NK/T cell lymphoma (ENKTCL). Materials and Methods: A total of 126 adults with ENKTCL who underwent 18F-FDG PET/CT examination before treatment were retrospectively included and randomly divided into training (n = 88) and validation cohorts (n = 38) at a ratio of 7:3. Least absolute shrinkage and selection operation Cox regression analysis was used to select the best radiomics features and calculate each patient's radiomics scores (RadPFS and RadOS). Kaplan-Meier curve and Log-rank test were used to compare survival between patient groups risk-stratified by the radiomics scores. Various models to predict PFS and OS were constructed, including clinical, metabolic, clinical + metabolic, and clinical + metabolic + radiomics models. The discriminative ability of each model was evaluated using Harrell's C index. The performance of each model in predicting PFS and OS for 1-, 3-, and 5-years was evaluated using the time-dependent receiver operating characteristic (ROC) curve. Results: Kaplan-Meier curve analysis demonstrated that the radiomics scores effectively identified high- and low-risk patients (all P < 0.05). Multivariable Cox analysis showed that the Ann Arbor stage, maximum standardized uptake value (SUVmax), and RadPFS were independent risk factors associated with PFS. Further, β2-microglobulin, Eastern Cooperative Oncology Group performance status score, SUVmax, and RadOS were independent risk factors for OS. The clinical + metabolic + radiomics model exhibited the greatest discriminative ability for both PFS (Harrell's C-index: 0.805 in the validation cohort) and OS (Harrell's C-index: 0.833 in the validation cohort). The time-dependent ROC analysis indicated that the clinical + metabolic + radiomics model had the best predictive performance. Conclusion: The PET/CT-based clinical + metabolic + radiomics model can enhance prognostication among patients with ENKTCL and may be a non-invasive and efficient risk stratification tool for clinical practice.

Diamond-like Carbon Tribological Endurance using an Energetic Approach

  • Alkelae, Fathia;Jun, Tea-Sung
    • Tribology and Lubricants
    • /
    • v.37 no.5
    • /
    • pp.179-188
    • /
    • 2021
  • Reputed for their low friction coefficient and wear protection effect, diamond-like carbon (DLC) materials are considered amongst the most important lubricant coatings for tribological applications. In this framework, this investigation aims to elucidate the effect of a few operating parameters, such as applied stress and sliding amplitude on the friction lifetime of DLC coatings. Fretting wear tests are conducted using a 12.7 mm radius counterpart of 52100 steel balls slid against a substrate of the same material coated with a 2 ㎛ thickness DLC. Approximately, 5 to 57 N force is applied, generating a maximum Hertzian contact pressure of 430 to 662 MPa, corresponding to the applied force. The coefficient of friction (CoF) generates three regimes, first a running-in period regime, followed by a steady-state evolution regime, and finally a progressive increase of the CoF reaching the steel CoF value, as an indicator of reaching the substrate. To track the wear scenario, interrupted tests are performed with analysis combining scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), 3D profilometer and micro-Raman spectroscopy. The results show two endurance values: one characterizing the coating failure (Nc1), and the other (Nc2) indicating the friction failure which is situated where the CoF reaches a threshold value of μth = 0.3 in the third regime. The Archard energy density factor is used to determine the two endurance values (Nc1, Nc2). Based on this approach, a master curve is established delimitating both the coating and the friction endurances.

A Study on the Energy Transfer of YAlO3:Tbx3+ using Decay Curves (YAlO3:Tbx3+에서 발광소멸 곡선을 이용한 에너지 전달에 관한 연구)

  • Kim, Gwang Chul;Choi, Jin Soo
    • Journal of the Semiconductor & Display Technology
    • /
    • v.14 no.1
    • /
    • pp.13-17
    • /
    • 2015
  • $YAlO_3:Tb{_x}^{3+}$ has been synthesized by a combustion process and the concentration x of Tb was varied from 0.001 and 0.05 mol% per mole of YAlO3. The energy transfer of $^5D_3{\rightarrow}^7F_6$(385nm) and $^5D_4{\rightarrow}^7F_5$(544nm) transitions on the $YAlO_3:Tb{_x}^{3+}$(x =0.001, 0.05) have been investigated by using decay curves. The energy transfer mechanism was explained by Inokuti and Hirayama model. The results of calculation and fitting showed that values of n are 6.11(x=0.01) and 6.13(x=0.005). These indicate that the energy transfer mechanism between $Tb^{3+}$ ions is dipole-dipole interaction.

Reliability analysis on fatigue Strength for Certification of Aircraft Composite Structures

  • Choi, Cheong Ho;Lee, Doo Jin;Jo, Jae Hyun;Bae, Sung Hwan;Lee, Myung Jik;Lee, Jong Ho
    • Journal of Aerospace System Engineering
    • /
    • v.15 no.2
    • /
    • pp.16-25
    • /
    • 2021
  • Reliability of fatigue strength on Aircraft Composites(GFRP) Structures was assessed in this paper. Fatigue strength of GFRP was used through the existing fatigue test data with Monte Carlo method. The Sa-Nf curve of composites fatigue strength was assumed as normal distribution and reliability was analyzed using SSIT model. Fatigue stress was designed IAW ASTM F3114-15 with special safety factor of Ssf=1.2~2.0. Reliability was calculated by analytic method and FORM. Sensitivity for the effect of mean and standard deviation of fatigue strength as well as fatigue stability was evaluated. This result can be usefully applied to reliability and fatigue design for composite structures of light weight aircraft.

A Study on Fatigue Behavior of Two-Span Fiber Reinforced Concrete Beam (강섬유 보강 철근콘크리트 2경간 연속보의 피로거동에 관한 연구)

  • Kwak, Kae-Hwan;Cho, Seon-Jeong;Seok, In-Soo
    • Journal of the Korea Concrete Institute
    • /
    • v.15 no.2
    • /
    • pp.163-172
    • /
    • 2003
  • As concrete structures are getting larger, higher, longer, and specialized, it is more required to develop steel fiber concrete and apply to the real world. In this research, it is aimed to have fatigue strength examined, varying the steel fiber content by 0%, 0.75%, 1.00%, 1.25%, by experimental study of Two-spans Beam with Steel Fibrous with repeated loads. The ultimate load and the initial load of flexural cracking were measured by static test. In addition, the load versus strain relation, load versus strain relation, load versus deflection relation, crack pattern and fracture mode by increasing weight was observed. On the other hand, the crack propagation and the modes of fracture according to cycle number and the relation of cycle loading to deflection relation and strain relation was observed by fatigue test. As the result of fatigue test, Two-spans Beam without Steel Fibrous was failed at 60~70% of the static ultimate strength and it could be concluded that fatigue strength to two million cycle was around 67.2% by S-N curve. On the other hand, that with Steel Fibrous was failed at 65~85% of the static ultimate strength and it could be concluded fatigue strength to two million cycle around 71.7%.

Evaluation of Purification Capacity of Vegetable Lactobacillus fermentum Culture System in Closed Environmental Waste Water (식물성 유산균 혼합물을 활용한 환경 폐수의 정화능력 평가)

  • Lee, Deuk Sik;Kim, Nam Kyun;Shim, Sooyong;Lee, Dong Jin;Yoon, Won Byong
    • Food Engineering Progress
    • /
    • v.15 no.1
    • /
    • pp.22-27
    • /
    • 2011
  • Changes in total nitrogen (T.N.) and total phosphate (T.P.) content in environmental waste water upon the reaction of biological purifying reagents were measured and the reaction rate was evaluated. The purification capacity of two biological purifying reagents composed of vegetable Lactobacillus fermentum (V.L.F.), Saccharomyces cerevisiae(S.C), and Bacillus subtilis(B.S.) were evaluated and compared with that of commercial water purification system operating by local government. After 18days of reaction, the mixture of V.L.F. and S.C. showed dramatic decrease of T.N.(36.21% of the initial value). The mixture of V.L.F., S.C., and B.S. showed faster reaction rate to decrease T.P. compared with that of the mixture of V.L.F. and S.C. The reaction constant of mixture of V.L.F. and S.C. was estimated to be 0.178 $day^{-1}$ by the curve fitting of the data of changes in T.N. during the reaction.

Trihalomethane Removal by a Fixed Bed Carbon Adsorber (고정층(固定層) 활성탄(活性炭)에 의한 Trihalomethane의 제거(除去))

  • Chung, Tai Hak;Chung, Jae Chul
    • KSCE Journal of Civil and Environmental Engineering Research
    • /
    • v.3 no.2
    • /
    • pp.87-95
    • /
    • 1983
  • Trihalomethane removal efficiency by a fixed bed carbon adsorber was a subject of this study. Along with laboratory scale column operations, a simple adsorption model was developed to predict removal efficiency. The adsorption model includes an overall mass transfer coefficient, K and Freundlich adsorption constants, $K_F$ and n. Simulation results showed that increasing K and $K_F$ or decreasing n would take more loading and prolong run time of the adsorption bed. Typical S-shaped breakthrough curves were obtained from the experiments. The operational results at $20^{\circ}C$ and $25^{\circ}C$ indicated that a moderate difference in water temperature would not affect the treatment efficiency significantly. The adsorption constants determined from the column operation and the model simulation were reasonably close to those obtained from the isotherm test. It may be concluded that trihalomethane can be removed successfully by a fixed bed carbon adsorber.

  • PDF

A Study on Propagation Behavior of Surface-Fatigue-Crack in the Mild Steel at Elevated Temperatures (軟鋼의 高溫 表面渡勞균열 成長擧動에 관한 硏究)

  • ;;北川英夫
    • Transactions of the Korean Society of Mechanical Engineers
    • /
    • v.7 no.4
    • /
    • pp.425-433
    • /
    • 1983
  • Fatigue tests by axial loading (R=0.1) were carried out to investigate fatigue crack growth properties of small surface cracks in mild steel at room temperature, 250.deg. C and 400.deg. C, by using flat specimens with a small artificial pit. All the data of the fatigue crack growth rate obtained in the present tests are determined as a function of the stress intensity factor range, so that the applicability of liner fracture mechanics to the fatigue crack growth of surface cracks at elevated temperatures is investigated and discussed in comparison with the data of type 304 stainless steel at room temperature and elevated temperature. The obtained results are as follows: 1) Relations of both surface fatigue crack length and its depth to cycle ratio fall within a narrow scatter band in spite of different stress levels. 2) The .DELTA. .sigma. .root. .pi. a-da/dN relation of surface fatigue crack growth at room temperature is independent of the stress level and can be plotted as a straight line at log-log diagram, but the relation at 400.deg. C depends partly on the stress level. 3) Relations of the fatigue crack growth into depth d(2b)/dN and is stress intensity factor range .DELTA. $K_{I}$, accounted for the aspect ratio variation, fall within a narrow scatter band for wide range of the applied stress levels. And .DELTA. $K_{I}$E-d(2b)/dN relations of mild steel at different stress level coincide relatively well with the data of type 304 stainless steel. 4) The value of aspect ratio obtained by a beach mark method and a temper coloring method approaches about 0.9 in common with crack growth and it is independent of stress level and temperatures. 5) The equi-crack length curve is parallel to S-N$_{f}$ curve at elevated temperatures.s.s.s.