• Journal of Veterinary Clinics
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• v.18 no.4
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• pp.429-433
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• 2001

Lymphoma is one of the most common malignant neoplasms of the dog. Little has been published on intraocular lymphoma in dogs. This report presents a 8-year-old neutered male mixed dog with a previous history on inflammatory debris on the anterior and posterior lens capsules, vitreal hemorrhage, generalized peri-pheral lymphadenopathy and a palpable mid-abodominal mass. History, clinical signs, radiography, cytology, histopathology and chemotherapeutic response confirmed multicentric lymphoma with secondary ocular infla-mmation. Intraocular lymphoma, the most common secondary neoplasm of the canine eye, may be the present-ing evidence of systemic disease. This report describes a dog that presented with ocular manifestations of multicentric lymphoma.

• Journal of Veterinary Clinics
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• v.32 no.2
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• pp.205-208
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• 2015

A 6-year old, neutered male, Maltese dog was presented in Veterinary Medical Teaching Hospital, Seoul National University. As hyphema and aqueous flare in the right eye were found, medical treatment for uveitis was started. Four months later, anterior displacement of dorsotemporal iris was observed. A mass originating from ciliary body of the right eye was revealed by ocular sonography. There was no evidence of metastasis on thoracic and abdominal radiographic imaging. Enucleation was performed on the right eye due to the enlargement of the mass and deteriorating uveitis. On histopathological evaluation, anterior uveal melanocytoma with chronic hemorrhage was confirmed. This case suggests adequate removal of intraocular neoplasm by enucleation can be curative in case of continuous hemorrhage or inflammation in the eye that cannot be controlled by non-surgical medications.

• Korean Journal of Veterinary Pathology
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• v.5 no.1
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• pp.1-4
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• 2001

Squamous cell carcinoma was diagnosed in a 4.5-year-old male African hedgehog (Atelerix albiventris). The patient was referred to Seoul National University, Veterinary Medical Teaching Hospital after 5 days history of left eye exophthalmos and corneal trauma. He had enlarged upper and lower jaw at the left part of the face and endophthalmitis of the left eye. On radiographic examinations, loss of bone density at the left zygomatic arch and sun-burst type periosteal reaction of left mandible with decreased bone density was noted. Histologically, the neoplastic mass consisted of markedly invasive, cords of nests of squamous epithelial cells. Intercellular bridges and keratin pearl formation were also noted.

• Journal of Yeungnam Medical Science
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• v.33 no.2
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• pp.142-145
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• 2016

Gastric cancer is the most common cancer in Korean males and can easily spread to distant organs such as the liver, lungs, brain, or bones. However, skin metastasis, particularly of the eye, is rare. Metastatic eyelid cancer is extremely rare; metastases from internal organs have not been reported so far. We recently experienced a patient with metastatic eyelid cancer from adenocarcinoma of the stomach. A 62-year-old female was admitted with a right upper eyelid mass and foreign body sensation. She had a history of stomach cancer of 3 years. She was treated by chemotherapy and radiotherapy for pathologic fracture. After receiving supportive care for 2 years, the mass appeared on her right pupil. Punch-biopsy of the mass was performed and histological examination revealed adenocarcinoma, the same as the initial histological result. We report this case with a review of related literature.

• Journal of Korean Neurosurgical Society
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• v.44 no.3
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• pp.156-158
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• 2008

Intraorbital hemorrhage is a rare clinical condition caused by orbital trauma, surgery around the orbit, intraorbital vascular abnormalities, and neoplasm. It was reported to occur spontaneously without any known causes and in association with orbital pseudotumor in a very few cases. A 59-year-old, female patient admitted with sudden onset of severe exophthalmos and pain on the left eye. Orbital CT and MR imaging suggested hemorrhage in the upper part of retrobulbar area of the left orbit. Cerebral angiography was taken to rule out any possible vascular abnormalities. On the left carotid cerebral angiography, the run-off of the distal ophthalmic artery was not seen and the engorgement of the supraophthalmic artery was noted. Systemic administration of corticosteroid did not improve the clinical status and craniectomy was done and retrobulbar hematoma was removed, and the clinical symptoms and signs were improved. Authors report a case of spontaneous intraorbital hemorrhage with the clinical features similar to those of orbital pseudotumor, requiring surgical decompression.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.17 no.3
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• pp.167-173
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• 2004

Strabismus is a misalignment of the eyes. It is divided into paralytic strabismus and non-paralytic strabismus. There are so many causes in paralytic strabismus, and the oculomotor nerve palsy is one of them. Many studies reported the etiology and clinical features of oculomotor nerve palsy. Common causes of oculomotor nerve palsy are idiopathic, vascula.; disease, aneurysm, head trauma, neoplasm and miscellaneous. Recently the proportion of traumatic cause has been increased, but the treatment is difficult as it used to be. In this case report, one case of traumatic oculomotor nerve palsy with zygomatic arch Fx and clavicle Fx were treated by herbal medicine and acupuncture. After Treatment, symptoms- ptosis, deviation of Lt. eye to downward & outward in primary position, diplopia, limited adduction & elevation & depression, dilated pupil without pupil reflex- were improved. There are so many hypothesises but no definite guide lines are established about the oriental medical treatment of oculomotor nerve palsy, so we expect the establishment of definite guide lines by further clinical studies.

• Journal of Veterinary Clinics
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• v.26 no.3
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• pp.290-297
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• 2009

A 5-year-old, castrated male Yorkshire Terrier with strabismus and exophthalmos of the right eye was referred to the Veterinary Medical Teaching Hospital, Chungnam National University. Radiography, ultrasonography(US), computed tomography(CT) and magnetic resonance imaging(MRI), demonstrated a well-circumscribed, locally calcified mass of the retrobulbar region with contiguous bone structures invaded. Surgical removal of the adnexa, globe, optic nerve and the incorporated orbital neoplasm was performed. Primary orbital meningioma was confirmed by histopathologic examination.

• Journal of Veterinary Clinics
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• v.39 no.3
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• pp.121-125
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• 2022

A 1-year-old neutered male Maltese dog was presented with a mass on the upper eyelid of the left eye (OS). A pinkish and alopecic mass was located in the nasal portion of the upper eyelid of OS. The mass was firmly attached to the eyelid and round-shaped with a diameter of 11 mm. Any spread to conjunctiva was not identified. On a cytological examination, cutaneous histiocytoma was confirmed, with the presence of small lymphocytes indicating later regression stage. The patient received no treatment and complete regression of the mass was verified 2 months later. The cytological examination was helpful for the diagnosis and staging of cutaneous histiocytoma. Canine eyelid histiocytoma can regress spontaneously, and thus medical or surgical treatment for removal should be considered carefully.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7567-7573
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• 2015

Background: Catastrophic effects of mustard gas as a chemical warfare agent have always been a major problem for those exposed to this agent. In this meta-analysis it was tried to evaluate carcinogenesis, ocular, cutaneous and respiratory complications of mustard gas exposure among Iranians who had been exposed to this agent during the Iran-Iraq war. Materials and Methods: In this meta-analysis, the required data were collected using keywords "mustard gas", "sulfur mustard", "cancer", "neoplasm", "respiratory complications", "ocular complications", "lung disease", "chronic complication", "eye", "skin", "cutaneous complication", "carcinogenesis" and their combination with keywords "Iran", "Iranian", "prevalence", "mortality" and their Farsi equivalent terms from the databases of SID, Iranmedex, Magiran, Pubmed, Science Direct, Google Search engine, Gray Literature and Reference of References. To determine the prevalence of each complication and perform meta-analysis, CMA: 2 (Comprehensive Meta-Analysis) software with a randomized model was used. Results: Of the 542 articles found, 7 national articles, consistent with the aims of this study were selected. Meta-analysis of seven papers revealed that cancer risk, especially cancer of the respiratory system was elevated, so that the relative risk (RR) of cancer role of mustard gas was inconsistent from 2/1 to 4 in this survey. Also prevalence of delayed skin disorders due to sulfur mustard was 94.6%, pulmonary complications 94.5% and ocular complications 89.9%. The incidence of various cancers in victims exposed to mustard gas was 1.7% worldwide where the rate was 2.2% in Iranian victims of the Iraq-Iran war. Conclusions: Based on present study the prevalence of delayed mustard gas related cutaneous, pulmonary and ocular complications is above 90% and risk of carcinogenesis is higher in comparison to worldwide statistics. This may suggest need for long-term and persistent follow-up and rehabilitation procedures for populations exposed to this agent.

• The Journal of Dong Guk Oriental Medicine
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• v.11
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• pp.1-40
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• 2008

The leukemia is caused by with abnormal changes of the hemotopoietic cell and in the various neoplasm group which occurs from lymph organization and the bone marrow occurs disrupts immigrates toward the blood of circumference and a hemotopoiesis and the arm discouragement royal tomb and is a disease which infiltrates with the organization. Western medical diagnosis and classification and presents eastern medicinal demonstration which is confronted in him about the leukemia, eastern medicinal diagnosis and treatment the clinical dissertation against precisely, saw and dissertation precisely tried about leukemia therapeutic effect of the herbal extract, last from conclusion like this dissertation precisely in the base which tries groped the direction of eastern medicinal treatment method research about the leukemia. Eastern medicine approach led about diagnosis and treatment of the leukemia and with leukemia treatment the medical herb which the eastern medicine possesses in development and room sacrifice an eastern medicine theory and the false eye presented the drug which is therapeutic possibility and they presented. The eastern medicine demonstration and therapeutic method is showing the therapeutic ratio which is effective about the leukemia. But according to the patient does a about prescription and therapeutic method differently and the room my composition is complicated and clinical day is consistent decides upon a reproducibility and a therapeutic ratio with difficult point of accumulation, with standardization of therapeutic method has the difficult point of supply. In treatment of the leukemia demonstrates a nature of a disease consequently with theory of eastern medicine and appropriately prescribes endeavors raises a therapeutic ratio and the medical herb and room proposal remedial value, under verifying reveals the clinical trial which is standardized leads and the medical herb and a room sacrifice and the verification and supply of effect and safety are necessary.