• 한국식품위생안전성학회지
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• 제34권4호
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• pp.374-379
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• 2019

본 연구에서는 대표적인 신선 잎채소류인 상추의 세척 단계에서 초음파 (37 kHz) 와 염소 (100~300 ppm) 의 병용처리 후 냉장 ~ 실온저장 ($10{\sim}25^{\circ}C$)에 따른 이 식품 중의 Salmonella Typhimurium의 성장예측모델을 개발하였다. 1 차 모델 개발을 위해 Gompertz 방정식을 활용하여 각기 다른 실험 조건에서의 S. Typhimurium의 생육도 (SGR 과 LT)를 조사했다. 본 방정식에 의한 1 차 모델 개발시 $R^2$가 0.92 이상으로 우수하게 나타났으며 저장온도가 낮을수록 초음파에 사용된 염소의 농도가 높을수록 SGR 값은 감소하였고 LT 값은 증가하였다. 이를 바탕으로 2 차 polynomial 모델을 개발하여 다양한 통계적 지표 ($R^2$, MSE, $A_f$ 및 $B_f$)를 통해 분석한 결과 개발된 모델의 적합성을 확인할 수 있었다. 따라서 개발된 모델이 초음파와 염소의 병용 세척에 따른 저장 중 상추에 대한 S. Typhimurium의 성장예측모델로 사용 가능하다고 판단되어지며, 신선 잎채소류에서의 식중독을 예방하고 미생물학적 위생관리기준을 설정하는데 기초자료로 활용될 수 있을 것으로 사료된다.

• 한국융합학회논문지
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• 제6권5호
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• pp.123-130
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• 2015

본 연구는 융합형 초음파 영상(ultrasound fusion imaging)을 이용하여 세 가지 교각운동(bridge exercise) 방법에 따른 몸통근육의 두께변화를 알아보기 위해 실시되었다. 건강한 성인 남녀 32명을 대상으로 교각 운동을 실시하는 동안 배속빗근(internal oblique), 배바깥빗근(external oblique), 배가로근(transverse abdominis) 그리고 뭇갈래근(multifidus)의 두께를 측정하였다. 연구결과, 세 가지 교각운동 방법에 따라 배속빗근, 배가로근, 뭇갈래근에서 유의한 두께변화를 보였다. 배가로근과 뭇갈래근은 exercise C(sling)에서 두께가 가장 증가하였고, exercise B(gym ball)와 exercise A(fixed support surface) 순으로 증가하였다. 배속빗근은 치료용 볼을 이용한 교각운동 시 두께가 가장 증가하였고, 슬링과 고정된 지지면 순으로 증가하였다. 특히, 슬링에서의 교각운동이 몸통 근육 두께증가에 가장 효과적인 방법이라고 사료된다. 최근까지, 몸통근육을 활성화 시키는 효과적인 방법으로 슬링에서의 교각운동이 많이 제안 되었지만, 융합형 초음파를 이용하여 관찰한 연구는 많지 않았다. 따라서 본 연구의 결과를 통해 임상에서 다양한 교각운동의 처방과 적용 시에 유용한 지침을 제공하고자 한다.

• 한국음향학회지
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• 제37권4호
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• pp.215-222
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• 2018

본 논문은 실시간 혈관내초음파 영상을 위한 후단부 시스템 개발과 성능 평가 결과에 관한 것이다. 개발한 후단부 시스템은 로직 사용량과 메모리 사용량을 최소화할 수 있는 효율적인 LUTs (Look-up Tables)을 사용하여 외부 메모리 없이 하나의 FPGA (Field Programmable Gate Array)만으로 시스템을 구성함으로써 시스템의 저비용, 소형화, 경량화가 가능하도록 설계하였다. 구현한 후단부 시스템의 정확도는 FPGA의 출력값과 VHDL (VHSIC Hardware Description Language) 코드를 MATLAB 프로그램을 사용하여 동일하게 구현하여 얻은 결과를 비교함으로써 검증하였다. 토끼 동맥을 이용한 ex-vivo 실험을 통하여 개발한 후단부 시스템이 실시간 혈관내초음파 영상에 적합함을 확인하였다.

• The Journal of Korean Physical Therapy
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• 제14권4호
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• pp.147-162
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• 2002

Transdermal permeation enhancer has been used to increased skin absorption. External control of drug release and skin absorption can also be achieved by iontophoresis or phonophoresis. However, because several problems with iontophoresis are that it has a risk to skin damage because of the change of pH and the increase of current density in applying it and that it can be applied only in the form of water solution, This study is to enhance drug permeation via skin following application of ultrasound. For this goal, in gel containing piroxicam, the degree of skin permeation in vitro and anti-inflammatory effect in in vivo were investigated. Permeation study using hairless mouse skin was performed at 37 $^{\circ}C$ using buffer saline as the receptor solution. The amount of piroxicam were quantified using a HPLC system consisting of solvent delivery system. Following adoption of ultrasound 1 MHZ, it showed relatively high permeation rate where it was compared with non treated by ultrasound. The influence of duty cycle having an effect on skin permeation rate was slight higher in the case of using pulsed mode. Skin permeation increase attended by intensity of ultrasound, the permeation of trice was accelerated at 2.0 W/$cm^{2}$ than 1.0 W/$cm^{2}$. The skin permeation of piroxicam was substantially influenced by ultrasound. Anti-inflammatory effects were determined using carrageenan-induced paw swelling method in SD rat. Paw swelling tests showed that pulsed phonophoresis group was more effective than control group and only gel application group. The conclusion of phonophoresis was found to improve significantly the skin permeation in vitro and the anti-inflammatory effect in vivo.

• 한국정밀공학회지
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• 제31권11호
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• pp.1051-1058
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• 2014

In this study, we investigated the improvement effect of obesity by treatment with a developed low frequency electrical stimulation system. Thirty female in their 20's as an experiment subjects divided 3 groups(control, commercialized device, developed device) were treated with electrical stimulation on abdomen for 4 weeks. The body weight, body mass index(BMI), waist-hip ratio(WHR), muscle strength, muscle(transverse abdominis(TrA), internal obliquus abdominis(IO), external obliquus abdominis(EO)), fat thickness and abdominal surface temperature were measured by electromyogram(EMG), ultrasound and digital infrared thermal image(DITI). In the result, the body weight and BMI were decreased. Subcutaneous abdominal fat were significantly reduced after 4 weeks. The muscle strength and TrA muscle thickness was increased 13.2%(p<0.05), and 35.5%, respectively. The fat thickness showed decrease in abdomen (p<0.05). Infrared measurement on abdominal surface temperature as a parameter of improvement in blood circulation was significantly increased(p<0.05). Therefore, the low frequency stimulation showed positive effects on parameters of the obesity improvement.

• 한국수정란이식학회지
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• 제30권4호
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• pp.335-340
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• 2015

The objective of this study was to evaluate the initial detection time and development of the fetal genital structures using ultrasound in twelve pregnant small bitches. The initial detection time of the fetal genital structures was as follows: genital tubercle at days 32.6; os penis at days 45.2; labia at days 45.7; scrotum at days 47.5. Ultrasonograms of fetal genital structure according to gestational stage were as follows: Undifferentiated stage (before day 35), the genital tubercle was observed to have a small elevation and just a hyper-echogenic structure in the midline between the umbilical cord and the tail in male and female fetus. Migration stage (between day 35~45), the genital tubercle was observed as a hyper-echogenic, bilobular, oval shaped and the genital tubercle began to migrate from the initial position toward the umbilical cord in males, and toward the tail in females. Differentiated stage (after day 46), the penis and os penis were observed to stand out in the abdominal wall and the scrotum was observed toward the perineal region in male fetuses. The labia was detected at the base of the tail in female fetuses. These results indicate that ultrasound of fetal genital structures could be useful for fetal gender determination and a completely prepartum evaluation of the canine fetus.

• 대한방사선기술학회지:방사선기술과학
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• 제39권2호
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• pp.157-161
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• 2016

본 연구에서는 자체 제작한 3종의 초음파 TM 팬텀의 음향학적 특성 및 온도 민감도를 측정하였으며, 초음파 영상학적 특성을 관찰, 평가하였다. TM 팬텀은 폴리우레탄을 주재료로 국제전기표준회의(International Electronical Committee, IEC) 기준안에 따라 제작하였으며 외부 온도 변화 따른 초음파 영상학적 특성은 $22^{\circ}C$ 이하에서 온도감소에 따라 휘도 및 영상투과심도가 비례하여 감소하는 것이 확인되었다. 본 연구를 통하여 산란재 특성이 상이한 TM 팬텀을 제작하는 기초자료를 제공하였으며, TM 팬텀의 사용 온도는 $22^{\circ}C$ 이상에서 사용하는 것이 적합한 것으로 판단되었다.

• 대한물리의학회지
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• 제7권4호
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• pp.533-539
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• 2012

PURPOSE: The purpose of this study was to investigate the effect of pelvic floor muscle contraction with image feedback on Abdominal muscle thickness. METHODS: Twenty three adults participated in this study. Abdominal muscle thickness was measured by ultrasound in three condition(rest, pelvic floor muscle contraction, pelvic floor muscle contraction with image feedback). Subjects was contraction pelvic floor muscle by general method. And ultrasound(convex probe, 3.5MHz) was used to image feedback for selective pelvic floor muscle contraction. One-way ANOVA was used to compare abdominal muscle thickness in three condition. RESULTS: There was no significant difference in external oblique(p=.514) and internal oblique muscle(p=.250) thickness by three condition. There was significant difference in transverse abdominis thickness by three condition (Transverse abdominis thickness was highest while Pelvic floor muscle contraction than pelvic floor muscle contraction with image feedback and rest.)(p=.000). CONCLUSION: This study shows that pelvic floor muscle contraction with image feedback increase the thickness of transverse abdominis lesser than general pelvic floor muscle contraction.

• 대한의용생체공학회:의공학회지
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• 제27권3호
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• pp.117-124
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• 2006

Recently, active research has been going on to measure the elastic modulus of human soft tissue with medical ultrasound imaging systems for the purpose of diagnosing cancers or tumors which have been difficult to detect with conventional B-mode imaging techniques. In this paper, a real-time ultrasonic elasticity imaging system is implemented in software on a Pentium processor-based ultrasonic diagnostic imaging system. Soft tissue is subjected to external vibration, and the resulting tissue displacements change the phase of received echoes, which is in turn used to estimate tissue elasticity. It was confirmed from experiment with a phantom that the implemented elasticity imaging system could differentiate between soft and hard regions, where the latter is twice harder than the former, while operating at an adequate frame rate of 20 frames/s.

• 대한물리의학회지
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• 제8권3호
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• pp.379-385
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• 2013

PURPOSE: This study is research about deep trunk muscles (DTM) that is important and serve to control the movement of the trunk to provide stability during movement for human. In this study, trying to prove a change of DTM of aging in the ultrasound image. METHODS: We measured via an ultrasound image during rest and contraction of DTM in 42 young and 48 old people, and then we measured the change of thickness and symmetry. RESULTS: Symmetry showed a significant difference only external oblique (EO) in the young(p<.05). In the elderly, it was found that ratio of contraction was greater transverse abdominis than EO. CONCLUSION: I considered it could lead to improvement of activity of daily life by applying intervention for recovery of motor control of TrA for the elderly in clinical practice.