• Development and Reproduction
• /
• v.19 no.2
• /
• pp.69-77
• /
• 2015

Cell-cell direct communication through channel-forming molecules, connexin (Cx), is essential for a tissue to exchange signaling molecules between neighboring cells and establish unique functional characteristics during postnatal development. The corpus epididymis is a well-known androgen-responsive tissue and involves in proper sperm maturation. In the present research, it was attempted to determine if expression of Cx isoforms in the corpus epididymis in the adult is modulated by exposure to estrogenic or anti-androgenic compound during the early postnatal period. The neonatal male rats at 7 days of age were subcutaneously injected by estradiol benzoate (EB) at low-dose ($0.015{\mu}g/kg$ body weight) or high-dose ($1.5{\mu}g/kg$ body weight) or flutamide (Flu) at low-dose ($500{\mu}g/kg$ body weight) or high-dose (50 mg/kg body weight). The corpus epididymis collected at 4 months of age was subjected to evaluate expressional changes of Cx isoforms by quantitative real-time PCR. Treatment of low-dose EB resulted in increases of Cx32, Cx37, and Cx45 transcript levels, while exposure to high-dose EB decreased expression of Cx26, Cx30.3, Cx31, Cx31.1, Cx32, Cx40, Cx43, and Cx45. Treatments of Flu caused significant decreases of expression of all examined Cx isoforms, except Cx37 and Cx43 shown no expressional change with high-dose Flu treatment. These findings imply that expression of most Cx isoforms present in the corpus epididymis would be transcriptionally regulated by actions of androgen and/or estrogen during postnatal period.

• Journal of Digital Convergence
• /
• v.14 no.7
• /
• pp.355-362
• /
• 2016

This research analyzed 'esquisse', that is one of among the visual representation tools of designers in design-thinking process. They were classified into five different types(M, N, O, P, Q) and categorized about preferred type of brain dominance area based on Ned Herrmann's 'Brain 4 division theory'. By contrasting and analyzing five types of sketch tendencies and brain tendencies through Structural left -brain type(M), Emotional limbic-brain type(N), Visual right-brain type(O), Plane expressional right-brain type(P) and Text expressional right-brain type(Q), it was deduced that which utilization the designer with each brain type with various Styles and characteristics shows internally in the design thinking process can be analyzed.

• Development and Reproduction
• /
• v.23 no.3
• /
• pp.213-221
• /
• 2019

The epididymal fat of mouse is a part of visceral fat deposit and is divided into the distal or proximal part based on its histochemical characteristics. Even though the formation of the epididymal fat pad begins before the birth, a detailed adipogenic procedure of the epididymal fat has not been revealed. The epididymal fat pad becomes enlarged and expended with age, and expressional changes of numerous genes are associated with the maturation of fat tissues. In the present research, expressional patterns of adipose tissue-related genes in the distal epididymal fat of mouse at 2, 5, 8, and 12 months of postnatal age were determined by a quantitative real-time polymerase chain reaction (PCR) analysis. The lowest transcript levels of fatty acid binding protein 4 (Fabp4), lipoprotein lipase (Lpl), delta like non-canonical Notch ligand 1 (Dlk1), peroxisome proliferator-activated receptor gamma (Pparg), leptin (Lep), adiponectin (Adipoq), and resistin (Retn) were detected at 2 months of age, except fatty acid synthase (Fasn) showing the lowest level at 5 months of age. Even though expression of Lep and Fabp4 were gradually increased until 12 months of age, significant increases of Pparg and Adipoq transcript levels were continued until 8 months of age. The transcript levels of Lpl, Rent, Dlk1, and Fasn were significantly increased at 8 months of age, compared with those at 2 months of age. The current findings suggest that the expansion of the distal epididymal fat of mouse during postnatal period would be companied with differential expression of various adipocyte-associated molecules.

• Fashion & Textile Research Journal
• /
• v.17 no.5
• /
• pp.691-703
• /
• 2015

Indeterminacy maintains that the simultaneous measurement of object location and speed is theoretically impossible. This study present indeterminacy as a theoretic tool to interpret a variety of expression characteristics that seem disorderly in recent fashion illustrations; in addition, it analyzes the characteristics and meaning of indeterminacy as expressed in fashion illustrations. This study reviews concepts and related theories on indeterminacy to examine characteristics of indeterminacy expressed in the arts and fashion; subsequently, indeterminacy characteristics found in fashion illustrations are analyzed. In expressing the fashion figure, indeterminacy finds expression in a distorted figure transformations that include a hybridized combination of heterogeneous forms that dismantle and reconstruct the human body. The hybridized body of combined machines, animals and plants indicates an indeterminate body endlessly transforming itself. Indeterminate space expression finds expression in space expression by projection with the overlapping and juxtaposition of irrelevant constituent elements as well as a space expression from the insertion of unexpected images. An unclarified inconclusive open space provides space with fluidity, causes space expansion and conveys inconclusive meaning. Indeterminate expressions found in fashion illustrations reveal the ambiguity and complexity of a post-modern society with polysemous aesthetic values and the expanded visual concepts of fashion illustrations.

• Korean Institute of Interior Design Journal
• /
• v.20 no.6
• /
• pp.135-144
• /
• 2011

This study starts from the question if the characteristic of existing conventional site-specificity can be applied to the modern city space in information media era as it is. The evolution and spread of media technology acted as the catalyst which establishes the identity of an individual and promotes the social sense of belonging as the new type of community member as well as expanded the communication territory of man. Moreover, as the perfect merge of third dimensional space with second dimensional media was accomplished, the meaning of city as the place is getting changed and extended to city space as the information platform which integrates and intermediates the various information composing city. Hereupon, this study is willing to analyze the limits which the characteristics of physical, active and meaningful elements which are the forming primary factors in the existing place theory have and establish the new meaning of city as the place through the case studies which are applied by the characteristics of hyper spacio-temporal, mobility and polysemy as the characteristics transformed by information platformization of city space.

• Archives of design research
• /
• v.16 no.1
• /
• pp.159-168
• /
• 2003

Modern fashion shop is changed by the changing of fashion style. And as purchasing pattern is changed to consuming pattern which has strong individuality, functions as space which reflet characteristics of products and consumers in order to present sensitive and individual image are also required, besides conventional concept as space which simply focused on sale. Meanwhile, in the 1980's, the fashion presented retro mood modernly by popularization of post-modernism and introduced minimalism that is one of the anti-cultures in the 1960's. Recently minimalistic trends which are expressed by various attempts and a new point of view are introduced to the fashion shop by interior designer. Therefore, in this study, minimalistic characteristics which appear in the composition of interior space of the modern fashion shop are researched by theoretical consideration and analysis of examples and consistent direction of fashion shop is presented.

• The Research Journal of the Costume Culture
• /
• v.25 no.3
• /
• pp.315-326
• /
• 2017

The purpose of this study is to investigate the design methods and characteristics of papercraft fashion from 2001 to 2015. The study has been conducted through theoretical research and case study. Overall, types of papercraft expressions are classified into the following four categories: narrative papercraft fashion, organic papercraft fashion, variable papercraft fashion, and recycling papercraft fashion. The characteristics and aspects of each type of papercraft is described below. First, narrative papercraft fashion expresses as factual description of the natural environment. These works convey fantastic image by showing fairy tale animals or plants using paper folding or cutting. Second, organic papercraft fashion creates a futuristic shape by expressing organic parts in nature. Also, it often depicts future-oriented images by repeatedly representing organic shapes using uniform patterns in nature. Third, variable papercraft fashion expresses a variety of changing shapes through a flexible design based on the style of wearing. This variation may be accomplished through changeable dress connected to human gestures. Variable papercraft represents play-fulness, which conveys enjoyment to the wearer and the audience. Fourth, recycling papercraft fashion uses paper materials of the past, and recreates them into artworks through handicraft techniques. Recycling papercraft conveys high value added fashion by dissolving the material into pulp.

• Journal of the Korea Furniture Society
• /
• v.27 no.1
• /
• pp.1-7
• /
• 2016

De Stijl in order to began in the Netherlands in 1917 is an art movement that becomes the theoretical background of modernism design was the foundation geometric abstraction. Steel design for that they offered a new paradigm at that time art, in various fields such as industrial design is still applied, especially works of De Stijl in the design area of urniture it became the beginning of the modern furniture. The starting point of this study is to analyze the two-dimensional representation characteristics to understand the background of the formation with the basic concepts of De Stijl. Therefore the generation of the surface to be displayed in the work of De Stijl and to analyze the divided element, and not if learn their expression characteristics. Also the line and the plane of the two-dimensional modeling properties of De Stijl, after described colors, and studied the characteristics of De Stjil writers for typical analyzes the moldability shown in their work, which based on, we try to present a new representation technique.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.32 no.2
• /
• pp.307-318
• /
• 2008

Recently, the environmental problems have surfaced as serious social issues. More people become aware of the environments and seek for new kinds of lifestyle Lohas. The purpose of this study was to investigate the expressional characteristics of Lohas fashion design in ready-to-wear collection from 2000 till 2005. In the study, green design which was the base of Lohas fashion, was first examined, which was followed by an analysis of Lohas styles to understand the green design-oriented characteristics of Lohas fashion in the current fashion trends. The findings were as follows: First, the lifestyle of Lohas values 'environment-friendliness', 'sustainability', 'importance of health' and 'sensitivity'. Second, the distinguishing features of Lohas lifestyle categorize the Lohas fashion into five different looks: 'Lohas Natural Look', 'Lohas Vintage Look', 'Lohas Redesign Look', 'Lohas Multi look', and 'Lohas Wellness Look'. This study set out to provide useful results to be used as the basic data in studying design and related areas where they would develop fashion products for the consumers with the latest tastes as well as to promote environment protection.

• Proceedings of the Korean Institute of Interior Design Conference
• /
• 2007.05a
• /
• pp.260-263
• /
• 2007

A church architecture which has an important meaning as a place which is for worship God, relationship, education, evangelism, service and formative meaning that express as a specific form. It has been changed by age or changes of theology, also its structure and form has been changed so as to change of a rutual. the church architecture that has been authorized as a architecture which is a representation of the age does not represent the age and it has weaknesses for expression of unique identification church has. Also, because it is lacking thoughts about regional viewpoint, it loses the characteristic of regional "landmark" like the past. In addition, a place of worship has been changed materiality of space like auditorium or seats so as to change of consciousness of worship, and it is exposed problems of expression of identification. Therefore the church architecture of twenty first centry needs to holy and be able to deliver their new standards and needs that fit original purpose of church for users.