• Journal of radiological science and technology
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• v.40 no.1
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• pp.49-55
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• 2017

In the case of nuclear medicine practitioners in medical institutions, a wide range of exposure dose to individual workers can be found, depending on the type of source, the amount of radioactivity, and the use of shielding devices in handling radioactive isotopes. In this regard, this study evaluated the organ dose on practitioners as well as the dose reduction effect of the L-block shielding device in handling the diagnostic radiation source through the simulation based on the Monte Carlo method. As a result, the distribution of organ dose was found to be higher as the position of the radiation source was closer to the handling position of a practitioner, and the effective dose distribution was different according to the ICRP tissue weight. Furthermore, the dose reduction effect according to the L-block thickness tended to decrease, which showed the exponential distribution, as the shielding thickness increased. The dose reduction effect according to each radiation source showed a low shielding effect in proportion to the emitted gamma ray energy level.

• Journal of Radiation Protection and Research
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• v.43 no.2
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• pp.39-49
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• 2018

Background: A model to assess the activity concentration of agricultural products and the public ingestion dose as result of a nuclear accident is necessarily required to manage the contaminated agricultural systems by the accident, or to estimate the effects of chronic exposure due to food ingestion at a Level 3 PSA. Materials and Methods: A dynamic compartment model, which is composed of three sub-modules, namely, an agricultural plant contamination assessment model, an animal product contamination assessment model, and an ingestion dose assessment model has been developed based on Korean farming characteristics such as the growth characteristics of rice and stockbreeding. Results and Discussion: The application study showed that the present model can predict well the characteristics of the activity concentration for agricultural products and ingestion dose depending on the deposition date. Conclusion: The present model is very useful to predict the radioactivity concentration of agricultural foodstuffs and public ingestion dose as consequence of a nuclear accident. Consequently, it is expected to be used effectively as a module for the ingestion dose calculation of the Korean agricultural contamination management system as well as the Level 3 PSA code, which is currently being developed.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.12 no.2
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• pp.171-178
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• 2014

After the expiration of operating license of a plant, all infrastructures within the plant must be safely dismantled to the point that it no longer requires measures for radiation protection. Despite the fact that Kori 1 and Wolsong 1 are close to the expiration of their operating license, sufficient technologies for radiological characterization, decontamination and dismantling is still under development. The purpose of this study is to develop one of methods for radiological inventory assessment on measuring object by using direct measure of large component with In-Situ measurement technique. Radiological inventory was assessed by analyzing nuclide using portable gamma spectroscopy without dismantling reactor head, and the result of direct measurement was supplemented by performing indirect measurement. Radiochemical analysis were performed on surface contamination samples as well. During the study, radiological inventory of reactor vessel calculated expanding the result. Based on the result and the radioactivity variation of each radionuclides time frame for decommissioning can be decided. Thus, it is expected that during the decommissioning of plants, the result of this study will contribute to the reduction of radiation exposure to workers.

• The Korean Journal of Nuclear Medicine Technology
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• v.18 no.1
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• pp.98-103
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• 2014

Purpose: The effective half life of I-131 is useful to calculate radiation dose, period of hospitalization, and exposure dose of surrounding people from patient. However, it is difficult to measure. This study estimates the effective half life in whole body and thyroid in using of value of residual radioactivity obtained from the early and delay images of Dual time I-131 whole body scan. Also, the correlations between the effective half life and serum creatinine, GFR, and administration dose were investigated in this study. Materials and Methods: The targets were 50 patients administration high dose of I-131 from February to August in 2013, having normal range of serum creatinine and over $30{\mu}IU/mL$ of TSH levels. After administration radioactive I-131, the early scan in the 3rd day and the delay scan in the 5-6th days were performed. To measure the residual radioactivity in the whole body and thyroid, ROI was set and then background radioactivity was corrected to estimate. The effective half life was estimated by calculating the ratio of measured values between the early and delay images. To compare the effective half lives of the whole body and thyroid, it was analyzed by Independent t-test, and each correlation of the effective half life, GFR, serum creatinine, and the dose of administration were analyzed by calculating the pearson's correlation coefficient. All of the analysis were determined to be statistically significant when P<0.05. Results: The effective half life of the whole body was $17.06{\pm}5.50$ hours and of the thyroid was $17.22{\pm}5.41$ hours. The two effective half life did not show significant difference (P=0.887). As the value of GFR was increased, the effective half life of whole body (r=-0.407, P=0.003) and of thyroid (r=-0.473, P=0.001) were significantly decreased; as the value of serum creatinine was increased, the effective half life of whole body (r=0.309, P=0.029) and of thyroid (r=0.371, P=0.008) were significantly increased. In the administration dose, effective half life did not have correlations. Conclusion: The effective half life of I-131 of patients treated for their thyroids were estimated only by using the images of Dual time I-131 whole body scan. Also, the correlations with the effective life, GFR, and serum creatinine were examined. This study might be utilized for a study on optimization for the period of hospitalization of patients treated by high dose of I-131 and on evaluation for internal absorbed dose of MIRD schema in application of the effective half life.

• Journal of Radiation Protection and Research
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• v.22 no.3
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• pp.183-193
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• 1997

The amount and kinds of radionuclide contained in waste volume should be known to prepare for occupational exposure management, perform safety assessment and finally to license a repository. Although the volume of filters and resins are small, activities of them comprise most of the radioactivity that made during power generation. This study aims at developing a method of estimating the radionuclide accumulation at the filters and resins of coolant systems. In this study, accumulated amount of radionuclides is estimated by a computer program which makes use of instantaneous decontamination factor, DF, instead of average DF. A FORTRAN program was developed for the estimation. Data from in-plant source-term measurements at Rancho-Seco nuclear power plant in the United States are employed for verification of the estimating method. And experimental data are employed, too. The instantaneous-DF-method showed smaller error than the average-DF-method. Accumulated amount of radionuclides can be calculated with only the DF and the radionuclide concentration, which are measured periodically according to the operating guide. However, especially, when the operating condition of nuclear power plant changes rapidly, the measuring term of DF and radionuclide should be shortened to ensure the accurate estimation.

• Archives of Pharmacal Research
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• v.22 no.5
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• pp.474-478
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• 1999

Modulation of unscheduled DNA synthesis by dehydroepiandrosterone (DHEA) after exposure to various chemical carcinogens was investigated in the primary rat hepatocytes. Unscheduled DNA synthesis was induced by treatment of such direct acting carcinogens as methly methanesulfonate (MMS) and ethyl methanesulfonate (EMS) or procarcinogens including benzo(a)pyrene (BaP) and 7, 12-dimethylbenz(a)anthracene (DMBA). Unscheduled DNA synthesis was determined by measuring [methyl-3H]thymidine radioactivity incorporated into nuclear DNA of hepatocytes treated with carcinogens in the presence or absence of DHEA. Hydroxyurea $(5{\times}10^{-3} M)$was added to growth medium to selectively suppress normal replication. DHEA at concentrations ranging from $(1{\times}10^{-6} M)$ to$(5{\times}10^{-4} M)$ did not significantly inhibit unscheduled DNA synthesis induced by either MMS $(1{\times}10^{-4} M)$ or EMS $(1{\times}10^{-2} M)$. In contrast, DHEA-significantly inhibited unscheduled DNA synthesis induced by BaP $(6.5{\times}10^{-5} M)$ and DMBA.$(2{\times}10^{-5} M)$. DHEA-induced hepatotoxicity in rats was examined using lactate dehydrogenase (LDH) release as an indicator of cytotoxicity. DHEA exhibit no significant increase in LDH release compared with the control at 18 h. These data suggest that nontoxic concentration of DHEA does not affect the DNA excision repair process, but it probably influence the enzymatic system responsible for the metabolic activation of procarcinogens and thereby decreases the amount of the effective DNA adducts formed by the ultimate reactive carcinogenic species.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.6
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• pp.123-128
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• 2020

In this paper, we presents a new cone beam computerized tomography (CBCT) system for the reconstruction of 3 dimensional dynamic images. The system using cone beam has less the exposure of radioactivity than fan beam, relatively. In the system, the reconstruction 3-D image is reconstructed with the radiation angle of X-ray in the image processing unit and transmitted to the monitor. And in the image processing unit, the Three Pass Shear Matrices, a kind of Rotation-based method, is applied to reconstruct 3D image because it has less transcendental functions than the one-pass shear matrix to decrease a time of calculations for the reconstruction 3-D image in the processor. The new system is able to get 3~5 3-D images a second, reconstruct the 3-D dynamic images in real time. And we showed the Rotation-based method was good rather than existing reconstruction technique for 3D images, also found weakness and a solution for it.

• The Journal of the Acoustical Society of Korea
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• v.28 no.4
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• pp.370-374
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• 2009

In this paper, we presents a new cone beam computerized tomography (CB CT) system for the reconstruction of 3 dimensional dynamic images. The system using cone beam has less the exposure of radioactivity than fan beam, relatively. In the system, the reconstruction 3-D image is reconstructed with the radiation angle of X-ray in the image processing unit and transmitted to the monitor. And in the image processing unit, the Three Pass Shear Matrices, a kind of Rotation-based method, is applied to reconstruct 3D image because it has less transcendental functions than the one-pass shear matrix to decrease a time of calculations for the reconstruction 3-D image in the processor. The new system is able to get 3~5 3-D images a second, reconstruct the 3-D dynamic images in real time.

• Journal of the Korean Society of Radiology
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• v.11 no.6
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• pp.531-538
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• 2017

Agricultural products produced in the agricultural area around the nuclear power plant are radioactive contamination, which can cause radioactive contamination to the human body. The purpose of this study was to investigate the limit of the radioactivity concentration $^{90}Sr$ for the internal exposure dose evaluation by ingesting the agricultural products collected around the nuclear power plant. The results of the gamma-isotope element analysis were freshly <0.0166-0.0336 Bq / kg for all samples and for artificial radionuclides not detected, and fresh <0.00586-0.0421 Bq / kg for Chinese cabbage, The freshness was 0.106 Bq / kg, and the freshness was 0.0114-0.0901 Bq / kg. 0.0177%, 0.0222%, 0.0376% and 0.00243%, respectively, for Chinese cabbages and large roots, which is lower than the legal standard value of $1mSv/yr{\cdot}man%$. It is considered that the formulas need to be broadly evaluated for the foods consumed by children and adults, taking into consideration the age of the food and the diet

• Asian-Australasian Journal of Animal Sciences
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• v.16 no.12
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• pp.1822-1829
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• 2003

Porcine colostrum and milk were separated into the acid-soluble and casein fractions by acidification followed by centrifuge. The acid-soluble fraction of porcine colostrum was further separated by liquid chromatography and anisotropic membrane filtration. Trypsin and chymotrypsin inhibitory capacity in porcine colostrum, milk and their components was determined by incubating bovine trypsin or chymotrypsin in a medium containing their corresponding substrates with or without addition of various amounts of porcine colostrum, porcine milk or their components. The inhibition of insulin-like growth factor I (IGF-I) and epidermal growth factor (EGF) degradation in pig small intestinal contents by porcine colostrum was measured by incubating iodinated IGF-I or EGF with the intestinal contents with or without addition of porcine colostrum. Degradation of labeled IGF-I or EGF was determined by monitoring the generation of radioactivity soluble in 30% trichloroacetic acid (TCA). The results showed that porcine colostrum had high levels of trypsin and chymotrypsin inhibitory activity and increased the stability of IGF-I and EGF in pig intestinal contents. The inhibitory activity declined rapidly during lactation. It was also found that trypsin and chymotrypsin inhibitory activity and the inhibition on IGF-I and EGF degradation in the acid-soluble fraction were higher than that in the casein fraction. Heat-resistance study indicated that trypsin inhibitors in porcine colostrum survived heat treatments of $100^{\circ}C$ water bath for up to 10 min, but exposure to boiling water bath for 30 min significantly decreased the inhibitory activity. Compared with the trypsin inhibitors, the chymotrypsin inhibitors were more heatsensitive. Separation of the acid-soluble fraction of porcine colostrum by liquid chromatography and anisotropic membrane filtration revealed that the trypsin and chymotrypsin inhibitory capacity was mainly due to a group of small proteins with molecular weight of 10,000-50,000. In conclusion, the present study confirmed the existence of high levels of protease inhibitors in porcine colostrum, and the inhibition of porcine colostrum on degradation of milk-borne growth factors in the pig small intestinal tract was demonstrated for the first time.