• Title/Summary/Keyword: Exposure to Hazard Factors

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Cancer Risks among Welders and Occasional Welders in a National Population-Based Cohort Study: Canadian Census Health and Environmental Cohort

  • MacLeod, Jill S.;Harris, M. Anne;Tjepkema, Michael;Peters, Paul A.;Demers, Paul A.
    • Safety and Health at Work
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    • v.8 no.3
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    • pp.258-266
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    • 2017
  • Background: Welders are exposed to many known and suspected carcinogens. An excess lung cancer risk among welders is well established, but whether this is attributable to welding fumes is unclear. Excess risks of other cancers have been suggested, but not established. We investigated welding cancer risks in the population-based Canadian Census Health and Environmental Cohort. Methods: Among 1.1 million male workers, 12,845 welders were identified using Standard Occupational Classification codes and followed through retrospective linkage of 1991 Canadian Long Form Census and Canadian Cancer Registry (1992-2010) records. Hazard ratios (HRs) were calculated using Cox proportional hazards models based on estimated risks of lung cancer, mesothelioma, and nasal, brain, stomach, kidney, and bladder cancers, and ocular melanoma. Lung cancer histological subtypes and risks by industry group and for occasional welders were examined. Some analyses restricted comparisons to blue-collar workers to minimize effects of potential confounders. Results: Among welders, elevated risks were observed for lung cancer [HR: 1.16, 95% confidence interval (CI): 1.03-1.31], mesothelioma (HR: 1.78, 95% CI: 1.01-3.18), bladder cancer (HR: 1.40, 95% CI: 1.15-1.70), and kidney cancer (HR: 1.30, 95% CI: 1.01-1.67). When restricted to blue-collar workers, lung cancer and mesothelioma risks were attenuated, while bladder and kidney cancer risks increased. Conclusion: Excess risks of lung cancer and mesothelioma may be partly attributable to factors including smoking and asbestos. Welding-specific exposures may increase bladder and kidney cancer risks, and particular sources of exposure should be investigated. Studies that are able to disentangle welding effects from smoking and asbestos exposure are needed.

Risk Assessment by Toluene Source Emission Model in Indoor Environments of New Houses (신축 주택의 톨루엔 발생량 모델을 이용한 건강위해성 평가)

  • Kim, Young-Hee;Yang, Won-Ho;Son, Bu-Soon
    • Journal of Environmental Health Sciences
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    • v.32 no.5 s.92
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    • pp.398-403
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    • 2006
  • Indoor air quality can be affected by indoor sources, ventilation, decay and outdoor levels. Understanding the effectiveness of indoor air quality control depends on knowledge of the characteristics of air pollutants in indoor air, especially their quantities and persistence, and the relevance of indoor sources to these factors. Toluene within new and established houses has been determined and factors significant to its presence have been identified. A total of 30 selected houses in Seoul, Asan and Daegu areas that were constructed within 4 years and over 4 years of construction were measured the concentration of toluene from July to September in 2004. Toluene emission decay of double-exponential model exhibited good fit of $Y=276.37e^{-1.21x}(R^{2}=0.34,\;P=0.06)$ for 2 years and then $Y=51.54e^{-0.11x}(R^{2}=0.40,\;P=0.0)$ from 23 years in new houses. In case of living in new houses, noncarcinogenic health effects of exposure to toluene was 1.38 of hazard quotient (HQ) comparing to toluene reference dose of 0.13 mg/kg-day.

Attitude of the Korean dentists towards radiation safety and selection criteria

  • Lee, Byung-Do;Ludlow, John B.
    • Imaging Science in Dentistry
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    • v.43 no.3
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    • pp.179-184
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    • 2013
  • Purpose: X-ray exposure should be clinically justified and each exposure should be expected to give patients benefits. Since dental radiographic examination is one of the most frequent radiological procedures, radiation hazard becomes an important public health concern. The purpose of this study was to investigate the attitude of Korean dentists about radiation safety and use of criteria for selecting the frequency and type of radiographic examinations. Materials and Methods: The study included 267 Korean dentists. Five questions related to radiation safety were asked of each of them. These questions were about factors associated with radiation protection of patients and operators including the use of radiographic selection criteria for intraoral radiographic procedures. Results: The frequency of prescription of routine radiographic examination (an example is a panoramic radiograph for screening process for occult disease) was 34.1%, while that of selective radiography was 64.0%. Dentists' discussion of radiation risk and benefit with patients was infrequent. More than half of the operators held the image receptor by themselves during intraoral radiographic examinations. Lead apron/thyroid collars for patient protection were used by fewer than 22% of dental offices. Rectangular collimation was utilized by fewer than 15% of dental offices. Conclusion: The majority of Korean dentists in the study did not practice radiation protection procedures which would be required to minimize exposure to unnecessary radiation for patients and dental professionals. Mandatory continuing professional education in radiation safety and development of Korean radiographic selection criteria is recommended.

Comparison of Heavy Metal Pollutant Exposure and Risk Assessments in an Abandoned Mine Site (폐광산 주변 토양 중금속 오염노출농도 우려기준과 위해성 비교 연구)

  • Choi, Jinwon;Yoo, Keunje;Koo, Myungseo;Park, Joon-Hong
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.32 no.4B
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    • pp.261-266
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    • 2012
  • In this study, soil environmental impact assessment using risk-based approach was compared with that using concentration-based approach. For this, heavy metal contaminant exposure was characterized in an abandoned mine area. According to the estimated carcinogenic and non-carcinogenic risks, soil ingestion was identified as the most dominant exposure pathway. When contaminant concentrations exceeded the Korean Soil Contamination Warning Standards, their corresponding risk values also exceeded the Total Soil Risk Standard. Even the cases of satisfying the Korean Soil Contamination Warning Standards mostly showed higher risk levels than the Total Soil Risk Standard, re-confirming a more sensitivity of the risk-based assessment than concentration-based assessment. However, the in-depth analysis of the estimated non-carcinogenic risk values revealed a few cases for soil contact pathway showing contaminant concentrations higher than the Korean Soil Contamination Warning Standards although their non-carcinogenic risk values satisfied the level of Hazard Index Standard. The findings from this study support a necessity of shifting policy paradigm from concentration-based approach into risk-based approach for reliable risk assessment in abandoned mine areas, and also suggest a necessity of further fundamental studies regarding risk factors and standards.

Survival Rate and Prognostic Factors of Esophageal Cancer in East Azerbaijan Province, North-west of Iran

  • Mirinezhad, Seyed Kazem;Somi, Mohammad Hossein;Jangjoo, Amir Ghasemi;Seyednezhad, Farshad;Dastgiri, Saeed;Mohammadzadeh, Mohammad;Naseri, Ali Reza;Nasiri, Behnam
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3451-3454
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    • 2012
  • Background: Esophageal cancer in Iran is the sixth most common cancer and is particularly important in east Azerbaijan. The aim of this study was to calculate survival rates and define prognostic factors in esophageal cancer patients. Methods: In this study, all patients with esophageal cancer registered in the Radiation Therapy Center, during March 2006 to March 2011, were analyzed and followed up for vital status. Data were analyzed using the Kaplan-Meier method and the Cox proportional hazard models. Results: Out of 532 patients, survival information was available for 460, including 205 (44/ 5%) females and 255 (55/4%) males. The mean age was $65.8{\pm}12.2$, ranging from 29 to 90 years at the time of diagnosis. 1-, 3- and 5-year survival rates after diagnosis were 55%, 18% and 12%, respectively, with a median survival time of $13.2{\pm}.7$ (CI 95% =11.8-14.6) months. In the univariate analysis, age (P=0/001), education (P=0/001), smoking status (P= 0/001), surgery (P= 0/001), tumor differentiation (P= 0/003) and tumor stage (P= 0/001) were significant prognostic factors. Tumor morphology, sex, place of residence, tumor histology and tumor location did not show any significant effects on the survival rate. In multivariate analysis, age (P = 0/003), smoking (P= 0/01) and tumor stage (P= 0/001) were significant independent predictors of survival. Conclusion: In summary, prognosis of esophageal cancer in North West of Iran is poor. Therefore, reduction in exposure to risk factors and early detection should be emphasized to improve survival.

A Study on Exposure of Respiratory Hazard Factors in Food Service Workplace (국내 요식업 작업환경의 호흡기 유해인자 노출 연구)

  • Cha, Won-Seok;Kim, Eun-Young
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.30 no.1
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    • pp.75-86
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    • 2020
  • Objectives: In this study, we assessed respiratory hazards in the working environment as the work-relatedness of occupational diseases were examined. Methods: The subjects of the study were three Korean meat roasting restaurants, one Chinese restaurant, and two cafeterias. Measurement items were total dust, respirable dust, fine dust (PM2.5), PAHs, TVOCs, temperature, humidity, carbon monoxide, carbon dioxide, and nitrogen dioxide. Results: The concentration of total dust and respiratory dust in the restaurant was low. Most PAHs were undetectable, but some Napthalene and Acenaphthylene was detected. Thirteen kinds of PAHs were detected in one sample of roasted meat, and Benzo(a)pyrene was 1.496 ㎍/㎥. PM2.5, TVOCs, CO, and CO2 were instantaneously high, but the average concentration was low. NO2 was not detected. Conclusions: The results show that harmful substances such as PM2.5, PAHs, CO, and TVOCs were generated in the air in the catering industry. When roasting meat, Benzo(a)pyrene, a carcinogen related to lung cancer, was generated among PAHs. Lung cancer can occur when working for a long time in such a working environment. Therefore, it is necessary to improve the working environment for the health of restaurant workers, and it is necessary to evaluate the concentration of harmful substances by cooking method through further research.

Application of Mathematical Modeling to Extraplate from High Dose to Low Dose for Risk Assessment of Vinyl Chloride (화학물질의 건강 위해성 평가를 위한 수학 통계적 추계 모델링의 응용)

  • 이영조;이석호;이승진;정진호
    • Journal of Food Hygiene and Safety
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    • v.15 no.3
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    • pp.267-270
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    • 2000
  • This study was designed to predict the risk of a hazard chemical, vinyl chloride, by applying dose-response assessment that are one of the major process in practicing risk assessment. After extrapolating from the high dose exposure of vinyl chloride based upon animal carcinogenic data to the low dose exposed to human using several mathematical models, we calculated the cancer potency factors as well as virtually safe dose and the resulted values were compared. This process will provide the new insight to assess the risk of a chemical accurately imposed to human in the future.

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Comprehensive Assessment on Risk Factors using Fuzzy Inference in Decommissioning Process (퍼지추론을 이용한 해체공정 중 리스크 요인의 통합 평가)

  • Lim, Hyeon Kyo;Kim, Hyunjung
    • Journal of the Korean Society of Safety
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    • v.29 no.4
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    • pp.184-190
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    • 2014
  • Decommissioning process of nuclear facilities consist of a sequence of problem solving activities, because there may exist not only working environments contaminated by radiological exposure but also industrial hazards such as fire, explosions, toxic materials, and electrical and physical hazards. Therefore, not a few countries in the world have been trying to develop appropriate counter techniques in order to guarantee safety and efficiency of the process. In spite of that, there still exists neither domestic nor international standard. Unfortunately, however, there are few workers who experienced decommissioning operations a lot in the past. As a solution, it is quite necessary to utilize experts' opinions for risk assessment in decommissioning process. As for an individual hazard factor, risk assessment techniques are getting known to industrial workers with advance of safety technology, but the way how to integrate those results is not yet. This paper aimed to find out an appropriate technique to integrate individual risk assessment results from the viewpoint of experts. Thus, on one hand the whole risk assessment activity for decommissioning operations was modeled as a sequence of individual risk assessment steps which can be classified into two activities, decontamination and dismantling, and on the other, a risk assessment structure was introduced. The whole model was inferred with Fuzzy theory and techniques, and a numerical example was appended for comprehension.

Analysis and radiation dose assessment of 222Rn in indoor air at schools: Case study at Ulju County, Korea

  • Lee, ChoongWie;Choi, Sungyeol;Kim, Hee Reyoung
    • Nuclear Engineering and Technology
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    • v.50 no.5
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    • pp.806-813
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    • 2018
  • $^{222}Rn$ exists in nature in the form of a rare radioactive gas. In terms of environmental radiation, issues regarding $^{222}Rn$ have persisted because of its radiological hazardousness. Ulju County is one of the regions of Ulsan metropolitan city, with a population of 227,699. Ulju County has the highest density of industrial complexes in Korea. In this study, $^{222}Rn$ radioactivity concentration was measured and analyzed in 57 schools in Ulju County using 114 passive LR-115 type detectors to secure radiological safety and confirm basic information for reduction of resident exposure to $^{222}Rn$. The effective dose of $^{222}Rn$ was assessed to find the actual risk of the concentration surveyed in schools to human beings. The dose depended on four factors: subjects, $^{222}Rn$ concentration, dose coefficient, and time. The individuals subjected to dose estimation were classified into three types: students, teachers, and office workers. The subjects had different dwelling locations and times. The findings demonstrate that the radiological hazard to students and workers at schools in Ulju County owing to $^{222}Rn$ is negligible in terms of $^{222}Rn$ activity recommendation level.

Assessment factors for the Selection of Priority Soil Contaminants based on the Comparative Analysis of Chemical Ranking and Scoring Systems (국내.외 Chemical Ranking and Scoring 체계 비교분석을 통한 우선순위 토양오염물질 선정을 위한 평가인자 도출)

  • An, Youn-Joo;Jeong, Seung-Woo;Kim, Tae-Seung;Lee, Woo-Mi;Nam, Sun-Hwa;Baek, Yong-Wook
    • Journal of Soil and Groundwater Environment
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    • v.13 no.6
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    • pp.62-71
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    • 2008
  • Soil quality standards (SQS) are necessary to protect the human health and soil biota from the exposure to soil pollutants. The current SQS in Korea contain only sixteen substances, and it is scheduled to expand the number of substances. Chemical ranking and scoring (CRS) system is very effective to screen the priority chemicals for the future SQS in terms of their toxicity and exposure potential. In this study, several CRS systems were extensively compared to propose the assessment factors that required for the screening of soil pollutants The CRS systems considered in this study include the CHEMS-1 (Chemical Hazard Evaluation for Management Strategies), SCRAM (Scoring and Ranking Assessment Model), EURAM (European Union Risk Ranking Method), ARET (Accelerated Reduction/Elimination of Toxics), CRSKorea, and other systems. The additional assessment factors of CRS suitable for soil pollutants were suggested. We suggest soil adsorption factor as an appropriate factor of CRS system to consider chemical transport from soil to groundwater. Other factors such as soil emission rate and cases of accident of soil pollutants were included. These results were reflected to screen the priority chemicals in Korea, as a part of the project entitled ‘Setting the Priority of Soil Contaminants'.