• Clinical and Experimental Reproductive Medicine
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• v.25 no.2
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• pp.135-140
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• 1998

It was reported that the etiologies of recurrent spontaneous abortion are immunologic factors, endocrinologic problems, anatomical abnormalities, genetic abnormalities, infection, and unexplained factors. Among those etiologic factors, genetic abnormalities occur in about 5% of the couples who experience recurrent spontaneous abortions, and most common parental chromosomal abnormality contributing to recurrent abortion is balanced translocation. The advent of in vitro fertilization (IVF), the development of skills associated with the handling of human embryo, and an explosion of knowledge in molecular biology have opened the possibility of early diagnosis of genetic disease in preimplantation embryos. Therefore preimplantation genetic diagnosis (PGD) is indicated for couples, infertile or not, at risk of transmitting a genetic disease. A case of successful pregnancy and term delivery by PGD using fluorescence in situ hybridization (FISH) technique in patient with recurrent spontaneous abortion due to balanced translocation is presented with brief review of literatures.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.30 no.5
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• pp.427-434
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• 2017

Recently, awareness of the public about the explosion damage has increased due to the increased risk of terrorism. The criteria for blast-resistance design is not sufficient in Korea, it is necessary to develop blast-resistance design for the stability and safety of building by static analysis of current blast-resistance design. In addition, as the increase of earthquake occurrence necessitates the seismic design, it is studied to judge the blast-resistance performance of members applying seismic design without blast-resistance design. Currently, the general analysis of blast load is to refer to UFC 3-340-02 manual. Blast-resistance performance was studied by applying characteristics of blast load through UFC 3-340-02 manual, beam converted into equivalent SDOF System. It is proved that blast-resistance performance is improved when seismic detail is applied considering the maximum deflection of normal, intermediate, and special moment frames.

• Journal of the Ergonomics Society of Korea
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• v.35 no.2
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• pp.97-109
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• 2016

Objective: The aim of this study is to identify the domestic and foreign laboratory safety management system and to suggest domestic laboratory safety management policy priority. Background: Various types of accidents are occurred in research laboratories according to a variety of laboratory safety risks. However, there are only lists of incidents without any precise accident analysis. Method: We analyzed statistically the survey on current status of laboratory safety management of universities, research institutes, and industrial research institutions carried out by Ministry of Science, ICT and Future Planning in Korea. We also investigated laboratory safety management systems and safety organization carried out mainly in overseas countries such as USA, Japan, Switzerland and France. In addition, we analyze the UCLA College laboratory explosion occurred in the US in 2010. Results: More than 75 percent of 2015 domestic laboratory accidents were occurred in the field of operation management and chemistry research. Also, approximately 55% of accidents took place due to careless use mechanical instruments & dangerous chemicals. In addition, common difficulties of lab safety act applicable organizations are overlapping and comprehensive application of legal requirements. Conclusion: There is a need for laboratory safety professional organizations. Also, the high frequency of use of hazardous substances in the high-risk, such as the chemical field must be strengthened the laboratory safety management. In addition, it is needed to minimize the problems of the research organizations through close cooperation between related ministries and government support policy such as professional development program. Application: The result of this analysis might help to present a differentiated safety management policy and advanced safety management system in laboratory.

• Journal of the Korean Institute of Gas
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• v.8 no.4 s.25
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• pp.55-61
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• 2004

This paper provided a counter measures against the troubles and accidents that are likely to take place in the power plant using hydrogen gas as a coolant for the cooling system of the generator. Because of the extremely wide flammability limits of hydrogen in comparison to the other flammable gases, the safety measures against the hydrogen accidents is very important to ensure the normal operation of electric-power facility. This study's purpose was a presentation of standard model of safety management of hydrogen equipments in the coal firing power plant such as following items: 1) providing the technical prevention manual of the hydrogen explosions and hydrogen fires occurring in the cooling system of power generator; 2) the selection of explosion-proof equipments in terms of the risk level of operating environment; 3) the establishment of regulations and counter measures, such as the incorporation of gas leakage alarm device, for preventing the accidents from arising, 4) the establishment of safety management system to ensure the normal operation of the power plant.

• Journal of the Korean Institute of Gas
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• v.19 no.5
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• pp.98-103
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• 2015

Liquefied petroleum gas can be charged up to 85% of cylinder volume by enforcement regulations of safety control and business of liquefied petroleum gas act. The charged mass by enforcement regulations is considered by liquid expansion of internal liquefied petroleum gas at $65^{\circ}C$. But the temperature of liquid would not be suspended under $65^{\circ}C$ in a cylinder or portable vessel at certain situation. In the thermodynamics view point, the cylinder can be exposed to high pressure by liquid expansion. Consequently, it can be possible to potential risk such as physical explosion. Hence, this paper will offer a method of estimated internal pressure by liquid expansion at critical state in the closed system. Also, the structural factor which is given rise to volume increasement of cylinder is offered by experiment. This paper is expected as crucial reference for a cylinder design of liquefied petroleum gas.

• Journal of Energy Engineering
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• v.22 no.3
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• pp.294-301
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• 2013

The accidents related to boilers are caused by defects with high risk which can lead to the explosion of the equipment. The number of boiler accidents from 1979 to 2006 is 100 andthe casualties totaled 379, and the scale of accidents has been growing larger every year. The analysis has found that the number of accidents caused by carelessness in management is 59, 72% of total 82 cases and 18by low level of water. The analysis of accidents in foreign countries showed a similar result. From the past till today most of the accidents have been resulted from bad handlingand maintenance. The analysis of accidents for the inspected boilers also showed that the major cause of the accidents was bad handling and maintenance of automatic controllers, safety devices, etc. And in the large-scale explosive accidents, the number one cause of them was the low level of water.

• Journal of the Korean Institute of Gas
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• v.14 no.4
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• pp.6-11
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• 2010

The continuous fatal accidents like explosion or fire cause huge losses of both life and property in laboratories even though safety management system has been built and periodical checkups and safety diagnosis have been implementing in universities and enterprise-affiliated research institutes since Act on the Establishment of Safe Laboratory Environment was enacted in 2005 to prevent accidents in research laboratories. Cause analysis and safety management measures to prevent recurrence of accidents are urgently needed because accidents in research laboratories occur repeatedly with similar contents. This study will show results of analysis on incidents and accidents occurred in laboratories in universities and enterprise-affiliated research institutes using Root Cause Analysis Method and propose classified map of cause investigation and improvements so as to improve safety management in research laboratories.

• Journal of the Korean Institute of Gas
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• v.14 no.4
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• pp.1-5
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• 2010

Many sorts of fatal accidents like explosion or fire caused by gas leakage have become a social issue with the increasing use of harmful chemicals in laboratories in universities and enterprise-affiliated research institutes in Korea. Importance of safety management has been emphasized and it made Act on the Establishment of Safe Laboratory Environment enacted not only to protect lives and bodies of people working in laboratories in universities and enterprise-affiliated research institutes but also to make pleasant experimental atmosphere. Safety management system has been built and periodical checkups and safety diagnosis have been implementing in universities and enterprise-affiliated research institutes to prevent such accidents. However, in spite of those actions, continuous accidents make analysis of root cause essential. This study will show results of analysis on incidents and accidents occurred in laboratories in universities and enterprise-affiliated research institutes using Root Cause Analysis Method and propose the direction of safety management.

• Fire Science and Engineering
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• v.31 no.5
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• pp.70-77
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• 2017

As the quality of live gets better, the frequency of using air conditioner is along drastically increasing. On that matter, setting up measures of preventing increasing fire cases has been required. 43,413 fire cases occurred in last 2016, the cases occurred by electricity account for about 20%(8,655 cases). Among the electricity cases, the amount of cases occurred with air conditioner issues covers 1.5%; causes of the fire incidents vary, including incomplete contacts, short circuits, tracking, and such. In this study, we intend to investigate the case of ignition at the connection point where the power cord connected to the outdoor unit is arbitrarily connected during the air conditioner installation process, and to propose preventive measures against the cause in order to reduce the damage of life as well as the property from electric fire incidents.

• Journal of the Korean Institute of Gas
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• v.23 no.3
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• pp.40-45
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• 2019

Flash point is the important flammability indicator characterizing the risk of fire and explosion of flammable liquid mixture. In this study, flash points of water+formic acid and water+acrylic acid were measured by Seta flash apparatus. The flash points estimated by the methods based on empirical equation and Raoult's law were compared with experimental flash points. Absolute average errors of the results estimated by Raoult's law are $10.7^{\circ}C$ and $4.8^{\circ}C$ for water+formic acid and water+acrylic acid, respectively. Absolute average errors of the results estimated by empirical equation are $1.0^{\circ}C$ and $0.5^{\circ}C$ for water+formic acid and water+acrylic acid, respectively. In conclusion, the estimated values by empirical equation simulated the measured values better than those calculated by Raoult's law.