• 제목/요약/키워드: Experimental presentation

검색결과 275건 처리시간 0.031초

청색증형 선천성 심질환에 동반된 갈색세포종 (Pheochromocytoma associated with cyanotic congenital heart disease)

  • 정승준;이영아;신충호;양세원;배은정;노정일
    • Clinical and Experimental Pediatrics
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    • 제51권1호
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    • pp.93-97
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    • 2008
  • 갈색세포종은 부신 수질과 크롬친화성 조직에서 발생하는 소아기에는 드문 종양이다. 갈색세포종은 저산소증 상태와 연관이 있어, 단심실성 심장질환 수술 후에도 청색증이 지속되는 환자에서 병발하는 경우가 드물게 보고되고 있다. 갈색세포종의 증상이 애매할 뿐만 아니라 심장 질환 또는 치료 약제에 의하여 전형적인 증상들이 나타나지 않을 수 있다. 청색증형 선천성 심질환 환자에서 갑작스런 고혈압, 심장 상태의 악화, 또는 당뇨병 등을 포함한 애매한 증상들이 나타나는 경우에는 갈색세포종을 감별 진단하여야 한다. 저자들은 선천성 단심실성 심장질환과 갈색세포종이 동반된 2례를 보고한다.

갑상선호르몬 수용체 베타 유전자 돌연변이(H435Y)가 확인된 갑상선호르몬 저항성 증후군 1례 (Identification of a de novo mutation (H435Y) in the THRB gene in a Korean patient with resistance to thyroid hormone)

  • 신진영;기창석;김진경
    • Clinical and Experimental Pediatrics
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    • 제50권6호
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    • pp.576-579
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    • 2007
  • 갑상선 호르몬 저항성 증후군은 갑상선 호르몬에 대한 조직의 반응이 감소되어 나타나는 드문 유전 질환이다. 대부분은 갑상선 호르몬 수용체 (TR) 유전자의 돌연변이로 인한 갑상선 호르몬 수용체의 결함에 의한다. TR 유전자의 변이는 일반적으로 이형접합성이며 상염색체 우성 유전 양상을 보인다. 혈청 갑상선 호르몬 수치가 증가되어 있음에도 불구하고 혈청 갑상선 자극호르몬 수치가 억제되지 않으며, 임상 양상은 다양하다. 본 증례는 경미한 갑상선종, 총 및 유리 $T_4$, $T_3$의 증가, 정상 범위의 TSH 소견을 보이는 4세 여아로서 TR 유전자 분석에서 과오돌연변이(H435Y)를 확인하였다. 부모에서는 돌연변이가 관찰되지 않았으며, 갑상선 기능도 정상이었다. 특별한 투약 없이 추적 관찰 중에 갑상선종의 증가나 다른 증상의 악화는 없는 상태이다.

유피낭종으로 오인된 atretic encephalocele 2례 (Two cases of congenital atretic encephalocele misdiagnosed as dermoid cyst)

  • 김재희;조재민;정진명;박은실;서지현;임재영;박찬후;우향옥;윤희상
    • Clinical and Experimental Pediatrics
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    • 제49권9호
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    • pp.1000-1004
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    • 2006
  • Atretic encephalocele은 1972년 James와 Lassmann에 의해 meningocele manque로 처음 보고 되었고 뇌류의 퇴행성 형태로 정의하였다. 이후로 atretic, occult, abortive, rudimentary cephalocele 등의 다양한 명칭으로 명명되었으며 포함된 조직, 동반 기형, 발생 위치, 배아성 직정맥동의 유무 등에 따른 차이점들에 대해 다양하게 보고 되어왔다. 두정엽의 후부에 낭성 종물을 주소로 입원한 환아의 진단 과정에서 두부 초음파, CT, MRI를 시행하였으며 그 과정에서 MRI가 진단에 가장 효과적인 영상을 제공하였다. 환아 진단 후 수술적 방법으로 종물을 제거하였으며 수술 중 이상 소견 및 추후 관찰 기간 동안 이상 소견관찰되지 않았다. Atretic encephalcele의 희귀함과 진단 방법의 장단점 및 위치상 특성과는 다르게 동반 기형 및 발달 장애가 관찰되지 않은 증례를 치험 하였기에 보고하는 바이다.

Clinical outcome of acute myocarditis in children according to treatment modalities

  • Kim, Hyun-Jung;Yoo, Gyeong-Hee;Kil, Hong-Ryang
    • Clinical and Experimental Pediatrics
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    • 제53권7호
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    • pp.745-752
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    • 2010
  • Purpose: There is currently little evidence to support intravenous immune globulin (IVIG) therapy for pediatric myocarditis. The purpose of our retrospective study was to assess the effects of IVIG therapy in patients with presumed myocarditis on survival and recovery of ventricular function and to determine the factors associated with its poor outcome. Methods: We reviewed all consecutive cases of patients with myocarditis with left ventricular dysfunction verified by echocardiogram who had visited 3 university hospitals between January 2000 and September 2009. These patients were divided into 2 groups. Group 1 consisted of 23 patients (69.6%) who received IVIG alone or IVIG in combination with steroids, and group 2 consisted of 10 patients (30.3%) who received neither IVIG nor other immunosuppressive agents. Clinical manifestations, laboratory results, echocardiographic findings, and outcomes were compared between these 2 groups. Results: One year after the initial presentation, the difference in the probability of survival did not show statistical significance in IVIGtreated patients ($P$=0.607). Of the echocardiographic parameters on admission, a shortening fraction of less than 15% was associated with unremitting cardiac failure. Furthermore, anemic patients were more likely to have elevated N-terminal fragment levels of the B-type natriuretic peptide (NT-proBNP) in the progressed group ($P$=0.036). Conclusion: There was no difference between the IVIG-treated patients and the control patients in the degree of recovery of left ventricular function and survival. Prospective, randomized, clinical studies are needed to elucidate the effects of IVIG treatment during the acute stage of myocarditis on ultimate outcomes.

원격과학수업의 활용도 및 문제점, 학습자 행동분석 (Analysis of Utilization and Problems, and Learner Behavior of Distance Science Learning)

  • 이용섭
    • 대한지구과학교육학회지
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    • 제13권2호
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    • pp.175-185
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    • 2020
  • 본 연구의 목적은 원격과학수업의 활용도 및 문제점과 학습자 행동분석을 알아보는데 있다. 본 연구는 3월부터 6월까지 16주간에 거쳐 강의가 이루어졌으며 수강학생들에게 강의평가 및 설문조사를 하였다. 연구 대상은 B 교육대학교의 '초등과학교재연구 1' 강좌를 수강하는 128명을 대상으로 2020년 3월부터 6월까지 비대면 강의를 통해 강의평가 및 면담을 통해 조사하는 것이다. 이에 대한 연구결과는 다음과 같다. 첫째, 학습자의 입장에서는 대학의 LMS시스템 활용이 좋았다. 둘째, 교수자의 과학 자료제시가 온라인 시스템에서 원활하게 운영되는데 효율적이지 않았다. 다양한 플랫폼의 장단점을 살펴보면 교육의 적합성에 따라 달라질 수 있지만 전문적인 강의 지원방식인 LMS 시스템을 보다 학습자의 요구에 맞추어 업그레이드 한다면 보다 높은 교수자와 학습자의 만족도가 높을 것이다.

Fabrication of a Cu2ZnSn(S,Se)4 thin film solar cell with 9.24% efficiency from a sputtered metallic precursor by using S and Se pellets

  • 강명길;홍창우;윤재호;곽지혜;안승규;문종하;김진혁
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2015년도 제49회 하계 정기학술대회 초록집
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    • pp.86.2-86.2
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    • 2015
  • Cu2ZnSn(S,Se)4 thin film solar cells have been fabricated using sputtered Cu/Sn/Zn metallic precursors on Mo coated sodalime glass substrate without using a toxic H2Se and H2S atmosphere. Cu/Sn/Zn metallic precursors with various thicknesses were prepared using DC magnetron sputtering process at room temperature. As-deposited metallic precursors were sulfo-selenized inside a graphite box containing S and Se pellets using rapid thermal processing furnace at various sulfur to selenium (S/Se) compositional ratio. Thin film solar cells were fabricated after sulfo-selenization process using a 65 nm CdS buffer, a 40 nm intrinsic ZnO, a 400 nm Al doped ZnO, and Al/Ni top metal contact. Effects of sulfur to selenium (S/Se) compositional ratio on the microstructure, crystallinity, electrical properties, and cell efficiencies have been studied using X-ray diffraction, Raman spectroscopy, field emission scanning electron microscope, I-V measurement system, solar simulator, quantum efficiency measurement system, and time resolved photoluminescence spectrometer. Our fabricated Cu2ZnSn(S,Se)4 thin film solar cell shows the best conversion efficiency of 9.24 % (Voc : 454.6 mV, Jsc : 32.14 mA/cm2, FF : 63.29 %, and active area : 0.433 cm2), which is the highest efficiency among Cu2ZnSn(S,Se)4 thin film solar cells prepared using sputter deposited metallic precursors and without using a toxic H2Se gas. Details about other experimental results will be discussed during the presentation.

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Nano Fabrication of Functional Materials by Pulsed Laser Ablation

  • 윤종원
    • 한국재료학회:학술대회논문집
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    • 한국재료학회 2009년도 추계학술발표대회
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    • pp.6.2-6.2
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    • 2009
  • Nanostructured materials arecurrently receiving much attention because of their unique structural andphysical properties. Research has been stimulated by the envisagedapplications for this new class of materials in electronics, optics, catalysisand magnetic storage since the properties derived from nanometer-scalematerials are not present in either isolated molecules or micrometer-scalesolids. This study presents the experimental results derived fromthe various functional materials processed in nano-scale using pulsed laserablation, since those materials exhibit new physical phenomena caused by thereduction dimensionality. This presentation consists of three mainparts to consider in pulsed laser ablation (PLA) technique; first nanocrystallinefilms, second, nanocolloidal particles in liquid, and third, nanocoating fororganic/inorganic hybridization. Firstly, nanocrystalline films weresynthesized by pulsed laser deposition at various Ar gas pressures withoutsubstrate heating and/or post annealing treatments. From the controlof processng parameters, nanocystalline films of complex oxides and non-oxidematerials have been successfully fabricated. The excellentcapability of pulsed laser ablation for reactive deposition and its ability totransfer the original stoichiometry of the bulk target to the deposited filmsmakes it suitable for the fabrication of various functionalmaterials. Then, pulsed laser ablation in liquid has attracted muchattention as a new technique to prepare nanocolloidal particles. Inthis work, we represent a novel synthetic approach to directly producehighly-dispersed fluorescent colloidal nanoparticles using the PLA from ceramicbulk target in liquid phase without any surfactant. Furthermore, novel methodbased on simultaneous motion tracking of several individual nanoparticles isproposed for the convenient determination of nanoparticle sizedistributions. Finally, we report that the GaAs nanocrystals issynthesized successfully on the surface of PMMA (polymethylmethacrylate)microspheres by modified PLD technique using a particle fluidizationunit. The characteristics of the laser deposited GaAs nanocrytalswere then investigated. It should be noted that this is the first successfultrial to apply the PLD process nanocrystals on spherical polymermatrices. The present process is found to be a promising method fororganic/inorganic hybridization.

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Pub Med 검색을 통한 침구치료의 산과적 응용에 대한 최근 연구 고찰 (The Latest Trends of Acupuncture Therapy on Obstetrics)

  • 하지연;이진무;이창훈;장준복;이경섭;조정훈
    • 대한한방부인과학회지
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    • 제20권4호
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    • pp.132-147
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    • 2007
  • Purpose: We aimed at reviewing the studies of the acupuncture treatment for women related to pregnancy. Methods: We referred to PubMed by searching words of pregnancy and acupuncture and limited experimental method to randomized control trial. Results: We found 52 articles in 32 journals, which were divided into 3 parts: treatment for symptoms during pregnancy, treatment for symptom related to delivery and treatment for symptoms related to surgical operation for IVF-ET. In this study, articles on hypermesis gravidarum were the greatest in number and acupuncture for pain control related to pregnancy are most frequently appearing in terms of symptoms. Besides acupuncture treatment, acupressure band and acupressure were used for hyperemesis gravidarum, common acupuncture for low back pain in pregnancy and acupuncture or moxibustion to resolve breech presentation. Conclusion: In this study, acupuncture seems to be an efficacious means of reducing symptoms related to pregnancy and improving the quality of life of pregnant women.

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중학생들의 식품첨가물에 대한 인식과 교육에 관한 연구 (A Study on the Recognition and Education of Food Additives in Middle School Students)

  • 송효진;김성희;최선영
    • 한국식품영양학회지
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    • 제25권4호
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    • pp.957-967
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    • 2012
  • The purpose of this study is to offer youth with the basic materials for developing nutrition education programs and to help domestic science teachers in schools implement effective dietary education by examining their awareness of food additives. In the source of acquiring knowledges on food additives, the results were through mass media, technology and home economics teachers, and family members in order. The majority of students thought that they don't need the education about food additives. As effective teaching methods, they first selected the use of visual media, followed by experimental cooking classes, field trip, and inquiry lessons using processed foods. As a result of analyzing the education on food additives in accordance with demographic factors, more number of female students, compared to male students depicted the need for education on food additives. Further, the lower the cost students spend on purchasing processed foods per day, the higher the necessity of the education they indicate. The necessity of education content on food additives showed significant difference depending on the cost of buying processed foods, and the degree of interest and help real-life according to gender indicated significant differences. The satisfaction with education on food additives, which was implemented in home economics education revealed significant differences according to gender. This study aims to provide the basic data for the development and research of educational programs regarding good eating habits among the general youth. However, there are limitations to the presentation of the practical training program. For this reason, based on the results of this study, further studies should follow this study in order to develop and study educational programs related to food additives for teaching and learning purposes.

DEM을 이용한 수로망의 형태학적 표현 (Morphological Representation of Channel Network by Dint of DEM)

  • 김주철;김재한
    • 한국수자원학회논문집
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    • 제40권4호
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    • pp.287-297
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    • 2007
  • DEM을 이용하여 국부경사와 기여면적 사이의 규모에 따른 거동특성을 조사하여 면적한계기준과 경사-면적한계 기준이 상호보완적인 형태의 수로망 추적절차를 제시하였다. 상기방법과 현장자료에 대한 적용을 통하여 유역의 경사는 공간적으로 대규모의 산포경향을 갖는 지형인자임을 확인할 수 있었다. 양자의 규모에 따른 거동특성권역에 따라 지면의 형상은 발산지형과 수렴지형으로 분류될 수 있었다. 본 연구에서 제시한 수로망 동정 절차를 설마천 시험 유역에 대하여 수행한 결과 유역의 동적 거동을 확인할 수 있었다. 또한 이로부터 지형도를 이용한 수작업에 기초한 방법에 비하여 하천두부의 거동과 수로망의 동적특성을 잘 표현하고 있음을 볼 수 있었다.