• Title/Summary/Keyword: Experimental design and analysis

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Decomposition of Antibiotics (Cefaclor) by Ionizing Radiation: Optimization and Modeling Using a Design of Experiment (DOE) Based on Statistical Analysis

  • Yu, Seung-Ho;Chang, Soon-Woong;Lee, Si-Jin;Cho, Il-Hyoung
    • Environmental Engineering Research
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    • v.14 no.2
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    • pp.81-87
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    • 2009
  • The decomposition of antibiotics (cefaclor) by gamma irradiation in aqueous solutions was experimentally evaluated. To obtain a mutual interaction between two factors (antibiotics concentrations and radiation doses) and to optimize these factors during the process, experimental design and statistical analysis were employed. The decomposition capability of the gamma radiation was also mathematically described as a function of cefaclor concentration and gamma-ray dose using the statistical analysis. The results showed that the cefaclor concentration ($X_1$) in the response $Y_1$ (Reduction of cefaclor concentration) and gamma-ray dose ($X_2$) in the response $Y_2$ (Removal efficiency (%) of cefaclor concentration) exhibited a significantly positive effect, whereas gamma-ray dose ($X_2$) in the response $Y_1$ showed a significantly negative effect. The estimated ridge of maximum responses and optimal conditions for $Y_1$:($X_1$,$X_2$)=(25 mg/L, 350 Gy) and $Y_2$:($X_1$,$X_2$)=(21 mg/L, 565 Gy) using canonical analysis were 4.37 mg/L of reduction of cefaclor concentration and 98.35% of removal efficiency of cefaclor concentration, respectively. The measurement values agreed well with the predicted ones, thereby confirming the suitability of the model for $Y_1$ and $Y_2$ and the success of the experimental design in optimizing the conditions of the gamma irradiation process.

The Visual Information Processing and the Characteristics of Behaviour of the Architectural design Process Using Visual Protocol Analysis (시각적 프로토콜 분석법을 이용한 건축디자인의 시각정보처리 과정 및 행위 특성 분석)

  • 김용일
    • Korean Institute of Interior Design Journal
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    • no.19
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    • pp.53-58
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    • 1999
  • The goal of this paper is to understand the visual information process and the characteristics of behaviour of the architectural design process using visual protocol analysis through the actual experiment by the architect. The visual protocol analysis is developed on the basis of the theories of the visual information processing model and visual mental image, which can explain visual representation in architectural design process. A protocol study is reported in which the experimental data by architect is analyzed through the protocol analysis method. The whole design process is divided into the stage of 9 tasks which are classified into 18 visual representatiov. The results about visual cognition in cognitive science are reviewed and summarized, and these findings will help understand the architectural design nature.

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Multidisciplinary Design Optimization of Suspension System for Vibration Reduction of Drum Type Washer (진동저감을 위한 드럼세탁기 현가시스템의 다분야통합최적설계)

  • 이태희;현상학;유홍희;최동훈;전시문;김동원;김영호
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2004.05a
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    • pp.429-432
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    • 2004
  • Multidisciplinary design optimization technique is applied to drum type washer in order to minimize the vibration of the cabinet. Dynamic analysis and structural analysis are carried out by using commercial programs to obtain the reliable responses. Analysis models are compared to the experimental responses and finally validated for further design. Two commercial programs are integrated by the design framework EMDIOS that provides interfaces to conveniently link between analyzers and performs design optimization. In this research we could obtain an optimum design that reduces the magnitude of amplitude by about 33% compared with the original design.

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Experimental Analysis of Operating Parameters for Piezoelectric Jetting Dispenser (압전 젯팅 디스펜서의 작동 변수에 대한 실험적 분석)

  • Sohn, Jung Woo;Hong, Seung-Min;Kim, Gi-Woo;Choi, Seung-Bok
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.25 no.10
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    • pp.685-691
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    • 2015
  • In this work, to identify effective parameter for performance of piezoelectric jetting dispenser, experimental investigation is carried out based on design of experiment. After preparing jetting dispenser using two stack-type piezoelectric actuators, basic working principle of the jetting dispenser is described. Eight operating conditions are chose as main factors and it is assumed that each factor has two levels. To reduce number of experiments for performance evaluation, the experimental sets are designed based on factional factorial design method. Experimental setup is established and the weight of single dot is measured by using precision scale. The main and interaction effects of factors are analyzed using commercial statistical program and optimal operating condition for small amount and small variation of weight of dispensed single dot are determined.

Design of DC Motor by Using Experimental Data of Tested Motor (설계 파라메터 추출에 의한 직류 직권전동기의 설계)

  • Ha, Kyeong-Ho;Yeom, Sang-Bu;Hong, Jung-Pyo;Kim, Gyu-Tak;Jo, Jae-Ok
    • Proceedings of the KIEE Conference
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    • 2000.07b
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    • pp.738-740
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    • 2000
  • This paper presents the design process for series wound DC motor with the brush by using the experimental data of a tested motor. The design parameters calculated from the experimental data are friction loss. windage loss and contact resistance of brushes. The characteristic analysis of the designed motor is performed and then the proposed method is verified by comparing with experimental result.

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The Use of Advanced Optical Measurement Methods for the Mechanical Analysis of Shear Deficient Prestressed Concrete Members

  • Wilder, K. De;Roeck, G. De;Vandewalle, L.
    • International Journal of Concrete Structures and Materials
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    • v.10 no.2
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    • pp.189-203
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    • 2016
  • This paper investigates on the use of advanced optical measurement methods, i.e. 3D coordinate measurement machines (3D CMM) and stereo-vision digital image correlation (3D DIC), for the mechanical analysis of shear deficient prestressed concrete members. Firstly, the experimental program is elaborated. Secondly, the working principle, experimental setup and corresponding accuracy and precision of the considered optical measurement techniques are reported. A novel way to apply synthesised strain sensor patterns for DIC is introduced. Thirdly, the experimental results are reported and an analysis is made of the structural behaviour based on the gathered experimental data. Both techniques yielded useful and complete data in comparison to traditional mechanical measurement techniques and allowed for the assessment of the mechanical behaviour of the reported test specimens. The identified structural behaviour presented in this paper can be used to optimize design procedure for shear-critical structural concrete members.

Application of Analysis of Response Surface and Experimental Designs ; Optimization Methodology of Statistical Model (반응표면(反應表面) 분석(分析)을 위한 실험계획(實驗計劃)과 그 응용(鷹用) 통계적(統計的) 모형(模型)의 최적화수법론(最適化手法論)을 중심으로)

  • Lee, Myeong-Ju
    • Journal of Korean Society for Quality Management
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    • v.7 no.2
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    • pp.22-28
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    • 1979
  • The problem considered in this paper is to select the vital factor effect to the product quality through the experimental design and analysis of response surface, so as to control the quality improvement of industrial product. In this time, even through the mathematical model is unknown it could be applicable to control the quality of industrial products and to determine optimum operating condition for many technical fields, particulary, for industrial manufacturing process. When a set of data is available from an experimental design, it is often of interest 1:0 fit polynominal repression model in independent variables (eg, time, temperature, pressure, etc) the optimize the response variable (eg. yield, strength etc). This paper proposes a method known to obtain the optimum operating condition, and how to find the condition by using table of orthogonal array experiments, and optimization methodology of statistical model. A criterion can be applied determining to optimum operating conditions in manufacturing industry and improving the fit of response surface which may be used for prediction of responses and quality control of industrial products.

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Development of BioEquiv, a Computer Program for the Analysis of Bioequivalence (생물학적동등성시험을 위한 통계처리 프로그램(BioEquiv)의 개발)

  • Yoon, Sang-Hoo;Hwang, Nan-A;Lim, Young-Chai;Lee, Yong-Bok;Park, Jeong-Soo
    • Journal of Pharmaceutical Investigation
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    • v.40 no.1
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    • pp.1-7
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    • 2010
  • K-$BEtest^{(R)}$ is a well known program for bioequivalence test using a $2{\times}2$ design. Lee et al.(1998) and Park et al.(1999) suggested a $3{\times}3$ and $3{\times}2$ design, and also discussed their benefits. We developed a computer program, called BioEquiv, which can analyze some complex experimental designs such as, $3{\times}3$ design and $3{\times}2$ design including a standard $2{\times}2$ design. This program is a user-friendly one and overcomes the disadvantages of K-$BEtest^{(R)}$. The detailed statistical formula and structure of BioEquiv are presented with some examples. The comparison between K-$BEtest^{(R)}$ and BioEquiv are given with actual data analysis. BioEquiv is able to present a table of ANOVA test over some complex experimental designs. Moreover K-$BEtest^{(R)}$ and BioEquiv draw the same result when data consists of $2{\times}2$ design.

Effect of stiffened element and edge stiffener in strength and behaviour of cold formed steel built-up beams

  • Manikandan, P.;Sukumar, S.
    • Advances in Computational Design
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    • v.1 no.2
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    • pp.207-220
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    • 2016
  • The aim of this study is to investigate the effect of stiffened element and edge stiffener in the behaviour and flexural strength of built-up cold-formed steel beams. An experimental and analytical analysis of CFS channel sections in four different geometries is conducted, including simple channel sections, a stiffened channel section with or without edge stiffeners. Nonlinear finite element models are developed using finite element analysis software package ANSYS. The FEA results are verified with the experimental results. Further, the finite element model is used for parametric studies by varying the depth, thickness, and the effect of stiffened element, edge stiffener and their interaction with compression flanges on stiffened built-up cold-formed steel beams with upright edge stiffeners. In addition, the flexural strength predicted by the finite element analysis is compared with the design flexural strength calculated by using the North American Iron and Steel Institute Specifications for cold-formed steel structures (AISI: S100-2007) and suitable suggestion is made.

A Case study to Improve the Quality of Industrial Products cising An Experimental Design (공업제품(工業製品)의 질적(質的) 향상(向上)을 위(爲)한 실험계획(實驗計劃)의 응용사례(應用事例))

  • Kim, Yu-Song;Lee, Myeong-Ju
    • Journal of Korean Institute of Industrial Engineers
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    • v.7 no.2
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    • pp.55-59
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    • 1981
  • An Application of Experimental Designs to Improve the quality of Industrial product : optimization Methodology of statistical model. The primary object of this paper is to aid scientists and Engineers, in applying response surface procedures to obtain operating conditions for many technical fields, particularly for industrial manufacturing processes. The problem considered in this paper is to select technically and scientifically some important factors affecting the quality of products through the experimental design and analysis of response surface. Even though the mathematical model is unknown these statistical analysis can be applicable to control the quality of industrial products and to determine optimum operating conditions for many technical fields, particularly, for industrial manufacturing processes. This paper proposes a method to obtain the optimum operating condition, and how to find the condition by using table of orthogonal array experiments, and optimization methodology of statistical model.

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