Kim, Tae-Gyou;Park, Soon-Jee;Park, Jung-Whan;Suh, Chu-Yeon;Choi, Sin-Ae
Fashion & Textile Research Journal
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v.14
no.2
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pp.277-285
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2012
This research studied how to develop tight upper sportswear from 3D scan data considering fabric stretch property. Subjects were five Korean men of average figure in their 20's. Scanning was done for ten postures via vitus smart/pro(Techmath LTD). Analyzing from 3D scan data, more than 70% of the upper body surface showed surface change rate under 20%. It was shoulder and under arm side part that showed most noticeable body surface change when moving. A parametric model with convex surface was generated and flattened onto the plane, resulting 2D pattern. The error rate occurring in the process of 3D to 2D conversion was 0.2% for outline and 0.13% for area, respectively. Thirteen kinds of stretchable fabrics in the market were collected for this study. Stretch property was in the range of 16.0~58.2% for wale direction; 23.1~78.4% for course. Based on wear trial test, four fabrics were chosen for making the 1st experimental garment and finally one fabric was chosen for the 2nd one, which was developed applying 4 kinds of crosswise reduction rate on 2D pattern: 0, 5, 10, and 15%. Through wear trial test and garment pressure measurement, experimental garment applied with 10% pattern reduction rate was evaluated as most comfortable and considerable.
A dynamic model of lactic acid fermentation using Lactococcus lactis was constructed, and a metabolic flux analysis (MFA) and metabolic control analysis (MCA) were performed to reveal an intensive metabolic understanding of lactic acid bacteria (LAB). The parameter estimation was conducted with COPASI software to construct a more accurate metabolic model. The experimental data used in the parameter estimation were obtained from an LC-MS/MS analysis and time-course simulation study. The MFA results were a reasonable explanation of the experimental data. Through the parameter estimation, the metabolic system of lactic acid bacteria can be thoroughly understood through comparisons with the original parameters. The coefficients derived from the MCA indicated that the reaction rate of L-lactate dehydrogenase was activated by fructose 1,6-bisphosphate and pyruvate, and pyruvate appeared to be a stronger activator of L-lactate dehydrogenase than fructose 1,6-bisphosphate. Additionally, pyruvate acted as an inhibitor to pyruvate kinase and the phosphotransferase system. Glucose 6-phosphate and phosphoenolpyruvate showed activation effects on pyruvate kinase. Hexose transporter was the strongest effector on the flux through L-lactate dehydrogenase. The concentration control coefficient (CCC) showed similar results to the flux control coefficient (FCC).
Background: The purpose of present study was to investigate the effect of quadriceps femoris taping in normal gait using 3D motion capture technique. Method: Twenty healthy volunteers, have no musculoskeletal problems, were recruited as subjects for this study. In experimental group, 10 males (mean age : 23.6${\pm}$.40) and 10 females (mean age : 21.3${\pm}$.36) were included. Methods of therapeutic taping that taping of patellar inferior and medial gliding and quadriceps. To obtain the dynamic data, we captured the motion of subject attached markers without taping during repeated gaits five times or more in 7 m Capture volume of gait analysis center. The result was obtained as a mean value in three times. After taping on quadriceps femoris, the same procedure was carried out. Statistical analyses were performed using statistical software packagess SPSS WIN 12.0(SPSS, Chicago, IL, USA). Differences were tested for statistical significance using paired t-test, independent t-test, chi-squared test for comparisons between the male and female. Results: The date of 20 subjects who carried out the whole experimental course were statistically analyzed. 1. gait velocity was showed that female group had more significantly increased than male group(p<.05). 2. step length was showed that female group had more significantly increased than male group(p<.05). 3. step width was showed that female group had more significantly increased than male group(p<.05). Conclusion: Elastic taping on quadriceps femoris promoted cadence, gait velocity, step length and step width in normal subject group.
Lee, Joo Hwan;Lee, Jang Chul;Kim, Dong Won;Park, Ki Young;Lee, Sung Moon
Journal of Korean Neurosurgical Society
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v.29
no.1
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pp.101-107
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2000
Objectives : The evaluation of peripheral nerve injuries has traditionally relied on a clinical history, physical examination, and electrodiagnostic studies. The purpose of the present study was to examine serial magnetic resonance image(MRI) changes following acute muscle denervation under experimental conditions and to identify potential advantages and disadvantages of this use of MRI. Methods : An experimental transection of right sciatic nerve on Spargue-Dawley rats was performed. MRI was performed with T1-weighted spin-echo and STIR sequences. The imaging findings were compared with EMG in order to determine its sensitivity relative to this standard procedure. A simultaneous histopathological study provided information about the morphological basis of the imaging findings. Signal intensities were expressed as a ratio of abnormal to normal. Results : The signal intensity ratio of muscles with the STIR sequence was increased significantly at 2 weeks after sciatic nerve transection(p<0.05), although definite signal change was seen as early as 4 days postdenervation in one. EMG revealed significant denervation potential from 3 days after nerve transection. Diffuse cell atrophy was revealed hostologically at 2 weeks after transection, which was at the same time of significant signal change in MRI. Conclusion : MRI signal changes in denervated muscles secondary to nerve injury correlate with the degree of muscle atrophy on histologic examination. In addition to EMG, MRI can document the course of muscle atrophy and mesenchymal abnormalities in denervation. These results indicate that MRI can play a complementary role in the evaluation of patients with denervation.
This study aimed at evaluating the preventive effect of Glycyrrhizae Radix and Glycine Semen Extract (GGE) against NAC intoxication. NAC is widely used pesticide in many countries and derivative of carbamats and GGE is well-known antidote to some kinds of toxicants which was referenced from oriental medicine text. The results obtained were as follows: 1) After injecting NAC (100,140 mg/kg), determined Ch.E activities decrease 44.77~50.86% for all experimental groups at one hour after exposure, and were gradually recovered in the course of time. 2) In toxicity test of GGE, there were no sign of death or poisoning up to 5000 mg/kg of GGE for p.o. in mice. From this, we suggest that the LD$_{50}$ of GGE would be above 5000 mg/kg. 3) The Ch.E activity in control group was 471.43 $\pm$ 4.85 luff, group I was 215.27 $\pm$ 23.13 IU/l, group II and group III were 304.03 $\pm$ 9.03 IU/l, 433.81 $\pm$ 21.73 IU/l, respectively. Compare to the control group with experimental group I, remarkable difference revealed (p< 0.01), but the Ch.E activities of group II and III were similar to those of control group. This is indicate that GGE possess a potent activity of recovering Ch.E. GGE had a very remarkable preventive effect on NAC toxicity, and it was able to know that Ch.E activity dramatically increased according to GGE dosage increasing. 4) When GGE and NAC were administered by p.o. simultaneously, LD$_{50}$ and confidence intervals of each group were as follows: the control group: 270 mg/kg, 234.99~310.23 mg/kg, group I and II (GGE 500 mg/kg, 1000 mg/kg by p.o.): 310 mg/kg, 271.69~353.71mg/kg, and 325 mg/kg, 285.09~370.50 mg/kg, respectively. In the comparison with the control group, the protective index was 1.1 and 1.2, respectively. From the above result, GGE has reactivation effect to decreasing Ch.E activity induced by exposure to NAC. Furthermore, GGE shows a preventive effect on NAC intoxication.
Park, Jong-Wook;Jung, Hyun-Chul;Heo, Nam-Young;Shin, Myeong-kyeong
Journal of the Korean earth science society
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v.25
no.8
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pp.674-683
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2004
There is more than one way to conduct scientific research. In addressing the concern for educating the gifted in science towards achieving objectives of fostering their research skill, its elements need be explored and discussed by first admitting that various methodologies and features coexist in the name of scientific research. This study explores the various features of research skill presented as scientific process skills focusing on the students' experimental designing. Of course, there are several other domains included facets of research skill, such as problem finding, scientific knowledge, and self-efficacy. A Diet Cola Test (DCT) (Fowler. 1990) for digging into science process skills as an elements of research skills was administered to 705 students from 3rd to 10th grade, who enrolled the gifted education centers in Korea. Date was interpreted and analyzed based on the focus of Science education perspectives and research methods related to creative thinking and problem-based learning. But I eschew establishing and generalizing fixed constitutes of research skill from this research.
The purpose of this study was to identify the effect of imagery therapy on "coping mechanism and type C personality of the women with mastectomy. To achieve this purpose, 2 hours sessions of imagery therapy were given to the patients with breast cancer twice a week for 6 weeks. The period of data collection was from July, 7th to August, 12th 2002. The participants were 30 patients, 15 experimental group, 15 control group who were treated at the G University hospital in J City. This study was designed using a quasi-experimental approach with non-equivalent Pre test-Post test Design. The themes for the Imagery Therapy Program were composed of Leuner's(1969) 12 Imagery Themes: flower, green-field, stream, mountain, house, woods, significant figures, rose, lion, ideal self-image, cave and volcano. The data were analyzed with ${\chi}2-test$ and MANOVA using the SPSS program. The course of image change of the 12 imagery themes was analyzed by content analysis. The results of this study are as follows: First Hypothesis, 'The score of type C personality in the women with mastectomy who received imagery therapy will be significantly lower than that of the control group' was supported(p<.05). Second Hypothesis, 'The score of coping mechanism' in the women with mastectomy who received imagery therapy will be significantly higher than that of the control group' was rejected. In conclusion, imagery therapy is suggested as an effective nursing intervention to change type C personality of the women with mastectomy, but not effective to improve coping mechanism. Therefore, the program for the women with mastectomy should be developed to change their coping mechanism, method of problem solving and Quality of life.
The herb, Cajanus indicus L, is well known for its hepatoprotective action. A 43 kD protein has been isolated, purified and partially sequenced from the leaves of this herb. A number of in vivo and in vitro studies carried out in our laboratory suggest that this protein might be a major component responsible for the hepatoprotective action of the herb. Our successive studies have been designed to evaluate the potential efficacy of this protein in protecting the hepatic as well as renal tissues from the sodium fluoride (NaF) induced oxidative stress. The experimental groups of mice were exposed to NaF at a dose of 600 ppm through drinking water for one week. This exposure significantly altered the activities of the antioxidant enzymes like superoxide dismutase (SOD), catalase (CAT), glutathione-S-transferase (GST), glutathione reductase (GR) and the cellular metabolites such as reduced glutathione (GSH), oxidized glutathione (GSSG), total thiols, lipid peroxidation end products in liver and kidney compared to the normal mice. Intraperitoneal administration of the protein at a dose of 2 mg/kg body weight for seven days followed by NaF treatment (600 ppm for next seven days) normalized the activities of the hepato-renal antioxidant enzymes, the level of cellular metabolites and lipid peroxidation end products. Post treatment with the protein for four days showed that it could help recovering the damages after NaF administration. Time-course study suggests that the protein could stimulate the recovery of both the organs faster than natural process. Effects of a known antioxidant, vitamin E, and a non-relevant protein, bovine serum albumin (BSA) have been included in the study to validate the experimental data. Combining all, result suggests that NaF could induce severe oxidative stress both in the liver and kidney tissues in mice and the protein possessed the ability to attenuate that hepato-renal toxic effect of NaF probably via its antioxidant activity.
Journal of the Korean Society for Nondestructive Testing
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v.28
no.2
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pp.217-224
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2008
Trusses are found in many common structures such as bridges and buildings. The truss is a fundamental design element in engineering structures and it is important for an engineer to apply the truss design to engineering structures by understanding the mechanics of truss element. In an experimental course, the experiment selves as an example of the usefulness of the Wheatstone bridge in amplifying the output of a transducer. With the apparatus described here, it is possible to obtain experimental measurements of forces in a truss member which agree within errors to predictions from elementary mechanics. The apparatus is inexpensive, easy to operate, and suitable as either a classroom demonstration or student laboratory experiment. This device is a small table-top experiment. The conventional strain measuring device is costly and complicated - it is not simple to understand its structure. Hence, strain gage and the A/D converter are assembled to come up with a load and a strain measuring device. The device was tested for measuring the strain in a loaded specimen and the results were compared to those predicted by theory of mechanics.
Protein kinase C an enzyme of signal transduction has been known to regulate cell proliferation activation as well as apoptosis in some cancer cell lines. To explore the role of PKC in the course of cell mediated autoimmune disease such as experimental autoimmune encephalomyelitis (EAE) EAE was induced in Lewis rats(6-8 weeks old) with immunization of myelin basic protein supplemented with complete Freund's adjuvants and affected spinal cords were sampled at days 13 postimmunization(PI) as peak stage of EAE and at days 21 PI as recovery stage. The spinal cords with EAE were subjected to Northern blot analysis and insitu hybridization of PKC delta which is one of prominant isotypes of PKC in the haematopoietic cells. Northern blot analysis showed that levels of PKS delta mRNA in the spinal cords of rats withEAE was significantly increased at days 13 PI in which inflammatory cells including T cells and macrophages in the EAE lesions appeared. however the stage. By in situ hybridization signals of PKC delta in EAE lesions was intensely expressed on the delta is also expressed on some brain cells in normal rat central nervous system This finding suggests that PKC plays an important role on either activation of inflammatory cells including encephalitogenic T cells and macrophages or apoptotic elimination of some inflammatory cells depending on the stge of EAE.
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