The premise of this study is that an ultimate objective in planning an exhibition space is visitors' experiences created by a result of their first-hand experiences and responses within an exhibition space, and this result can be recognized in the visitors' movement. Thus, the exhibition layout that can directly affects viewers' main line of flow and movement patterns was examined vis--vis a mutually complementary relation in a triangular composition with the structure of exhibition space and the exhibition contents. This study, with the subjects of standing exhibit halls of Gwacheon National Science Museum, Daejeon National Science Museum, and Tokyo National Museum of Emerging Science and Innovation, analyzed 'the correlation between the configuration of the exhibition area and the visitors' movement. The targeted subjects were analyzed from the perspectives of type of architectural space and organization of the exhibition method, and the purpose of this study was to find a spatial evidence to predict the spectator movement formed within the exhibition halls of science museums. The main indicators used are: Based on the investigation/analysis as described above, the following conclusion could be drawn. Diversity of exhibition environment and spectator movement: besides the two big categories of the types of architectural space and types of exhibition method, the construction of vertical circulation and size and shape of the exhibition space, distribution characteristics of exhibition medium, organization of symbolic space and such other diverse organizations and combinations of exhibition environment are implied to have the capability to alter the scope and degree of predicting spectator movement. As an example, the types of architectural space comprising the wide-area viewing circulation was found to be able to change the system of planar circulation according to the composition of vertical circulation. Along with this, it was implied that the format of architectural space influences the form of the exhibition space, and may also act as a factor directly influencing the diversity and arrangement of the exhibition methods. That is, the spatial elements comprising the exhibition environment acts inter-complexly, and exhibits characteristics of limiting or controlling spectator movement.
Transactions of the Korean Society of Mechanical Engineers A
/
v.38
no.6
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pp.619-627
/
2014
An optimization method is proposed for the simultaneous design of structural and control systems using the equivalent static loads. In the past researches, the control parameters of such feedback gains are obtained to improve some performance in the steady-state. However, the actuators which have position and velocity feedback gains should be designed to exhibit a good performance in the time domain. In other words, the system analysis should be conducted for the transient-state in dynamic manner. In this research, a new equivalent static loads method is presented to treat the control variables as the design variables. The equivalent static loads (ESLs) set is defined as a static load set which generates the same displacement field as that from dynamic loads at a certain time. The calculated sets of ESLs are applied as multiple loading conditions in the optimization process. Several examples are solved to validate the proposed method.
Natural products are a rich source of biologically active small molecules and a fertile area for lead discovery of new drugs [10, 52]. For instance, 5% of the 1,031 new chemical entities approved as drugs by the US Food and Drug Administration (FDA) were natural products between 1981 and 2002, and another 23% were natural product-derived molecules [53]. These molecules have evolved through millions of years of natural selection to interact with biomolecules in the cells or organisms and offer unrivaled chemical and structural diversity [14, 37]. Nonetheless, a large percentage of nature remains unexplored, in particular, in the marine and microbial environments. Therefore, natural products are still major valuable sources of innovative therapeutic agents for human diseases. However, even when a natural product is found to exhibit biological activity, the cellular target and mode of action of the compound are mostly mysterious. This is also true of many natural products that are currently under clinical trials or have already been approved as clinical drugs [11]. The lack of information on a definitive cellular target for a biologically active natural product prevents the rational design and development of more potent therapeutics. Therefore, there is a great need for new techniques to expedite the rapid identification and validation of cellular targets for biologically active natural products. Chemical genomics is a new integrated research engine toward functional studies of genome and drug discovery [40, 69]. The identification and validation of cellular receptors of biologically active small molecules is one of the key goals of the discipline. This eventually facilitates subsequent rational drug design, and provides valuable information on the receptors in cellular processes. Indeed, several biologically crucial proteins have already been identified as targets for natural products using chemical genomics approach (Table 1). Herein, the representative case studies of chemical genomics using natural products derived from microbes, marine sources, and plants will be introduced.
Transactions of the Korean hydrogen and new energy society
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v.18
no.4
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pp.365-373
/
2007
We optimized the compositions of electrolyte and additives for anode in Ni-MH battery to improve the electrode characteristics at ambient and low temperatures using response surface method(RSM). Among various additives for anode, PTFE exhibited the greatest influence on the discharge capacity of the anode. Through response optimization process, we found the optimum composition of the additives to exhibit the greatest discharge capacity. When the amount of additives was too small, the anode was degraded with time due to the low binding strength among alloy powders and the resultant separation of powders from the current collector. In contrast, the addition of large amount of the additives increased in the resistance of the electrode. In addition, the discharge capacity of the anode at $-18^{\circ}C$ increased with decreasing the concentration of KOH, NaOH and LiOH in design range of electrolyte. The resistance and viscosity of electrolyte appear to affect the discharge capacity of the anode at low temperature.
By testing the separation performance for a fine settleable solid removal system in an aquaculture system using polystyrene particles as an experimental substitute, the optimal geometric dimensions for a Low-Pressure Hydrocyclone (LPH) were obtained. The design approach far the LPH took into consideration two inflow diameters (Di: 30, 50 mm), three overflow diameters (Do: 60, 70, 100 mm) and four cylinder lengths (Lc: 250, 345, 442, 575 mm), while the cylinder diameter (Dc) at 335 mm, the underflow diameter (Du) at 50 mm and the cone angle (${\theta}$) at $68^{\circ}$ were kept constant. The separation performances of 19 different dimension combinations of LPH were tested, ranging from 300 to 1200 ml/sec of inflow rate using substitute polystyrene particles (0.4-0.7 mm dia., ${\rho}_s=1.05g/cm^3$). These polystyrene particles exhibit a similar density and settling velocity to the fine fecal debris of the common carp. The total separation efficiency for the inflow rate ranged from a high of 97% to a low of 20%. Experimental results obtained by ANCOVA and the Tukey test (${\alpha}=0.05$) showed that the separation performances of the LPH were significantly affected (P<0.05) by the fi, Di, Do and Lc. The maximum separation performance was detected at a dimension combination of 30 mm of inflow diameter (Di), 60 mm of overflow diameter (Do), 442 and 575 mm of cylinder length (Lc). The dimension proportions were 0.09, 1.32-1.72, 0.18 and 0.15 for Di/Dc, Lc/Dc, Do/Dc and Du/Dc respectively.
This study researched the costume manufacture process by having the musical 'Christmas Carol' as an example and specifically presented the costume manufacture process of an actually performance work, thus it aimed to be helpful theoretically and realistically, by allowing theatrical costume manufacturers and majors in theatrical costume to be informed of the systematically practical affair process of the theatrical costume manufacture and by exhibiting the research work of costume composition aiming at reproducing a silhouette in the process such as costume composition and sewing, and the effectively manufacturing methods such as the costume composition application and the sewing method development aiming at the activity of performers. In the empirical research, it analyzed the features of characters and arranged the manufacture points while actually manufacturing the performance costume, and clarified the systematically performance costume manufacture process such as a manufacture meeting${\rightarrow}$costume list preparation$\rightarrow$work-instruction sheet preparation$\rightarrow$pattern manufacture$\rightarrow$sewing$\rightarrow$performance and inspection. Through performing the manufacture of the really performance work, it is hoped that this study contributes to the development of performance art circles, by presenting a step and a method of professionally theatrical costume to the performance manufacturers and the theatrical costume manufacturers at present when the theatrical costume is solidifying its position as a professional sphere, in the performance and an, has a meaning as the initially empirical research, which can exhibit as a guide of realistically and empirically educational contents for theatrical costume aiming to bring up professional staff for theatrical costume, and becomes help in the efficiently theatrical costume manufacture realistically.
The purpose of this study is to propose a solution for Goguryeo costume and its materials, colors, patterns, and accessories, which have not been dealt with in precedent studies and were treated as irrelevant subjects. The specific object of reconstruction with identification from the historical viewpoint is noble woman's costume(Yu and Gun) on the mural paintings of Jang-Cheon No.1 tomb in Jip-An province. As above, the reconstruction process of Yu(Jacket) and Gun(Skirt) worn by noble woman as depicted on the mural painting of the Baek-Hee-Gi-Ak-Do(百戱伎樂圖) in Jang-Cheon No.1 ancient tomb is suggested in this study. The most important issue for consideration was how to represent and exhibit it so that it resembles the mural painting as closely as possible. And the problems that arose at the time were the ratio and silhouette, which revealed disparities between the one on the mural painting and the costumes reproduced with identification from a historical viewpoint. The most difficult aspect of this work was due to the fact that the actual mural paintings were not available for verification. Therefore accuracy on details such as structure, materials, colors, patterns and accessory were difficult to obtain. So a further analysis of patterns, silhouettes, materials and colors are required for the precise representation of costume and dress on the mural painting.
In this paper, we proposed a new circuit construction method that reduces the number of circuit devices of fuzzy controller. Sasaki had defined a new operator to eliminate the divide circuit comparing with the center of gravity method which often using to design the fuzzy controller. In this paper we obtained the more compacted fuzzy controller's circuit by using the proposed definition of fuzzification and defuzzification than using the Sasaki's method and the fuzzification and defuzzification are reverse operation each other. Using these definitions we exhibit the new design method and circuit structure that can eliminate the bounded product(BP) circuit included in Sasaki's circuit. Using the proposed method to level controlling of the water tank, we verified the fuzzy controller's performance by using existent method and proposed method. As a result that are calculated by using the Proposed fuzzy controller to level controlling of the water tank, total numbers of blocks and devices were decreased. If the number of variables and antecedents are Be11ing larger, this method is more efficient.
Journal of the Korean Society of Clothing and Textiles
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v.42
no.1
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pp.88-103
/
2018
Message sidedness of fashion salespersons on consumer behavior with the consideration of the mediating roles of trust and cognitive efforts, and the moderation of a regulatory focus of consumers. Two scenarios were devised, a single message in which a salesperson explains only the advantages of a product to customers, and the second with a double message that explains both the advantages and drawbacks of the product. The results showed that participants trusted a fashion salesperson more and perceived stronger cognitive effort for two-sided messages. The two-sided messages mediated the consumer's trust in the salesperson and cognitive effort, and influenced consumers' buying behavior. This study also found that salesperson trust was stronger in the two-sided messages scenario than in the one-sided message scenario, regardless of consumers' focused preference, and that it was more effective for promotion focus customers. The analysis of the results on consumers' cognitive effort indicated that prevention focused customers did not exhibit any difference in cognitive effort concerning two-sided messages. However, promotion focused customers exhibited an increased cognitive effort in the two-sided message scenario than in the one-sided message scenario. Marketing implications were discussed based on the findings.
It generally accepted that most building structures shall exhibit a nonlinear response when subjected to medium-high intensity earthquakes. It is currently known, however, that this phenomenon is not properly modelled in the majority of cases, especially at the design stage, where only simple linear methods have effectively been used. Recently, as a result of the exponential progress of computational tools, nonlinear modelling and analysis have gradually been brought to a more promising level. A wide range of modelling alternatives developed over the years is hence at the designer's disposal for the seismic design and assessment of engineering structures. The objective of the study presented herein is to test some of these models in an existing structure, and observe their performance in nonlinear static and dynamic analyses. This evaluation is done by the use of two of a known range of advanced computer programs: SAP2000 and SeismoStruct. The different models will focus on the element flexural mechanism with both lumped and distributed plasticity element models. In order to appraise the reliability and feasibility of each alternative, the programs capabilities and the amount of labour and time required for modelling and performing the analyses are also discussed. The results obtained show the difficulties that may be met, not only in performing nonlinear analyses, but also on their dependency on both the chosen nonlinear structural models and the adopted computer programs. It is then suggested that these procedures should only be used by experienced designers, provided that they are aware of these difficulties and with a critical stance towards the result of the analyses.
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