• 제목/요약/키워드: Excess lifetime cancer risk

검색결과 22건 처리시간 0.023초

한국인의 초과 방사선 암 위험도 평가에 근거한 국내원전의 안전목표치 설정 방법론 (Methodology on the Safety Goal Setting of Reactor Operation based on the Radiogenic Excess Cancer Risk in Korea)

  • 장시영;정운관
    • Journal of Radiation Protection and Research
    • /
    • 제24권3호
    • /
    • pp.131-142
    • /
    • 1999
  • 통계청에서 최근에 발표한 한국인 인구통계 자료와 미국 학술원 산하 '방사선의 생물학적 영향 위원회'의 최근 보고서(BEIR-V)의 수정 상대위험 투사모델을 적용하여 한국인의 방사선 피폭에 의한 초과 암발생 위험도를 평가하였다. 인구통계 자료로부터 유도한 사소위험도(trivial risk) 및 계산된 방사선유발 초과 암 위험도를 비교한 후 사소위험도의 수준으로 개인의 피폭선량을 유지하기 위한 국내 원전의 안전운영 목표치를 유도하였다. 방사선 피폭 유발 초과 암 위험도는 0.1 Gy의 단일피폭의 경우에는 $5.5{\times}10^{-3}$, 1.0 mGy/y로 생애연속 피폭 시엔 $3.7{\times}10^{-3}$인 것으로 평가되었다. 한국인의 모든 원인에 의한 기저사망 위험도 및 사소위험도는 각각 $5.2{\times}10^{-3}$$5.2{\times}10^{-6}$인 것으로 예상되었다. 한국인의 사소위험도 및 방사선 위험도 평가 결과로부터 유도한 국내 원전운영의 안전목표치는 대략 0.05 mSv/y로, 이 값은 미국 원자력규제위원회(USNRC)가 연방규제법 10CFR50 부록 I에서 제시하고 있는 ALARA 지침값과 거의 동일한 값으로 밝혀졌다.

  • PDF

어린이 주요 활동 공간의 휘발성 유기화합물 노출로 인한 건강 위해성 평가 -보육시설 및 실내놀이터 중심으로- (Health Risk Assessment of Aldehydes and VOCs in the Activities Space of Young Children -Focused on Child-care Facilities and Indoor Playgrounds-)

  • 양지연;김호현;양수희;김선덕;전준민;신동천;임영욱
    • Environmental Analysis Health and Toxicology
    • /
    • 제25권1호
    • /
    • pp.57-68
    • /
    • 2010
  • This study assessed the lifetime cancer and non-cancer risk of aldehydes and volatile organic compounds exposure of young children at child-care facilities and indoor playgrounds in Korea. The samples were collected at various children's facilities (40 day-care houses, 42 child-care centers, 44 kindergartens, and 42 indoor playgrounds) in summer (Jul~Sep, 2007), winter (Jan~Feb, 2008) and Spring (Mar~Apr, 2008) periods, and analyzed by GC-MS. We estimated the lifetime excess cancer risks (ECRs) of formaldehyde, acetaldehyde, benzene, chloroform, CCI4 and tetrachloroethylene, and the hazard quotients (HQs) of Non-carcinogens (toluene, xylene, benzaldehyde and formaldehyde). Formaldehyde evaluated both cancer and non-cancer risk. The average ECRs of formaldehyde for young children were $1\times10^{-4}{\sim}1\times10^{-5}$ level in all facilities. HQs of four non-carcinogens did not exceed 1.0 for all subjects in all facilities.

우리나라 일부 석면광산 지역에서 ABS를 이용한 석면노출 및 위해성 평가 (Asbestos Exposure and Risk Assessment by ABS(Activity Based Sampling) for Former Asbestos Mining Areas in Korea)

  • 이준혁;김대종;최성원;김현욱
    • 한국산업보건학회지
    • /
    • 제25권1호
    • /
    • pp.72-81
    • /
    • 2015
  • Objectives: The aim of this study was to investigate the exposure and risk assessment of residents near asbestos mines in Korea. Methods: To assess asbestos types and airborne concentrations, air monitoring was performed in the neighborhoods of Kwangcheon (KC) and Sinsuk (SS) mines, which were leading South Korean mines in the past. In addition, activity-based-sampling (ABS) of residents' particular activities were conducted in order to estimate the Excess Lifetime Cancer Risks (ELCRs) for the residents. Conclusions: The average concentration of airborne asbestos in KC was 0.0014 f/cc and 0.0015 f/cc by PCM and TEM, respectively. In SS it was equal at 0.0012 f/cc by PCM and TEM. No statistically significant difference was found in the average concentration of airborne asbestos between the two mines. The average asbestos concentration of ABS was 0.0048 f/cc (PCM) and 0.0042 f/cc (TEM) in KC, while it was 0.0137 f/cc (PCM) and 0.0125 f/cc (TEM) in SS. It was found that the average asbestos concentration of ABS in SS was statistically significantly higher than that of KC (p<0.01). The results of ELCRs by scenario in KC showed that the scenarios of bicycle, car, weed control, weed whacking, child playing in the dirt, and physical training fell within $1{\times}0^{-6}-1{\times}10^{-4}$, which is the acceptable range of ELCR. The scenarios of motorcycle, walker, digging, and field sweeping, however, exceeded the acceptable range. In SS, only the scenario of car fell within the acceptable range, while all of the other scenarios exceeded the acceptable range.

일부 미적용 다중이용시설의 실내 공기 중 알데히드류 및 휘발성유기화합물 노출로 인한 건강위해성 평가 (Health Risk Assessment of Occupants in the Small-Scale Public Facilites for Aldehydes and VOCs)

  • 양지연;김호현;신동천;김윤신;손종렬;임준환;임영욱
    • 한국환경과학회지
    • /
    • 제17권1호
    • /
    • pp.45-56
    • /
    • 2008
  • This study was to assess the lifetime cancer and non-cancer risk of exposure of worker and user at public facilities in Korea to volatile organic compounds (VOCs). We measured the concentrations of two aldehydes and five VOCs in indoor air at 424 public buildings that 8 kinds of public facilities (70 movie theaters, 86 offices, 86 restaurants, 70 academies, 22 auditoriums, 30 PC-rooms, 30 singing-rooms and 30 bars) all over the country. There were estimated the human exposure dose and risks with averages of the using-time and frequency for facility users and office workers, respectively. Carcinogens (formaldehyde, acetaldehyde, and benzene) were estimated the lifetime excess cancer risks (ECRs). non-carcinogens (toluene, ethylbenzene, xylene, and styrene) were estimated the hazard quotients (HQs). The average ECRs of formaldehyde and benzene for facility worker and user were $1{\times}10^{-3}{\sim}1{\times}10^{-4}\;and\;1{\times}10^{-4}{\sim}1{\times}10^{-5}$ level, respectively, in all facilities. HQs of four non-carcinogens did not exceed 1.0 for all subjects in all facilities. The estimated ECRs for restaurant and auditorium were the highest, and the PC-room and bar were the next higher facilities. Furthermore, people in a smoking facility had the highest cancer risk. Higher ECRs of formaldehyde and benzene were observed in indoor smoking facilities such as restaurant and auditorium. Higher HQs of toluene and xylene were observed at the restaurant and office building.

Natural radioactivity level in fly ash samples and radiological hazard at the landfill area of the coal-fired power plant complex, Vietnam

  • Loan, Truong Thi Hong;Ba, Vu Ngoc;Thien, Bui Ngoc
    • Nuclear Engineering and Technology
    • /
    • 제54권4호
    • /
    • pp.1431-1438
    • /
    • 2022
  • In this study, natural radioactivity concentrations and dosimetric values of fly ash samples were evaluated for the landfill area of the coal-fired power plant (CFPP) complex at Binh Thuan, Vietnam. The average activity concentrations of 238U, 226Ra, 232Th and 40K were 93, 77, 92 and 938 Bq kg-1, respectively. The average results for radon dose, indoor external, internal, and total effective dose equivalent (TEDE) were 5.27, 1.22, 0.16, and 6.65 mSv y-1, respectively. The average emanation fraction for fly ash were 0.028. The excess lifetime cancer risks (ELCR) were recorded as 20.30×10-3, 4.26×10-3, 0.62×10-3, and 25.61×10-3 for radon, indoor, outdoor exposures, and total ELCR, respectively. The results indicated that the cover of shielding materials above the landfill area significantly decreased the gamma radiation from the ash and slag in the ascending order: Zeolite < PVC < Soil < Concrete. Total dose of all radionuclides in the landfill site reached its peak at 19.8 years. The obtained data are useful for evaluation of radiation safety when fly ash is used for building material as well as the radiation risk and the overload of the landfill area from operation of these plants for population and workers.

GIS 기법을 이용한 폐석면 광산의 위해성 평가 (Health Risk Assessments using GIS Method for the Abandoned Asbestos Mines)

  • 최진범;손일;노진환
    • 한국광물학회지
    • /
    • 제24권1호
    • /
    • pp.43-53
    • /
    • 2011
  • 폐석면 광산의 위해성 평가는 통상 ABS 방식에 의해 이루어지지만, 조사지역 전반에 관한 위해성 경향을 파악하는 데 그치는 한계를 지닌다. 이 연구에서는 새로운 평가방식으로 잠재적 위해지수(PIHR)라는 개념을 도입하여 석면 위해도를 계랑화하였다. PIHR 값에 대해 석면이 인체에 위해를 주는 요인들을 고려하여 적절한 가중치를 부여한 후, 토양 내 석면 농도 값을 적용하여 지리정보시스템(GIS)의 적지선정기법을 활용하여 위해성 평가를 실시하였다. 충청남도 보령시에 위치한 어느 폐석면 광산에 적용한 결과, 잠재적 위해 지수가 매우 높은 지역은 전체 면적의 7.8%에 해당되는 27.3 ha이며, 위해성 평가는 미국 환경보호청의 종합위해정보시스템(IRIS) 모델을 적용하여 각각 만 명당 1명(석면농도 0.36% 이상), 3만 명당 1명(석면농도 0.1% 이상), 10만 명당 1명(석면농도 0.04% 이상) 평생초과 발암 위험도 기준으로 관리할 경우 3.0, 12.9, 19.5 ha로 면적이 증가한다. 이러한 결과는 향후 광해 복원범위 선정에 효과적으로 적용할 수 있다.

납의 다경로 노출에 의한 건강위해성평가 : 우리 나라 일부 지역 성인들을 대상으로 (Health Risk Assessment of Lead Exposure through Multi-pathways in Korea)

  • 정용;황만식;양지연;조성준
    • Environmental Analysis Health and Toxicology
    • /
    • 제14권4호
    • /
    • pp.203-216
    • /
    • 1999
  • This paper describes a set of multi-pathway models for estimating health risk to lead. The models link concentrations of an environmental contaminant (lead) in air, water and food to human exposure through inhalation, ingestion, and dietary routes. Exposure is used as the foundation for predicting risk of health detriment within the population. The process of estimating exposure using often limited data and extrapolating to a large diverse population requires many assumption, inferences, and simplification. This paper is divided into four section. The first section provides lead contaminant levels on obtaining environmental concentration of air, tap water, and foods. The second section provides a discussion of exposure parameters and uncertainty associated predicting human health risk of contaminants. The third and fourth section illustrate lifetime average daily exposure (LADE) and excess cancer risk (ECR) based on exposure parameters. The relationship between concentration of lead in an environmental medium and human exposure is determined with pathway exposure factors (PEFs). The calculation of LADE and ECR is carried out using Monte-Carlo simulation with probability density function of exposure parameters. Examination of the result reveals that, for lead exposure, ingestion (food) is the dominant route of exposure rather than inhalation (air), and ingestion (tap eater).

  • PDF

Radionuclide concentrations in agricultural soil and lifetime cancer risk due to gamma radioactivity in district Swabi, KPK, Pakistan

  • Umair Azeem;Hannan Younis;Niamat ullah;Khurram Mehboob;Muhammad Ajaz;Mushtaq Ali;Abdullah Hidayat;Wazir Muhammad
    • Nuclear Engineering and Technology
    • /
    • 제56권1호
    • /
    • pp.207-215
    • /
    • 2024
  • This study focuses on measuring the levels of naturally occurring radioactivity in the soil of Swabi, Khyber Pakhtunkhwa, Pakistan, as well as the associated health hazard. Thirty (30) soil samples were collected from various locations and analyzed for 226Ra, 232Th, and 40K radioactivity levels using a High Purity Germanium detector (HPGe) gamma-ray spectrometer with a photo-peak efficiency of approximately 52.3%. The average values obtained for these radionuclides are 35.6 ± 5.7 Bqkg-1, 47 ± 12.5 Bqkg-1, and 877 ± 153 Bqkg-1, respectively. The level of 232Th is slightly higher and 40K is 2.2 times higher than the internationally recommended limit of 30 Bqkg-1 and 400 Bqkg-1, respectively. Various parameters were calculated based on the results obtained, including Radium Equivalent (Raeq), External Hazard (Hex), Absorbed Dose Rate (D), Annual Gonadal Equivalent Dose (AGDE), Annual Effective Dose Rate, and Excess Lifetime Cancer Risk (ELCR), which are 170.3 ± 24 Bqkg-1, 0.46 ± 0.06 Bqkg-1, 81.4 ± 2.04 nGy h-1, 582 ± 78.08 µSvy-1, 99.8 ± 13.5 µSv Gy-1, and 0.349 ± 0.04, respectively. These values are below the limits recommended by the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) in 2002. This study highlights the potential radiation threats associated with natural radioactivity levels in the soil of Swabi and provides valuable information for public health and safety.

Assessment of radioactivity levels and radiation hazards in building materials in Egypt

  • Ahmed E. Abdel Gawad;Mohamed Y. Hanfi;Mostafa N. Tawfik;Mohammed S. Alqahtani;Hamed I. Mira
    • Nuclear Engineering and Technology
    • /
    • 제56권2호
    • /
    • pp.707-714
    • /
    • 2024
  • Different degrees of natural radioactivity found in quartz can have negative consequences on health. Quartz vein along the investigated Abu Ramad area, Egypt, had its natural radioactivity assessed. The HPGe spectrometer was used to determine the role played by the radionuclides 238U, 232Th, and 40K in the gamma radiation that was emitted, and the results showed that these concentrations are 484.64 ± 288.4, 36.8 ± 13.1 and 772.2 ± 134.6 Bq kg-1 were higher than the corresponding reported global limits of 33, 45, and 412 Bq kg-1 for each radionuclide (238U, 232Th, and 40K). Among the radiological hazard parameters, the excess lifetime cancer risk (ELCR) is estimated and it's mean value of ELCR (1.2) is higher than the permissible limit of 0.00029. The relationship between the radionuclides and the associated radiological hazard characteristics was investigated based on multivariate statistical methods including Pearson correlation, principal component analysis (PCA), and hierarchical cluster analysis (HCA). According to statistical research, the radioactive risk of quartz is primarily caused by the 238U, 232Thand 40K. Finally, applying quartz to building materials would pose a significant risk to the public.

암의 조기발견을 위한 CT촬영에서의 임상적 효능과 방사선위해에 대한 고찰 (Review of the Radiation Risk and Clinical Efficacy Associated with Computed Tomography Cancer Screening)

  • 김현자
    • Journal of Radiation Protection and Research
    • /
    • 제38권4호
    • /
    • pp.214-227
    • /
    • 2013
  • MDCT의 등장과 함께 병적 증상이 없는 개인이 조기검진을 위해 CT검사를 하는 예가 꾸준히 증가하고 있다. 이러한 검사의 임상적 효용성과 방사선에 의한 암 발생위험에 대한 여러 가지 논란을 살펴보았다. 1. 저선량흉부CT(LDCT)를 이용한 폐암의 조기 검진 효용성을 보기 위해 설계된 무작위배정대조검사(randomized controlled trial)인 NLST(National Lung Screening Trial)의 분석 결과, CT선별검사가 선별검사를 하지 않은 그룹의 사망률 1.67%를 1.33%로, 20% (p=0.004) 감소시키는 것으로 나타났다. CT선별검사군에서 양성결과를 보인 사람의 96.4%는 위양성(false-positive)이었다. 그리고 방사선에 의한 폐암의 ERR (excess radiation risk)은 다른 고형암과는 달리 나이와 함께 감소하지 않으며, 더욱이 흡연 위험과 방사선 위험이 상승작용을 하여 폐암 검진 대상인 고위험군에게 더욱 위험할 수 있는 것으로 평가되었다. 따라서 방사선에 의한 위험이 NLST에서 관측한 이득을 상쇄할 수도 있다. 아직은 최적의 전략이 확립되지 않은 상태이므로 임상에서 광범위하게 적용하기에는 한계가 있다. 2. 대장CT검사(CT colonography)는 10 mm보다 큰 용종의 검출에는 정확도가 뛰어나지만 이보다 작은 경우에는 민감도와 특이도가 급격히 감소하고, 용종이 발견되어 제거하고자 하는 경우 다시 기존의 대장내시경을 이용해야 하는 불편함이 있다. 현재 대장CT검사 1회 시행의 평균유효선량은 약 8-10 $mS{\nu}$로 보고되어, 만약 이 검사가 많은 사람들을 대상으로 일상적으로 행해지면 공중보건에 영향을 미칠 수 있다. 따라서 집단검진 방법으로 정착하기 위해서 는 용종 크기 6-10 mm 범위에서 높은 민감도와 특이도를 확립하고, 하제를 사용하지 않는 방법을 개발하여야 하며, 선량을 더 감소시킬 수 있는 최적화된 전략을 세워 표준화하여야만 한다. 3. 전신CT검사는 그 효용성이 검증된 선행연구가 없는 상태이다. 이 검사는 약 90%의 검사자들에게서 최소한 하나 이상의 이상소견을 확인하였지만 그 중 약 2%만이 임상적으로 중요한 질환으로 판명되었다. 전신CT검사 1회 시행으로 인한 평균유효선량은 약 12 $mS{\nu}$이며 45세부터 75세까지 매년 검사를 받는 경우 LAR (lifetime attributable risk)이 1.9%로 보고되었다. 현재 의학계의 어떤 단체도 이 검사를 권고하고 있지 않다. 현재까지 CT선별검사는 정당화에 대한 충분한 논의를 위해 심도 있는 다양한 연구가 필요하며 최적화된 프로토콜이 확립된 후 이용하는 것이 바람직하다.