• Clinical and Experimental Reproductive Medicine
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• v.45 no.3
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• pp.143-148
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• 2018

Objective: The favored method of preserving fertility in young female cancer survivors is cryopreservation and autotransplantation of ovarian tissue. Reducing hypoxia until angiogenesis takes place is essential for the survival of transplanted ovarian tissue. The aim of this study was to investigate the role of angiopoietin-1 (Angpt-1), angiopoietin-2 (Angpt-2), and vascular endothelial growth factor (VEGF) in ovarian tissue grafts that were cryopreserved using two methods. Methods: Ovarian tissues harvested from ICR mice were divided into three groups: group I (control), no cryopreservation; group II, vitrification in EFS (ethylene-glycol, ficoll, and sucrose solution)-40; and group III, slow freezing in dimethyl sulfoxide. We extracted mRNA for VEGF, Angpt-1, and Angpt-2 from ovarian tissue 1 week following cryopreservation and again 2 weeks after autotransplantation. We used reverse transcriptase-polymerase chain reaction to quantify the levels of VEGF, Angpt-1, and Angpt-2 in the tissue. Results: Angpt-1 and Angpt-2 expression decreased after cryopreservation in groups II and III. After autotransplantation, Angpt-1 and Angpt-2 expression in ovarian tissue showed different trends. Angpt-1 expression in groups II and III was lower than in group I, but Angpt-2 in groups II and III showed no significant difference from group I. The vitrified ovarian tissues had higher expression of VEGF and Angpt-2 than the slow-frozen ovarian tissues, but the difference was not statistically significant. Conclusion: Our results indicate that Angpt-2 may play an important role in ovarian tissue transplantation after cryopreservation although further studies are needed to understand its exact function.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.4
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• pp.594-600
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• 2021

Curved beam structures are generally used as components in structures such as railroad bridges and vehicles. The stability analysis of curved beams has been studied by a large number of researchers. Due to the complexities of structural components, it is difficult to obtain an analytical solution for any boundary conditions. In order to overcome these difficulties, the differential quadrature method (DQM) has been applied for a large number of cases. In this study, DQM was used to solve the complicated partial differential equations for buckling analysis of curved beams. The governing differential equation was deduced and solved for beams subjected to uniformly distributed radial loads. Critical loads were calculated with various opening angles, boundary conditions, and parameters. The results of the DQM were compared with exact solutions for available cases, and the DQM gave outstanding accuracy even when only a small number of grid points was used. Critical loads were also calculated for the in-plane inextensional buckling of the asymmetric curved beams, and two theories were compared. The study of a beam with extensibility of the arch axis shows that the effects on the critical loads are significant.

• Journal of Conservation Science
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• v.34 no.6
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• pp.525-538
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• 2018

Myazedi Quadrilingual Stone Inscription of Myanmar, inscribed to the World Heritage List in 2015, is a rare historical artifact which has an exact date of inscription. It is a written record that displays the history, religion, and culture of Myanmar. Since the surface of the Stone Inscription has been rubbed with ink many times during the process of making printed copies for interpretation and academic research, it has developed a serious stain problem. Therefore, scientific analysis of the stain and research on the treatment for its removal have been conducted. In particular, an experiment was conducted on stain removal using laser cleaning and chemical treatment. The stains are mostly ink dirt, which accumulated from previous ink-rubbing processes. In order to conduct the experiment under similar conditions, a sample with similar stain has been reproduced, and a set of different conditions for treatment was applied to the sample to determine an effective solution. Laser cleaning was found to be effective in removing stains from most samples. However, chemical treatment showed different results. The physical friction method using ethanol provided the best result. In conclusion, laser cleaning is an effective universally-applicable technique but chemical treatment with laser cleaning can be considered an alternative method in certain situations.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.17 no.6
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• pp.40-53
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• 2018

In smart card data, movement of railway passengers appears in order of smart card terminal ID. The initial terminal ID holds information on the entering station's tag-in railway line, the final terminal ID the exit station tag-out railway line, and the middle terminal ID the transfer station tag subway line. During the past, when the metropolitan city rail consisted of three public corporations (Seoul Metro, Incheon Transit Corporation, and Korail), OD data was expressed in two metrics of initial and final smart card terminal ID. Recently, with the entrance of private corporations like Shinbundang Railroad Corporation, and UI Corporation, inclusion of entering transfer line terminal ID and exiting transfer line terminal ID as part of Chain OD has become standard. Exact route construction using Chain OD has thus become integral as basic data for revenue allocation amongst metropolitan railway transport corporations. Accordingly, path detection in railway networks has evolved to an optimal path detection problem using Chain OD, hence calling for a renewed solution method. This research proposes an optimal path detection method between the initial terminal ID and final terminal ID of Chain OD terminal IDs within the railway network. Here, private line transfer TagIn/Out must be reflected in optimal path detection using Chain OD. To achieve this, three types of link-based optimum path detection methods are applied in order of 1. node-link, 2. link-link, 3. link-node. The method proposed based on additional path costs is shown to satisfy the optimal conditions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.612-620
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• 2019

The increasing use of curved beams in buildings, vehicles, ships, and aircraft has results in considerable effort being directed toward developing an accurate method for analyzing the dynamic behavior of such structures. The stability behavior of elastic curved beams has been the subject of a large number of investigations. Solutions of the relevant differential equations have traditionally been obtained by the standard finite difference. These techniques require a great deal of computer time as the number of discrete nodes becomes relatively large under conditions of complex geometry and loading. One of the efficient procedures for the solution of partial differential equations is the method of differential quadrature. The differential quadrature method(DQM) has been applied to a large number of cases to overcome the difficulties of the complex algorithms of programming for the computer, as well as excessive use of storage due to conditions of complex geometry and loading. In this study, the in-plane extensional vibration for asymmetric curved beams with linearly varying cross-section is analyzed using the DQM. Fundamental frequency parameters are calculated for the member with various parameter ratios, boundary conditions, and opening angles. The results are compared with the result by other methods for cases in which they are available. According to the analysis of the solutions, the DQM, used only a limited number of grid points, gives results which agree very well with the exact ones.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.30 no.6
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• pp.270-285
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• 2018

The behavior of wave-induced pore water pressure inside the rubble mound and seabed, and the resultant structure failure are investigated, which are used in design of the composite breakwater representing the coastal and harbor structures. Numerical simulation techniques have been widely used to assess these behaviors through linear and nonlinear methods in many researches. While the combination of strongly nonlinear analytical method and turbulence model have not been applied yet, which can simulate these characteristics more accurately. In this study, olaFlow model considering the wave-breaking and turbulent phenomena is applied through VOF and LES methods, which gives more exact solution by using the multiphase flow analytical method. The verification of olaFlow model is demonstrated by comparing the experimental and numerical results for the interactions of regular waves-seabed and regular waves-composite breakwater-seabed. The characteristics of the spatial distributions of horizontal wave pressure, excess-pore-water pressure, mean flow velocity and mean vorticity on the upright caisson, and inside the rubble mound and seabed are discussed, as well as the relation between the mean distribution of vorticity size and mean turbulent kinetic energy. And the stability of composite breakwater are also discussed.

• Tunnel and Underground Space
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• v.31 no.1
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• pp.10-24
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• 2021

Rock mass classification for construction of underground facilities is essential to secure their stabilities. Therefore, the reliable values for rock mass classification from the precise information on rock discontinuities are most important factors, because rock mass discontinuities can affect exclusively on the physical and mechanical properties of rock mass. The conventional classification operation for rock mass has been usually performed by hand mapping. However, there have been many issues for its precision and reliability; for instance, in large-scale survey area for regional geological survey, or rock mass classification operation by non-professional engineers. For these reasons, automated rock mass classification using LiDAR becomes popular for obtaining the quick and precise information. But there are several suggested algorithms for analyzing the rock mass discontinuities from point cloud data by LiDAR scanning, and it is known that the different algorithm gives usually different solution. Also, it is not simple to obtain the exact same value to hand mapping. In this paper, several discontinuity extract algorithms have been explained, and their processes for extracting rock mass discontinuities have been simulated for real rock bench. The application process for several algorithms is anticipated to be a good reference for future researches on extracting rock mass discontinuities from digital point cloud data by laser scanner, such as LiDAR.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.9-17
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• 2021

Curved beams are increasingly used in buildings, vehicles, ships, and aircraft, which has resulted in considerable effort being directed toward developing an accurate method for analyzing the dynamic behavior of such structures. The stability behavior of elastic circular arches has been the subject of a large number of investigations. One of the efficient procedures for the solution of ordinary differential equations or partial differential equations is the differential quadrature method DQM. This method has been applied to a large number of cases to overcome the difficulties of the complex computer algorithms, as well as excessive use of storage due to conditions of non-linear geometries, loadings, or material properties. This study uses DQM to analyze the in-plane vibration of the circular arches considering the effects of midsurface extension and rotatory inertia. Fundamental frequency parameters are calculated for the member with various parameter ratios, boundary conditions, and opening angles. The solutions from DQM are compared with exact solutions or other numerical solutions for cases in which they are available and given to analyze the effects of midsurface extension and rotatory inertia on the frequency parameters of the circular arches.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.5A
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• pp.467-475
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• 2009

Existing studies have suggested Universal Curve only for supplemental damping by damper. Therefore net damping has been determined by means of arithmetic summation between intrinsic, aero-damping of cable and supplemental damping of damper. However linear combination approach by means of the arithmetic summation is not enough theoretical background. So validity of this approach should be verified in order to design adequate cable-damper system by engineers. This study establishes governing differential equation which can consider intrinsic, aero-damping and supplemental damping as well. And also analysis method is solved by combination of muller method and successive iteration method. Consequently, this study succeeds in verification for validity of linear combination approach. As a result of this study, linear combination approach is limitedly effective in case of low stiffness and optimum damping coefficient of damper, short distance from support to damper, lower vibration mode, low aero-damping, and normal windy environment. Whereas this study will be effective in case of opposite conditions, and existing studies or linear combination approach occur to further error. Meaning of this study presents exact solution for net damping of cable-damper system, and verifies linear combination approach by means of the analysis method. In the future, if monitoring of optimum damping coefficient of a damper against aero-damping is feasible on time, algorithm of this study will be available for control of cable and semi-active damper system such as magneto-rheological damper.

• Economic and Environmental Geology
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• v.41 no.6
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• pp.685-693
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• 2008

The rates of oxidative degradation of perchloroethene (PCE) and trichloroethene (TCE) using $KMnO_4$ solution were evaluated under the flow condition using a bench-scale transport experimental setup. Parameters which are considered to affect the reaction rates tested in this study were the contact time (or retention time), and the concentration of oxidizing agent. A glass column packed with coarse sand was used for simulating the aquifer condition. Contact time between reactants was controlled by changing the flow rate of the solution through the column. The inflow concentrations of PCE and TCE were controlled constant within the range of $0.11{\sim}0.21\;mM$ and $1.3{\sim}1.5\;mM$, respectively. And the contact time was $14{\sim}125$ min for PCE and $15{\sim}36$ min for TCE. The $KMnO_4$ concentration was controlled constant during experiment in the range of $0.6{\sim}2.5\;mM$. It was found that the reduction of PCE and TCE concentrations were inversely proportional to the contact time. The exact reaction order for the PCE and TCE degradation reaction could not be determined under the experimental condition used in this study. However, the estimated reaction rate constants assuming pseudo-1st order reaction agree with those reported based on batch studies. TCE degradation rate was proportional to $KMnO_4$ concentration. This was considered to be the result of using high inflow concentrations of reactant, which might be the case at the vicinity of the source zones in aquifer. The results of this study, performed using a dynamic flow system, are expected to provide useful information for designing and implementing a field scale oxidative removal process for PCE/TCE-contaminated sites.