• Title/Summary/Keyword: Event Characteristic

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Analysis of the Molecular Event of ICAM-1 Interaction with LFA-1 During Leukocyte Adhesion Using a Reconstituted Mammalian Cell Expression Model

  • Han, Weon-Cheol;Kim, Kwon-Seop;Park, Jae-Seung;Hwang, Sung-Yeoun;Moon, Hyung-Bae;Chung, Hun-Taeg;Jun, Chang-Duk
    • Animal cells and systems
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    • v.5 no.3
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    • pp.253-262
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    • 2001
  • Ligand-receptor clustering event is the most important step in leukocyte adhesion and spreading on endothelial cells. Intercellular adhesion molecule-1 (ICAM-1) has been shown to enhance leukocyte adhesion, but the molecular event during the process of adhesion is unclear. To visualize the dynamics of ICAM-1 movement during adhesion, we have engineered stable Chinese hamster ovary cell lines expressing ICAM-1 fused to a green fluorescent protein (IC1_GFP/CHO) and examined them under the fluorescence microscopy. The transfection of IC1_GFP alone in these cells was sufficient to support the adhesion of K562 cells that express $\alpha$L$\beta$2 (LFA-1) integrin stimulated by CBR LFA-1/2 mAb. This phenomenon was mediated by ICAM-1-LFA-1 interactions, as an mAb that specifically inhibits ICAM-1-LFA-1 interaction (RRl/l) completely abolished the adhesion of LFA-1* cells to IC1_ GFP/CHO cells. We found that the characteristic of adhesion was followed almost immediately (~10 min) by the rapid accumulation of ICAM-1 on CHO cells at a tight interface between the two cells. Interestingly, ICI_GFP/CHO cells projected plasma membrane and encircled approximately half surface of LFA-1+ cells, as defined by confocal microscopy. This unusual phenomenon was also confirmed on HUVEC after adhesion of LFA-1* cells. Neither cytochalasin D nor 2,3-butanedione 2-monoxime an inhibitor of myosin light chain kinase blocked LFA-1-mediated ICAM-1 clustering, indicating that actin cytoskeleton and myosin-dependent contractility are not necessary for ICAM-1 clustering. Taken together, we suggest that leukocyte adhesion to endothelial cells induces specialized form of ICAM-1 clustering that is distinct from immunological synapse mediated by T cell interaction with antigen presenting cells.

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Topic Similarity-based Event Routing Algorithm for Wireless Ad-Hoc Publish/Subscribe Systems (Ad-Hoc 무선 환경의 발행/구독 시스템을 위한 구독주제 유사도 기반의 이벤트 라우팅 알고리즘)

  • Nguyen, Hieu Trung;Oh, Sang-Yoon
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.10
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    • pp.11-22
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    • 2009
  • For a wireless ad-hoc network, event routing algorithm of the publish/subscribe system is especially important for the performance of the system because of the dynamic characteristic and constraint network of its own. In this paper, we propose a new hybrid event routing algorithm. TopSim for efficient publish/subscribe system on the wireless ad-hoc network by extending the ShopParent algorithm by considering not only network overheads to choose a Parent of the publish/subscribe tree, but also topic similarity which is closeness of subscriptions. Our evaluation shows our proposed TopSim performs better for the case where a new joining node subscribed to the multiple topics and there is a node among Parent candidate nodes who subscribe to the ones in the list of multiple topics (related topics).

A Study on the Expressional Characteristics of Contemporary Paintings and the Interior space in Rem Koolhaas's Architecture based on the Corporality (신체성에 기초한 현대 회화와 렘 콜하스 실내공간의 표현특성에 관한 연구)

  • Kim, Suk-Young;Kim, Moon-Duck
    • Korean Institute of Interior Design Journal
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    • v.18 no.6
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    • pp.85-95
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    • 2009
  • Since the early stages of philosophy in ancient Greece, reason has prevailed over sensation, based on the idea that it was the recognition of the ideal world existing as the archetype of objects. Abstract concepts followed geometric models, though they be invisible. However, from the beginning of 20th century, people began to be interested in the idea in metaphysical philosophy, that reason might not be a characteristic best representing the human spirit, and that a human being is composed of emotion, desire and the physical body, in addition to reason. The study shows that paintings and constructional space have shown similar changes through the stream of time, and have a synchronistic relationship within the range of the formative arts, based on the contemporary philosophy. First of all, it defines the change of contemporary thought and its analysis words. And consider the Corporality which is one characteristic of contemporary thought. This study shows the characteristic of the Corporality in the architectural space of Rem Koolhaas whom it selected the architecture who is influenced by Post-structuralism. In conclusion, It compares paintings and architectural space and looks into the correlations among them in the category of the Corporality which is a pont of view from contemporary thought. As a result of the comparison, the Corporality in paintings is defined as (1) An escape form Reason, (2) An emphasis of experienced events and (3) A destruction of forms. It defines the architectural space of Rem Koolhaas corresponding with the Corporality in paintings has a characteristic of (1) The space of Body without Organs, (2) Becoming spatial concept of events and (3) An Unrestrained Form.

The Works of John Galliano in Haute Couture - With a Focus on C. Dior in 20005 - (Haute Couture에 나타난 John Galliano의 작품세계 -2000년대 C. Dior 중심으로-)

  • Bang, Soo-Ran
    • Journal of the Korean Society of Costume
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    • v.59 no.5
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    • pp.19-40
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    • 2009
  • The purpose of this study is to grasp the world of Galliano works who lead Dior Couture and to make use of this knowledge to comprehension of general trend in Haute Couture and $pr{\hat{e}}t-{\acute{a}}$-porter in the future. The method of research is to search for the characteristic of Haute Couture and the general tendency of Galliano works, and to view the inclination of Dior Couture by Galliano. For sphere of research, 2000s is discussed with focus on Haute Couture, exclusive of ready-to-wear. As a result, Galliano's Couture works were distinguished into four specificities. First, the historicity including historical event, personage and epoch. Second, the orientalism. Third, the pictorial characteristic including synthetic art and public art. Forth, the quality of humor. These subjects bring about a result that break down each boundary, in the method of interpreting, as try out mixing between every elements. Galliano pursue a new domain through the fusion of East and West, past and present, classic and pop, artistry and commercialism, this induce more familiar Haute Couture to the public, breaking the strict form of Couture. It seems that this tendency will be advanced toward extrovert Couture producing the low-age phenomenon in Couture, the mixture of multi-culture and the vitality. This fusion suggest the popularity and the commerciality of Couture, which is predicted decrease the difference between Couture and $pr{\hat{e}}t-{\acute{a}}$-porter.

Characteristic wave detection in ECG using complex-valued Continuous Wavelet Transforms

  • Berdakh, Abibullaev;Seo, Hee-Don
    • Journal of Biomedical Engineering Research
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    • v.29 no.4
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    • pp.278-285
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    • 2008
  • In this study the complex-valued continuous wavelet transform (CWT) has been applied in detection of Electrocardiograms (ECG) as response to various signal classification methods such as Fourier transforms and other tools of time frequency analysis. Experiments have shown that CWT may serve as a detector of non-stationary signal changes as ECG. The tested signal is corrupted by short time events. We applied CWT to detect short-time event and the result image representation of the signal has showed us that one can easily find the discontinuity at the time scale representation. Analysis of ECG signal using complex-valued continuous wavelet transform is the first step to detect possible changes and alternans. In the second step, modulus and phase must be thoroughly examined. Thus, short time events in the ECG signal, and other important characteristic points such as frequency overlapping, wave onsets/offsets extrema and discontinuities even inflection points are found to be detectable. We have proved that the complex-valued CWT can be used as a powerful detector in ECG signal analysis.

A Study of Art Marketing Using Korean Features (한국적 요소를 활용만 아트마케팅 현황 고찰)

  • Hong, Jung-Young;Park, Eun-Kyung
    • Journal of the Korean Society of Costume
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    • v.59 no.7
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    • pp.140-153
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    • 2009
  • In the 21st century called an age of culture and art beyond the information and technology, many companies are developing various art marketings. Cases of the art marketing especially utilizing Korean features among art marketings are being increased recently. It is creating new values as a characteristic based on the cultures value of Korea. This thesis examined cooperative product development focusing on collaborative trends between designers, artists and companies through research on product and art marketing using Korean features. Additionally, by studying features of culture promotional event including exhibition and contest sponsorship, advertisement and packaging and the meaning of futures art marketing were discussed. Though, to date, academic researches have not been thoroughgoing enough in this field, it is considered that cultural product commercializing cultural particularity can strengthen the national image with acknowledgement of the global value as the art marketing using Korean features can contribute to improve recognition and the national image. Based upon this study, the value of Korean features on which custom culture of Korea dwells will be able to give a help to the designer and artist for progressing collaboration with companies as well as the companies for introducing new cultural characteristic to marketing, in the future-proof point of view. Additionally, it will be able to help the government planning the policy for intensifying the national image as a reference.

Damping BGP Route Flaps

  • Duan, Zhenhai;Chandrashekar, Jaideep;Krasky, Jeffrey;Xu, Kuai;Zhang, Zhi-Li
    • Journal of Communications and Networks
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    • v.9 no.4
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    • pp.490-498
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    • 2007
  • BGP route flap damping(RFD) was anecdotally considered to be a key contributor to the stability of the global Internet inter-domain routing system. However, it was recently shown that RFD can incorrectly suppress for substantially long periods of time relatively stable routes, i.e., routes that only fail occasionally. This phenomenon can be attributed to the complex interaction between BGP path exploration and how the RFD algorithm identifies route flaps. In this paper we identify a distinct characteristic of BGP path exploration following a single network event such as a link or router failure. Based on this characteristic, we distinguish BGP route updates during BGP path exploration from route flaps and propose a novel BGP route flap damping algorithm, RFD+. RFD+ has a number of attractive properties in improving Internet routing stability. In particular, it can correctly suppress persistent route flaps without affecting routes that only fail occasionally. In addition to presenting the new algorithm and analyzing its properties, we also perform simulation studies to illustrate the performance of the algorithm.

Keyword Filtering about Disaster and the Method of Detecting Area in Detecting Real-Time Event Using Twitter (트위터를 활용한 실시간 이벤트 탐지에서의 재난 키워드 필터링과 지명 검출 기법)

  • Ha, Hyunsoo;Hwang, Byung-Yeon
    • KIPS Transactions on Software and Data Engineering
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    • v.5 no.7
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    • pp.345-350
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    • 2016
  • This research suggests the keyword filtering about disaster and the method of detecting area in real-time event detecting system by analyzing contents of twitter. The diffusion of smart-mobile has lead to a fast spread of SNS and nowadays, various researches based on studying SNS are being processed. Among SNS, the twitter has a characteristic of fast diffusion since it is written in 140 words of short paragraph. Therefore, the tweets that are written by twitter users are able to perform a role of sensor. By using these features the research has been constructed which detects the events that have been occurred. However, people became reluctant to open their information of location because it is reported that private information leakage are increasing. Also, problems associated with accuracy are occurred in process of analyzing the tweet contents that do not follow the spelling rule. Therefore, additional designing keyword filtering and the method of area detection on detecting real-time event process were required in order to develop the accuracy. This research suggests the method of keyword filtering about disaster and two methods of detecting area. One is the method of removing area noise which removes the noise that occurred in the local name words. And the other one is the method of determinating the area which confirms local name words by using landmarks. By applying the method of keyword filtering about disaster and two methods of detecting area, the accuracy has improved. It has improved 49% to 78% by using the method of removing area noise and the other accuracy has improved 49% to 89% by using the method of determinating the area.

Development of methodology for daily rainfall simulation considering distribution of rainfall events in each duration (강우사상의 지속기간별 분포 특성을 고려한 일강우 모의 기법 개발)

  • Jung, Jaewon;Kim, Soojun;Kim, Hung Soo
    • Journal of Korea Water Resources Association
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    • v.52 no.2
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    • pp.141-148
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    • 2019
  • When simulating the daily rainfall amount by existing Markov Chain model, it is general to simulate the rainfall occurrence and to estimate the rainfall amount randomly from the distribution which is similar to the daily rainfall distribution characteristic using Monte Carlo simulation. At this time, there is a limitation that the characteristics of rainfall intensity and distribution by time according to the rainfall duration are not reflected in the results. In this study, 1-day, 2-day, 3-day, 4-day rainfall event are classified, and the rainfall amount is estimated by rainfall duration. In other words, the distributions of the total amount of rainfall event by the duration are set using the Kernel Density Estimation (KDE), the daily rainfall in each day are estimated from the distribution of each duration. Total rainfall amount determined for each event are divided into each daily rainfall considering the type of daily distribution of the rainfall event which has most similar rainfall amount of the observed rainfall using the k-Nearest Neighbor algorithm (KNN). This study is to develop the limitation of the existing rainfall estimation method, and it is expected that this results can use for the future rainfall estimation and as the primary data in water resource design.

A Function-characteristic Aware Thread-mapping Strategy for an SEDA-based Message Processor in Multi-core Environments (멀티코어 환경에서 SEDA 기반 메시지 처리기의 수행함수 특성을 고려한 쓰레드 매핑 기법)

  • Kang, Heeeun;Park, Sungyong;Lee, Younjeong;Jee, Seungbae
    • Journal of KIISE
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    • v.44 no.1
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    • pp.13-20
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    • 2017
  • A message processor is server software that receives various message formats from clients, creates the corresponding threads to process them, and lastly delivers the results to the destination. Considering that each function of an SEDA-based message processor has its own characteristics such as CPU-bound or IO-bound, this paper proposes a thread-mapping strategy called "FC-TM" (function-characteristic aware thread mapping) that schedules the threads to the cores based on the function characteristics in multi-core environments. This paper assumes that message-processor functions are static in the sense that they are pre-defined when the message processor is built; therefore, we profile each function in advance and map each thread to a core using the information in order to maximize the throughput. The benchmarking results show that the throughput increased by up to a maximum of 72 % compared with the previous studies when the ratio of the IO-bound functions to the CPU-bound functions exceeds a certain percentage.