• Natural Product Sciences
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• v.6 no.4
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• pp.183-188
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• 2000

In order to discover novel potent antitumor agents, methanolic extracts of approximately 180 herbal medicines were prepared and primarily evaluated for cytotoxic activity in cultured human lung (A549) and colon (Col 2) cancer cells. As a result, 17 natural product extracts were found to be active in the criteria of $IC_{50}$<$20\;{\mu}g/ml$. Especially, the extracts of Aristolochia debilis, Cynanchum ascyrifolium, Cynanchum paniculatum, Daphne genkwa, Euphorbia lathyris, Ipomoea hederacea, Magnolia officinalis, Melia azedarach var. japonica, Solanum nigrum, Thuja orientalis, and Trichosanthes kirilowii showed a strong cytotoxic potential. The flower extract of Daphne genkwa was more selective cytotoxic activity against lung cancer cells $(IC_{50};\;0.2\;{\mu}g/ml)$ compared to colon cancer cells $(IC_{50}>20\;{\mu}g/ml)$. In addition, based on the cytotoxic potential of the root extract of Cynanchum paniculatum, the further fractionation of methylene chloride partition with silica gel column chromatography was performed. Several subfractions were considered to be active, and thus indicating that further studies for the identification of active principles from these fractions might be warranted.

• Natural Product Sciences
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• v.12 no.1
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• pp.29-37
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• 2006

One hundred and twenty six Vietnamese traditional herbals belonging to 59 families were screened for their free radical (DPPH) scavenging activity and inhibitory effect on lipid peroxidation. Of these, MeOH extracts of seven plants, including Euphorbia thymifolia (leaf), Gnetum montanum (stem), Heterosmilax erythrantha (root), Morus alba (leaf), Syzygium formosum (leaf), Jussiaea repens (aerial parts), and Camellia sinensis (leaf), exhibited significant antioxidant activities. All of these herbs showed remarkable free radical scavenging activities with $IC_{50}$ values of 11.0, 14.5, 17.0, 13.6, 10.8, 7.7, and $8.5\;{\mu}g/ml$, respectively, and significant inhibitory effects on lipid peroxidation with 79.7, 83.8, 78.9, 82.5, 88.8, 88.0, and 96.2% inhibitions, respectively, at the concentration of $50\;{\mu}g/ml$.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.9 no.3
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• pp.59-75
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• 2006

The vascular plants of this site was listed 360 taxa; 86 families, 229 genera, 311 species, 42 varieties and 7 forms. Specific plant species by floral region were total 40 taxa; 2 taxa(Crypsinus hastatus, Prunus yedoensis) in class V, Patrinia rupestris in class IV, 6 taxa(Elymus mollis, Carex laticeps, Poncirus trifoliata, Melia azedarach var. japonica, Koelreuteria paniculata, Crepiastrum lanceolatum) in class III, Cirsium schantarense in class II, 30 taxa(Lygodium japonicum, Pteris multifida, Phacelurus latifolius, Asparagus cochinchinensis, Ficus erecta, Machilus thunbergii, Zanthoxylum planispinum, Euphorbia esula, Mallotus japonicus, Cayratia japonica, Camellia japonica, Glehnia littoralis, Lysimachia fortunei, Messerschmidia sibirica, Ixeris repens etc.) in class I. The naturalized plants in this site were 14 families, 34 genera, 41 species, 1 varieties, 42 taxa and naturalization rate was 20.3% of all 207 taxa vascular plants. Based on the list of the rare plants by the Forest Research Institute, 2 taxa were recorded in the studied areas; Phacelurus latifolius, Crypsinus hastatus and based on the list of Korean endemic plants, 7 taxa were recorded; Populus tomentiglandulosa, Filipendula glaberrima, Prunus yedoensis, Forsythia koreana, Paulownia coreana, Weigela subsessilis, Carpinus coreana. So, wild plants disturbing ecosystem like Solanum carolinense and Ambrosia artemisiifolia var. elatior have been increasing, it needs continuing control and conservation measures on the plant ecosystem.

• Horticultural Science & Technology
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• v.17 no.5
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• pp.581-583
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• 1999

This experiment was conducted to investigate the effects of uniconazole drench treatment on the growth and flowering of poinsettia and to suggest proper application dosage and time. Plant height, branch length, and leaf area were significantly restricted as the concentration of uniconazole increased. Application doses of 0.05 and 0.10 mg/pot effectively controlled the growth of poinsettia 'V-10 Amy'. Earlier soil drench of uniconazole resulted in more effective reduction in plant height, branch length, and leaf area. In all cases, no noticeable phytotoxicity by plant growth retardants tested was observed.

• The Journal of Internal Korean Medicine
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• v.37 no.6
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• pp.1051-1058
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• 2016

Objectives: This case study reports on a case of rhabdomyolysis that occurred after spinning exercise. Methods: A patient diagnosed with rhabdomyolysis received Korean medical treatment and Western medical treatment for 6 days. We observed the patient for 13 days. Clinical symptoms were evaluated with the Numerical Rating Scale (NRS) and laboratory tests that included Liver Function Test, Renal Function Test, creatinine phosphokinase (CPK), myoglobin, and urine. Results: The clinical symptoms improved after treatment. In this case, acute renal failure has not occurred. The Laboratory results, including AST, ALT, CPK, and LDH, improved. Conclusions: Rhabdomyolysis can be treated with Korean medical and Western medical cooperative treatment.

• The Journal of Internal Korean Medicine
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• v.38 no.5
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• pp.681-688
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• 2017

An obese patient was treated with Korean medicine for a short-term period of seven days while under admission care. In this case report, we report the efficacy of a complex treatment comprising various Korean medicine methods by evaluating the differences in obesity-linked factors. The patient lost weight loss and showed decreases in fat mass and various indexes of obesity. Korean medicine could therefore represent a prompt and effective treatment for obese patients.

• Korean Journal of Pharmacognosy
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• v.28 no.1
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• pp.15-20
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• 1997

This study was carried out to investigate the antioxidative activities of domestic plants grown in the area of Kangwon-do province. Through the examination of methanol extracts from 15 plants for radical scavenging effects using DPPH method, the extracts from Pinus densiflora Sieb. et Zucc. And Euphorbia humifusa Willd. Showed strong antioxidative activity. Because of its highest antioxidative activity among 15 domestic plants, radical scavenging effects of four different extract compartments from leaves of P.densiflora, n-Hexane, EtOAc, BuOH and $H_2O$ extracts. Were examined by DPPH method. Antioxidative activities of EtOAc and BuOH extracts were similar or even higher than that of natural (tocopherol) or synthetic antioBfdants (BHA) , suggesting that major fraction for the antioxidative activity of P. densiflora was the EtOAc and BuOH extract compartments.

• Korean Journal of Plant Resources
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• v.28 no.4
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• pp.511-525
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• 2015

The purpose of this study is to offer the flora data for conserving the biodiversity of Gyeongju National Park by objective surveying and analysing the flora distributed in Mt. Gumi District, Gyeongju National Park, South Korea. The flora of Mt. Gumi were surmmarized as 476 taxa including 97 families, 297 genera, 419 species, 3 subspecies, 46 varieties and 8 forms. The rare plants were 6 taxa such as Aristolochia contorta, Paeonia lactiflora var. trichocarpa, Potentilla discolor, Berchemia berchemiaefolia, Trigonotis icumae and Iris odaesanensis. The Korean endemic plants were 9 taxa such as Carpinus laxiflora, Pseudostellaria coreana, Philadelphus schrenkii, Indigofera koreana, Lespedeza maritima, Vicia chosenensis, Galium koreanum, Lonicera subsessilis and Weigela subsessilis. The specific plants by floristic region were 38 taxa such as Salix chaenomeloides(I), Hylomecon vernalis (I), Oxalis obtriangulata (I), Viola orientalis(II), Adoxa moschatellina (II), Cirsium chanroenicum (II), Vitex negundo var. incisa (III) and so forth. The naturalized plants were 36 taxa such as Fallopia dumetorum, Chenopodium album, Lepidium virginicum, Amorpha fruticosa, Euphorbia supina, Carduus crispus, Erigeron strigosus, Festuca myuros and so forth. The invasive aline plant was Aster pilosus. The target plants adaptable to climate change were 8 taxa such as Artemisia rubripes, Carpesium macrocephalum and so forth.

• Journal of Medicine and Life Science
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• v.15 no.2
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• pp.72-78
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• 2018

We investigated the effect of KIOM-79, 80% ethanolic extract of herbal prescription isolated from Magnolia officinalis, Pueraria lobate, Glycyrrhiza uralensis, and Euphorbia pekinensis, on streptozotocin-induced diabetes in Sprague-Dawley rats. The rats were treated orally with KIOM-79 (500 mg/kg/day) 1) for 3 days prior to streptozotocin (60 mg/kg, intraperitoneal) injection or 2) for 9 weeks after establishing diabetes model to examine acute and chronic effects on hyperglycemia and biochemical variables, respectively. As a result, KIOM-79 had little effects on hyperglycemic changes in acute model. Sexual comparison, however, showed reduced hyperglycemia in female rats, especially 24 hours after streptozotocin injection with or without KIOM-79 pretreatment. In chronic model, streptozotocin-induced hyperglycemia was well established, but KIOM-79 treatment showed no statistically significant effects on all variables. Thus, based on our findings KIOM-79 might have little effects on streptozotocin-induced insulin-dependent diabetes although it has been known to have hypoglycemic and antidiabetic effects on non-insulin-dependent diabetes models.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.23 no.6
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• pp.87-107
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• 2020

The purpose of this study is to present the basic data for maintenance and management of river ecosystem by surveying and analysing the kinds and their characteristics of vascular plants in Bukcheon stream, Gyeongju-si, South Korea. The numbers of vascular plants were summarized as 428 taxa including 92 families, 265 genera, 3 subspecies, 24 varieties, 6 forms, 5 hybrids and 5 cultivars. Among the identified taxa, there were 90 planted species. The endangered wild species was Cicuta virosa, and the rare plants were 5 taxa including Prunus × yedoensis, Juniperus chinensis L. var. sargentii and so on. The Korean endemic plants were 5 taxa Populus × tomentiglandulosa, Salix koriyanagi, Lespedeza maritima, Forsythia koreana and Aster pseudoglehni. The specific plants by floristic region were 26 taxa including 2 taxa of grade V, 3 taxa of grade IV, 2 taxa of grade III, 8 taxa of grade II and 11 taxa of grade I. The naturalized plants were 81 taxa including Euphorbia maculata, Erigeron strigosus, Vulpia myuros and so on. The invasive alien plants were 7 taxa including Humulus scandens, Rumex acetosella, Ambrosia artemisiifolia, Ambrosia trifida, Lactuca seriola, Symphyotrichum pilosum and Paspalum distichum.