• 중환자간호학회지
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• 제16권1호
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• pp.56-70
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• 2023

Purpose : This study aimed to identify the effects of a multifaceted pediatric delirium education program for pediatric intensive care unit (PICU) nurses on their delirium knowledge, confidence in delirium nursing, and delirium evaluation accuracy. Methods : This study used a one-group pretest-posttest design. The participants were 50 nurses in two units of the PICU at S General Hospital in Seoul. All participants took a 1-hour lecture with case-based practice for the first two weeks, and received feedback as they applied the program to clinical practice over the next two weeks. Test measures were completed before and after the four week intervention period for all participants. The delirium evaluation accuracy was measured using the Korean version of the Cornell Assessment of Pediatric Delirium. Data were analyzed using the chi-square and paired t-tests. Results : After the Pediatric Delirium Education Program, nurses' delirium knowledge (x²=11.65, p =.001), confidence in delirium nursing (t=9.71, p<.001), and delirium evaluation accuracy (t=6.07, p<.001) improved significantly. Conclusions : Pediatric delirium education programs for PICU nurses were effective. For active application of the program in clinical practice in the future, various cases of childhood delirium and specific strategies for each subject must be developed. To achieve this, long-term intervention and research for multiple organizations are required.

• 임상간호연구
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• 제29권1호
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• pp.67-74
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• 2023

Purpose: This study aimed to identify the effect of warm scarf on xerostomia and sore throat in postoperative colon cancer patients. Methods: A total of 40 participants with colon cancer who underwent colon cancer operation over 2hours were included from C University hospital in Seoul. The number of experimental group and control group is each 20 calculated by G*Power, and they were assigned by using nonequivalent control group no-synchronized design. In the experimental group, a warm scarf was applied to the neck for 120 minutes from entering the recovery room after the colorectal cancer surgery was completed. In the experimental group and the control group, xerostomia and sore throat were measured twice at 60-minute intervals. The degree of xerostomia was measured through the degree of wetness of the absorbent paper in mm, and the degree of sore throat was measured through the NRS (Numeral Rating Scale). Data were collected using self-administered questionnaires from August 2018 to September 2020 and were analyzed using IBM SPSS/WIN 21.0 Descriptive statistics, x² test, Fisher's exact test, t-test were used to determine the participant's characteristics. The effect of warm scarf on xerostomia and sore throat were separately estimated by Repeated Measures ANOVA. Results: The experimental group showed significant decrease of xerostomia and sore throat as time goes (p<.001). Conclusion: Results indicate that warm scarf on xerostomia and sore throat in postoperative colon cancer patients is helpful method for relieving side effect of tracheal intubation.

• Journal of Ginseng Research
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• 제47권3호
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• pp.385-389
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• 2023

Background: Ginseng has been used as a traditional medicine for treatment of many diseases and for general health maintenance. Previously, we showed that ginseng did not demonstrate estrogenic property in ovariectomized mouse model. However, it is still possible that disruption of steroidogenesis leading to indirect hormonal activity. Methods: The hormonal activities were examined in compliance with OECD guidelines for detecting endocrine disrupting chemicals: test guideline (TG) No. 456 (an in vitro assay method for detecting steroidogenesis property) and TG No. 440 (an in vivo short-term screening method for chemicals with uterotrophic property). Results: Korean Red Ginseng (KRG) and ginsenosides Rb1, Rg1, and Rg3 did not interfere with estrogen and testosterone hormone synthesis as examined in H295 cells according to TG 456. KRG treatment to ovariectomized mice did not show a significant change in uterine weight. In addition, serum estrogen and testosterone levels were not change by KRG intake. Conclusion: These results clearly demonstrate that there is no steroidogenic activity associated with KRG and no disruption of the hypothalamic-pituitary-gonadal axis by KRG. Additional tests will be performed in pursuit of cellular molecular targets of ginseng to manifest mode of action.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2022년도 추계학술대회
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• pp.257-257
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• 2022

Late blight, caused by the hemibiotrophic oomycete pathogen Phytophthora infestans, has been the most important disease limiting potato production worldwide. P. infestans undergo major population shifts in agricultural systems via the successive emergence and migration of asexual lineages. The phenotypic and genotypic bases of these selective sweeps are largely unknown but management strategies need to adapt to reflect the changing pathogen population. Here, we used molecular markers to divide the 86 South Korea isolates into six clonal lineages: KR_1_A1, KR_2_A2, SIB-1, US-11, SIB-1 like, and KR-2 like. We documented the emergence of a new lineage, termed SIB-1 like, and KR-2 like, and their rapid replacement of other lineages to exceed 35% of the pathogen population across South Korea. Genome analyses of the Korean P. infestans populations revealed extensive genetic polymorphism, particularly in effector genes. Importantly, SIB-1 like isolates carry an intact Avr8 effector gene that triggers resistance in potato carrying the corresponding R immune receptor gene R8 cloned from Solarium demissum. These findings point toward a strategy for deploying genetic resistance to mitigate the impact of the SIB-1 like lineage and illustrate how pathogen population monitoring, combined with genome analysis, informs the management of devastating disease epidemics. Further study is being done on pathogenicity of the SIB-1 like isolates on cultivated potatoes and changes in expression patterns of disease effector genes within the SIB-1 like isolates

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2023년도 임시총회 및 춘계학술대회
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• pp.5-5
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• 2023

감자(Solanum tuberosum L.)는 식물학적 분류상으로 가지과에 속하는 작물로, 재배기간이 짧고 단위면적당 생산량이 많아 세계적으로 벼, 밀, 옥수수에 이어 네 번째로 재배되고 있다. 감자의 원산지는 남아메리카 안데스 산맥의 고원지대로 유럽을 거쳐 여러 나라들로 퍼져나갔으며, 1824년경 우리나라로 감자가 들어왔다는 기록이 남아있다. 국내 감자 재배작형 비율을 살펴보면, 봄재배가 63%, 여름재배 16%, 가을감자 14%, 그리고 겨울시설재배가 7% 정도를 차지하고 있으며 소비자들에게 연중 햇감자를 공급하고 있다. 1960년대부터 국내에서 감자 교배육종을 시작하면서 육종기반을 구축하였으며 현재까지 40여 품종을 육성하였다. 과거에는 부족한 주식을 대체하기 위한 구황작물로 감자를 주로 소비하였기 때문에, 식용감자 품종 위주로 선발하기 위하여 조숙성과 수량성에 중점을 두어 '조풍', '추백' 등의 품종을 육성하여 보급하였다. 최근 국민 소득의 향상과 식습관 변화 등으로 식품 소비구조가 다양화되면서 감자를 식용뿐만 아니라 감자칩, 프렌치프라이 등 가공제품이나 더 나아가 화장품 원료로 이용되면서 육종 방향과 목표를 다양하게 설정하여 품종을 육성하고 있다. 그 결과로, 전분함량이 높고 칩가공성이 우수한 '다미', '골든볼', '은선' 등 칩가공용 품종, 감자모양이 길고 건물함량이 높아 가공적성이 우수하고 프렌치 프라이로 적합한 '골든에그'와 '얼리프라이', 기형, 열개 등 생리장해 발생이 적고 일반 부식용인 '수선', '추원' 등 다양한 용도를 가진 품종을 육성하여 보급하고 있다. 이와 같이 현재까지 육성된 감자 용도별 주요 품종들의 현황과 육종 방향에 대해서 소개하고자한다.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 춘계학술대회
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• pp.32-32
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• 2020

High-quality and high-phytonutrient watermelon fruits have strong market opportunities besides their health related benefits. Hence, investigating quality and nutritional related traits of watermelon genetic resources could provide important baseline data in breeding for increased lycopene content thereby increasing the marketability of watermelon. To this end, we have examined some fruit morphological traits and lycopene content of 105 genetic resources. The morphological characters were recorded on the field and inside laboratory and lycopene was measured using spectrophotometric and HPLC methods. Watermelon fruits have shown a diverse morphological characters. Red and pink fleshed fruits dominated in the entire collections. Fruits with higher thickness of rind were found to exhibit less soluble solid content (SSC). Korean origin fruits were characterized by intermediate SSC while USA, RUS, TJK, TKM, TWN, and URY originated fruits had the highest SSC. The lycopene content varied between 41.37 and 182.82 ㎍/g, 2.81 and 163.72 ㎍/g, and 3.54 and 255.47 ㎍/g using HPLC, UV-Vis, and microplate reader instrumnets, respectively. Red- and pink-fleshed fruits had the highest levels of lycopene content compared to the yellow- and orange-fleshed. Lycopene content had a significant positive correlation with SSC, however, no correlations were detected between lycopene and other quantitative fruit morphological characters.

• The Journal of Advanced Prosthodontics
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• 제16권4호
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• pp.255-266
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• 2024

PURPOSE. This study aimed to evaluate the clinical performance of implant-assisted removable partial dentures (IARPD) with surveyed crowns, also known as implant-crown-retained removable partial dentures (ICRPDs). MATERIALS AND METHODS. Electronic searches of MEDLINE/PubMed, the Cochrane Central Register of Controlled Trials, the Web of Science, and the Korea Citation Index were performed according to the established search terms for ICRPD. A literature search was conducted for studies published in English or Korean until September 2023, using the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. RESULTS. A total of 216 journals were searched, and 31 eligible studies were selected based on the inclusion and exclusion criteria. One systematic review included five case reports of ICRPD. Nine retrospective studies evaluated implant survival/success rate, implant failure cases, marginal bone loss, periodontal status, clinical complications, and patient satisfaction. Twenty-one case reports published in Korea showed good prognoses. CONCLUSION. According to the findings of this systematic review, ICRPD has a reasonable survival/success rate, minimal bone loss, and high patient satisfaction.

• 생명과학회지
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• 제27권10호
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• pp.1111-1120
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• 2017

내습성 및 감수성 선발계통 각 1점씩을 대상으로 침수처리 후 GO 분석을 통해 추출된 유전자들을 기능별로 분류해보면 생물학적 과정(biological process)에 관여하는 유전자 발현이 가장 크게 영향을 받았으며, 분자 기능(molecular function)과 세포 요소(cellular component) 관련 유전자를 포함하여 모든 기능의 유전자 발현 변화가 감수성 계통보다 내습성 계통에서 크게 일어났다. 침수처리 후 발현 양상이 유의하게 차이나는 유전자의 보다 자세한 기능을 측정한 결과 내습성 계통에서 발현량이 증가한 유전자는 CA02g26670은 CONSTANS protein과 관련있는 유전자로 일장조건에 따른 개화조절에 관여하는 유전자이며, 발현량이 감소한 유전자는 CA01g21450, CA01g22480, CA01g34470, CA02g00370, CA02g00380이었다. 감수성 계통에서 침수처리 후 발현량이 증가한 유전자는 CA02g09720, CA02g21290, CA03g16520, CA07g02110, CA12g17910이었는데 각각 단백질 분해효소 활성 저해, DNA binding, 세포벽 분해효소 억제, nodulin 관련 유전자 등으로 밝혀진 유전자들이었다. 감수성 계통에서 발현량이 감소한 유전자는 CA02g02820, CA03g21390, CA06g17700, CA07g18230로 각각 칼슘이온결합, 고온환경 발현기작, 레시틴 생합성 경로의 수용성중간대사체인 phosphocholine 합성 및 저온스트레스 관련 등의 기능을 한다. 내습성 계통과 감수성 계통에서 동시에 발현이 증가한 유전자는 고온 등 환경스트레스로 인한 apoptosis와 관련된 유전자와 peroxidase와 관련있는 유전자로 확인되었고, 발현이 동시에 감소한 유전자는 nucleoside transporter인 CA02g16990로 확인되었으며, 나머지 선발 유전자는 유전자 발현이 확인되지 않았다. 내습성 및 감수성 계통간 습해 조건에서 발현에 차이를 보이는 유전자 구명을 기반으로 향후 불량환경에 대해 저항성을 보이는 계통 육성 및 관련 생리반응에 대한 다양한 연구가 필요하다.

• 기본간호학회지
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• 제11권2호
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• pp.124-137
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• 2004

Purpose: The purpose of this study was to examine differences in the perceived importance and frequency of nurse role behaviors for medical and surgical nurses and to examine the relationship between perceived importance and frequency of nurse role behaviors in the two groups. Method: A descriptive design was used with convenience sampling of 351 medical and surgical nurses in the 40 hospitals with over 500 beds. Data were collected using a structured questionnaire. Results: 1) The total score for perceived importance of nurse role behaviors was $4.09{\pm}.53$ for medical nurses and $4.13{\pm}.53$ for surgical nurses. 2) The total score for frequency was $3.15{\pm}.54$ for medical nurses and $3.24{\pm}.56$ for surgical nurses. 3) The perceived importance of nurse role behaviors was higher than the frequency, but the difference between two groups was not significant. 4) The perceived importance of nurse role behaviors was highly correlated with frequency (r=.579, p=.000) for the two groups. Conclusion: Medical and surgical nurses perceived the importance nurse role behavior but the frequency of the behavior is lower. Therefore, further research is needed to develop strategies to increase the frequency of nurse role behaviors.

• Journal of Nutrition and Health
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• 제14권4호
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• pp.190-199
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• 1981

A survey of nutrition and incidence of parasites was conducted from January 23 to 31 and February 14 to 18, 1981, to determine the nutritional status of young children under the age of 6 years, in one of the rural family health project areas: Whaseoung-gun, Kyunggi-do, Korea. This study covered a total of 233 children. The results are summarised as follows: Approximately one-half of these families had an annual income between \1,000,000 and \2,500,000. Nearly 84% of the households were involved in farming. Energy intake of children met 70.6% of the requirement: carhohydrates provided 77%, protein provided 11%, and fat provided 12% of the total energy intake. Low intake of iron; calcium; and vitamins, excluding thiamin, was also found. Mean hemoglobin value was $10.6{\pm}1.0gm/100ml.;\;42%$ of subjects were categorized as low group, 22% were in the deficient group, and only 36% were at an acceptable level as indicated by O'Neal. Thus, 22% of the subjects were proven to be anemic by the hemoglobin criteria. Mean hematocrit value was $30.1{\pm}2.8%$, and 80 of 208 children, or 38.4% of subjects, were below 30% of the standard established by O'Neal. The positive prevalence of parasitic infection was 20% , significantly higher than that observed in the Yowido compound (5.5%) in 1980. Hematologic findings had no significant correlation to parasitic infection. The majority, 95.2% of the subjects, met or surpassed 90% of the KlST's standard of height:whtile 28. 6% of the subjects were below 90% of the KIST's standard of weight. The ratio of weight to height for boys 4 to 6 years old was 15.8 to 17.5, in contrast to 16.3 to 16.9 for boys of KHDI project areas, and also in contrast to 17.7 to 17.9 for boys of the same age group from the Yowido apartment compound in Seoul. According to the results of the assessments, the authors found a clear difference in growth values, hematologic findings and dietary patterns between rural areas and advantaged urban areas of Seoul. Our results suggest the need to develop the nutrition and parasite control training of village women for better nutritional care of their young children.