• 제목/요약/키워드: Ets-1

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Linking growth performance and carcass traits with enterotypes in Muscovy ducks

  • Qian Fan;Yini Xu;Yingping Xiao;Caimei Yang;Wentao Lyu;Hua Yang
    • Animal Bioscience
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    • 제37권7호
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    • pp.1213-1224
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    • 2024
  • Objective: Enterotypes (ETs) are the clustering of gut microbial community structures, which could serve as indicators of growth performance and carcass traits. However, ETs have been sparsely investigated in waterfowl. The objective of this study was to identify the ileal ETs and explore the correlation of the ETs with growth performance and carcass traits in Muscovy ducks. Methods: A total of 200 Muscovy ducks were randomly selected from a population of 5,000 ducks at 70-day old, weighed and slaughtered. The growth performance and carcass traits, including body weight, dressed weight and evidenced weight, dressed percentage, percentage of apparent yield, breast muscle weight, leg muscle weight, percentage of leg muscle and percentage of breast muscle, were determined. The contents of ileum were collected for the isolation of DNA and 16S rRNA gene sequencing. The ETs were identified based on the 16S rRNA gene sequencing data and the correlation of the ETs with growth performance and carcass traits was performed by Spearman correlation analysis. Results: Three ETs (ET1, ET2, and ET3) were observed in the ileal microbiota of Muscovy ducks with significant differences in number of features and α-diversity among these ETs (p<0.05). Streptococcus, Candida Arthritis, and Bacteroidetes were the presentative genus in ET1 to ET3, respectively. Correlation analysis revealed that Lactococcus and Bradyrhizobium were significantly correlated with percentage of eviscerated yield and leg muscle weight (p<0.05) while ETs were found to have a close association with percentage of eviscerated yield, leg muscle weight, and percentage of leg muscle in Muscovy ducks. However, the growth performance of ducks with different ETs did not show significant difference (p>0.05). Lactococcus were found to be significantly correlated with leg muscle weight, dressed weight, and percentage of eviscerated yield. Conclusion: Our findings revealed a substantial variation in carcass traits associated with ETs in Muscovy ducks. It is implied that ETs might have the potential to serve as a valuable biomarker for assessing duck carcass traits. It would provide novel insights into the interaction of gut microbiota with growth performance and carcass traits of ducks.

EU ETS 4기의 주요 제도 설계가 향후 국내 배출권거래제 운영에 미칠 영향 분석 (Analysis of the Impact of Key Design Elements for the EU-ETS Phase 4 on the K-ETS in the Future)

  • 손인성;김동구
    • 자원ㆍ환경경제연구
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    • 제30권1호
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    • pp.129-167
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    • 2021
  • 배출권거래제는 온실가스 감축과 저탄소 사회로의 전환을 위한 핵심 정책이다. EU 배출권거래제(EU ETS)는 운영기간, 핵심 설계 노하우 등에서 국내 배출권거래제보다 앞서 있는 좋은 벤치마크 대상이다. 이에 본 연구는 EU ETS 4기의 주요 제도 설계를 배출허용총량(Cap), 배출권 무상할당방식, 유·무상할당업종 선정 방식, 시장안정화 조치, 감축지원제도 등을 중심으로 살펴보았다. 그리고 EU ETS 1-4기의 주요 설계와 주요 설계 변경이 향후 국내 배출권거래제의 설계 및 운영에 미칠 영향을 각각 분석해보았다. 우선, 국내 배출권거래제 설계에 대한 영향으로는 벤치마크 갱신 방안 마련, 국내 산업구조 및 특성을 반영한 무상할당업종 선정 기준 마련과 2단계 평가 도입, 경매 수익의 구체적 활용방안 마련의 세 가지 요구가 증대될 것으로 예상된다. 다음으로 향후 배출권거래제 운영에 미칠 영향으로는 제도 개정의 객관적이고 심도있는 영향평가, 계획 및 제도 개정의 이른 확정을 통한 제도 안정성 및 대응 기회 제공, 배출권 거래제 거버넌스 조정 및 이해관계자 참여 확대 유도 세 가지를 들 수 있다.

The Study on EU ETS (欧盟航空减排交易体制评析) -From the Perspective of China-

  • Qin, Huaping
    • 항공우주정책ㆍ법학회지
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    • 제26권1호
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    • pp.127-145
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    • 2011
  • European Union unilaterally included the emissions from aviation activities into EU ETS on 19 November 2008 by amending Directive 2003/87/EC. According to the Directive all the emissions(mainly against the CO2) from aviation activities shall be subject to the regulation of EU ETS from 2012. For the period from 1 January 2012 to 31 December 2012, the total quantity of allowances to be allocated to aircraft operators shall be equivalent to 97% of the historical aviation emission s. From 1 January 2013, the allowances will be reduced to 95%. The allocation of allowances which may be applied by each operator with free of charge will be reduced from 85% to 82% from 1 January 2012 to 1 January 2013. Since the Directive will affect every country's airline industry more or less, the nations and international organizations respond variously. The controversial focus is that whether EU has the right to unilaterally include the emissions from international aviation activities into EU ETS. This article firstly analyzes the effect caused by EU ETS to China's airline industry, and then studies the legality of the action of EU subject to current positive international law, and finally draws the conclusion that EU enjoys no such right to unilaterally include the emissions from international aviation activities.

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실내사무환경에서의 환경성담배연기(ETS)중 일부 휘발성유기화합물(VOC)에 관한 연구 (A Study on Volatile Organic Compounds(VOC) in Environmental Tobacco Smoke(ETS) at Indoor Office Environments)

  • 하권철
    • 한국환경보건학회지
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    • 제27권3호
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    • pp.87-98
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    • 2001
  • There has been increased interest in the health effects of the Environmental Tobacco Smoke(ETS) as a confirmed human carcinogen. It has been known to be extremely difficult to make an accurate assessment of exposure to ETS since it is consisted of a variety of components and there are a number of labile chemicals. Therefore, it is necessary to obtain, to interpretate and to provide the data of quantitative exposure assessment to ETS in the field of environmental health. The purpose of this research is to evaluate the concentration of ETS using VOC in indoor office environments. The correlations and concentrations of benzene, RSP, 3-EP, nicotine that are indicators for ETS were investigate with smoking density, air change per hour(ventilation rate). Air samples were taken in smoking room(7 sites), smoking allowed office (3 sites), corridor outside smoking room(7 sites), non-smoking office (9 sites). The concentrations of benzene showed significant difference according to category of indoor office environments. The geometric mean concentration of benzene were 23.56 ${\mu}{\textrm}{m}$/㎥(range 4.80~192.90 ${\mu}{\textrm}{m}$/㎥) in smoking rooms. 6.16 ${\mu}{\textrm}{m}$/㎥ in smoking allowed offices, 1.32 ${\mu}{\textrm}{m}$/㎥ in the non-smoking offices respectively. The ratios of the concentration of benzene between outdoor air and smoking room, smoking allowed office, and non-smoking indicators concentrations, SD, and SI were 0.82(benzene and nicotine). 0.76(benzene and RSP), 0.60(benzene and SD), 0.76(benzene and SI). It is proposed that benzene is a good indicator for ETS.

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Computational modeling of cracking of concrete in strong discontinuity settings

  • Oliver, J.;Huespe, A.;Pulido, M.D.G.;Blanco, S.
    • Computers and Concrete
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    • 제1권1호
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    • pp.61-76
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    • 2004
  • The paper is devoted to present the Continuum Strong Discontinuity Approach (CSDA) and to examine its capabilities for modeling cracking of concrete. After introducing the main ingredients of the CSDA, an isotropic continuum damage model, which distinguishes tension and compression states, is used to implicitly induce a projected traction separation-law that rules the cracking phenomena. Criteria for onset and propagation of material failure and specific finite elements with embedded discontinuities are also briefly sketched. Finally, some representative numerical simulations of cracking, in plain and reinforced concrete specimens, using the CSDA are presented.

Characterization of Respirable Suspended Particles and Polycyclic Aromatic Hydrocarbons associated with Environmental Tobacco Smoke

  • Baek, Sung-Ok;Park, Jin-Soo;Kim, Mi-Hyun;Roger A, Jenkins
    • Journal of Korean Society for Atmospheric Environment
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    • 제16권E호
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    • pp.1-17
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    • 2000
  • In this study, the concentrations of particulate organic constituents of environmental tobacco smoke(ETS) were determined using an environmental smog chamber, where ETS is the sole source of target compounds. ETS was generated in a 30 ㎥ environmental chamber by a number of different cigarettes, including the Kentucky 1R4F reference cigarette and eight commercial brands. A total of 12 experimental runs was conducted, and target analytes included a group of ETS markers both in vapor and particulate phase and a class of polycylic aromatic hydrocarbos(PAHs) associated with ETS particles. The mass concentrations of PAH in ETS particles were also determined. The average contents of benzo(a) pyrene and benzo(a) anthracene in ETS particles for the commercial brands were 12.8 and 21.5$\mu\textrm{g}$/g, respectively, There values are all somewhat higher than those determined previously by other studies. Results form the chamber study are further used to estimate the average and variability of cigarette yields for target compounds associated with ETS. Finally, ratios of RSP to the surrogate standards of UVPM, FPM and solanesol were calculated for each sample. The average conversion factors factors for the eight commercial brands were 7.3, 38, and 41 for UVPM, EPM, and solanesol, respectively. The UVPM and FPM factors are in good agreement with the recently published values. Whereas there might be a substantial difference in the solanesol content among cigarettes produced in different countries, the variability is somewhat greater than those of UVPM and FPM, Unfortunately, comparison of the PAH yield data from this study with literature values was complicated by a lack of consistency in cigarette smoke generating methodology. Validation of the PAH yields was also difficult due to a lack of information on the ETS related PAH in the literature. From and engineering viewpoint , however, these data on the cigarette yields of ETS components may still provide useful information to studies on the mathematical modeling of indoor air quality management regarding tobacco smoke as a source of interest, or to studies on the assessment of human exposure to ETS.

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Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition

  • Xu, Lian;Fu, Mengxia;Chen, Dongrui;Han, Weiqing;Ostrowski, Michael C.;Grossfeld, Paul;Gao, Pingjin;Ye, Maoqing
    • BMB Reports
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    • 제52권10호
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    • pp.595-600
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    • 2019
  • Cardiac fibrosis is a common feature in chronic hypertension patients with advanced heart failure, and endothelial-to-mesenchymal transition (EndMT) is known to promote Angiotensin II (Ang II)-mediated cardiac fibrosis. Previous studies have suggested a potential role for the transcription factor, ETS-1, in Ang II-mediated cardiac remodeling, however the mechanism are not well defined. In this study, we found that mice with endothelial Ets-1 deletion showed reduced cardiac fibrosis and hypertrophy following Ang II infusion. The reduced cardiac fibrosis was accompanied by decreased expression of fibrotic matrix genes, reduced EndMT with decreased Snail, Slug, Twist, and ZEB1 expression, as well as reduced cardiac hypertrophy and expression of hypertrophy-associated genes was observed. In vitro studies using cultured H5V cells further confirmed that ETS-1 knockdown inhibited $TGF-{\beta}1$-induced EndMT. This study revealed that deletion of endothelial Ets-1 attenuated Ang II-induced cardiac fibrosis via inhibition of EndMT, indicating an important ETS-1 function in mediating EndMT. Inhibition of ETS-1 could be a potential therapeutic strategy for treatment of heart failure secondary to chronic hypertension.

The Relation between Exposure to Environmental Tobacco Smoke and the Quantity of Cotinine in the Urine of School Children in Taif City, Saudi Arabia

  • Desouky, Dalia El Sayed;Elnemr, Gamal;Alnawawy, Ali;Taha, Azza Ali
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권1호
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    • pp.139-145
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    • 2016
  • Environmental tobacco smoke (ETS) is a major public health problem for all ages. Despite the high prevalence of smoking among the Saudi population, there is limited information about levels of urinary cotinine in Saudi children exposed to SHS. The aim of the study was to assess the exposure of schoolchildren to ETS, and measure their urinary cotinine levels. Multistage cluster sampling was carried out, where schoolchildren from 4 schools were randomly chosen from primary schools in Taif city. A questionnaire including questions on SHS exposure and smoking rules in the residence were sent to students parents/guardians. Urine samples were taken and analyzed for total cotinine using chemiluminescent immunoassay. Of the studied children, 38.4% had a smoking father, 61.8%, 41.2% and 49.3% of them were exposed to ETS indoors, outdoors and both indoors and outdoors respectively. The mean urinary cotinine was significantly higher among children exposed to ETS compared to unexposed children. Urinary cotinine levels in children with both indoor and outdoor exposure was significantly higher compared with its level in children with single exposure. A significant positive correlation was found between urinary cotinine concentrations and the number of cigarette packs smoked by parents, and the number of smokers in the residence. The mean urinary cotinine level was significantly higher in children who reported no smoking rules at the residence.. The study revealed a high exposure of Saudi children to ETS. An antismoking media awareness campaign on the harmful effects of ETS should be carried out, in addition to family counseling programs targeted to parents to protect their children from ETS.

Forecasting with a combined model of ETS and ARIMA

  • Jiu Oh;Byeongchan Seong
    • Communications for Statistical Applications and Methods
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    • 제31권1호
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    • pp.143-154
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    • 2024
  • This paper considers a combined model of exponential smoothing (ETS) and autoregressive integrated moving average (ARIMA) models that are commonly used to forecast time series data. The combined model is constructed through an innovational state space model based on the level variable instead of the differenced variable, and the identifiability of the model is investigated. We consider the maximum likelihood estimation for the model parameters and suggest the model selection steps. The forecasting performance of the model is evaluated by two real time series data. We consider the three competing models; ETS, ARIMA and the trigonometric Box-Cox autoregressive and moving average trend seasonal (TBATS) models, and compare and evaluate their root mean squared errors and mean absolute percentage errors for accuracy. The results show that the combined model outperforms the competing models.