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Interaction Between Bronchiolitis Diagnosed Before 2 Years of Age and Socio-Economic Status for Bronchial Hyperreactivity

  • Leem, Jong-Han;Kim, Hwan-Cheol;Lee, Ji-Young;Sohn, Jong-Ryeul
    • Environmental Analysis Health and Toxicology
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    • 제26권
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    • pp.11.1-11.6
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    • 2011
  • Objects: The prevalence of asthma has increased in recent decades globally. The objective of the present study is to elucidate whether hospitalization for bronchiolitis in infancy and low socioeconomic status interact for bronchial hyperreactivity during teenage years. Method: We studied 522 children age 13-14 years attending schools in rural and urban areas to investigate the risk factors for bronchial hyperreactivity (BHR), defined as a provocation concentration of methacholine that causes a decrease of 20% ($PC_{20}$) in forced expiratory volume within 1 second. Clinical examination, skin prick test, spirometry, and methacholine challenge were performed on all study subjects, who provided written consent. We used multivariate logistic regression to investigate the risk factors for BHR, and analyze the interaction between hospitalization for bronchiolitis in infancy and low socioeconomic status. Results: Forty-six (10.3%) positive BHR cases were identified. In the multivariate logistic analysis, as independent predictors of BHR, adjusted odds ratio of bronchiolitis diagnosed before 2 years of age in low income families was 13.7 (95% confidence interval, 1.4 to 135.0), compared to reference group, controlling for age, gender, parental allergy history, skin prick test, and environmental tobacco smoke (ETS) exposure. Interaction was observed between bronchiolitis before 2 years old and low socioeconomic status on children's bronchial hyperreactivity (p-interaction=0.025). Conclusions: This study showed that bronchiolitis diagnosed before 2 years of age and low socioeconomic status interacted on children's bronchial hyperreactivity. Prevention of acute respiratory infection in early childhood in low socioeconomic status is important to prevent BHR as a precursor of asthma.

삼천포화력발전소 3, 4호기 증설에 따르는 정밀발파작업으로 인한 인접가동발전기 및 구조물에 미치는 진동영향조사 (On the vibration influence to the running power plant facilities when the foundation excavated of the cautious blasting works)

  • 허진
    • 기술사
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    • 제24권6호
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    • pp.97-105
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    • 1991
  • The cautious blasting works had been used with emulsion explosion electric M/S delay caps. Drill depth was from 3m to 6m with Crawler Drill ø70mm on the calcalious sand stone (soft-moderate-semi hard Rock). The total numbers of fire blast were 88 round. Scale distance were induces 15.52-60.32. It was applied to propagation Law in blasting vibration as follows. Propagation Law in Blasting Vibration (Equation omitted) where V : Peak partical velocity(cm/sec) D : Distance between explosion and recording sites(m) W : Maximum Charge per delay-period of eighit milliseconds o. more(kg) K : Ground transmission constant, empirically determind on the Rocks, Explosive and drilling pattern ets. b : Charge exponents n : Reduced exponents Where the quantity D / W$^n$ is known as the Scale distance. Above equation is worked by the U.S Bureau of Mines to determine peak particle velocity. The propagation Law can be catagrorized in three graups. Cubic root Scaling charge per delay Square root Scaling of charge per delay Site-specific Scaling of charge per delay Charge and reduction exponents carried out by multiple regressional analysis. It's divided into under loom and over 100m distance because the frequency is verified by the distance from blast site. Empirical equation of cautious blasting vibration is as follows. Over 30 ‥‥‥under 100m ‥‥‥V=41(D/$^3$√W)$\^$-1.41/ ‥‥‥A Over 100 ‥‥‥‥under 100m ‥‥‥V=121(D/$^3$√W)$\^$-1.56/ ‥‥‥B K value on the above equation has to be more specified for furthur understang about the effect of explosives, Rock strength. And Drilling pattern on the vibration levels, it is necessary to carry out more tests.

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교양댄스스포츠 참여 대학생의 스트레스해소 및 학업성적변화 탐색 (Exploration on Stress Solution and Change of their School Record according to Dance Sports Participation)

  • 김이정;송강영
    • 한국콘텐츠학회논문지
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    • 제13권1호
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    • pp.398-408
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    • 2013
  • 본 연구의 목적은 교양댄스스포츠 수업에 참여한 대학생들이 스트레스를 어떻게 해소하여 학업성적에 변화가 나타났는지를 알아보는데 있었다. 연구대상은 K지역에 위치한 교양댄스스포츠 수업에 참여한 대학생 8명이며, 자료 수집은 2012년 4월 19일부터 8월 20일까지, 심층면접과 참여관찰 등을 통해 이루어졌고, 면접 시간은 1-2시간 정도 실시하였다. 결론은 다음과 같다. 첫째, 수업수강 동기는 재미, 즐거움, 대중매체의 위력, 주변사람들의 권유 등으로 나타났다. 둘째, 댄스스포츠의 매력은 파트너와 함께 춤을 추고 움직임이 많아서 좋다고 하였다. 셋째, 대학생들의 스트레스 주요인은 취업, 원거리 통학, 등록금 걱정 등으로, 학업성적변화에 영향을 미친 요인은 자신감 향상, 생활습관의 변화, 체력향상, 스트레스 감소 등으로 나타났다. 추후연구에서는 특정 지역에 머물지 않고 다양한 지역의 대학생들을 대상으로 확대하고, 남녀 대학생들의 고민과 관심 영역이 다른 점을 감안하여 따로 분리해서 연구를 진행할 필요가 있을 것이다.

S 화력발전소 3, 4호기 증설에 따르는 정밀발파작업으로 인한 인접가동발전기 및 구조물에 미치는 진동영향조사 (On the vibration influence to the running power plant facilities when the foundation excavated of the cautious blasting works.)

  • 허진
    • 화약ㆍ발파
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    • 제9권4호
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    • pp.3-12
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    • 1991
  • The cautious blasting works had been used with emulsion explosion electric M /S delay caps. Drill depth was from 3m to 6m with Crawler Drill 70mm on the calcalious sand stone (soft-moderate-semi hard Rock) . The total numbers of feet blast were 88. Scale distance were induces 15.52-60.32. It was applied to Propagation Law in blasting vibration as follows .Propagtion Law in Blasting Vibration V=k(D/W/sup b/)/sup n/ where V : Peak partical velocity(cm/sec) D : Distance between explosion and recording sites(m) W ; Maximum Charge per delay -period of eight milliseconds or more(Kg) K : Ground transmission constant, empirically determind on the Rocks, Explosive and drilling pattern ets. b : Charge exponents n : Reduced exponents Where the quantity D/W/sup b/ is known as the Scale distance. Above equation is worked by the U.S Bureau of Mines to determine peak particle velocity. The propagation Law can be catagrorized in three groups. Cabic root Scaling charge per delay Square root Scaling of charge per delay Site-specific Scaling of charge delay Charge and reduction exponents carried out by multiple regressional analysis. It's divided into under loom and over loom distance because the frequency is varified by the distance from blast site. Empirical equation of cautious blasting vibration is as follows. Over 30m--under 100m----V=41(D/ W)/sup -1.41/-----A Over l00m---------V=121(D/ W)/sup -1.56/-----B K value on the above equation has to be more specified for furthur understand about the effect of explosives. Rock strength, And Drilling pattern on the vibration levels, it is necessary to carry out more tests.

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마우스 피부암 발생과정에 있어서 2,3,7,8-Tetrachlorodibenzo-p­Dioxin (TCDD) 처리에 의한 유전자발현 변화 연구 (Effects of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) on Gene Expression in Mouse Skin Carcinogenesis)

  • Ryeom Tai Kyung;Kim Ok Hee;Kong Mi Kyung;Park Mi Sun;Jee Seung Wan;Eom Mi Ok;Kang Ho Il
    • 한국환경성돌연변이발암원학회지
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    • 제25권1호
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    • pp.40-46
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    • 2005
  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) displays high toxicity in animals and has been implicated in human carcinogenesis. Although the mechanism of carcinogenesis by TCDD is unclear, it is considered to be a non-genotoxic compound and tumor promoter. In our experiment, we investigated the effects of TCDD on gene expression in mouse skin carcinogenesis. We used cDNA microarray to detect the differential gene expression in tumors induced in hairless mouse skin by MNNG plus TCDD protocol. We found that erb-2, c-ets2 and p27$^{kip1}$ were significantly up-regulated, but TNFR2, AKT-l, integrin $\beta$l, maspin, IGF-l, c-raf-l, Rb were significantly down-regulated, in tumor region, respectively. We also found that the expression of 53 genes involved in cen cycle, signal transduction, apoptosis, adhesion molecule, angiogenesis, and invasion, were changed two fold more, in tumor surrounding region. These data suggest that TCDD alters the expression of a large array of genes involved in apoptosis, cytokine production and angiogenesis in mouse skin carcinogenesis.

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A Case Study: Unsupervised Approach for Tourist Profile Analysis by K-means Clustering in Turkey

  • Yildirim, Mustafa Eren;Kaya, Murat;FurkanInce, Ibrahim
    • 인터넷정보학회논문지
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    • 제23권1호
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    • pp.11-17
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    • 2022
  • Data mining is the task of accessing useful information from a large capacity of data. It can also be referred to as searching for correlations that can provide clues about the future in large data warehouses by using computer algorithms. It has been used in the tourism field for marketing, analysis, and business improvement purposes. This study aims to analyze the tourist profile in Turkey through data mining methods. The reason relies behind the selection of Turkey is the fact that Turkey welcomes millions of tourist every year which can be a role model for other touristic countries. In this study, an anonymous and large-scale data set was used under the law on the protection of personal data. The dataset was taken from a leading tourism company that is still active in Turkey. By using the k-means clustering algorithm on this data, key parameters of profiles were obtained and people were clustered into groups according to their characteristics. According to the outcomes, distinguishing characteristics are gathered under three main titles. These are the age of the tourists, the frequency of their vacations and the period between the reservation and the vacation itself. The results obtained show that the frequency of tourist vacations, the time between bookings and vacations, and age are the most important and characteristic parameters for a tourist's profile. Finally, planning future investments, events and campaign packages can make tourism companies more competitive and improve quality of service. For both businesses and tourists, it is advantageous to prepare individual events and offers for the three major groups of tourists.

REC 명목가치 하락으로 인한 양적 통제장치로서의 RPS 왜곡 (REC Distortion as a Quantitative Control Policy due to REC Depreciation)

  • 유종민;이재석
    • 자원ㆍ환경경제연구
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    • 제31권1호
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    • pp.51-83
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    • 2022
  • 2012년부터 재생에너지 확대 정책을 위한 주요 정책 수단으로서 채택하고 있는 신재생에너지 공급의무화 제도(RPS)는 발전원별 경쟁을 유도함과 동시에 정부의 재정부담을 줄일 수 있다는 명백한 장점을 가지고 있지만, 높은 가중치 및 국가 공급인증서(REC) 남용 등으로 양적 통제정책으로서의 정책 왜곡을 초래하였다. 이는, REC 인플레이션과 그에 상응하는 MWh 단위의 실질 신재생에너지발전 실적 하락으로 이어졌고, 그 결과 RPS 기간 전체 신재생 의무이행량의 27.8%가 실제로는 충족되지 못했음을 본고에서 최초로 밝힌다. 뿐만 아니라 현재의 REC 가치왜곡은 인접제도라고 할 수 있는 RE100과 온실가스 배출권거래제와의 상호호환이 불가능해지게 하는 문제도 초래한다.

위성영상과 SEBAL 모형을 이용한 공간증발산량 산정 연구 (Estimation of Spatial Evapotranspiration Using satellite images and SEBAL Model)

  • 하림;신형진;이미선;김성준
    • 대한토목학회논문집
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    • 제30권3B호
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    • pp.233-242
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    • 2010
  • Bastiaanssen(1995)에 의해 개발된 SEBAL(Surface Energy Balance Algorithm for Land) 모형은 25개의 sub model들을 이용하여 지표의 증발산량과 기타 여러 에너지 교환을 계산하는 이미지-프로세싱 모형이다. SEBAL 모형은 Landsat 또는 기타 여러 위성영상을 통해 얻을 수 있는 열적외선 방사, 표시 및 근적외선 측정 자료 등을 사용한다. 본 연구에서는 한강유역의 주 지류인 경안천 유역에 모형을 적용시켰다. 증발산량(ET)은 4개년의(2001년-2004년) Landsat과 MODIS 위성영상을 입력자료로 사용하여, 에너지 균형원리를 통해 pixel-by-pixel을 기준으로 계산되었다. Landsat(30 m)과 MODIS(1 km) 사이의 비교 결과도 평가되었으며, Landsat과 MODIS 결과들은 FAO Penman-Monteith 증발산량과 비교하였다. 위성영상 ET들과 FAO Penman-Monteith ET 간의 절대 오차는 12% 이내로 확인되었으며, 유역 분포 증발산량의 시공간분포특성 또한 분석하였다.

Factors affecting the ongoing pregnancy rate in women with repeated implantation failure undergoing an endometrial receptivity array

  • Hyun Kyoung Lee;Kyoung Yong Moon;Haerin Paik;Byung Chul Jee
    • Clinical and Experimental Reproductive Medicine
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    • 제50권4호
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    • pp.277-284
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    • 2023
  • Objective: In this retrospective study, we analyzed factors influencing the ongoing pregnancy rate (PR) in women with repeated implantation failure (RIF) undergoing embryo transfer with endometrial receptivity array (ERA). Methods: Eighty-three consecutive personalized embryo transfers (pETs) with ERA, from 54 women with RIF, were selected from June 2020 to April 2022. Vitrified blastocyst transfer was timed based on ERA results. Results: The ongoing PR per pET was 33.7%. Using ERA, the endometrium was identified as pre-receptive in 26 cycles, early receptive in 25 cycles, receptive in 31 cycles, and late receptive in one cycle. With cycles categorized into three receptivity phases (pre-receptive, early receptive, or receptive), no significant differences were found in the clinical PR (27.3%, 55.6%, and 40%, respectively) or ongoing PR (9.1%, 55.6%, and 40%, respectively) after a single blastocyst transfer. Similarly, no significant differences were observed in the clinical PR or ongoing PR after the transfer of two or more blastocysts. Among women with ongoing pregnancy relative to those without, age at first pET was significantly lower (35 years vs. 39 years, p=0.001), while blastocyst score (23 vs. 18, p=0.012) and the proportion of blastocyst scores >18 (71.4% vs. 38.9%, p=0.005) were significantly higher. In multiple logistic regression analysis, the woman's age (odds ratio [OR], 0.814; 95% confidence interval [CI], 0.706 to 0.940; p=0.005) and blastocyst score >18 (OR, 3.052; 95% CI, 1.075 to 8.665; p=0.036) were identified as significant factors influencing ongoing pregnancy. Conclusion: In pET with ERA, ongoing pregnancy was closely associated with woman's age and blastocyst quality.

구주연합의 항공기 배출 규제 조치의 국제법적 고찰 (Legal Review on the Regulatory Measures of the European Union on Aircraft Emission)

  • 박원화
    • 항공우주정책ㆍ법학회지
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    • 제25권1호
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    • pp.3-26
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    • 2010
  • 환경 문제에 있어서 세계의 리더로서 앞 서 가는 구주연합(EU)은 2012년 1월 1일부터 EU 역.내외 항공기를 막론하고 EU 회원국 영토를 출발하고 도착하는 모든 항공기 운항자에 대하여 이들 항공기 엔진에서 배출되는 이산화탄소의 배출량을 규제하는 법 Directive 2008/101/EC를 2008년 제정, 공포하였다. 이에 따라 대한항공과 아시아나를 포함하여 EU를 운항하는 많은 EU 역외 항공사들은 지난 2004-2006년 3년간 연 평균 배출량의 97%만을 2012년 배출하고 2013년부터는 95%만을 배출 허용 받으며 부족한 배출량은 배출권 거래 시장에서 구입하여 충당하여야 한다. 상기 EU 조치는 다음과 같은 법적 문제를 야기한다. 첫째, EU의 법은 범 세계적 환경조약인 교토의정서가 선진국 그룹인 기후변화협약의 Annex I 국가에게만 이산화탄소 등 지구온난화가스 배출을 감축토록 한 것에 반한다. 교토의정서 제2조 2항은 지구온난화가스 감축에 있어서 항공기 배출에 관련한 체제를 ICAO를 통하여 해결하도록 위임하였는데 지역 기구인 EU가 이를 자체 지역에만 적용하기 위하여 작성한 것도 문제이다. 둘째, 역외 항공사들이 EU로 운항하는 데에 있어서 공해와 제3국의 상공을 비행하는데 EU 역내 비행에서 이루어지지 않는 여사한 비행 중 발생하는 배출을 어떤 근거로 EU가 규제할 수 있는가이다. 셋째, EU 회원국들이 Annex I 국가로서 교토의정서 상 항공기의 국내운항 배출에 대하여서는 2012년까지 이미 배출 감축의무를 지고 있음을 감안할 때, 2012년부터 시행되는 항공기 배출 감축 조치에 non-Annex I 국가의 항공 운항자를 끌어들이면서 EU 항공사들이 적어도 2012년에는 예상치 않은 이득을 얻는다는 문제도 발생한다. 과거 유사한 EU 주도의 환경관련 국제 분쟁을 살펴본 후, 상기 EU 조치를 국제법적으로 조명하고 결론에서 EU의 조치에 대한 국내적 대처를 간략기술하였다.

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