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A Study on the Ion Transfer System(WIT-I) for Improve on Side effect of Pharmacotherapy (약물치료의 부작용개선을 위한 이온도입 시스템(WIT-I)에 관한 연구)

  • Eo, Y.K.;Yang, K.M.;Chae, J.U.;Lee, I.S.;Lee, J.H.;Jeong, D.M.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.05
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    • pp.226-231
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    • 1996
  • Recently Iontophoresis is tried to physical therapy field.. It is method for direct penetrate to skin with ionization pharmacon because it is decreased side effect of pharmacon treatment such as gastrophathy and aphylaris of disease-causing germs. We designed WIT-I that is trial manufacture for clinical experiment This system is has been elrectrical paramete with 0-140V out range, 1-7mA current 1-15mim time set. Invite experiment, WIT-I kept designed performance which is a constant current in variable load resistance such as skin and electrode contact. It is estimated to have a practical use for physical therapy by iontophcresis.

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Influences of Phytoncide Supplementation on Growth Performance, Nutrient Digestibility, Blood Profiles, Diarrhea Scores and Fecal Microflora Shedding in Weaning Pigs

  • Zhang, S.;Jung, J.H.;Kim, H.S.;Kim, B.Y.;Kim, In-Ho
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.9
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    • pp.1309-1315
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    • 2012
  • A total of 140 weaning pigs ((Landrace${\times}$Yorkshire)${\times}$Duroc, BW = $6.47{\pm}0.86$ kg) were used in a 5-wk growth trail to determine the effects of phytoncide supplementation on growth performance, nutrient apparent total tract digestibility (ATTD), blood profiles, diarrhea scores and fecal microflora shedding. Pigs were assigned randomly by BW into 5 treatments, dietary treatments were: i) NC, basal diet; ii) PC, NC+0.05% tylosin; iii) EO, NC+0.1% essential oil; iv) PP, NC+0.2% PP (phytoncide with 2% citric acid), and v) PA, NC+0.2% PA (phytoncide). Each treatment had 7 replicate pens with 4 pigs per pen. All pigs were housed in pens with a self-feeder and nipple drinker to allow ad libitum access to feed and water throughout the experimental period. During 0 to 2 wks, supplementation with essential oil and PA decreased (p<0.05) G/F compared with the other treatments. During 2 to 5 wks, supplementation with PA led to a higher (p<0.05) G/F than the other treatments. At 2 wk, ATTD of dry matter (DM) and gross energy (GE) in EO treatment were decreased (p<0.05) compared with NC treatment. Dietary PC treatment improved (p<0.05) ATTD of DM and E compared with the CON group, and PA and PP treatments showed a higher (p<0.05) ATTD of E than that in NC treatment. Pigs fed phytoncide (PA and PP) had a greater (p<0.05) ATTD of DM than those of NC and EO treatments at 5 wk. Moreover, supplementation with phytoncide elevated (p<0.05) the concentration of immunoglobulin (IgG) in blood at 2 wk. The inclusion of EO, PP and PA treatments showed a greater (p<0.05) amount of fecal Lactobacillus compared with CON group. However, no difference (p>0.05) was observed in diarrhea scores among treatments. In conclusion, phytoncide can elevate feed efficiency, nutrient digestibility, and improve the fecal Lactobacillus counts in weaning pigs. Our results indicated that the phytoncide could be used as a good antibiotics alternative in weaning pigs.

Insulation Coordination of Forced Drainage in Electric Railway (직류방식 전기철도에서 강제배류기의 절연협조)

  • Min, B.H.;Eo, I.S.
    • Proceedings of the KIEE Conference
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    • 1999.07a
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    • pp.446-448
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    • 1999
  • The forced drainage set up to decrease the cathodic protection in each kind of steel conduit laid under the ground is so proscribed to be maintained less than 60V in its output voltage that insulation coordination is easy to be left out of account, on the basis of 60V of working voltage. When railway or subway break down during the service of a subway, 1,500 voltage approximating to line voltage flows through the load terminal of the drainage (rail and underground conduit) though momentary in the worst case. And so, an accident followed by dielectric breakdown, fire and damage by a fire is expected. Therefore, I suggest that insulation coordination should be considered against such a thing on designing, producing and setting up forced drainage.

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The Characteristics of Quality and Storage of Tofu(Soybean Curd) according to the Concentration of Cuttlefish Ink (오징어 먹물 첨가량에 따른 두부의 품질 특성 및 저장성)

  • Park, Eo-Jin;Park, Geum-Soon
    • Journal of the East Asian Society of Dietary Life
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    • v.16 no.6
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    • pp.707-716
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    • 2006
  • To make tofu (soybean curd) with cuttlefish int the cuttlefish ink diluted 20-fold was added to soymilk in the ratio of 0%, 1%, 3%, 5%, 7% and 9% there is no respective comparison here respectively and the prepared cuttlefish inky tofu samples were stored for 15 days at $4^{\circ}C$. After storage, the tofu samples were tested for yield, pH, acidity, bacterial growth, sensory evaluations and physical properties. The yields of 7%(I7) and especially 9%(I9) cuttlefish ink tofu were higher than that of the control tofu(I0). The pH was decreased, but the acidity was increased with increasing storage period. The microorganism count of I9 was the lowest during the storage period. The turbidity gradually increased until 9 days of storage and rapidly increased at 12 days of storage. In the measurement of inky tofu color, the L and b values were decreased during the storage period. In the texture analysis, the hardness, gumminess and brittleness of inky tofu were increased until 12 days of storage but then decreased. Chewiness was decreased with increasing storage period. Springiness of Il and I3 was higher than that of I0. In sensory evaluation, color was increased with increasing cuttlefish inky concentration. Sleekness of I3 was the highest. Hardness and chewiness of inky Il and I3 were the highest. Springiness, cohesiveness and softness were the highest in I3. In overall acceptability, I3 gained the highest score.

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The Effects of Syllable Boundary Ambiguity on Spoken Word Recognition in Korean Continuous Speech

  • Kang, Jinwon;Kim, Sunmi;Nam, Kichun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.6 no.11
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    • pp.2800-2812
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    • 2012
  • The purpose of this study was to examine the syllable-word boundary misalignment cost on word segmentation in Korean continuous speech. Previous studies have demonstrated the important role of syllabification in speech segmentation. The current study investigated whether the resyllabification process affects word recognition in Korean continuous speech. In Experiment I, under the misalignment condition, participants were presented with stimuli in which a word-final consonant became the onset of the next syllable. (e.g., /k/ in belsak ingan becomes the onset of the first syllable of ingan 'human'). In the alignment condition, they heard stimuli in which a word-final vowel was also the final segment of the syllable (e.g., /eo/ in heulmeo ingan is the end of both the syllable and word). The results showed that word recognition was faster and more accurate in the alignment condition. Experiment II aimed to confirm that the results of Experiment I were attributable to the resyllabification process, by comparing only the target words from each condition. The results of Experiment II supported the findings of Experiment I. Therefore, based on the current study, we confirmed that Korean, a syllable-timed language, has a misalignment cost of resyllabification.

The Effect of Five Different Trunk Stabilization Exercise on Thickness of Abdominal Muscle Using an Ultrasonography Imaging in Normal People (정상인에서 5가지 체간 안정화 운동자세가 초음파 영상을 이용한 복부근 두께에 미치는 영향)

  • Kang, Jung-Hyun;Shim, Jae-Hun;Chon, Seung-Chul
    • Physical Therapy Korea
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    • v.19 no.3
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    • pp.1-10
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    • 2012
  • The aim of this study is to compare measurements of abdominal muscle thickness using ultrasonography imaging (USI) to those using a special transducer head device, during five different trunk stabilization exercises, ultimately to determine which exercise led to the greatest muscle thickness. Thirty eight healthy subjects participated in this cross-sectional study. The five types of trunk stabilization - i.e., a sit-up on the supine, an upper and lower extremity raise with quadruped on the prone, a leg raise in sitting on the ball, trunk rolling on the ball, and balance using sling on the prone position - were each performed with an abdominal draw. The thickness of the abdominal muscle - including the transverse abdominal (TrA), internal oblique (IO), and external oblique (EO) - was measured by USI with a special transducer head device, at rest and then at contraction in each position. Data were analyzed using one-way repeated ANOVA with the level of significance set at ${\alpha}$=.05. The results were as follows: 1) the TrA thickness was statistically significant (p<.05), whereas the IO and EO thicknesses were not (p>.05); 2) among the five types of trunk stabilization, TrA thickness significantly increased with the balance using a sling in the prone position, (p<.05), whereas no significant difference was noted for the four types of trunk stabilization (p>.05); 3) reliability data showed that there was a high degree of consistency among the measurements taken using the special transducer head device (ICC=.92). In conclusion, the balance using a sling in the prone position was more effective than any of the four other types of trunk stabilization in increasing TrA thickness in healthy subjects.

Permeation Characteristics of Water Vapor Through PVA/PSSA_MA/THS-PSA Membranes (PVA/PSSA-MA/THS-PSA 막의 수증기 투과특성에 관한 연구)

  • Rhim, Ji-Won;Cho, Hyun-Il;Kim, Dae-Hoon;Ha, Seong-Yong;Nam, Sang-Yong
    • Membrane Journal
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    • v.17 no.2
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    • pp.140-145
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    • 2007
  • In this study, 3-(trihydroxysilyl)-1-propanesulfonic acid (THS-PSA) was added to poly(vinyl alcohol) (PVA) membranes crosslinked with poly(styrene sulfonic acid-co-maleic acid) (PSSA_MA) to improve the separation characteristics toward water vapors in the air. The prepared membranes varying both PSSA_MA and THS-PSA amounts were also synthesized at different cross linking temperatures. Then, in order to investigate the separation characteristics of the resulting membranes, the dynamic vapor sorption (DVS) and vapor permeation experiments were carried out. The increase of cross-linking temperature showed longer time to reach the equilibrium sorption state from the dynamic vapor sorption experiments. PVA/PSSA_MA (3%)/THA-PSA(7%) prepared at $120^{\circ}C$ gave the highest permeability of 480 barrer at $35^{\circ}C$.

The essay of Bijeung by chinese doctors in 20th century - Study of - (20세기(世紀) 중의사(中醫師)들의 비증(痺證)에 대(對)한 논술(論述) 연구(硏究) - 《비증전집(痺證專輯)》 에 대(對)한 연구(硏究) I -)

  • Kim, Myung Wook;Oh, Min Suk
    • Journal of Haehwa Medicine
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    • v.9 no.1
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    • pp.547-594
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    • 2000
  • I. Introduction The essence of Oriental medicine consists of ancient books, experienced doctors and succeeded skills of common society. Many famous doctors studied medical science by their fathers or teachers. So the history of medical science is long. $\ll$DangDaeMyeongIImJeungJeongHwa(當代名醫臨證精華)$\gg$ written by SaWoogWang(史宇廣) and DanSeoGeon(單書健) has many medical experience of famous doctors. So it has important historical value. Bi(痺) means blocking. BiJeung is one kind of symptoms making muscles, bones and jonts feel pain, numbness or edema. For example it can be gout or SLE etc. So I studied ${\ll}BiJeungJuJip{\gg}$. II. Final Decision Following decisions of Chinese doctors of 20th century are as follows ; 1. JuYangChun(朱良春) emphasized on IkSinJangDok(益腎壯督) to treat BiJeong. And he devided WanBi(頑痺) as PungHanSeup(風寒濕), DamEo(痰瘀), YeolDok(熱毒), SinHeo(腎虛). He used insects for medicine. 2. ChoSuDoek(焦樹德) introduced past prescription. He used ChiBiTang(治痺湯) to treat HaengBi(行痺), TongBi(痛痺), ChakBi(着痺). He insisted that Han(寒; coldness) and Seup(濕; dampness) be Eum(陰) and Pung(風; wind) can change his character to be Eum. After all BiJeung is usually EumJeung. So he used GaeJi(桂枝) and BuJa(附子). By the way he used ChungYeolSanBiTang(淸熱散痺湯) for YeolBi, BoSinGeoHanChiWangTang SaBok(王士福) emphasized on the importance of medicine. He introduced many treatments like CheongYeol(情熱) for YeolBi and YiO(二烏) for HanBi. And he divided BiJeung period for three steps. At 1st step, we must use GeoSa(祛邪), at 2nd step, we must use BuJeong(扶正) and at 3rd step, we must use BoHyeol(補血), he insisted. And he introduced many herbs to treat BiJeung. 4. JeongGwangJeok(丁光迪) said that GaeJi(桂枝), MaHwang(麻黃), OYak(烏蘖) and BuJa(附子) are very important for TongRak(通絡). And pain usually results from Han(寒), so he liked to use hot-character herbs. 5. MaGi(馬志) insisted that BiJeung usually result from ChilJeong(七情). And he liked to use insects for treatment of BiJeung. 6. WeolSeokMu(越錫武) introduced 8 kinds of treatments and divided BiJeung period. Also he divided BeJeung for PungBi(風痺), HanBi(寒痺) and SeupBi(濕痺). 7. SeoGeaHam(徐季含) observed many patients and concluded that 86.7% of BiJeung is HeuJeung(虛症). 8. YuJiMyeong(劉志明) said that YeolBi is important and CheongYeol is also important. So he emphasized on DangGyuiJeomTongTang(當歸拈痛湯) and SeonBiTang(宣痺湯). 9. WangLiChu(汪履秋) studied cause of WanBi. Internal cause is GiHyeolHeo(氣血虛) and GanSinHeo(肝腎虛) and external cause is SaGi(邪氣) he insisted. 10. WangSaSang(王士相) said that YeolBi can be SeupYeolBi or EumHeuYeolBi(陰虛熱痺) and HanSeupBi(寒濕痺) is rare. He use WooBangJaSan(牛蒡子散) and BangPungHwan(防風丸) for SeupYeolBi, DangGyuiSaYeokTang(當歸四逆湯) for HanSeupBi. 11. JinTaekGang(陳澤江) treated YeolBi with BaekHoGaGyeJiTang(自虎加桂枝湯) and SaMyoSan(四妙散). If they don't have effect, he tried to cure BiJeung step by step. And he used e term of GeunBi(筋痺) and BangGiMogwaEIInTang(防己木瓜薏苡仁湯) was good for GeunBi. 12. MaSeoJeong(麻瑞亭) said that PungSeupYeokJeul(風濕歷節) is BiJeung and it is related to GanBinSin(肝脾腎; liver, Spleen, Kindey). And he emphasized on balance WiGi(衛氣) and YoungHeul(營血). 13. SaJeJu(史濟桂) said that GeunGolBi(筋骨痺) is similar to arthritis and sometimes called ChakBi. And SinBi(腎痺) is terminal stage of ChakBi, he said. He also used insects for treatment. 14. JeongJeNam(丁濟南) tried to cure SLE and used GyeJi, CheonCho(川椒), SinGeunCho(伸筋草), SunRyeongBi(仙靈脾), HyconSam(玄蔘) and GamCho(甘草). 15. JinGYungHwa(陳景和) emphasized on diagnosis of tongue. If the color of tongue is blue, it usually has EoHyeol(瘀血), for example. And he also used insects. 16. JuSongI(朱松毅) tried to devide YeolBi with OnByeong(溫病), Wi(衛), Gi(氣) and Hyeol(血). 17. RuDaBong(蔞多峰) said that JyeongHeo(正虛), OiSa(外邪) and EoHyeol are closely related. And he explained BiJeung by deviding the body into the part, for example head, neck, shoulder, waist, upper limb and lower limb. 18. YuMuBo(劉茂甫) defined PungHanSyubBi as chronic stage and YeolBi as acute stage.

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Resveratrol Inhibits Nitric Oxide-Induced Apoptosis via the NF-Kappa B Pathway in Rabbit Articular Chondrocytes

  • Eo, Seong-Hui;Cho, Hongsik;Kim, Song-Ja
    • Biomolecules & Therapeutics
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    • v.21 no.5
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    • pp.364-370
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    • 2013
  • Resveratrol (trans-3,4'-trihydroxystillbene), a naturally occurring polyphenolic antioxidant found in grapes and red wine, elicits diverse biochemical responses and demonstrates anti-aging, anti-inflammatory, and anti-proliferative effects in several cell types. Previously, resveratrol was shown to regulate differentiation and inflammation in rabbit articular chondrocytes, while the direct production of nitric oxide (NO) in these cells by treatment with the NO donor sodium nitroprusside (SNP) led to apoptosis. In this study, the effect of resveratrol on NO-induced apoptosis in rabbit articular chondrocytes was investigated. Resveratrol dramatically reduced NO-induced apoptosis in chondrocytes, as determined by phase-contrast microscopy, the MTT assay, FACS analysis, and DAPI staining. Treatment with resveratrol inhibited the SNP-induced expression of p53 and p21 and reduced the expression of procaspase-3 in chondrocytes, as detected by western blot analysis. SNP-induced degradation of I-kappa B alpha ($I{\kappa}B-{\alpha}$) was rescued by resveratrol treatment, and the SN50 peptide-mediated inhibition of NF-kappa B (NF-${\kappa}B$) activity potently blocked SNP-induced caspase-3 activation and apoptosis. Our results suggest that resveratrol inhibits NO-induced apoptosis through the NF-${\kappa}B$ pathway in articular chondrocytes.

Clinical research methodology for Traditional Korean Medicine treatment of lung cancer : Evidence-based approach (폐암(肺癌)의 한방치료 임상연구 방법론)

  • Kim, Kyung-Suk;Kim, Sme-Hyun;Eo, Wan-Kyu;Cheon, Seong-Ha;Eom, Seok-Ki;Jo, Hak-Jun
    • Journal of Korean Medical classics
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    • v.23 no.4
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    • pp.39-62
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    • 2010
  • Background : I investigated clinical research methodology of Traditional Korean Medicine(TKM) for treatment of lung cancer with Evidence Based Medicine(EBM) approach. Methods : I conducted the internet search of National Central Library, the National Assembly Library, Korea Education & Research Information Service, Korea Institute of Science and Technology Information for Korean theses and papers, and MEDLINE for the outside articles. Conclusion : In addition to outcomes of clinical trial, abundant clinician's experience and patients' preference are also considered. Pragmatic trials and quasi-experimental trials are better than clinical trials to plan clinical design of TKM for lung cancer and appropriate endpoints includes overall survival, disease-free survival, patient reporting outcome.