• Animal Bioscience
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• 제34권1호
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• pp.154-160
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• 2021

Objective: The effect of environmental enrichment on the behaviour of piglets in the nursery phase was evaluated. Methods: A total of 450 hybrid pigs (21 day old), including both females and uncastrated males, weighing approximately 6 kg, were distributed in a completely randomised design with 3 treatments and 3 replicates of 50 animals each. The treatments were: i) pen without environmental enrichment (control), ii) treatment consisting of continuous environmental enrichment (CEE) with rubber balls throughout the experimental period, and iii) treatment consisting of environmental enrichment with washed balls (EEWB) during the whole experimental period which were removed daily for washing. For the behavioural evaluation, 10 animals were randomly selected per replicate. The behavioural assessments were performed once a week, from 8 am to 6 pm, using images captured with a video camera. The data were submitted to non-parametric analyses, the means were compared using the Bonferroni test, and Person's correlations were also calculated. Results: A statistical difference (p = 0.001) was observed in the B5 (playful) behaviour; the animals in the EEWB treatment group had a higher frequency of this behaviour than animals in the control treatment group. The animals in the control group showed a higher frequency of B7 behaviour (lying down) (p = 0.026) than those in the EEWB and CEE treatment groups. The animals in the control group had a higher frequency of the B9 (belly nosing) behaviour than those in the EEWB group (p = 0.015). There was a tendency towards a higher frequency of behaviour B3 (walking in the pen) (p = 0.067) when the animals received the control treatment than treatments EEWB or CEE. Conclusion: The use of an enriching object improved the animal welfare and altered the correlation between the evaluated behaviours compared to the animals that did not have environmental enrichment.

• 한국산업보건학회지
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• 제26권2호
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• pp.178-187
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• 2016

Objectives: Diisocyanates are a potent inducer of diseases of the airways, especially asthma. In this study, toluenediamine(TDA) and methylenedianiline(MDA) in urine were evaluated as biomarkers of exposure to tolunenediisocyanate(TDI) and methylenediphenyl diisocyanate(MDI), respectively. Methods: Workers exposed to TDI and MDI, as well as non-occupationally exposed subjects, were studied and pre- and post-shift urine samples were collected from 8 control subjects and 8 workers from a factory which manufactures polyurethane products for reducing noise and vibration in automobiles. Airborne TDI and MDI(n=8) were sampled on solvent-free glass filters impregnated with n-butylamine and detected by liquid chromatography atmospheric pressure ionization tandem mass spectrometry. Urinary TDA and MDA were detected as pentafluoropropionic acid anhydride(PFPA) derivatives by liquid chromatography electrospray ionization tandem mass spectrometry. Results: The median levels of urinary 2,6-TDA(p<0.001), 2,4-TDA(p=0.001), and MDA(p<0.001) of workers in post-shift samples were significantly higher than those of controls. The median levels of urinary 2,6-0TDA($0.63{\mu}g/g$ creatinine vs $0.34{\mu}g/g$ creatinine, p=0.017) and MDA($4.21{\mu}g/g$ creatinine vs $3.18{\mu}g/g$ creatinine, p=0.017) of workers in post-shift samples were significantly higher than those of the pre-shift samples. There were significant correlations between the urinary 2,6-TDA, 2,4-TDA, and MDA of workers in post-shift samples and the airborne 2,6-TDI(rho=0.952, p<0.001), 2,4-TDI(rho=0.833, p=0.001), and MDI(rho=0.952, p<0.001). Conclusions: These urinary diamines, metabolites of diisocyanates, in post-shift samples were useful biomarkers to assess occupational exposure to diisocyanates.

• 과학기술학연구
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• 제2권2호
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• pp.145-189
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• 2002

이 글은 인구고령화에 대응하는 복지 과학기술의 잠재적 기여와 역할을 고찰한 시론이다. 이 글에서 복지 과학기술은 복지 중진을 위해 적용되거나 체화된 지식의 체계를 가리키되 신체기능의 저하나 손상에 대한 예방, 보조, 지원을 통해 삶의 질을 향상하는 기술을 의미하고, 단순히 손상되거나 저하된 신체기능의 보상과 대체만이 아니라 사회적 기술적 환경과 지원 시스템의 확충을 포함하는 개념이다. 복지 과학기술은 종래 장애인이나 노인 등 특정 집단의 사람들을 위한 제품이나 서비스에 초점을 맞추었으나 연령이나 장애에 관계없이 모든 사람이 사용할 수 있는 보편적 디자인제품이나 서비스를 강조하는 방향으로 중요한 변화가 일고 있다. 이러한 복지과학기술의 개념 변화는 복지 과학기술이 일차적으로 노인복지를 증진하는 잠재력을 주목할 뿐만 아니라 우리 사회의 삶의 질을 전반적으로 높이는 가능성을 직시하고 나아가서 사회경제적 활력을 증진하는 데 기여할 가능성을 포착할 수 있도록 한다. 인구고령화에 대응하는 복지 과학기술 또는 제론테크놀로지(GT)는 '개인적 지체'만이 아니라 '구조적 지체'에도 대응해야 한다는 것이 본고의 중요한 주장 가운데 하나이다. 이것은 노인들을 단지 사회적 보호나 개호의 대상자 집단으로 객체화하는 것이 아니라 나이가 들어서도 독립적으로 살아가고자 하는 주체적 존재이며 정상적 시민으로 바라보는 관점의 전환을 함축한다.

• 한국산업보건학회지
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• 제31권3호
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• pp.286-293
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• 2021

Objectives: Inorganic dust is known to be a risk factor for chronic obstructive pulmonary disease (COPD) regardless of smoking and pneumoconiosis. Adaptive and innate immunity, including lymphocyte infiltrate, are involved in the pathogenesis of COPD. The purpose of this study was to analyze the lymphocyte subsets in the blood of workers exposed to inorganic dust and confirm the influencing factors. Methods: The general characteristics of the subjects (n=107) were analyzed through a personal questionnaire. Diagnosis of COPD was established according to pulmonary function tests with FEV₁/FVC post bronchodilator lower than 70%, according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. For lymphocyte analysis, blood was stained with a fluorescent CD marker and analyzed by flow cytometry. Results: The increase in CD4⁺ T lymphocytes was associated with a decrease in age (𝛽=-0.273, p=0.008) and an increase in the cumulative smoking amount (𝛽=0.205, p=0.034). The increase in NK cells was associated with an increase in age (𝛽=0.325, p=0.001) and a decrease in cumulative smoking (𝛽=-0.220, p=0.019). The period of exposure to dust, %FVC predicted and %FEV₁/FVC, and the relative population of peripheral blood lymphocytes did not show a statistically significant relationship. Conclusions: CD4⁺ T lymphocytes and CD56⁺CD16⁺ NK cells in peripheral blood were more related to age and cumulative smoking than the duration of dust exposure. Age and smoking are major risk factors for the development of COPD, so it can be predicted that peripheral blood CD4⁺ T lymphocytes and CD56⁺CD16⁺ NK cells are related to the development of COPD in workers exposed to inorganic dust.

• 한국산업보건학회지
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• 제29권1호
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• pp.42-49
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• 2019

Objective: Chronic obstructive pulmonary disease(COPD) is characterized by persistent airflow limitations associated with chronic inflammatory response due to noxious particles or gases in the lung. Iron deficiency is associated with chronic inflammation, such as COPD. The aim of this study was to evaluate the relationship among iron deficiency, iron homeostasis, and inflammation in retired miners with COPD. Methods: The serum levels of ferritin, soluble transferrin receptor(sTfR), and transferrin saturation(TSat) as biomarkers for iron deficiency and high-sensitivity C-reactive protein(hsCRP) as a biomarker for inflammation and hepcidin as a biomarker for iron homeostasis were measured in 93 male subjects. Iron deficiency was defined as any one or more of (1) sTfR>28.1 nmol/L, (2) TSat<16%, and (3) ferritin< $12{\mu}g/L$. Results: Iron deficiency was found 28% of the study subjects. Median levels of serum hsCRP was significantly increased related to airflow limitation of COPD(GOLD 1, $0.09{\mu}g/dL$ vs. GOLD 2, $0.17{\mu}g/dL$ vs. GOLD $3{\leq}$, $0.30{\mu}g/dL$, p=0.010), and was positively correlated with hepcidin(p=0.009). Mean level of serum hepcidin was lower in COPD subjects with iron deficiency(p=0.004) and serum levels of hepcidin was negatively correlated with %$FEV_1$ predicted(p=0.030). Conclusions: These results suggest that high serum levels of hepcidin are related to severe airflow limitation or inflammation and can decrease iron availability, regardless of iron status.

• 한국가금학회지
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• 제48권4호
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• pp.239-253
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• 2021

본 연구는 Cobb종 및 Ross 308종 육계가 동물복지 사육환경에 따라 나타내는 대사체학적 변화를 연구하기 위하여 수행되었다. 일반농장과 동물복지농장(사육면적, 사육밀도, 암모니아 농도, 볏짚 등 제공)에 1일령의 Cobb종 및 Ross종 육계를 35일간 사육하고, 도계 후 가슴육과 다리육을 채취하여 분석에 이용하였다. 대사체 분석은 one-dimensional ¹H 핵자기공명분광법을 이용하였고, 직교부분최소자승판별분석(OPLS-DA)과 대사경로 분석을 함께 수행하였다. OPLS-DA 결과 육계 가슴육은 Ross종에 한하여 사육농장간 뚜렷한 구분이 가능하였다. 동물복지농장 유래 Ross종 육계 가슴육은 acetate, anserine, creatine, inosine monophosphate 함량이 일반농장 닭가슴육에 비해 유의적으로 높았다(P<0.05). 반면 육계 다리육은 OPLS-DA 결과 Cobb종 육계에서만 사육농장에 따른 구분이 뚜렷하게 나타났는데, glucose와 lactate를 포함한 5종의 대사체 함량은 동물복지농장에서 사육된 경우에 높았으나 7종의 유리아미노산을 포함한 9종의 대사체 함량은 낮았다(P<0.05). 대사경로 분석 결과 Ross종 육계 가슴육에서는 4종, Cobb종 육계 다리육에서는 glycolysis/gluconeogenesis를 포함한 20종의 대사경로에서 사육농장 간 유의적인 차이(P<0.05)가 나타났다. 동물복지농장에서 사육된 Ross종 육계 가슴육과 Cobb종 육계 다리육은 일반농장에서 사육된 경우와는 다른 대사체학적 특성을 나타냈으며, 특히 풍미 물질에의 뚜렷한 차이를 보여 관능적 특성에 영향을 미칠 수 있으리라 사료된다.

• 한국조경학회지
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• 제42권4호
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• pp.21-29
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• 2014

소득수준 향상으로 삶의 질이 중시되는 시대로 접어들면서 건강과 여가에 대한 사회적 관심이 증대되고 있다. 본 연구는 도시환경과 도시민의 여가의 관계에 주목하여 공원, 하천과 같은 도시 오픈스페이스가 거주민, 특히 고령화 사회의 사회적 관심사인 노인 거주민의 옥외 여가활동에 미치는 영향을 실증분석하였다. 여가소비에 영향을 미치는 수요와 공급요인 중에서 선행연구는 주로 수요측면의 개인 특성에 초점을 맞춘 반면, 본 연구는 공급측면의 환경적 지역적 특성을 함께 고찰하는 특성을 지닌다. 분석자료는 개인의 거주지역 정보가 행정동의 근린수준까지 세분화되어 있는 2010년 국민여가활동조사자료를 활용하였으며, 개인 및 지역특성을 동시에 고려하기 위하여 다중회귀분석과 함께 위계선형분석을 수행하였다. 두 모형에서 일관되게 발견되는 연구의 주요결과는 다음과 같다. 첫째, 도시 오픈스페이스 공급은 거주민의 옥외 여가활동 증진에 유의미한 영향을 미친다. 둘째, 이러한 오픈스페이스 공급효과는 노인계층에서 더욱 크게 나타난다. 셋째, 도시 오픈스페이스가 제공하는 옥외 여가활동은 상대적으로 소득수준, 교육수준이 낮은 사회경제적 취약계층에게 더욱 유용하다. 종합하면 도시 오픈스페이스가 옥외 여가공간으로서의 기능뿐만 아니라 노인시설, 공공보건시설, 사회복지시설로서의 기능을 복합적으로 발휘할 수 있음을 의미한다. 이러한 점에서 도시오픈스페이스는 도시계획시설의 관점에서 고령화사회에 대응하고 건강도시와 복지사회를 구현하기 위한 지방공공재 공급계획의 일환으로 확장될 필요가 있다.

• 한국전문물리치료학회지
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• 제16권4호
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• pp.44-52
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• 2009

It is known that individual factors as cognitive, perception, emotion, and motivation may greatly influence on recovery from neurologic region. This study was to investigate the effects of environmental reinforcement through motivation to perform the tasks voluntarily on motor and cognition function in rats with focal ischemic brain injury. Focal ischemic brain injury was induced in Sprague-Dawley rats (15 rats, $250{\pm}50$ g) through middle cerebral artery occlusion (MCAo). And then, experiment groups were randomly divided into three groups; The control group: MCAo induction ($n_1$=5), the environmental reinforcement (ER) group: the application for ER after MCAo induction ($n_2$=5), the environmental reinforcement through motivation (ERM) group: the application for ERM after MCAo induction ($n_3$=5). The climbing test (CT) and the modified limb placing tests (MLPTs) to measure the motor function and the Morris water maze acquisition test (MWMAT) and the Morris water maze retention test (MWMRT) to measure the cognitive function were performed. For the CT, the ERM group was significantly larger than the ER group. For the MLPTs, the ERM group was significantly decreased compared to other groups. For the MWMAT, the time to find the circular platform in the ERM group significantly decreased compared to other groups. For the MWMRT, the time to dwell on the quadrant circular platform in the ERM group was significantly increased compared to other groups. These results suggested that the ERM could improve the motor and cognitive functions in the rats with focal ischemic brain injury.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제13권1호
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• pp.27-35
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• 2007

According to the 2005 Korean census, the 65 and over population now exceeds 9.5% of the total population and is growing rapidly. Meeting elderly environment and care needs of this rapidly growing segment of the population becomes a major challenge for public policies and planners. Since great deal amount of elderly will reside in their houses, aging in place concept becomes important. For the success of aging in place, the quality of individual house unit, community support systems, and quality of senior center of the community are crucial. Since elderly environments and facilities serve not only medical and/or care programs but also social activity program in aging society, senior centers need to promote social activities and other care programs. The purpose of this study is to analyze characteristics of environmental affordance of a well received senior center in Tokyo, Japan. In order to analyze the characteristics, Murtha & Lee user benefit criteria and Lawton's environmental affordance approaches were used. As results, design characteristics and interior elements which provide environmental affordance were enumerated by type of space. Based on needs and user benefit criteria, those features were analyzed. This study shows design characteristics, elements, and attributes which are well received and utilized by elderly users.

• 한국대기환경학회지
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• 제30권5호
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• pp.449-460
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• 2014

Since the emergence of domestically produced automobiles in 1964, the number of automobiles in circulation in South Korea has increased constantly. With this rapidly increasing number of automobiles, automobile-induced environmental pollution has become an issue of great concern, especially with regard to air pollution. Of the carbon composites contained in automobile exhaust gas, PAHs are known to be carcinogenic and highly deleterious to humans and thus need to be urgently mitigated. To address this issue of PAHs, this study was conducted to estimate qualitative of particulate PAHs contained in carbon composites in automobile exhaust gas, by capturing all particulate matter discharged from the latter. To allow for differentiated analyses, the automobiles investigated were divided into 4 groups: gasoline vehicle, motocycle, diesel vehicle, and LPG vehicle. Samples were analyzed using two methods. First, in-depth analysis was performed on organic carbon (OC) and elemental carbon (EC) composites with analysis parameters, using the Thermal Optical Transmittance Method (NIOSH 5040). Second, for the examination of particulate PAHs, GC/MSD was used to analyze the 16 PAH species specified by the Environmental Protection Agency (EPA). The analyses yielded the findings that diesel vehicles had the highest mass concentration ($2,007{\mu}g/m^3$), followed by motocycle ($1,066{\mu}g/m^3$), LPG vehicle ($392{\mu}g/m^3$), and gasoline vehicles ($270{\mu}g/m^3$). The highest carbon concentrations in total particulate matter by vehicle weight were produced from LPG vehicle (79.8%), followed by gasoline vehicle (77.4%), motocycle (69.8%), and diesel vehicle (59.1%).