• 한국해양공학회지
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• 제21권2호
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• pp.12-21
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• 2007

As the economy grows and the population increases, we need to develop our coastal area and make use of it for various purposes. Specifically, investigation of the wave interactions on and around the vertical cylinders is very important in the design of the offshore or coastal structures. The nonlinear potential analysis developed so far, although very useful, has been found to be limited in application, as strong nonlinear waves generated by the interference between multilayered cylinders and wave impact forces by breaking waves can hardly be estimated. In this study, using a 3-Dimensional volume tracking method VOF(Volume of Fluid), based on Namer-Stokes equations, was developed to simulate highly nonlinear effects, such as breaking waves at the interface or complicated interference waves among structures. A numerical method for nonlinear interaction wave and vertical cylinders is newly proposed. The wave forces and wave transformations computed by the newly proposed numerical simulation method were compared to the other researcher's experimental results, and the results agree well. Based on the validation of this study, this numerical method is applied to the two vertical cylinders to discuss their nonlinear wave forces and wave transformations, according to the variations of separate distance of vertical cylinders.

• 한국지반환경공학회 논문집
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• 제20권2호
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• pp.29-40
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• 2019

최근 터널 시공 시 여러 위험요인을 감안하여 보다 안전한 터널의 시공을 위하여 해상이나 하상 밑의 연약지반에서, 도심터널공사나 주요 구조물 하부 통과를 위해서 기계화 시공의 빈도가 높아지고 있다. 그러나 굴착으로 인한 지표면의 침하거동 산정이 어려워 간편하게 예측하는 식이 필요한 실정이다. 따라서 본 연구에서는 연약지반에 병렬로 터널이 시공되어지는 경우 침하거동에 대해 보다 간단한 식과 기존에 Peck(1969)이 제안한 이론을 근거로 연약지반 및 대구경 shield 터널에서 적용 가능한 수정식을 제안하고자 하였다. 이를 위해 최대 침하량, 지반조건에 따른 침하범위, 병렬시공에 따른 간섭 체적손실 등의 장기간의 계측값을 분석하였다. 그 결과 굴착면 상부가 퇴적점토인 연약지반에서 간편하게 최대 침하량을 산정할 수 있는 식을 제시하였는데, Peck(1969)의 식보다 국내 계측데이터에 더 적합한 것으로 나타났다.

• 한국소음진동공학회논문집
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• 제15권6호
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• pp.738-748
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• 2005

The ship radiated noise level fluctuates by the difference of interference and reverberation according to measurement methods and environmental conditions. These phenomena cause error of the source level estimation even in the same environment conditions. This paper describes a quantitative analysis and a reduction method for an error value to the source level estimation in spatial and temporal interference environment. The design criteria of the radiated noise measurement array composed of omni-directional hydrophones and the source level accuracy in the deep water range are given. The source level accuracy in the shallow water range is also derived based on the statistical model of the multiple reflection paths. The results are verified using the water tank experiment and the sea trial.

• Toxicological Research
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• 제21권3호
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• pp.195-208
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• 2005

Diabetes is a major cause of morbidity and mortality, and associated with a high risk of atherosclerosis, and liver, kidney, nerve and tissue damage. Defective insulin secretion in pancreas and/or insulin resistance in peripheral tissues is a central component of diabetes. It is well established that, regardless of the degree of muscle insulin resistance, glucose levels in diabetic and non-diabetic individuals are determined by the rate of hepatic glucose production. Moreover recently studies using liver-specific insulin receptor knockout mice show the paramount role of the liver in insulin resistance and diabetes. Insulin exerts a multifaceted and highly integrated series of actions via its intracellular signaling systems. The first major section of this review defines the major insulin-mediated signaling pathways including phosphatidylinositol 3-kinase and mitogen activated protein kinases. The second major section of the review presents a summary and evaluation of methods for determination of the role and function of signaling pathways, including methods for determination of kinase phosphorylation, the use of pharmacological inhibitors of kinase and dominant-negative kinase constructs, and the application of new RNA interference methods.

• Wind and Structures
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• 제27권6호
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• pp.439-449
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• 2018

Wind loading of a tall building built amidst a group of buildings in urban environment is always greatly affected by shielding effects. Wind tunnel tests were carried out to assess the shielding provided by a row of low-rise or medium-rise buildings upstream a square-section tall building of height-to-breadth ratio 6. Mean and dynamic wind loads on the tall building were measured at different wind incidence angles and presented as interference factors (IFs). It is found that presence of a row of upstream buildings provides significant shielding to the tall building. At normal wind incidence, the mean along-wind loads and all components of fluctuating wind loads on the tall building are always reduced by shielding. Vortex shedding seems to still occur on the upper exposed part of the tall building but the vortex excitation levels are largely reduced. The degree of shielding is found to depend on a number of arrangement parameters of the row of upstream buildings. Empirical equations are proposed to quantify the shielding effect based on the wind tunnel data.

• 한국물환경학회지
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• 제37권6호
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• pp.510-519
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• 2021

Volatile Organic Compounds (VOCs) in sediments, which can cause human health problems, have been monitored in Korea since 2014. Measured VOC concentrations can be affected by matrix type and the volatility of target substances. In this study, (1) VOCs volatility and the influence of matrix interference were confirmed, and (2) internal standards (IS) method was applied to improve analytical method. For these purposes, method detection limit (MDL), calibration linearity, precision and accuracy of VOCs were compared in various matrices using the IS. Some of VOCs in sediments showed different peak areas and reduced rates compared to water matrix. It was suggested that adsorption properties of sediments hindered the migration to vapor during heat pretreatment in headspace method. A calibration curve was created in clean sand. Recovery rates for the calibration curve method and IS applying method were 64.1~83.1% and 99.1~119.3%, respectively. Relative standard deviations ranged from 11.1% to 21.6% for the calibration curve method and those for IS ranged 4.7% to 13.7%. In case of real sediment, calibration curve and 1,2-Dichlorobenzene-d4 (ODCB) among IS were not suitable. The average recovery rate of Fluorobenzene (FBZ) increased by 56.4% and Relative Standard Deviation (RSD) by 4.7%. However, the recovery rate was increased in the samples with large values of igniting intensity. This study confirmed that influence of the matrix of VOCs in sediment, and addition of IS materials improved precision and accuracy. Although IS corrects volatilization and adsorption, it is recommended that more than two types of IS should be added rather than single.

• 한국전자파학회논문지
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• 제25권9호
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• pp.944-951
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• 2014

본 논문에서는 위성의 지상국 위치를 선정함에 있어 전파 간섭을 피하고, 사용자의 위성활용도를 극대화하기 위한 지상국 위치 선정 전파 간섭 연구이다. 위성 지상국의 위치 선정을 위해 부지 확보가 용이하고, 평가지표의 평가항목별로 평가가 가능하다고 판단되는 지상국 후보지에 대해 전파 환경을 조사하고, 측정 결과를 제시하였으며, 10명의 전문가의 적합성 판단을 통해 후보지의 적합성에 대해 검토하였다. 향후 다른 후보지들의 측정 결과와 비교를 통해 최적의 지상국 위치를 선정할 수 있도록 하였다. 또한, 위성 지상국을 구축하고 있는 세계적 추세에 맞추어, 우리나라의 위성 지상국 위치 선정을 위한 정량적인 평가기준이 될 수 있다.

• 한국환경보건학회지
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• 제35권5호
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• pp.343-354
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• 2009

Since Barker found associations between low birth weight and several chronic diseases later in life, the hypothesis of fetal origins of adult disease (aka, Barker Hypothesis) and epigenetics have been emerging as a new paradigm for geneenvironment interaction of chronic disease. Epigenetics is the study of heritable changes in gene silencing that occur without any change in DNA sequence. Gene expression can be regulated by several epigenetic mechanisms, including DNA methylation and histone modifications, which may be associated with chronic conditions, such as cancers, cardiovascular disease, and type-2 diabetes. One carbon metabolism which involves the transfer of a methyl group catalyzed by DNA methyltransferase is an important mechanism by which DNA methylation occurs in promoter regions and/or repetitive elements of the genome. Environmental factors may induce epigenetic modification through production of reactive oxygen species, alteration of methyltransferase activity, and/or interference with methyl donors. In this review, we introduce recent studies of epigenetic modification and environmental factors, such as heavy metals, environmental hormones, air pollution, diet and psychosocial stress. We also discuss epigenetic perspectives of early life environmental exposure and late life disease occurrence.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1994년도 하계학술대회 논문집 C
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• pp.1517-1519
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• 1994

This paper describes electrical environmental study of a 765kV double circuit test line. Corona performance on several candidate conductor bundles has been investigated in the corona cage (single phase simulation facility) since 1984. We have known that six RAIL conductor bundle is the most suitable for the 765kV transmission Line, [3] To investigate electrical environmental impact of the future commerciale line, we build a full sacle 765kV test line in 1993. The test results of Audible Noise, Radio Interference, TV Interference from August, 1993 to Jan. 1994 were measured as $48.7[dBA](L_{50})$. $57.4[dB{\mu}V/m]$(Fair weather, $L_{50})$. $14.5[dB${\mu}$V/m]$(Fair weather, $L_{50}$). We have found that the Audible Noise data were very close to the predicted(48.5 [dBA]) by BPA Corona and Field Effects Computer program, however, the RI and TVI data were much higher than predicted(42 [dBmV/m], $7.9[dB{\mu}V/m)$ by the BPA program. We have investigating the reason of the difference. In the constructing of full scale test line, we developed the tubular tower, 765kV test transformer and hardwares of 765kV transmission line insulator strings. Also we will investigate the effects of plants under the 765kV test Line.

• 한국환경복원기술학회지
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• 제11권2호
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• pp.104-113
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• 2008

Due to the increasing needs of land supply, green space has been continuously encroached and resulted considerable naturality deterioration in Korea. In order to overcome the problem, it is necessary to introduce a integrated system for managing the quantitative and qualitative aspects of green space. With this regard, this study is to derive the feasibility for the adoption of the 'no net loss of green' policy to Korea from German and Japanese experiences. In Germany, natural resources are protected and inevitable damages were compensated through the adoption of 'interference regulation'. In Japanese case, future green space and artificial green foundation should be specified on the green basic plan which pursuit the improvement of naturality. In order to introduce the 'no net loss of green' policy to Korea, not only awareness raising on integrated green management system but also amendment of related regulations are needed. In detail, restoration and recovery on the damaged nature should be clearly elucidated and indicators to evaluate the current naturality and calculation methods for the restoration should be developed. Should this integrated green management system introduced, deterioration of naturality by development activities could be minimized thorough the adoption of land development permission criteria and green space management methodologies.