• 공업화학
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• 제28권4호
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• pp.490-494
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• 2017

최근 차량 증가와 더불어 이에 따른 사고 또한 증가하고 있는 추세로써 대부분의 사고차량에서 도색작업이 반드시 요구되고 있다. 통상적인 차량 도색시 다량의 유기용제가 사용되어 환경문제가 대두되고 있으며 이에 대처하기 위해 최근 수용성 도료가 국내에서도 개발되고 그 사용이 증가하고 있다. 그러나 수용성 도료의 경우 도장 작업비용이 고가이기에 정비공장에서 보험금 과다청구의 수단으로 악용하는 사례 또한 적지 않다. 본 연구에서는 수용성 도료를 사용하였는지 여부를 규명하기 위해 수용성 도료에 사용되는 비이온성 계면활성제 성분인 Surfynol 104 성분을 지표물질로 하여 퀴리포인트를 이용한 열분해-기체크로마토그래피/질량분석법(Py-GC/MS)으로 분석하였다. 분석결과 도색작업이 완료된 실제 차량 페인트에서 동위원소 치환된 fluoranthene-d10을 내부표준물질로 하여 표준물첨가법(standard addition method)으로 약 0.38%의 계면활성제 성분이 검출되었다.

• Proceedings of the National Institute of Ecology of the Republic of Korea
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• 제3권4호
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• pp.204-211
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• 2022

Forensic entomology is a field of study that includes the succession of insects attracted to and found on cadavers. One of its main focusses is estimating post-mortem interval (PMI) based on the growth stage of insects found in and around human cadavers. In many countries, the diversity of insect occurrence is studied in relation to the environmental conditions a cadaver may be exposed to or the effects of different clothes. In this study, changes in the decomposition process and differences in insect succession were investigated by comparing skinned and intact water deer carcasses. Five orders, 15 families, and 21 species of insects were identified, most of which were Dipteran and Coleopteran. The skinned carcass decomposed more rapidly than the intact carcass, which was linked to differences in insect succession. The difference in the decomposition rate and insect succession according to the external conditions of the carcass can be used as basic data for estimating the PMI of the carcass and setting the forensic entomological indicator species.

• Genomics & Informatics
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• 제17권3호
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• pp.24.1-24.8
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• 2019

Early environmental exposure is recognized as a key factor for long-term health based on the Developmental Origins of Health and Disease hypothesis. It considers that early-life nutrition is now being recognized as a major contributor that may permanently program change of organ structure and function toward the development of diseases, in which epigenetic mechanisms are involved. Recent researches indicate early-life environmental factors modulate the microbiome development and the microbiome might be mediate diet-epigenetic interaction. This review aims to define which nutrients involve microbiome development during the critical window of susceptibility to disease, and how microbiome modulation regulates epigenetic changes and influences human health and future prevention strategies.

• 산업융합연구
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• 제21권3호
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• pp.83-97
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• 2023

본 연구의 목적은 국립법무병원에 입원 중인 정신장애 범죄자의 정신 건강 회복에 대한 인식을 파악하는 것이다. 연구 대상자는 C 지역에 있는 국립법무병원에 입원 중인 정신장애 범죄자 91명이다. 자료수집은 정신 건강 회복에 대한 서면 질문지를 제공하여 자유롭게 기술하도록 하였으며 수집된 자료는 연구자 2인이 Krippendorff의 내용 분석 방법에 따라 분석하였다. 연구 결과, 정신 건강 회복에 대한 의미는 4개의 범주, 17개의 주제가 도출되었으며 4개의 범주는 '정신과적 증상으로부터 해방', '안정적으로 일상생활과 사회생활이 이루어짐', '희망적이고 의미 있는 삶을 살아감' 그리고 '퇴원 후 범죄 없이 살아가는 상태'이었다. 정신 건강 회복에 대한 촉진 요인 및 장애요인은 각각 4개의 범주, 14개의 주제가 도출되었으며 '치료적 요인', '개인적 요인', '대인관계 요인' 그리고 '환경요인'이었다. 본 연구 결과는 국립법무병원에 입원 중인 정신장애 범죄자의 정신 건강 회복을 위한 교육 및 중재 개발을 위한 기초자료로 사용될 수 있다.

• 한국안전학회지
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• 제35권2호
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• pp.1-7
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• 2020

In this paper, we describe fire risk of Kimchi refrigerator. The Kimchi refrigerator has been widely spread and used starting from the first half of 2000 and recently fire accidents caused by the Kimchi refrigerator emerged as social concern. In particular, in products of a specific manufacturer, it is not an environmental factor, but a characteristic that the fire is caused due to a defect of the product itself is shown. These features are judged to be formed by unique defects regardless of external factor by forming electrically arc mark in the relay element. In this paper, we analyzed the cause of the fire occurring in the Kimchi refrigerator and finally confirmed the characteristic that the fire occurred mainly in the relay element due to insufficient capacity of the relay element. Therefore, when a fire occurs in a product of the same maker as the Kimchi refrigerator mentioned in this paper, it is always judged that the inspection of the relay element should be carried out.

• 한국전자통신학회논문지
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• 제3권4호
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• pp.204-209
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• 2008

3면이 바다로 덮여있는 해양국가인 우리나라에서 해난 사고는 다양한 원인과 결과를 보여준다. 매년 600-700건씩 발생하는 해난 사고는 소형선박인 어선이 대부분을 차지하고 있으며, 연안에서 발생하는 선박과 조업하는 어선과의 충돌, 유조선의 침몰등으로 인한 인명손실과 대규모의 환경오염에 대한 책임, 실종선박에 대한 수색 등은 반복되는 해난 사고의 유형이다. 21세기가 시작되면서 대형화된 선박과 선원들의 감소로 인하여 디지털 선박이 등장하게 되었고, 선박에 설치된 장비들에 대하여 디지털 데이터가 저장되고, 저장된 데이터 속에서 필요한 정보를 추출하고 분석하는 해상 디지털 포렌식이 필요하게 되었다. 해난 사고에 대한 원인 규명과 책임, 손해 배상 등을 다투기 위한 증거를 수집하는 방안으로 해상 디지털 포렌식을 제안하며 이를 이용하여 디지털 증거를 수집하는 방안을 제시한다.

• 약학회지
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• 제53권5호
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• pp.293-297
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• 2009

The abuse of methamphetamine (MA) is one of the most serious drug abuses in Asia. And, the prevention of precursor production for abuse drug is one of the most effective drug control system. Isotope ratio analysis at natural abundance levels have been used to establish the environmental source or the geographic origin of various biological and nonbiological materials. Ephedrine, the precursor of MA, is produced by one of three methods; extraction from Ephedra plants, full chemical synthesis or via a semi-synthetic process involving the fermentation of sugar, followed by amination. We investigated the origin of ephedrine and pseudoephedrine based on the carbon and nitrogen values for nineteen pharmaceutical powder materials (PPMs) obtained from pharmaceutical company in Korea by stable isotope ratio mass spectrometry coupled to an elemental analyser (EA-IRMS). The carbon delta values for the ephedrine and pseudoephedrine were -24.21~-22.72 (mean=-23.72) $^{\cir}/_{\circ\circ}$ and -23.79~-22.71 (mean=-23.48) $^{\cir}/_{\circ\circ}$. The nitrogen delta values were 3.51~5.55 (4.43) $^{\cir}/_{\circ\circ}$ and 2.24~8.22 (5.42) $^{\cir}/_{\circ\circ}$. These results indicate that PPMs are semi-synthetic products. Therefore the origins of ephedrine(natural, semi-synthetic or synthetic) could be discriminated by using carbon and nitrogen stable isotope ratios. we are sure tat this stable isotope ratio analysis can discriminate the origins of precursors of methamphetamine.

• Mass Spectrometry Letters
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• 제7권2호
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• pp.31-40
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• 2016

The analysis of nuclear materials and environmental samples is an important issue in nuclear safeguards and nuclear forensics. An analysis technique for safeguard samples has been developed for the detection of undeclared nuclear activities and verification of declared nuclear activities, while nuclear forensics has been developed to trace the origins and intended use of illicitly trafficked nuclear or radioactive materials. In these two analytical techniques, mass spectrometry has played an important role in determining the isotope ratio of various nuclides, contents of trace elements, and production dates. These two techniques typically use similar analytical instruments, but the analytical procedure and the interpretation of analytical results differ depending on the analytical purpose. The isotopic ratio of the samples is considered the most important result in an environmental sample analysis, while age dating and impurity analysis may also be important for nuclear forensics. In this review, important aspects of these techniques are compared and the role of mass spectrometry, along with recent progress in related technologies, are discussed.

• Toxicological Research
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• 제3권2호
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• pp.89-96
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• 1987

To test the efficacies of thiosulfate in cyanide poisoning with or without oxygen, after the administration of sublethal dose of potassium cyanide, serial arterial blood samples were collected during 60 minutes in 15 rabbits. Cyanide ion concentrations were measured by Conway cell microdiffusion method, and arterial oxygen tensions were also observed. Comparison of elimination constants showed that arterial blood cyanide ion concentration decreased most rapidly in the thiosulfate with oxygen-administered group. The elimination of cyanide ion by the action of thiosulfate in acutely poisoned rabbit accelerated probably due to oxygen and elimination pattern seems to occur by first-order elimination kinetics.

• Toxicological Research
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• 제24권1호
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• pp.51-58
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• 2008

The present study was designed to explore the immunotoxic effects of orally administered aluminum (AI) on pregnant rats (n = 60) and their growing fetuses and consequently on the animal wealth. The animals were randomly allocated into three equal groups of 20 rats each. The first group has no treatment and kept as a control (G1). The second and third groups of pregnant rats were treated orally with aluminum chloride at 345 mg/Kg b.wt. The second group (G2) received the tested compound from the $6^{th}$ day of gestation to the end of weaning, whereas the third group (G3) received the tested compound from the $15^{th}$h day of gestation to the end of weaning. Control and treated animals (dams and offspring) were immunized ip with (0.5 ml) 20% sheep red blood cell (SRBC) suspension seven days before the end of experiments. At the end of exposure, ten dams and ten offspring from each group were used for assessment of cell-mediated immunity and a similar number of animals were sacrificed for evaluating the humoral immune response and serum protein profile. Aluminum chloride exposure of dams ($G_2&G_3$) caused significant suppression of both cell mediated and humoral immune responses in the obtained offsprings compared to the control group ($G_1$) without any significant effect on the immune responses of these dams. Moreover, the serum total globulins, albumin/ globulin (A/G) ratio and gamma globulin fraction were significantly decreased in the treated dam's offsprings compared to the corresponding controls while the serum total protein and all serum protein fractions showed non significant difference between the control and treated dams and between the two treated dam groups themselves. There were no histopathological changes observed in thymus, spleen and liver of the control and treated dams. Thymus of treated dam's offsprings (G2) showed lymphoid depletion in both cortex and medulla. Their spleens showed lymphoid depletion in the white pulps and congestion with hemosiderosis in the red pulps. Liver of treated dam's offsprings showed dilation and congestion of its central vein with degenerative changes in the hepatocytes. These histopathological changes were more severe in G2 than in G3 offsprings. It can be concluded that gestational and/ or lactation exposure of pregnant dams to AI chloride caused suppression of both cellular and humoral immune responses of their offsprings.