• Development and Reproduction
• /
• v.9 no.1
• /
• pp.1-5
• /
• 2005

The hypothalamo-pituitary-gonadal hormone axis is centrally controlled by a complex regulatory network of excitatory and inhibitory signals, that is dormant during infantile and juvenile periods and activated at puberty. The kisspeptins are the peptide products of the KiSS-1 gene and the endogenous agonists for the G protein-coupled receptor 54(GPR54). Although KiSS-1 was initially discovered as a metastasis suppressor gene, a recent evidence suggests the KiSS-1/GPR54 system is a key regulator of the reproductive system. Yet the actual role of the KiSS-1/GPR54 system in the neuroendocrine control of gonadotropin secretion remains largely unexplored, the system could be the first missing link in the reproductive hormonal axis. Central or peripheral administration of kisspeptin stimulates the hypothalamic-pituitary-gonadal axis, increasing circulating gonadotropin levels in rodents, sheep, monkey and human models. These effects appear likely to be mediated via the hypothalamic GnRH neuron system, although kisspeptins may have direct effects on the anterior pituitary gland. The loss of function mutations of the GPR54(GPR54-/-) have been associated with lack of puberty onset and idiopathic hypogonadotropic hypogonadism(IHH). So kisspeptin infusion may provide a novel mechanism for HPG axis manipulation in disorders of the reproductive system.

• Journal of Korean Society of Environmental Engineers
• /
• v.32 no.5
• /
• pp.499-508
• /
• 2010

This study proposed a life cycle impact assessment index that can indicate the environment-related information of the product in monetary value such that the national geographical, environmental, and social features are fully reflected based on a damage-oriented model. First, the estimation process was classified into characterization, damage assessment, and integration stages considering the six biggest impact categories: resource depletion, global warming, ozone depletion, acidification, eutrophication, and photochemical oxidant creation. Moreover, this study came up with the 16 category endpoints related to the 6 impact categories, and the damage function, to the 4 largest safeguard subjects. The integration indices of finally identified impact categories were KRW 21.8/kg Sb, KRW 6.19/kg$CO_2$, KRW 53,000/kg CFC-11, KRW 13,100/kg $SO_2$, KRW 2,310/kg ${PO_4}^{3-}$, and KRW 3,030/kg $C_2H_4$. Using the results of this research, environmental impacts based on the environmental load generated throughout the entire life cycle of a product can serve as a single index in monetary value; thus enhancing understanding and utilization of the results of life cycle impact assessments.

• Journal of Korean Society of Environmental Engineers
• /
• v.31 no.11
• /
• pp.1033-1040
• /
• 2009

One thing to note in cyclone operation and design is to minimize the pressure drop with the enhancement of the efficiency of dust collection. This can be facilitated by the detailed resolution of complex fluid flow occurring inside a cyclone. To this end, the main objective of this study was to obtain the detailed fluid dynamics by the development of a reliable computation method and thereby to figure out the physics of dust collection mechanism for more extreme environment caused by high temperature and pressure condition. First of all, the computer program developed was evaluated against experimental result. That is, the numerical calculation predicts well the data of experimental pressure drop as a function of flow rate for the elevated pressure and temperature condition employed in this study. The increase of pressure and temperature generally affects significantly the collection efficiency of fine particle but the effect of pressure and temperature appears contrary each other. Therefore, the decrease of collection efficiency caused by the high operating temperature mainly due to the decrease of gaseous density can be remedied by increase of operating pressure. After the evaluation of the program, a series of parametric investigations are performed in terms of major cyclone design or operating parameters such as tangential velocity and vortex finder diameter for dusts of a certain range of particle diameters, etc. As expected, tangential velocity plays the most important effect on the collection efficiency. And the efficiency was not affected significantly by the change of the length of vortex finder but the diameter of vortex finder plays an important role for the enhancement of collection efficiency.

• Journal of Korea Technology Innovation Society
• /
• v.17 no.1
• /
• pp.95-123
• /
• 2014

Recently, as the role of science and technology in social domain is more increased and the creative economy becomes a important matter in national development strategy, it is necessary that the improvement of legal system on science and technology for efficiently responding to paradigm shift into Innovation driven science and technology policy. Especially, The Framework Act On Science And Technology as a general and basic norm on science and technology policy is necessary to revise in systematic and substantial aspect in order to correspond with changed environment and current of the times. The Framework Act On Science And Technology was established in 2001 and revised several times, but substantial amendment reflecting the political facts as the need to demand was insufficient because it was revised only related with restructuring the government organization and changing the S&T Policy Coordinating Committee system. And therefore, this paper aims to review the problems and complementary factors and suggest the improvement draft on The Framework Act On Science And Technology. According to study, the revision methodologies are following : first, the Chapter and Paragraph of the law should be restructured to improve the systemicity, next the comprehensiveness, effectiveness, connections with related special laws and compatibility of the law should be complemented by adding the new provision or amending the inadequate provision to improve the position and function as a general and basic norm.

• Korean Journal of Cognitive Science
• /
• v.16 no.4
• /
• pp.369-386
• /
• 2005

Although Intelligent Tutoring System(ITS) offers individualized learning environment that overcome limited function of existent CAI, and consider many learners' variable, there is little development to be using at the sites of schools because of inefficiency of investment and absence of pedagogical content knowledge representation techniques. To solve these problem, we should study a method, which represents knowledge for ITS, and which reuses knowledge base. On the pedagogical content knowledge, the knowledge in education differs from knowledge in a general sense. In this paper, we shall primarily address the multi-complex structure of knowledge and explanation of learning vein using multi-complex structure. Multi-Complex, which is organized into nodes, clusters and uses by knowledge base. In addition, it grows a adaptive knowledge base by self-learning. Therefore, in this paper, we propose the 'Extended Neural Logic Network(X-Neuronet)', which is based on Neural Logic Network with logical inference and topological inflexibility in cognition structure, and includes pedagogical content knowledge and object-oriented conception, verify validity. X-Neuronet defines that a knowledge is directive combination with inertia and weights, and offers basic conceptions for expression, logic operator for operation and processing, node value and connection weight, propagation rule, learning algorithm.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.3
• /
• pp.327-332
• /
• 2017

As Internet of Things (IoT) technology advances, there is a growing demand for location-based services (LBSs) to identify users' mobility and identity. The initial LBS system was mainly used to measure position information by measuring the phase of a signal transmitted from a global positioning system (GPS) satellite or by measuring distance to a satellite by tracking the code of a carrier signal. However, the use of GPS satellites is ineffective, because it is difficult to receive satellite signals indoors. Therefore, research on wireless communications systems like ultra-wide band (UWB), radio frequency identification (RFID), and ZigBee are being actively pursued for location recognition technology that can be utilized in an indoor environment. In this paper, we propose an LBS system that includes the 2.45GHz band for chirp spread spectrum (CSS), and the 3.1-10.6GHz band and the 250-750MHz bands for UWB using the IEEE 802.15.4a standard for low power-based location recognition. As a result, we confirmed that the 2.45GHz Industrial, Scientific and Medical (ISM) band RF transceiver and the ranging function can be realized in the hardware and has 0dBm output power.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.15 no.6
• /
• pp.714-719
• /
• 2005

The paper attempts to design and implement the system which can remotely check visitors' speech or Image by a mobile phone. This system is designed to recognize who a visitor is through the automatic calling service, not through a short message, via the mobile phone, even when the home owner is outside. In general, door locks are controlled through the home Server, but it is more effective to control door locks by using DTMF signal from a real-time point of view. The technology suggested in this paper makes it possible to communicate between the visiter and the home owner by making a phone call to tile home owner's mobile phone automatically when the visiter visits the house even if the home owner is outside, and if necessary, it allows for the home owner to control the door lock remotely. Thanks to the system, the home owner is not restricted by time or space for checking the visitor's identification and controlling the door lock. In addition, the security system is improved by changing from the existing password form to the combination of password and speaker verification lot the verification procedure required for controlling the door lock and setting the environment under consideration of any disadvantages which may occur when the mobile Phone is lost. Also, any existing problems such as reconnection to tile network for controlling tile door lock are solved by controlling the door lock in real time by use of DTMF signal while on the phone.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.19 no.6
• /
• pp.65-71
• /
• 2019

Conventional methods of measuring ground resistance and ground resistance field measurement are used to measure voltage drop according to the resistance value of the site by applying current by installing a constant interval of measurement electrode. If the stratified structure of the site site is unique, errors in boundary conditions will occur in the event of back acid and the analysis of the critical ground resistance in the ground design will show much difference from simulation. This study utilizes the Arduino module and smart ground measurement technology in the convergent information and communication environment to develop a reliable smart land resistance measuring device even if the top layer of land is unique, to analyze the land resistance and accumulate data to predict the change in the age of the land. Considering the topographical characteristics of the site, we propose a ground resistance measuring device and its method of measuring ground resistance so that the auxiliary electrode can be installed by correctly positioning the angle and distance in measuring ground resistance. Not only is ground resistance value obtained through electrodes installed to allow accurate ground resistance values to be selected, but it can also be used as a useful material for installing electrical facilities in similar areas. Moreover, by utilizing reliable data and analyzing the large sections of the site, a precise analysis of the site, which is important in ground design as well as construction cost, is expected to be used much in ground facility design such as potential rise.

• The Journal of the Korea Contents Association
• /
• v.11 no.1
• /
• pp.50-55
• /
• 2011

This paper describes methodology which enables user in order to play multiplex channel media at realtime to augment a various advertisement effect efficiently. This method implemented from the computer environment where DirectX SDK, DirectShow and MS Visual Studio 2008 etc. are established. This media player have or hide the menu interface for reads the media. The experimental data which are used in the media player is mostly video. We added the area where has the function of Banner Ticker and GIF Animation in the media player in order augmenting an advertisement effect. All medias come to separate with video and audio by Splitter. Then that respectively execute Decoder and Render. Also the media player are possible video mixing using an alpha channel. This paper used VMR-9 of DirectShow for this. The player which sees to use multiplex channel, to remake the various medias simultaneously. Therefore, this player which sees advertisement effect of the form which is various positively in the users, has the advantage which is the possibility to recognize. This paper use tried the media player using experimental data and compare the existing media player and the media player which proposes from functional differences for an advertisement effect.

• Therapeutic Science for Rehabilitation
• /
• v.9 no.3
• /
• pp.7-21
• /
• 2020

Objective : The aim of this systematic review is to analyze the assessment items and tools used for the discharge of stroke and elderly patients and to help select appropriate assessment tools for discharge planning. Methods : The studies included in this review were collected from the PubMed, Medline Complete (EBSCOhost), and Scopus databases from January 2009 to December 2018. A total 22 studies were selected. The research types, the areas and sub-areas of assessment, as well as the assessment tools according to the areas were analyzed. Results : Descriptive research (59.2%) was the most frequent type of research. The 12 main areas of assessment were medical condition, activities of daily living, swallowing function, sensation, mobility, cognition and perception, communication, emotion, home environment, patient knowledge and readiness for discharge, social support, and well-being. Among the assessment tools, the most frequently used tools were Bathel Index; Functional Independence Measure, to assess activities of daily living; Short-Form Health Survey, to assess well-being, and Timed Up and Go test, to assess mobility. Conclusion : This study will help select the assessment areas and tools to be considered at discharge of stroke patients and serve a basis for the development of comprehensive assessment tools for discharge planning.