• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2013년도 춘계 학술논문 발표대회
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• pp.256-257
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• 2013

Roof and exterior wall of general formal buildings are designed and constructed through design focused exterior wall system and drainage and waterproof roof system. However, there are no classification of exterior wall and roof in freeform buildings and they are integrated as a surface of freeform buildings. Therefore it is necessary to develop the dry roof construction method using double skin roof system satisfying the design and function of the envelope. In this study, we have an effort to develop construction method of double-skin roof system using metal panel and PV.

• 한국군사과학기술학회지
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• 제5권1호
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• pp.37-44
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• 2002

An echo signal in the active sonar using a high frequency is mainly formed of a specular reflection from the surface of an object along with several equivalent scatter inside, which are characterized by the spatial distribution of the highlights on the object. This thesis proposed a model in which the synthesized echo signal can be expressed as a distributed simulated target. The proposed model is obtained after composing a signal based on the movement of highlights relative to the aspect angle from the discontinuous point of an external hull with a strong reflection from a spheroid underwater target. Because the proposed algorithm includes a synthesis of the signals related to the highlight spacial distribution, it can be applied to all kinds of systems used at a short range, and similar results were obtained to the actual measured results of all reflected signals in previous literature referring to the irregular factor application of an envelope.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 추계학술대회 논문집
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• pp.204-207
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• 2005

We discuss two possibilities of using femtosecond pulse lasers as a new interferometric light source fer enhanced precision surface profile metrology. First, a train of ultra-fast laser pulses yields repeated low temporal coherence, which allows performing unequal-path scanning interferometry that is not feasible with white light. Second, high spatial coherence of femtosecond pulse lasers enables to test large size optics in non-symmetric configurations with relatively small size reference surfaces. These two advantages are verified experimentally using Fizeau and Twyman-Green type scanning interferometers.

• Applied Microscopy
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• 제48권4호
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• pp.96-101
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• 2018

The release of nanoscale membrane-bound vesicles is common in all three domains of life. These vesicles are involved in a variety of biological processes such as cell-to-cell communication, horizontal gene transfer, and substrate transport. Prokaryotes including bacteria and archaea release membrane vesicles (MVs) (20 to 400 nm in diameter) into their extracellular milieu. In spite of structural differences in cell envelope, both Gram-positive and negative bacteria produce MVs that contain the cell membrane of each bacterial species. Archaeal MVs characteristically show surface-layer encircling the vesicles. Filamentous fungi and yeasts as eukaryotic microbes produce bilayered exosomes that have varying electron density. Microbes also form intracellular vesicles and minicells that are similar to MVs and exosomes in shape. Electron and fluorescence microscopy could reveal the presence of DNA in MVs and exosomes. Given the biogenesis of extracellular vesicles from the donor cell, in situ high-resolution microscopy can provide insights on the structural mechanisms underlying the formation and release of microbial extracellular vesicles.

• 천문학회지
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• 제41권5호
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• pp.121-137
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• 2008

We present optical and near-infrared imaging and long-slit spectroscopy for the blue compact dwarf galaxy (BCD) Mrk 49 in the Virgo Cluster. The surface brightness distribution analysis shows that Mrk 49 consists of an off-centered blue bright compact core of r = 10" and a red faint outer exponential envelope. The $H_{\alpha}$ image and color difference suggest that these two components have different stellar populations: a high surface brightness population of massive young stars and an underlying low surface brightness population of older stars. The redder near-infrared colors of the inner most region suggest that the near-infrared flux of Mrk 49 originates from evolved massive stars associated with the current star-forming activity. The total apparent magnitude is $B_T\;=\;14.32$ mag and the mean effective surface brightness is ${\mu}_{eff}(B)\;=\;21.56$ mag $arcsec^{-2}$. Long-slit spectroscopy shows that Mrk 49 rotates apparently as a solid body within r = 10" in a plane at position angle 55 degrees with an amplitude of about $20\;km\;sec^{-1}$. The measured radial velocity of Mrk 49 was derived as $1,535\;km\;sec^{-1}$; and the total mass of stars and gases is in the range of 3 to $6\;{\times}\;10^9\;M_{\odot}$. The mass-to-light ratios for the central region of Mrk 49 in I and B band are estimated 1.0 and 0.5, respectively. The upper limit of the dark matter to visible matter ratio seems to be < 5. The oxygen abundance is $12\;+\;\log(O/H)\;=\;8.21\;{\pm}\; 0.1$ which is about one quarter of the solar value while the relative helium abundance appears to be similar to that of the sun.

• 한국터널지하공간학회 논문집
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• 제14권4호
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• pp.293-308
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• 2012

암반 절리면과 같이 입자와 연속체 평면의 접촉면에서의 전단거동은 전체 구조물의 거동을 지배할 수 있다. 암반설계의 효율을 높이기 위해서는 입자와 연속체 평면의 접촉면 전단거동 메커니즘에 대한 기초적인 이해와 접촉면 전단강도를 정확하게 산정하는 것이 필수적이다. 본 연구에서는 연속체 평면의 표면 거칠기의 영향을 알아보기 위하여 개별요소법 수치해석 프로그램인 $PFC^{2D}$를 사용하였다. 이 때 표면 거칠기는 매끄러운 평면, 중간 거칠기 평면, 거친 평면의 세 가지로 구분하였다. 접촉면 전단시험에서 입자 형상 및 입자 파쇄의 영향을 연구하기 위하여 one ball 모델과 clump 및 cluster 모델을 형성하여 상대적으로 비교 분석하였다. 이 때 입자의 형상은 원형, 삼각형, 직사각형, 정사각형으로 모델링하였다. 수치해석 결과, 표면 거칠기가 클수록 접촉면 전단강도 및 마찰각이 크게 나타났으며, 또한 간극률이 크게 증가하였다. 표면이 매끄러운 one ball 모델보다 작은 입자들의 결합으로 이루어져 표면이 굴곡진 모델, 즉 clump 모델의 접촉면 전단강도 및 마찰각이 크게 나타났다. 입자의 결합이 파괴되는 모델, 즉 cluster 모델의 접촉면 전단 강도 및 마찰각이 같은 형상의 clump 모델보다 작게 나타났으며, 파괴포락선은 비선형으로 나타났다. 이러한 결과로부터 연속체 평면의 거칠기 및 입자의 형상이 입자와 평면의 접촉면 전단거동 특성에 미치는 영향을 확인하였다.

• 미생물학회지
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• 제21권2호
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• pp.61-70
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• 1983

Synchronized cat kidney cells chronically infected with feline leukemia virus (FeLV) were used to study virus production, the synthesis of group specific antigen (gag) and envelope (env) proteins, the expression of env protein on the cell surface during the cell cycle, and the stability of viral RNA. As detecting method, we developed the radioimmunoassay (RIA) system using beta-emission of $^{131}I$ and demonstrated the validity of this system by comparison with routine RIA system using gamma-emission of $^{125}I$. The produced virus was analysed by developed RIA interval was determined by measuring reverse transcriptase activity. The results show that infected cells produce the complete virus particle containing products of gag, env and pol genes of FeLV, and maximum virus production occurs during mitosis of synchronized cells. Labeling of the cell surface of synchronized cells with $^{131}I$ shows that the amount of $gp70^{env}$ on the cell surface parallels cellular gorwth. Therefore, the cell cycle-dependent release of virus is not petition RIA of synchronized cells with $^{131}I$ labeled viral proteins synthesis during the cell cycle. The rate of synthesis of gag protein shows three peaks, corresponding to the $G_1,\;late\;S\;and\;late\;G_2$ phases of cell cycle. But the rate of synthesis of env protein dose not change, suggesting that in these cells the synthesis of these two gene products in controlled seperately. In Actionomycin D treated cells, the synthesis of viral proteins decreased sharply from 8 hours after treatment, and the late S and $G_2$ peaks of gag protein synthesis were disappeared. This shows the stability of viral RNA for about 6 hours in the absence of continuing viral RNA synthesis.

• 응용통계연구
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• 제30권3호
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• pp.441-451
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• 2017

본 논문에서는 주파수공간에서의 주성분 분석을 사용하여 기상자료를 분석하고자 한다. 주파수공간에서의 주성분분석은 차원축소를 위해서도 사용되지만, 주요한 패턴을 뽑아내는 데 사용되는 통계적 방법 중 하나이다. 일반적으로 주파수공간에서의 주성분 분석은 두 가지의 방법이 있는데, Hilbert PCA와 frequency domain PCA가 그것이다. 본 논문에서는 기존의 시간공간 주성분 분석과 함께 두 가지 주파수공간 주성분 분석 방법을 비교하였다. 시뮬레이션 자료를 통하여 주파수공간 주성분 분석 방법의 유용성을 보였으며, 열대 태평양 지역의 해수표층 온도값에 주성분 분석 방법들을 적용하여 기상자료 분석에 대한 유용성을 확인하였다.

• 국제초고층학회논문집
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• 제7권1호
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• pp.17-32
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• 2018

This paper explores the function of a structural skin with an embossed surface applicable to use for tall building structures. The major diagrid system with a secondary embossed surface structure provides an enhanced perimeter structural system by increasing tube section areas and reduces aerodynamic loads by disorienting major organized structure of winds. A parametric study used to investigate an optimized configuration of the embossed structure revealed that the embossed structure has a structural advantage in stiffening the structure, reducing lateral drift to 90% compared to a non-embossed diagrid baseline model, and results of wind load analysis using computational fluid dynamics, demonstrated the proposed embossed system can reduce. The resulting undulating embossed skin geometry presents both opportunities for incorporating versatile interior environments as well as unique challenges for daylighting and thermal control of the envelope. Solar and thermal control requires multiple daylighting solutions to address each local façade surface condition in order to reduce energy loads and meet occupant comfort standards. These findings illustrate that although more complex in geometry, architects and engineers can produce tall buildings that have less impact on our environment by utilizing structural forms that reduce structural steel needed for stiffening, thus reducing embodied $CO^2$, while positively affecting indoor quality and energy performance, all possible while creating a unique urban iconography derived from the performance of building skin.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5463-5467
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• 2012

Hepatitis B virus (HBV) infection is contagious with transmissiobn vertically or horizontally by blood products and body secretions. Over 50% of Iranian carriers contracted the infection prenatally, making this the most likely route of transmission of HBV in Iran. To evaluate the resistance to adefovir (ADV) therapy in patients with chronic hepatitis B infection, a study was conducted on 70 patients (63 males and 7 females), who had received in first line lamivudine and second line adefovir. All were tested for the presence of hepatitis B surface antigen (HBsAg), hepatitis B envelope antigen (HBeAg), serum alanine amino transferase (ALT) level and HBV DNA load before and after treatment with ADV. In all samples, resistance to lamivudine and ADV was tested with real time PCR. Among seventy patients with chronic hepatitis B infection, 18 (25.7%) were resistant to LAM and 8 (11.4%) were resistant to ADV. Only one patient was negative for the presence of HBS-Ag (5.6%) and two were negative for HBe-Ag (11.1%). In this study we used a new method (ALLGIO probe assay) that has high sensitivity in detection of adefovir resistance mutants, which we recommend to other researchers. Mutant strains of the YMDD motif of HBV polymerase can be found in some patients under treatment with lamivudine and ADV. ADV has been demonstrated to be efficient in patients with lamivudine resistant HBV.