• Journal of the Korean Association of Geographic Information Studies
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• v.26 no.1
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• pp.56-68
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• 2023

A system that extracts seabed topographic information by simultaneously and continuously observing the horizontal position and water depth in the sea by combining a single beam echosounder and GNSS was constructed. By applying the developed system to actual measurements of small-scale sea areas, the effectiveness of bathymetry and sea-floor topographic data acquisition using GNSS and echosounder was examined. By using the developed outdoor program DS-NAV and indoor program DS-CAD and applying the tide level data at the time of actual measurement of the target sea area, it was possible to derive bathymetry results based on the datum level i.e. approximate lowest low water level(A.L.L.W). By using the developed outdoor program DS-NAV and indoor program DS-CAD and applying the tide level data at the time of actual measurement of the target sea area, it was possible to derive the results of bathymetric survey based on the datum level. From database built through the actual measurement. it was possible to create 3D model of the sea-floor topography and extract cross-sections. The results of this study are expected to be economically useful for extracting seabed topographical information from small sea areas or in dredging sites for offshore construction.

• Korean Journal of Ecology and Environment
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• v.55 no.1
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• pp.76-83
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• 2022

We attempted to estimate potential habitats of Clithon retropictus and to determine the community structure of benthic macroinvertebrates by presence of C. retropictus. 2016 to 2018 database of "Survey and Assessment of Estuary Ecosystem Health" by the Ministry of Environment were used to identify the distribution site of C. retropictus. The occupancy model was applied to estimate the potential habitat of C. retropictus. Four diversity indices were used to confirm the community structure of benthic macroinvertebrates. C. retropictus was found in the southern coast area and part of the east coast, and this pattern was consistent with previous studies. Additionally, the occupancy model predicted that a potential habitat of C. retropictus could appear in the west coast area. The community structure of benthic macroinvertebrates was relatively high at the site with C. retropictus than the site without C. retropictus. Therefore, the occupancy model can be considered when conserving C. retropictus inhabiting a limited area. Additionally, C. retropictus can be used to the indicator species that can represent the brackish water environment.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.2
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• pp.281-290
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• 2022

In Korea, the number of national facilities for which a safety inspection is mandatory is increasing, and a safer safety inspection method is needed. This study aimed to increase the efficiency of the bridge safety inspection by enabling rapid exterior inspection while securing the safety of inspectors by using drones to perform the safety inspections of bridges, which had mainly relied on visual inspections. For the research, the Youngjong Grand Bridge in Incheon was selected as a test bed and was divided into four parts: the warren truss, suspension bridge main cable, main tower, and pier. It was possible to establish a five-step standard procedure for drone safety inspections. The step-by-step contents of the standard procedure obtained as a result of this research are: Step 1, facility information collection and analysis, Step 2, analysis of vulnerable parts and drone flight planning, Step 3, drone photography and data processing, Step 4, condition evaluation by external inspection, Step 5, building of external inspection diagram and database. Therefore, if the safety inspections of civil engineering facilities including bridges are performed according to this standard procedure, it is expected that these inspection can be carried out more systematically and efficiently.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.5C
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• pp.293-301
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• 2008

Soil profiling is one of the most important work among geotehnical engineering practice. Generally, soil profile is estimated from the observation of soil samples during subsurface exploration but such estimation also includes some experiencing aspects such as flushed water from the borehole, slime colour, boring speed and so on. In addition, since the capacity of hydraulic drill rig is significantly increased, thin layers might be easily missed. So, continuous soil profile is almost impossible over all depth to be bored from conventional subsurface exploration. While CPT or CPTu can serve continuous soil profile information over all depth generally in 5cm interval. Many charts or methods for soil profile from CPT result have been proposed during last several decades over the world. However they have not been verified in local ground condition in Korea. In this research, CPT results and soil classification results based on USCS were compiled from 17 sites over the Korea. Soil classification results by using 7 CPT soil classification charts were compared with those of USCS for the compiled database. Most proper CPT soil classification chart for Korean soil characteristics was evaluated and effective parameters for the soil classification from CPT were discussed. Finally interrelationship between CPT soil classification chart and USCS soil classification was evaluated.

• Journal of Life Science
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• v.33 no.11
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• pp.944-949
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• 2023

The purpose of this study was to identify conserved metabolic pathways and conserved genes in 122 archaeal species. Using the Clusters of Orthologous Groups of Proteins (COG) database of conserved genes, we analyzed whether 122 species had 63 COG metabolic pathways, the 822 COGs that compose them, and a total of 4,877 COGs. Archaeal ribosomal proteins were the most conserved in metabolic pathways. 46 COGs in seven COG pathways among 63 COG pathways and 20 COGs in others were conserved in 122 species. Some genes involved in cell wall and extracellular matrix synthesis, replication, transcription, translation, and protein metabolism were common to all 122 species. When the distance value of the phylogenetic tree was analyzed at the phylum level or class level, the average was the lowest at the class Halobacteria of the phylum Euryarchaeota. Standard deviation was high for the class Nitosospharia of the phylum Thaumarchaeota, the unclassified members of phylum Thaumarchaeota, the class Halobacteria of the phylum Euryarchaeota, the class Thermoprotei of the phylum Crenarchaeota, and other archaea. Furthermore, the phylogenetic tree analysis revealed six commonalities. The results of this study, along with data on conserved genes, could be used for drug development and gene selection for strain improvement.

• Tunnel and Underground Space
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• v.33 no.6
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• pp.594-609
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• 2023

TBM (Tunnel Boring Machine) method is gaining popularity in urban and underwater tunneling projects due to its ability to ensure excavation face stability and minimize environmental impact. Among the prominent models for predicting disc cutter life, the NTNU model uses the Cutter Life Index(CLI) as a key parameter, but the complexity of testing procedures and rarity of equipment make measurement challenging. In this study, CLI was predicted using multiple linear regression analysis and tree-based machine learning techniques, utilizing rock properties. Through literature review, a database including rock uniaxial compressive strength, Brazilian tensile strength, equivalent quartz content, and Cerchar abrasivity index was built, and derived variables were added. The multiple linear regression analysis selected input variables based on statistical significance and multicollinearity, while the machine learning prediction model chose variables based on their importance. Dividing the data into 80% for training and 20% for testing, a comparative analysis of the predictive performance was conducted, and XGBoost was identified as the optimal model. The validity of the multiple linear regression and XGBoost models derived in this study was confirmed by comparing their predictive performance with prior research.

• Journal of the Korean Chemical Society
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• v.68 no.3
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• pp.151-159
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• 2024

Indian spices are well known for their numerous health benefits, flavour, taste, and colour. Recent Advancements in chemical technology have led to better extraction and identification of bioactive molecules (phytochemicals) from spices. The therapeutic effects of spices against diabetes, cardiac problems, and various cancers has been well established. The present in silico study aims to investigate the binding affinity of 29 phytochemicals from 11 Indian spices with two prominent proteins, BCL3 and CXCL10 involved in invasiveness and bone metastasis of breast cancer. The three-dimensional structures of 29 phytochemicals were extracted from PubChem database. Protein Data Bank was used to retrieve the 3D structures of BCL3 and CXCL10 proteins. The drug-likeness and other properties of compounds were analysed by ADME and Lipinski rule of five (RO5). All computational simulations were carried out using Autodock 4.0 on Windows platform. The proteins were set to be rigid and compounds were kept free to rotate. In-silico study demonstrated a strong complex formation (positive binding constants and negative binding energy ΔG) between all phytochemicals and target proteins. However, piperine and sesamolin demonstrated high binding constants with BCL3 (50.681 × 10³ mol^-1, 137.76 × 10³ mol^-1) and CXCL10 (98.71 × 10³ mol^-1, 861.7 × 10³ mol^-1), respectively. The potential of these two phytochemicals as a drug candidate was highlighted by their binding energy of -6.5 kcal mol^-1, -7.1 kcal mol^-1 with BCL3 and -6.9 kcal mol^-1, -8.2 kcal mol^-1 with CXCL10, respectively coupled with their favourable drug likeliness and pharmacokinetics properties. These findings underscore the potential of piperine and sesamolin as drug candidates for inhibiting invasiveness and regulating breast cancer metastasis. However, further validation through in vitro and in vivo studies is necessary to confirm the in silico results and evaluate their clinical potential.

• Journal of the Korean Society of Radiology
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• v.81 no.5
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• pp.1164-1174
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• 2020

Purpose To evaluate a deep learning model to predict recurrence of thyroid tumor using preoperative ultrasonography (US). Materials and Methods We included representative images from 229 US-based patients (male:female = 42:187; mean age, 49.6 years) who had been diagnosed with thyroid cancer on preoperative US and subsequently underwent thyroid surgery. After selecting each representative transverse or longitudinal US image, we created a data set from the resulting database of 898 images after augmentation. The Python 2.7.6 and Keras 2.1.5 framework for neural networks were used for deep learning with a convolutional neural network. We compared the clinical and histological features between patients with and without recurrence. The predictive performance of the deep learning model between groups was evaluated using receiver operating characteristic (ROC) analysis, and the area under the ROC curve served as a summary of the prognostic performance of the deep learning model to predict recurrent thyroid cancer. Results Tumor recurrence was noted in 49 (21.4%) among the 229 patients. Tumor size and multifocality varied significantly between the groups with and without recurrence (p < 0.05). The overall mean area under the curve (AUC) value of the deep learning model for prediction of recurrent thyroid cancer was 0.9 ± 0.06. The mean AUC value was 0.87 ± 0.03 in macrocarcinoma and 0.79 ± 0.16 in microcarcinoma. Conclusion A deep learning model for analysis of US images of thyroid cancer showed the possibility of predicting recurrence of thyroid cancer.

• Journal of the Korean Society for information Management
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• v.41 no.1
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• pp.411-438
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• 2024

This study aims to identify and comprehensively view health information-related research trends using a bibliometric analysis. To this end, 1,193 papers from 2002 to 2023 related to "health information" were collected through the Korea Citation Index (KCI) database and analyzed in diverse aspects: research trends by period, academic fields, intellectual structure, and keyword changes. Results indicated that the number of papers related to health information continued to increase and has been decreasing since 2021. The main academic fields of health information-related research included "biomedical engineering," "preventive medicine/occupational environmental medicine," "law," "nursing," "library and information science," and "interdisciplinary research." Moreover, a co-word analysis was performed to understand the intellectual structure of research related to health information. As a result of applying the parallel nearest neighbor clustering (PNNC) algorithm to identify the structure and cluster of the derived network, four clusters and 17 subgroups belonging to them could be identified, centering on two conglomerates: "medical engineering perspective on health information" and "social science perspective on health information." An inflection point analysis was attempted to track the timing of change in the academic field and keywords, and common changes were observed between 2010 and 2011. Finally, a strategy diagram was derived through the average publication year and word frequency, and high-frequency keywords were presented by dividing them into "promising," "growth," and "mature." Unlike previous studies that mainly focused on content analysis, this study is meaningful in that it viewed the research area related to health information from an integrated perspective using various bibliometric methods.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.44 no.2
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• pp.173-182
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• 2024

In recent, there has been a trend toward primarily utilizing data-driven models employing artificial intelligence technologies, such as machine learning, for flood prediction. These data-driven models offer the advantage of utilizing pre-training results, significantly reducing the required simulation time. However, it remains that a considerable amount of flood data is necessary for the pre-training in data-driven models, while the available observed data for application is often insufficient. As an alternative, validated simulation results from physically-based models are being employed as pre-training data alongside observed data. In this context, we developed a flood mapping accelerator to generate flood maps for pre-training. The proposed accelerator automates the entire process of flood mapping, i.e., estimating flood discharge using HEC-1, calculating water surface levels using HEC-RAS, simulating channel overflow and generating flood maps using RAS Mapper. With the accelerator, users can easily prepare a database for pre-training of data-driven models from hundreds to tens of thousands of rainfall scenarios. It includes various convenient menus containing a Graphic User Interface(GUI), and its practical applicability has been validated across 26 test-beds.