• Title/Summary/Keyword: End Effect

Search Result 4,792, Processing Time 0.037 seconds

Effect of Hypothermia on the Prevention of Ventilator-Induced Lung Injury in Rats (백서에서 저체온 전처치가 환기기유발폐손상 억제에 미치는 효과)

  • Lim, Chae-Man;Hong, Sang-Bum;Koh, Youn-Suck;Shim, Tae-Sun;Lee, Sang-Do;Kim, Woo-Sung;Kim, Dong-Soon;Kim, Won-Dong
    • Tuberculosis and Respiratory Diseases
    • /
    • v.50 no.5
    • /
    • pp.540-548
    • /
    • 2001
  • Backgrounds : Because ventilator-induced lung injury is partly dependent on the intensity of vascular flow, we hypothesized that hypothermia may attenuate the degree of such an injury through a reduced cardiac output. Methods : Twenty-seven male Sprague-Dawley rats were randomly assigned to normothermia ($37{\pm}1^{\circ}C$)-injurious ventilation (NT-V) group (n=10), hypothermia ($27{\pm}1^{\circ}C$)-injurious ventilation (HT-V) group (n=10), or nonventilated control group (n=7). The two thermal groups were subjected to injurious mechanical ventilation for 20 min with peak airway pressure 30 cm $H_2O$ at zero positive end-expiratory pressure, which was translated to tidal volume $54{\pm}6\;ml$ in the NT-V group and $53{\pm}4\;ml$ in the HT-V group (p>0.05). Results : Pressure-volume (P-V) curve after the injurious ventilation was almost identical to the baseline P-V curve in the HT-V group, whereas it was shifted rightward in the NT-V group. On gross inspection, the lungs of the HT-V group appeared smaller in size, and showed less hemorrhage especially at the dependent regions, than the lungs of the NT-V group. [Wet lung weight (g)/body weight (kg)] ($1.6{\pm}0.1$ vs $2.4{\pm}1.2$ ; p=0.014) and [wet lung weight/dry lung weight] ($5.0{\pm}0.1$ vs $6.1{\pm}0.8$ ; p=0.046) of the HT-V group were both lower than those of the NT-V group, while not different from those of the control group($1.4{\pm}0.4$, $4.8{\pm}0.4$, respectively). Protein concentration of the BAL fluid of the HT-V group was lower than that of the NT-V group($1,374{\pm}726\;ug/ml$ vs $3,471{\pm}1,985\;ug/ml$;p=0.003). Lactic dehydrogenase level of the BAL fluid of the HT-V group was lower than that of the NT-V group ($0.18{\pm}0.10\;unit/ml$ vs $0.43{\pm}0.22\;unit/ml$;p=0.046). Conclusions : Hypothermia attenuated pulmonary hemorrhage, permeability pulmonary edema, and alveolar cellular injuries associated with injurious mechanical ventilation, and preserved normal P-V characteristics of the lung in rats.

  • PDF

Effects of Arbuscular Mycorrhizal Fungus, Glomus intraradices, on the Growth, Photosynthesis and Phosphorus Content of Robinia pseudoacacia Seedlings Treated with Simulated Acid Rain (Glomus 내생균근균 접종이 인공산성우를 처리한 아까시나무 묘목의 생장, 광합성, 인 함량에 미치는 영향)

  • Kim, Eun Ho;Lee, Kyung Joon;Lee, Kyu Hwa
    • Journal of Korean Society of Forest Science
    • /
    • v.95 no.6
    • /
    • pp.735-742
    • /
    • 2006
  • The objective of this study was to elucidate the tolerance of woody plants to simulated acid rain in relation to mycorrhizal inoculation. Germinating seedlings of Robinia pseudoacacia were planted in 1I pots with autoclaved soil mixture of vermiculite, sand and nursery soil at 1:1:1 ratio. Each pot was inoculated with both crushed root nodules from a wild tree of the same species and commercial arbuscular mycorrhizal inoculum of Glomus intraradices at the time of planting the seedlings. Simulated acid rains at pH 2.6, 3.6, 4.6, and 5.6 were made by mixing sulfuric acid and nitric acid at 3: 1 ratio. Each pot received nutrient solution without N and P, and was also supplied with 180 ml of the one pH level of the acid rains once a week for 50 days. The plants were grown in the green house. At the end of experimental period, plants were harvested to determine contents of chlorophyll, mineral nutrients and net photosynthesis in the tissues, dry weight of the plants, and mycorrhizal infection in the roots. Mycorrhizal infection rate was significantly reduced only at pH 2.6, which meant vitality of G intraradices was inhibited at extremely low pH. Height growth, dry weight production, nodule production and chlorophyll content were increased by mycorrhizal infection in all the pH levels except pH 3.6. Particularly, mycorrhizal inoculation increased root nodule production by 85% in pH 5.6 and 45% in 4.6 treatments. But the stimulatory effect of mycorrhizal inoculation on nodule production was reduced at pH 3.6 and 2.6. Net photosynthesis was increased by mycorrhizal infection in all the pH levels. The phosphorus(P) content in the tissues was increased by 43% in average by mycorrhizal inoculation, which was statistically significant except in pH 2.6. It was concluded that mycorrhizal inoculation of Robinia pseudoacacia would enhance growth and resistance of the plants to acid rain by improving the photosynthesis, phosphorus nutrition, and more nodule production.

Effect of Soil Moisture and Weather (atmospheric) Conditions on the Fruiting of Sarcodon aspratus in Oak Stand (토양수분과 가상인자가 참나무림내 능이의 발생에 미치는 영향)

  • Lee, Sang-Hee;Kim, Je-Su;Kim, Hong-Eun;Koo, Chang-Duck;Park, Jae-In;Shin, Chang-Sop;Shin, Won-Sop
    • Journal of Korean Society of Forest Science
    • /
    • v.94 no.6
    • /
    • pp.370-376
    • /
    • 2005
  • Sarcodon aspratus is well known as a natural edible mushroom and a symbiotic mycorrhizal fungus with oaks. This study was conducted to clarify the effects of environmental conditions on the fruiting of S. aspratus on the hillslope of Wolak Mt., Jecheon city, Chungbuk, South Korea. Soil moisture and soil temperature in S. aspratus colony were measured hourly and compared with those in the non-colony soil. The mean soil moisture during the mushroom development was 14.3% in the colony soil and 16.4% in the non-colony soil. The S. aspratus colony soils showed 2.1% less soil moisture. The mean soil temperature was $16.8^{\circ}C$ in the colony soil and $16.5^{\circ}C$ in the non-colony soil. The S. asprauts colony soils showed slightly higher temperature. It is considered that more soil water was consumed and more energy was emitted during the mycelial elongation and the mushroom development. The development of S. aspratus seems similar to that of T. matsutake which is known to be considerably affected by soil moisture, daily maximum air temperature, daily minimum air temperature and daily minimum soil temperature. The season of S. aspratus development ranges from the end of August to the beginning of October. And Ellino phenomenon and its unusual change in the weather seems to affect primodia and fruiting body development. Especially if daily minimum soil temperature continues to become higher than $20^{\circ}C$, the damage of primodia and its fruiting body was frequently observed in the field plots during the last few years recently.

Feasibility of Green Network in a Highly-dense Urbanized Area by Introducing Urban Gardens (도시정원 도입을 위한 고밀 시가화지역 내 녹지 네트워크 구축 가능성 평가)

  • Choi, Heejoon;Lee, Junga;Sohn, Heejung;Cho, Donggil;Song, Youngkeun
    • Korean Journal of Environment and Ecology
    • /
    • v.31 no.2
    • /
    • pp.252-265
    • /
    • 2017
  • This study aims to analyze the landscape ecological characteristics of green spaces within built up area of high density and evaluate the potential applicability of green patches, thereby introducing urban garden for generating green networks in residence areas. To this end, Yeoksam-Dong was selected as the site area since it is classified as both green initiative zone and alienated area of park service in Seoul. First, the current condition of green spaces in Yeoksam-Dong was identified by five categories: Street trees, private garden, public pocket garden, rooftop garden, and park. Then, the landscape index analysis through FRAGSTATS and connectivity assessment via multi-buffer zone analysis were carried out for analyzing the green networks and evaluating the potential value of green space. The results showed that the degree to which green areas in the site were distributed is arranged in the order of street tree, private garden, public pocket garden, park, and rooftop garden. In case of the street trees whose total core area (TCA, $1,618m^2$) is as high as the park's ($1,128m^2$). Private garden has potential for green network in built up area of high density by gardening since the shape of the patches are irregular (ED = 78.1m/ha) and the average distance among the patches is close (ENN=33.9m). Public pocket garden has also potential for gardening according to the result that it was found to be distributed evenly (LPI=5.7%, SHEI=0.9) with exposing external disturbance ($TCA=66m^2$). For the green network, 84% of all the study site is covered by small green network in 50m butter range of connected green area. The effect of green network was expected through gardening in public pocket garden (27%) and street tree (26%). Accordingly, it is encouraged to actively utilize street tree, private gardens, and rooftop gardens and to establish the urban gardens like local-based community gardens in public pocket garden where a variety of activities can be carried out near residential areas. By doing so, green networks can effectively be established in built up area with high density. The results of this study can contribute positively to fostering the creation of various types of urban gardens.

Control of Daily Integral PPE by the Artificial Lighting and shading screen In Greenhouse (인공광 및 차광스크린을 이용한 온실의 일일적산 광합성유효광량자속 조절)

  • 이현우
    • Journal of Bio-Environment Control
    • /
    • v.12 no.1
    • /
    • pp.45-53
    • /
    • 2003
  • The object of this study was to develop the control technology of daily integral photosynthetic photon flux (PPF) by the artificial lighting and shading screen in greenhouse. The shading time needed to get the target PPF by using two types of shading screens having shading ratio of 55% and 85% was analyzed. The results showed the shading ratio of screen to be installed in greenhouse should be different depending on the amount of target PPF to be controlled. The PPF control experiment by using the 55% shading screen in July and August showed that the maximum difference between measured and calculated value was about 5 mol$.$ $m^{-2}$ $.$ $d^{-1}$ in no shading condition. This difference is satisfactory result because the daily integral PPF is quite different depending on the weather condition. The simulation result about PPF distribution pattern shortened the time needed to find the proper arrangement of artificial lightings in greenhouse. But the further study was required to find the supplemental lighting arrangement to be able to provide the exactly uniform distribution of target light intensity. The supplemental irradiation time needed to acquire the target daily integral PPF for different supplemental light intensities, weather conditions, and months was analyzed. The result showed that the supplemental light intensity should be decided depending on the amount of target PPF to be controlled. The result of PPF control experiment conducted by using 55% shading screen and 300 $\mu$mol$.$ $m^{-2}$ $.$ $s^{-1}$ supplemental light intensity from the end of May to the beginning of June showed that the maximum difference between target and measured value was about 3 mol$.$ $d^{-1}$ $.$ $m^{-2}$ . If we consider that the difference of the daily integral PPF depending on weather condition was the maximum 30 mol$.$ $m^{-2}$ $.$ $d^{-l}$, the control effect was acceptable. Although the result of this study was the PPF control technology to grow lettuce, the data and control method obtained could be employed for other crop production.n.

Availability Assessment of Single Frequency Multi-GNSS Real Time Positioning with the RTCM-State Space Representation Parameters (RTCM-SSR 보정요소 기반 1주파 Multi-GNSS 실시간 측위의 효용성 평가)

  • Lee, Yong-Chang;Oh, Seong-Jong
    • Journal of Cadastre & Land InformatiX
    • /
    • v.50 no.1
    • /
    • pp.107-123
    • /
    • 2020
  • With stabilization of the recent multi-GNSS infrastructure, and as multi-GNSS has been proven to be effective in improving the accuracy of the positioning performance in various industrial sectors. In this study, in view that SF(Single frequency) GNSS receivers are widely used due to the low costs, evaluate effectiveness of SF Real Time Point Positioning(SF-RT-PP) based on four multi-GNSS surveying methods with RTCM-SSR correction streams in static and kinematic modes, and also derive response challenges. Results of applying SSR correction streams, CNES presented good results compared to other SSR streams in 2D coordinate. Looking at the results of the SF-RT-PP surveying using SF signals from multi-GNSS, were able to identify the common cause of large deviations in the altitude components, as well as confirm the importance of signal bias correction according to combinations of different types of satellite signals and ionospheric delay compensation algorithm using undifferenced and uncombined observations. In addition, confirmed that the improvement of the infrastructure of Multi-GNSS allows SF-RT-SPP surveying with only one of the four GNSS satellites. In particular, in the case of code-based SF-RT-SPP measurements using SF signals from GPS satellites only, the difference in the application effect between broadcast ephemeris and SSR correction for satellite orbits/clocks was small, but in the case of ionospheric delay compensation, the use of SBAS correction information provided more than twice the accuracy compared to result of the Klobuchar model. With GPS and GLONASS, both the BDS and GALILEO constellations will be fully deployed in the end of 2020, and the greater benefits from the multi-GNSS integration can be expected. Specially, If RT-ionospheric correction services reflecting regional characteristics and SSR correction information reflecting atmospheric characteristics are carried out in real-time, expected that the utilization of SF-RT-PPP survey technology by multi-GNSS and various demands will be created in various industrial sectors.

Activation of Pro-Apoptotic Multidomain Bcl-2 Family Member Bak and Mitochondria-Dependent Caspase Cascade are Involved in p-Coumaric Acid-Induced Apoptosis in Human Jurkat T Cells (p-Coumaric acid에 의해 유도되는 인체 Jurkat T 세포의 에폽토시스 기전)

  • Lee, Je-Won;Kim, Young-Ho
    • Journal of Life Science
    • /
    • v.21 no.12
    • /
    • pp.1678-1688
    • /
    • 2011
  • The apoptogenic effect of p-coumaric acid, a phenolic acid found in various edible plants, on human acute leukemia Jurkat T cells was investigated. Exposure of Jurkat T cells to p-coumaric acid (50-$150{\mu}M$) caused cytotoxicity and TdT-mediated dUTP nick-end labeling (TUNEL)-positive apoptotic DNA fragmentation along with Bak activation, ${\Delta}{\psi}m$ loss, activation of caspase-9, -3, -7, and -8, and PARP degradation in a dose-dependent manner. However,these apoptotic events were completely abrogated in Jurkat T cells overexpressing Bcl-2.Under these conditions, necrosis was not accompanied. Pretreatment of the cells with the pan-caspase inhibitor (z-VAD-fmk) could prevent p-coumaric acid-induced sub-$G_1$ peak representing apoptotic cells, whereas it failed to block ${\Delta}{\psi}m$ loss, indicating that the activation of caspase cascade was prerequisite for p-coumaric acid-induced apoptosis as a downstream event of ${\Delta}{\psi}m$ loss. FADD- and caspase-8-positive wild-type Jurkat T cell clone A3, FADD-deficient Jurkat T cell clone I2.1, and caspase-8-deficient Jurkat T cell clone I9.2 exhibited similar susceptibilities to the cytotoxicity of p-coumaric acid, excluding an involvement of Fas/FasL system in triggering the apoptosis. The apoptogenic activity of p-coumaric acid is more potent in malignant Jurkat T cells than in normal human peripheral T cells. Together, these results demonstrated that p-coumaric acid-induced apoptogenic activity in Jurkat T cellswas mediated by Bak activation, ${\Delta}{\psi}m$ loss, and subsequent activation of multiple caspases such as caspase-9, -3, -7, and-8, and PARP degradation, which could be regulated by anti-apoptotic protein Bcl-2.

Effects of Water Temperature and Estradiol-17β on the Sex Ratio and Growth of the Japanese Eel, Anguilla japonica (극동산 뱀장어, Anguilla japonica의 성비와 성장에 미치는 수온 및 estradiol-17β의 효과)

  • Kim, Dae-Jung;Lee, Nam-Sil;Kim, Shin-Kown;Lee, Bae-Ik;Seong, Ki-Baik;Kim, Kyung-Kil
    • Journal of Life Science
    • /
    • v.23 no.12
    • /
    • pp.1454-1459
    • /
    • 2013
  • This study investigated the effects that water temperature and the administration of estradiol-17${\beta}$ (E2) had on the sex ratio and growth of the Japanese eel, Anguilla japonica. Glass eels (total length${\fallingdotseq}$6.5 cm) were differentiated into an E2 group and an E2-free group and then they were reared for about four months at three water temperature levels of $20^{\circ}C$, $24^{\circ}C$, and $28^{\circ}C$. The results showed that the young eels survived normally at the rearing water temperature of ${\geq}24^{\circ}C$, and grew to a mean size of 20 cm (total length). In the E2-free group, temperature was not found to increase the sex ratio (feminizing rates); however, the sex ratio of the E2-administrated group was found to be a little higher at a high temperature ($28^{\circ}C$). The growth of the E2 group was lower than the growth of the E2-free group at $24^{\circ}C$ and the E2 concentration levels in the plasma at $24^{\circ}C$ were found to be significant after the end of the E2 administration period (178 days). Therefore, we thought that long-term administration of E2 must be considered to be the reason for growth decline in spite of the prominent sex ratio effect. Our results indicate that temperature was not related to an increase in the feminizing rate (sex ratio) in the Japanese eel, Anguilla japonica, and other environmental factors (rearing density, salinity, etc.) that have the possibility of inducing ovarian differentiation must be investigated.

A Study on Commercial Properties of Supermarket in Kwangju city (광주시 슈퍼마켓의 상업적 특성에 관한 연구)

  • Kim, Song-Mee
    • Journal of the Korean Geographical Society
    • /
    • v.31 no.1
    • /
    • pp.49-67
    • /
    • 1996
  • On of Revolutionary changes of the commercial facilities is appearance of supermarket since the 1970's. It means modernization of retail establishment size. Simultaneously, and then path of distribution resulted in change. Namely, function of wholesale and retail is mixed, path of distribution is shortened, and then distribution function become more influential. By these changes, producer, manager and consumer can be benefit. That is, a change of commercial part is accurance to change of society and economy of region. The aim of the study is to examine commercial properties of supermarket in Kwangju city, and then, it is concerned with life of residents. Factor analysis is applied to the study. The results are as follows: Four factors are abstracted. The first factor of large explanation on properties of supermarket is accounted for years of management, land lent, number of establishments of wholesale${\cdot>$retail${\cdot>$service, age of manager, distance of neighbour residence, and so on. Namely, these may be regarded as commercial environmental feature. Moreover, regional distribution on the ground of factor score is concentrated on CBD and it's neighbour area, which are the areas of highest land lent in Kwangju city. The second factor is accounted for number of supermarket and number of population in each 'dong' (smallest factor-scored area is new housing complex in an outer ring of Kwangju. The third factor is accounted for number of workers, and size of establishment. Regional distribution is concentrated on neighbour of CBD and the outer ring area. These are scattered in contrast to the first and second factors which are continuous. The fourth factor is noted on a sale price of non-foodstuffs, that is, a feature of formation of goods. The highest factor score areas are the CBD, neighbour area of the CBD and a part of an outer ring area. On the other hand, the property of supermarket is preferred to 'the near distance' according to consumer's viewpoint. Furthermore, the location of supermarket, which is actually used by residents, is almost near residental area. It means that condition of location of supermarket is important in the distance of neighbour residence. Besides, supermarkets in Kwangju city are actually situated at residental area, that is, those locations in Kwangju city correspond to preference of consumer's viewpoint. Moreover, this result corresponds to the first factor of the analysis. Namely, the distance of property of supermarket from neighbour residence has very important effect on both of consumer and manager. In the end, supermarket is strongly related to life of residents. It means that supermarket is also responsible to quality of life. On the other hand, commercial facilities have been changed according to consumer's needs and social environments. For these reasons, commercial properties of supermarket must be reexamined in according to diverse commercial facilities and change of commercial environments.

  • PDF

The Effects of Calcinated Calcium Solution Washing and Heat Treatment on the Storage Quality and Microbial Growth of Fresh-cut Broccoli (신선편이 브로콜리의 품질과 미생물 성장에 영향을 주는 소성칼슘 용액 세척 및 열처리 효과)

  • Kim, Ji Gang;Nimitkeatkai, Hataitip;Choi, Ji Woen;Lee, Sang Gyu
    • Journal of Bio-Environment Control
    • /
    • v.21 no.4
    • /
    • pp.411-418
    • /
    • 2012
  • This study was conducted to investigate the effect of calcinated calcium (CC) alone or combination with heat treatment on storage quality and microbial growth in fresh-cut broccoli. Fresh broccoli samples were cut into small pieces and washed in normal tap water (TW), $50{\mu}L{\cdot}L^{-1}$ chlorinated water (pH 6.5), $1.5g{\cdot}L^{-1}$ CC, heat treatment in TW at $45^{\circ}C$, and CC dissolved in TW at $45^{\circ}C$ for 2 minutes separately. Samples were then packaged in $50{\mu}m$ polyethylene bags and stored at $5^{\circ}C$. Results revealed that like $50{\mu}L{\cdot}L^{-1}$ chlorine, washing in CC at normal water temperature was effective in reducing microbial population in fresh-cut broccoli samples. Washing with CC combined with heat treatment increased an electrical conductivity of fresh-cut broccoli. Combined heat treatments with TW and CC reduced aerobic plate count on fresh-cut broccoli, only in initial period of storage. But, later on heat treatment induced injury of fresh-cut broccoli resulting more microbial population compared to non heat treatment. However, samples treated with CC alone had good quality with low off-odor at the end of storage. Results suggest that CC, an environment-friendly sanitizer could be an alternative to chlorinated water for washing of fresh-cut broccoli without affecting sensorial quality.