• Title/Summary/Keyword: Emulsions

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A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy (정맥 내 지질 유탁액 치료 후 성공적으로 회복한 초오 중독 1례)

  • Shin, Hee Jun;Lim, Hoon
    • Journal of The Korean Society of Clinical Toxicology
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    • v.14 no.1
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    • pp.60-65
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    • 2016
  • Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine. Among these substances, aconitine can cause fatal cardiotoxicity by activating sodium channels followed by calcium channels in myocardial cells. Even though there have been various therapeutic plans suggested comprising antidotes based on diverse case reports and studies, there is no confirmatory treatment protocol for aconite poisoning. Here, we report an aconite poisoning patient who had refractory ventricular tachyarrhythmia that did not respond to intravenous amiodarone therapies even though they were sustained for over 2 hours, but showed successful recovery following intravenous fat emulsions (IFE) therapy.

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STUDY ON THE STABILITY OF O/W AND MLV EMULSION CONTAINING DIHYDROXYACETONE

  • Joo, Yong-Joon;Han, Yeoung-Jun;Joo, Yong-Ho;Jeon, Young-Hwan
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.24 no.3
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    • pp.123-128
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    • 1998
  • Dihydroxyacetone (DHA) has been used as a self tanning agent and many emulsion formulations containing DHA have been studied. In an emulsion, many factors which have negative effect on DHP and the resultant DHA decomposition can destabilize the emulsion base. In this study, two kinds of emulsion with 5% DHA were prepared, O/W type emulsion and Multilamellavesicle (MLV) type emulsion to compare the stabilization effects of both emulsions on the DHA. The OHA concentration was analyzed quantitatively by high performance liquid Chromatography (HPLC), also the pH and viscosity of both emulsions were measured for stability. This process was carried out over 4 months. For HPLC, a bondaclone $C_{18}$ column with a mobile phase of distilled water and UV detector were used. The results of these experiment showed that DHA is more stable in an MLV emulsion than it is in an O/W type emulsion.

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Fabrication of Colloidal Clusters of Polymer Microspheres and Nonspherical Hollow Micro-particles from Pickering Emulsions

  • Cho, Young-Sang;Kim, Tae-Yeol;Yi, Gi-Ra;Kim, Young-Kuk;Choi, Chul-Jin
    • Bulletin of the Korean Chemical Society
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    • v.33 no.1
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    • pp.159-166
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    • 2012
  • We have introduced the Pickering emulsion systems to generate novel confining geometries for the selforganization of monodisperse polymer microspheres using nanoparticle-stabilized emulsion droplets encapsulating the building block particles. Then, through the slow evaporation of emulsion phases by heating, these microspheres were packed into regular polyhedral colloidal clusters covered with nanoparticle-stabilizers made of silica. Furthermore, polymer composite colloidal clusters were burnt out leaving nonspherical hollow micro-particles, in which the configurations of the cluster structure were preserved during calcination. The selfassembled porous architectures in this study will be potentially useful in various applications such as novel building block particles or supporting materials for catalysis or gas adsorption.

Droplet deformability and emulsion rheology: steady and dynamic behavior

  • Saiki Yasushi;Prestidge Clive A.
    • Korea-Australia Rheology Journal
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    • v.17 no.4
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    • pp.191-198
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    • 2005
  • The static and dynamic rheological behavior of concentrated sodium dodecylsulfate (SDS) stabilized, deformability controllable polydimethylsiloxane (PDMS) emulsions is reported and comparisons made with silica (hard sphere) suspensions. Steady-mode measurements indicate 'hard' (viscoelastic) droplets behave as hard spheres, while 'soft' (viscous) droplets induce structural flexibility of the emulsion against shear. Dynamic-mode measurements reveal that viscoelasticity of droplets provides the great magnitude of elasticity for the 'hard' emulsion, while formation of planar films between droplets is the origin of the elasticity of 'soft' emulsions. Combination of steady and dynamic rheological behavior has enabled depiction of droplet structure evolution in relation to the shear stress applied, especially by taking advantage of the normal force that reflects the transient deformation of droplets.

The Effects of HLB Value of the Surfactants Added in the Silicon Oil Emulsion Antifoamer on the Antifoaming Ability (실리콘오일 에멀젼 소포제 조성에 있어서 유화제의 HLB가 소포성능에 미치는 영향)

  • Kim, Young-Ho
    • Journal of the Korean Applied Science and Technology
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    • v.27 no.3
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    • pp.223-232
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    • 2010
  • The effects of HLB value of nonionic mixed surfactants on the stability and antifoaming ability for silicon oil type emulsions were studied. To obtain a stable silicone emulsions, a higher HLB values and higher content of surfactants were preferred. To obtain a good antifoaming ability, however, a lower HLB value (more hydrophobic) and a lower content of the surfactants were preferred. It was observed, at lower HLB values(8 or 9), that the silicone oil drops were spreaded on the foam surface and effectively reduced the surface tension. And the spreading phenomena presumably acted as an antifoaming mechanism. Therefore, a higher hydrophobicity of the silicone oil emulsion resulted in a higher ability of antifoaming action.

Effects of HLB value on oil-in-water emulsions: Droplet size, rheological behavior, zeta-potential, and creaming index

  • Hong, In Kwon;Kim, Su In;Lee, Seung Bum
    • Journal of Industrial and Engineering Chemistry
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    • v.67
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    • pp.123-131
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    • 2018
  • Using mixed nonionic surfactants Span/Tween, we investigated the effects of HLB value on the O/W emulsion stability and rheological behaviors. In this study, MS-01 (Span 60 & Tween 60) and MS-02 (Span 80 & Tween 80) was used as mixed nonionic surfactants. We considered required HLB value 10.85 and selected corresponding HLB value range 8-13. The droplet size distributions, droplet morphology, rheological properties, zeta-potential and creaming index of the emulsion samples were obtained to understand the mechanism and interaction of droplets in O/W emulsion. The results indicated that optimal HLB number for O/W emulsions was 10.8 and 10.7, while using MS-01 surfactant and MS-02 surfactant respectively. MS-01 (HLB = 10.8) sample and MS-02 (HLB = 10.7) sample showed smallest droplet size and highest zeta-potential value. Rheological properties are measured to understand rheological behaviors of emulsion samples. All emulsion samples showed no phase separation until 30 days storage time at $25^{\circ}C$.