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The Study of Radiation Reducing Method during Injection Radiopharmaceuticals (방사성의약품 투여 시 피폭선량 저감에 대한 연구)

  • Cho, Seok-Won;Jung, Seok;Park, June-Young;Oh, Shin-Hyun;NamKoong, Hyuk;Oh, Ki-Beak;Kim, Jae-Sam;Lee, Chang-Ho
    • The Korean Journal of Nuclear Medicine Technology
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    • v.16 no.1
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    • pp.80-85
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    • 2012
  • Purpose: The whole body bone scan is an examination that visualizing physiological change of bones and using bone-congenial radiopharmaceutical. The patients are intravenous injected radiopharmaceutical which labeled with radioactive isotope ($^{99m}Tc$) emitting 140 keV gammarays and scanned after injection. The 3 principles of radiation protection from external exposureare time, distance and shielding. On the 3 principles of radiation protection basis, radiopharmaceutical might just as well be injected rapidly for reducing radiation because it might be the unopened radiation source. However the radiopharmaceuticals are injected into patient directly and there is a limitation of distance control. This study confirmed the change of radiation exposure as change of distance from radiopharmaceutical and observed the change of radiation exposure afte rsetting a shelter for help to control radio-technician's exposure. Materials & methods: For calculate the average of injection time, the trained injector measured the injection time for 50 times and calculated the average (2 minutes). We made a source as filled the 99mTc-HDP 925 MBq 0.2 mL in a 1 mL syringe and measured the radiation exposure from 50 cm,100 cm,150 cm and 200 cm by using Geiger-Mueller counter (FH-40, Thermo Scientific, USA). Then we settled a lead shielding (lead equivalent 6 mm) from the source 25 cm distance and measured the radiation exposure from 50 cm distance. For verify the reproducibility, the measurement was done among 20 times. The correlation between before and after shielding was verified by using SPSS (ver. 18) as paired t-test. Results: The radiation doses according to distance during 2 minutes from the source without shielding were $1.986{\pm}0.052{\mu}$ Sv in 50 cm, $0.515{\pm}0.022{\mu}$ Sv in 100 cm, $0.251{\pm}0.012{\mu}$ Sv in 150 cm, $0.148{\pm}0.006{\mu}$ Sv in 200 cm. After setting the shielding, the radiation dose was $0.035{\pm}0.003{\mu}$ Sv. Therefore, there was a statistical significant difference between the radiation doses with shielding and without shielding ($p$<0.001). Conclusion: Because the great importance of whole body bone scan in the nuclear medicine, we should make an effort to reduce radiation exposure during radiopharmaceutical injections by referring the principles of radiation protection from external exposure. However there is a limitation of distance for direct injection and time for patients having attenuated tubules. We confirmed the reduction of radiation exposure by increasing distance. In case of setting shield from source 25 cm away, we confirmed reducing of radiation exposure. Therefore it would be better for reducing of radiation exposure to using shield during radiopharmaceutical injection.

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In the Treatment I-131, the Significance of the Research that the Patient's Discharge Dose and Treatment Ward can Affect a Patient's Kidney Function on the Significance of Various Factors (I-131 치료시 환자의 신장기능과 다양한 요인으로 의한 퇴원선량 및 치료병실 오염도의 유의성에 관한 연구)

  • Im, Kwang Seok;Choi, Hak Gi;Lee, Gi Hyun
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.1
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    • pp.62-66
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    • 2013
  • Purpose: I-131 is a radioisotope widely used for thyroid gland treatments. The physical half life is 8.01 and characterized by emitting beta and gamma rays which is used in clinical practice for the purpose of acquiring treatment and images. In order to reduce the recurrence rate after surgery in high-risk thyroid cancer patients, the remaining thyroid tissue is either removed or the I-131 is used for treatment during relapse. In cases of using a high dosage of radioactive iodine requiring hospitalization, the patient is administered dosage in the hospital isolation ward over a certain period of time preventing I-131 exposure to others. By checking the radiation amount emitted from patients before discharge, the patients are discharged after checking whether they meet the legal standards (50 uSv/h). After patients are discharged from the hospital, the contamination level is checked in many parts of the ward before the next patients are hospitalized and when necessary, decontamination operations are performed. It is expected that there is exposure to radiation when measuring the ward contamination level and dose check emitted from patients at the time of discharge whereby the radiation exposure by health workers that come from the patients in this process is the main factor. This study analyzed the correlation between discharge dose of patients and ward contamination level through a variety of factors such as renal functions, gender, age, dosage, etc.). Materials and Method: The study was conducted on 151 patients who received high-dosage radioactive iodine treatment at Soon Chun Hyang University Hospital during the period between 8/1/2011~5/31/2012 (Male: Female: 31:120, $47.5{\pm}11.9$, average dosage of $138{\pm}22.4$ mCi). As various factors expected to influence the patient discharge dose & ward contamination such as the beds, floors, bathroom floors, and washbasins, the patient renal function (GFR), age, gender, dosage, and the correlation between the expected Tg & Tg-Tb expected to reflect the remaining tissue in patients were analyzed. Results: In terms of the discharge dose and GFR, a low correlation was shown in the patient discharge dose as the GFR was higher (p < 0.0001). When comparing the group with a dosage of over 150mCi and the group with a lower dosage, the lower dosage group showed a significantly lower discharge dose ($24{\pm}10.4uSv/h$ vs $28.7{\pm}11.8uSv/h$, p<0.05). Age, gender, Tg, Tg-Tb did not show a significant relationship with discharge dose (p> 0.05). The contamination level in each spot of the treatment ward showed no significant relationship with GFR, Tg, Tg-Tb, age, gender, and dosage (p>0.05 ). Conclusion: This study says that discharge of the dose in the patient's body is low in GFR higher and Dosage 150mCi under lower. There was no case of contamination of the treatment ward, depending on the dose and renal association. This suggests that patients' lifestyles or be affected by a variety of other factors.

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Analysis of Heating Effect of an Infrared Heating System in a Small Venlo-type Glasshouse (소형 벤로형 유리온실에서 적외선등 난방 시스템의 난방효과 분석)

  • Lim, Mi Young;Ko, Chung Ho;Lee, Sang Bok;Kim, Hyo Kyeong;Bae, Yong Han;Kim, Young Bok;Yoon, Yong Cheol;Jeong, Byoung Ryong
    • FLOWER RESEARCH JOURNAL
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    • v.18 no.3
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    • pp.186-192
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    • 2010
  • An infrared heating system, installed in a small venlo-type glasshouse ($280m^2$) in Gyeongsang National University, Jinju, Korea, was used to investigate its heating effect with potted Phalaenopsis, Schefflera arboricola 'Hongkong', Ficus elastica 'Variegata', and Rosa hybrida 'Yellow King' as the test plants. Temperature changes in test plants with the system turned 'On' and 'Off' were measured by using an infrared camera and the consumption of electricity by this infrared heating system was measured and analyzed. In potted Phalaenopsis, when the set air temperature of the greenhouse was $18^{\circ}C$, temperature of leaves and the growing medium were $22.8{\sim}27^{\circ}C$ and $21.3{\sim}24.3^{\circ}C$, respectively. In such tall plants as Schefflera arboricola 'Hongkong' and Ficus elastica 'Variegata', the upper part showed the highest temperature of 24.0 and $26.9^{\circ}C$, respectively. From the results of temperature change measurements, the plant temperatures were near or above the set point temperatures with some fluctuations depending on the position or distance from the infrared heating system. When air temperature between night and dawn dropped sharply, plant temperatures were maintained close to the set temperature ($18^{\circ}C$). There was a significant difference between 'On' and 'Off' states of the infrared heating system in average temperatures of root zone and leaf: 21.8 and $17.8^{\circ}C$ with the system 'On' and 20.4 and $15.5^{\circ}C$ with the system 'Off', respectively, in a cut rose Rosa hybrida 'Yellow King'. The heating load was about $24,850{\sim}35,830kcal{\cdot}h^{-1}$, which comes to about 27,000~40,000 won in Korean currency when calculated in terms of the cost of heating by a hot water heating system heated by petroleum. The cost for heating by the infrared heating system was about 35% of that of a hot water heating system. With the infrared heating system, the air temperature during the night was maintained slightly lower than the set point air temperature, probably due to the lack of air tightness of the glasshouse. Therefore, glasshouses with an infrared heating system requires further investigation including the installation space of the heat-emitting units, temperature sensor positions, and convection.