• 오토저널
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• 제13권6호
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• pp.101-108
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• 1991

During torsional fatigue of externally cracked cylindrical specimen, crack face rubbing may occur. At this time, normal contact forces arise when shear displacements cause the crack faces to be wedged open due to mismatch of the fracture surface asperities. These normal forces, in turn, generate friction force which act in opposition to the applied shear stresses and reduce the effective stress intensity factor. The premise of the proposed work is that friction and wedging can be studied by measuring the shear and normal displacement across the crack mouth. We have measured the crack mouth compliance using the new biaxial extensometer.

• International Journal of Naval Architecture and Ocean Engineering
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• 제7권5호
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• pp.805-816
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• 2015

In the present study, external restraints imposed normal to the plate during the cooling stage were determined to be effective for reduction of the angular distortion of butt-welded or fillet-welded plate. A welding analysis model under external force during the cooling stage was idealized as a prismatic member subjected to pure bending. The external restraint was represented by vertical force on both sides of the work piece and bending stress forms in the transverse direction. The additional bending stress distribution across the plate thickness was reflected in the improved inherent strain model, and a set of inherent strain charts with different levels of bending stress were newly calculated. From an elastic linear FE analysis using the inherent strain values taken from the chart and comparing them with those from a 3D thermal elasto-plastic FE analysis, welding deformation can be calculated.

• 대한예방한의학회지
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• 제8권2호
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• pp.141-156
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• 2004

Objectives : JianTeng-Yuan(交藤圓) is said to be a prescription for preservation of health in ${\ulcorner}$HuaTuo ZhongZangJing(華陀 中藏經)${\lrcorner}$. It is known to have the effect of Bu-Shen(補腎: strengthening kidney) and Yi-Shou(益壽: prolonging the span of one's life). This study investigates whether JTY is effective on inhibition of oxidation stress. Methods : Sprague-Dawley Rats(12-week-old, weight $300{\pm}20g$) were divided into 3 groups. Normal group(n=8) was injected PBS(1ml/body, s.c) at the back neck's skin. Control group(n=8) was injected D-galactose(50mg/kg, 1ml PBS/body, s.c) to induce pathological animals. JTY group was injected the same treatment for the Control group, and fed containing JTY(10%). The whole groups were treated 1 time per day for 6 weeks. After rats were sacrificed and anti-oxidant enzyme(SOD, CAT, G-px) activity, GSH quantity of RBC and tissue(heart, liver and kidney), plasma Vit-C quantity were examined. Besides, the MDA levels of liver and kidney, lipofuscin of heart and endurance of erythrocyte membrane were measured. Results : In the JTY group, RBC's SOD activity decline was halted by 21% of the normal level, compared to the control group ; G-px activity(unit/g of Hb) increased significantly, compared to the normal group ; and the level of Vit-C in plasma increased by 16%. Heart's SOD activity was kept at the same level as that of the normal group ; and CAT activity decline was halted by 26%. Kidney's CAT and G-px activities were kept at the same level as that shown in the normal group, implying the existence of halting effect. Liver also showed a slight halting effect against the decline of anti-oxidant ability, but the effect was not significant(a=0.05). A comparison between the levels of peroxide in SD rats showed that the level of TBARS in plasma increased significantly in the control group and that it was normal in the JTY group. The livers in the JTY group, compared to those in the control group, showed 36% halting effect of the normal level while their kidney's indicated the level significantly lower than the normal level. Heart's lipofuscin increased significantly in the control group, but was alike in both the JTY and the normal groups. Endurance of erythrocyte membrane(%) decreased significantly in the control group while it was kept at the similar level in both the JTY and the normal groups, indicating the halting effect. Conclusions : This study suggests that JTY is effective to defend oxidation stress caused by D-galactose in the animals. It showed that the anti-oxidant ability was maintained and strengthened. On the other hand, it reduced the level of peroxide in animals. In sum, JTY appeared to have the equilibrium normal physiological function in SD rat.

• 대한약침학회지
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• 제18권4호
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• pp.12-19
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• 2015

Objectives: This study was done out to evaluate the effects of Sida rhombifolia methanol extract (SRM) on diabetes in moderately diabetic (MD) and severely diabetic (SD) Sprague-Dawley rats. Methods: SRM was prepared by soaking the powdered plant material in 70% methanol and rota evaporating the methanol from the extract. Effective hypoglycemic doses were established by performing oral glucose tolerance tests (OGTTs) in normal rats. Hourly effects of SRM on glucose were observed in the MD and the SD rats. Rats were grouped, five rats to a group, into normal control 1 (NC1), MD control 1 (MDC1), MD experimental 1 (MDE1), SD control 1 (SDC1), and SD experimental 1 (SDE1) groups. All rats in the control groups were administered 1 mL of distilled water (DW). The rats in the MDE1 and the SDE1 groups were administered SRM orally at 200 and 300 mg/kg body weight (BW), respectively, dissolved in 1 mL of DW. Blood was collected initially and at intervals of 1 hour for 6 hours to measure blood glucose. A similar experimental design was followed for the 30-day long-term trial. Finally, rats were sacrificed, and blood was collected to measure blood glucose, lipid profiles, thiobarbituric acid reactive substances (TBARS) and reduced glutathione (GSH). Results: OGTTs indicated that two doses (200 and 300 mg/kg BW) were effective hypoglycemic doses in normal rats. Both doses reduced glucose levels after 1 hour in the MDE1 and the SDE1 groups. A long-term trial of SRM in the MD group showed a reduced glucose level, a normal lipid profile, and normal GSH and TBARS levels. In SD rats, SRM had no statistically significant effects on these parameters. Normal weight was achieved in the MD rats, but the SD rats showed reduced BW. Conclusion: The study demonstrates that SRM has potential to alleviate the conditions of moderate diabetic, but not severe diabetes.

• 한국가스학회지
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• 제17권1호
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• pp.73-80
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• 2013

본 연구에서는 유한요소해석법을 사용하여 V홈 오링의 밀봉거동과 내구 안전성에 관련된 변형률, 응력, 접촉법선응력 해석결과를 제시하고 있다. 밀봉거동과 내구 안전성에 관한 FEM 해석결과에 의하면, V홈 형상을 갖는 오링에 작용하는 최대변형률, 최대압축응력, 최대접촉법선응력은 기존의 오링에 비해 약 1.2배나 더 높게 나타났다. 이것은 오링이 두 개의 원형을 겹치도록 형성된 중간부에 V홈을 넣었기 때문에 가능한 것으로 판단되고, V홈 오링은 볼밸브, 압력용기, 가스기기의 밀봉을 하는데 매우 유용한 것으로 알려져 있다. 그리고, V홈 오링에서 가스압력을 높여도 압출에 의한 파손현상이 발생되지 않았는데, 이것은 V홈이 형성되어 있기 때문이다. 따라서, V홈 오링은 기존 오링에 비해 밀봉수명을 연장시킬 수 있다.

• 한국융합학회논문지
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• 제10권12호
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• pp.517-523
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• 2019

본 연구는 지역사회 정신건강복지센터에 등록된 우울증환자를 대상으로 오감자극 원예요법을 제공하고 스트레스와 심박동변이에 미치는 효과를 파악하였다. 본 연구의 대상자는 C 지역 소재 1개 정신건강복지센터에 등록된 성인 우울증환자 26명(실험군=13명, 대조군=13명)이다. 실험군은 8주 1회 총 8회기의 오감자극 원예요법에 참여하였고 대조군은 프로그램 종료 후 원하는 대상자에게 원예요법을 1회 제공하였다. 수집된 자료는 서술통계, t-test, Mann-Whitney U test를 이용하여 분석하였다. 프로그램 참여 후 실험군은 대조군에 비해 지각된 스트레스(t = 3.11, p = .005)가 통계적으로 유의하게 감소하였고, 심박동변이 중 Low Frequency(t = -3.39, p = .002), Standard Deviation Normal to Normal(t = -2.48, p = .025)이 유의하게 증가하였다. 따라서 본 연구의 오감자극 원예요법이 우울증환자의 스트레스 감소에 효과가 있음이 확인되었다.

• Food Science and Biotechnology
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• 제16권6호
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• pp.967-974
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• 2007

The present work is aimed to evaluate the protective effect of glutathione-enriched Saccharomyces cerevisiae FF-8 strain on carbon tetrachloride ($CCl_4$)-induced hepatotoxicity and oxidative stress in rats. The activities of liver markers (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase), lipid peroxidative index (thiobarbituric acid-reactive substances), and the antioxidant status (reduced glutathione) were used to monitor those protective roles of FF-8 strain. The liver marker enzymes in plasma and the lipid peroxidation in the liver were increased when $CCl_4$ was treated but these were significantly decreased by FF-8 strain treatment. The hepatic concentration of glutathione in the current glutathione-enriched FF-8 strain fed animal was approximately twice as high as the normal, but this was slightly increased in response to $CCl_4$ plus glutathione-enriched FF-8 strain. The increased liver triglyceride concentration due to the $CCl_4$ treatment was significantly decreased by FF-8 strain and the reduced level reached to that of normal group. Administration of FF-8 strain in normal rat did not show any signs of harmful effects. Therefore, the current findings suggest that FF-8 strain could be an effective antioxidant with no or negligible side-effects and it might be useful for the purpose of protection treatment of hepatotoxicity and oxidative stress in $CCl_4$-treatment in rat.

• Computers and Concrete
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• 제29권2호
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• pp.81-92
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• 2022

The influence of normal stress perpendicular to the potential shear plane was always neglected in existing researches, which may lead to a serious deviation of the shear strength of concrete members in practice designs and numerical analyses. In this study, a series of experimental studies are carried out in this paper, which serves to investigate the shear behavior of concrete under compression shear loading. Based on the test results, a three-phase shear failure model for cohesive elements are developed, which is able to take into consideration the influence of normal stress on the shear strength of concrete. To identify the accuracy and applicability of the proposed model, numerical models of a double-noted concrete plate are developed and compared with experimental results. Results show that the proposed constitutive model is able to take into consideration the influence of normal stress on the shear strength of concrete materials, and is effective and accurate for describing the complex fracture of concrete, especially the failure modes under compression shear loadings.

• 한국강구조학회 논문집
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• 제18권2호
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• pp.203-211
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• 2006

본 논문에서는 집중 비틂모멘트와 등분포 비틂모멘트가 작용하는 박벽개보의 뒴구속에 대한 영향을 고려할 수 있는 새로운 유효비틀림계수를 제시한다. 상용 유한요소 프로그램의 알고리즘을 바꾸지 않고 순수 비틀림계수 대신에 제안된 비틀림계수를 직접 사용할 수 있다. 유도된 비틀림계수는 순수 비틀림과 뒴 비틀림에 의한 영향을 고려하며 순수 비틀림계수에 보정계수를 곱하여 산정한다. 순수 비틀림의 경우 유도된 계수는 순수 비틀림계수와 일치하게 나타났다. 순수 비틀림을 이용하여 본 연구에서 유도한 유효 비틀림계수는 Elhelbawey 등이 제안한 비틀림계수와 차이를 보여주고 있다. 또한, 유효 비틀림계수를 사용하여 구한 최대비틀림각을 이용하여 부재 내 에 발생하는 전단응력과 다른 연구자의 결과들과 비교, 검토한다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 추계학술대회
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• pp.220-225
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• 2004

The mesh-insensitive structural stress procedure by Dong is modified to apply to the welded joints with local thickness variation and inignorable shear/normal stresses along local discontinuity surface. In order to make use of the structural stress based K solution for fatigue correlation of welded joints, a proper crack growth model needs to be developed. There exist some significant discrepancies in inferring the slope or crack growth exponent in the conventional Paris law regime. Two-stage crack growth model was not considered since its applications are focused upon the fatigue behavior in welded joints in which the load ratio effects are considered negligible. In this paper, a two-stage crack growth law considering high mean loading is proposed and proven to be effective in unifying the so-called anomalous short crack growth data.