• Title/Summary/Keyword: Effective Flow Area

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Evaluation of GIS-based Landslide Hazard Mapping (GIS 기반 산사태 예측모형의 적용성 평가)

  • Oh, Kyoung-Doo;Hong, Il-Pyo;Jun, Byong-Ho;Ahn, Won-Sik;Lee, Mee-Young
    • Journal of Korea Water Resources Association
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    • v.39 no.1 s.162
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    • pp.23-33
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    • 2006
  • In this study, application potential of SINMAP, a GIS-based landslide hazard mapping tool, is evaluated through a case study. Through the application to the severe landslide events occurred during a heavy storm in 1991 on the Mt. Dalbong area about 78 kilometers south from Seoul, SINMAP successfully spotted most landslide sites. The effects and proper ranges of three calibration parameters of SINMAP, i.e. the soil internal friction angle, the combined cohesion of tree roots and soil, and T/R, were examined through comparison of predicted landslides with the landslide inventory data. From the findings of this study, it seems that SINMAP could be used as an effective screening tool for landslide hazard mapping especially for mountain areas with fairly steep slopes and relatively thin soil layers.

A Novel Anti-Microbial Peptide from Pseudomonas, REDLK Induced Growth Inhibition of Leishmania tarentolae Promastigote in Vitro

  • Yu, Yanhui;Zhao, Panpan;Cao, Lili;Gong, Pengtao;Yuan, Shuxian;Yao, Xinhua;Guo, Yanbing;Dong, Hang;Jiang, Weina
    • Parasites, Hosts and Diseases
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    • v.58 no.2
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    • pp.173-179
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    • 2020
  • Leishmaniasis is a prevalent cause of death and animal morbidity in underdeveloped countries of endemic area. However, there is few vaccine and effective drugs. Antimicrobial peptides are involved in the innate immune response in many organisms and are being developed as novel drugs against parasitic infections. In the present study, we synthesized a 5-amino acid peptide REDLK, which mutated the C-terminus of Pseudomonas exotoxin, to identify its effect on the Leishmania tarentolae. Promastigotes were incubated with different concentration of REDLK peptide, and the viability of parasite was assessed using MTT and Trypan blue dye. Morphologic damage of Leishmania was analyzed by light and electron microscopy. Cellular apoptosis was observed using the annexin V-FITC/PI apoptosis detection kit, mitochondrial membrane potential assay kit and flow cytometry. Our results showed that Leishmania tarentolae was susceptible to REDLK in a dose-dependent manner, disrupt the surface membrane integrity and caused parasite apoptosis. In our study, we demonstrated the leishmanicidal activity of an antimicrobial peptide REDLK from Pseudomonas aeruginosa against Leishmania tarentolae in vitro and present a foundation for further research of anti-leishmanial drugs.

Effective Simulation Technology for Near Shore Current Flow (연안해수유동에 관한 효율적인 수치계산기법)

  • Yoon, B.S.;Rho, J.H.;Fujino, M.;Hamada, T.
    • Journal of the Society of Naval Architects of Korea
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    • v.32 no.4
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    • pp.38-47
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    • 1995
  • The three-dimensional multi-layer computer simulation technology for tidal current developed in the previous study is updated to a new version. many improvements are achieved by following changes : (1) No-reflection condition is adopted instead of no-gradient condition as an open boundary condition. (2) Time marching algorithm is changed so that velocity and pressure(surface movement) might be salved in turn at different time step (3) Convection term in equation of motion is estimated by upwind differencing scheme instead of central differencing. The stability is improved considerably and the steady state is achieved within 2 tidal periods which is about 3 times shorter than that of the old version. Moreover, fluctuations in time disappeared by introducing the new time marching technique. An application to the real near shore area(near Inchon harbor) is performed by the new version. Simulated results are compared with those by the simulation total developed in the University of Tokyo. Validity and effectiveness of the two simulation technologies are chocked through the comparative research works.

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Adaptive V1-MT model for motion perception

  • Li, Shuai;Fan, Xiaoguang;Xu, Yuelei;Huang, Jinke
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.1
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    • pp.371-384
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    • 2019
  • Motion perception has been tremendously improved in neuroscience and computer vision. The baseline motion perception model is mediated by the dorsal visual pathway involving the cortex areas the primary visual cortex (V1) and the middle temporal (V5 or MT) visual area. However, few works have been done on the extension of neural models to improve the efficacy and robustness of motion perception of real sequences. To overcome shortcomings in situations, such as varying illumination and large displacement, an adaptive V1-MT motion perception (Ad-V1MTMP) algorithm enriched to deal with real sequences is proposed and analyzed. First, the total variation semi-norm model based on Gabor functions (TV-Gabor) for structure-texture decomposition is performed to manage the illumination and color changes. And then, we study the impact of image local context, which is processed in extra-striate visual areas II (V2), on spatial motion integration by MT neurons, and propose a V1-V2 method to extract the image contrast information at a given location. Furthermore, we take feedback inputs from V2 into account during the polling stage. To use the algorithm on natural scenes, finally, multi-scale approach has been used to handle the frequency range, and adaptive pyramidal decomposition and decomposed spatio-temporal filters have been used to diminish computational cost. Theoretical analysis and experimental results suggest the new Ad-V1MTMP algorithm which mimics human primary motion pathway has universal, effective and robust performance.

Enhancement of Cu Wire Bondability by Increasing the Surface Roughness of Capillary (표면 요철이 발달된 캐필러리 적용에 따른 Cu 와이어의 본딩 특성)

  • Lee, Jong-Hyun;Kim, Ju-Hyung;Kang, Hong-Jeon;Kim, Hak-Bum;Moon, Jung-Tak;Riu, Doh-Hyung
    • Korean Journal of Metals and Materials
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    • v.50 no.12
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    • pp.913-920
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    • 2012
  • In spite of some problems in processability and bondability, Au wires in the microelectronics industry are gradually being replaced by copper wires to reduce the cost of raw material. In this article, the effects of surface roughness enhanced capillaries on thermosonic Cu wire bonding were evaluated. The roughness-enhanced zirconia toughened alumina (ZTA) capillaries were fabricated via a thermal grooving technique. As a result, the shear bond strength of first bonds (ball bonds) bonded using the roughness-enhanced capillary was enhanced by 15% as compared with that of normal bonds due to more effective plastic deformation and flow of a Cu ball. In the pull-out test of second bonds (stitch bonds), processed at two limit conditions on combinations of process parameters, the bond strength of bonds formed using the roughness-enhanced capillary also resulted in values higher by 55.5% than that of normal bonds because of the increase in the bonding area, indicating the expansion of a processing window for Cu wire bonding. These results suggest that the adoption of roughness-enhanced capillaries is a promising approach for enhancing processability and bondability in Cu wire bonding.

Experimental Study on the Setting Time and Compressive Strength of Nano-Micro Pozzolanic Binders as Cement Composites (포졸란 혼화재의 입자 크기 및 비표면적에 따른 응결시간 발현 및 압축강도 특성 평가)

  • Kim, Won-Woo;Yang, Keun-Hyeok
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.10 no.3
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    • pp.269-275
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    • 2022
  • In this study, the setting time and compressive strength of cement paste composites applied with nano-micro pozzolanic binders were experimental analyzed. The pozzolanic binder was reduced initial and final setting time and the compressive strength was increased. Micro silica was effective in decrease the initial setting and final setting time and impressing the compressive strength. When two or more cement binders were used, the using of silica fume and a small amount of nano silica at reduced the setting time to 62-64 % to OPC cement and the compressive strength was increased to 117 %. A small amount of mixing the nano silica was effect to pore filling and pozzolanic activation. However, the addition of a chemical admixture should be considered when mixing table design because pozzolanic binders high specific surface area causes a decrease in cement composites flow.

Treatment of Facial Arteriovenous Malformations by Embolization: A Case Report (색전술에 의한 안면부 동정맥 기형의 치료 : 증례 보고)

  • Jeongyeon, Kim;Hyunsoo, Lim;Okhyung, Nam;Hyo-seol, Lee;Sungchul, Choi;Misun, Kim
    • Journal of the korean academy of Pediatric Dentistry
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    • v.49 no.2
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    • pp.228-233
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    • 2022
  • Arteriovenous malformations (AVMs) are rare congenital anomalies characterized by direct communication between arteries and veins that bypass the capillary bed. AVMs may not manifest clinically until late infancy or childhood. In particular, facial AVMs can cause urgent life-threatening dental events. A 5-year-old girl without a medical history visited the hospital because of spontaneous gingival bleeding around the posterior gingival area of the lower left 2nd primary molar. Angiography through the femoral approach under general anesthesia was performed for differential diagnosis and therapeutic option. The blood flow was effectively reduced after arterial embolization alone, and there was no evidence of recurrence at the 5-month follow-up. The present study reports that embolization of the affected vessels can be a more effective and safe method than surgical resection for the treatment of AVM during the growth period.

Design Factor Analysis of Aerospike Pintle Nozzle for Increasing Thrust in Off-Design (탈설계 조건에서 추력 증대를 위한 에어로 스파이크 핀틀 노즐의 설계인자 분석 연구)

  • Kim, Jeongjin
    • Journal of Aerospace System Engineering
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    • v.16 no.4
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    • pp.1-9
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    • 2022
  • A design factor analysis was conducted to reduce the thrust reduction in the off-design, due to the driving of the aerospike pintle nozzle. The close (NPR 100) as well as the open (NPR 11) stroke were fixed, as under-expansion conditions. The pintle contour, pintle head radius (R), cowl angle (θ), and cowl exit length (L) were selected as design factors. The change in thrust was analyzed, using a verified numerical analysis technique. First, the pintle head radius and the length of the cowl exit had little influence on the thrust. The cowl angle changed the mass flow rate by affecting the effective nozzle throat area, and created a reverse pressure gradient at the cowl exit. As a result of applying the dual aerospike contour, it was confirmed that the thrust in the design-off increased by approximately 1.2%, compared to the reference case and by approximately 3.4% compared to the worst case.

The efficacy of different implant surface decontamination methods using spectrophotometric analysis: an in vitro study

  • Roberto Giffi;Davide Pietropaoli;Leonardo Mancini;Francesco Tarallo;Philipp Sahrmann;Enrico Marchetti
    • Journal of Periodontal and Implant Science
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    • v.53 no.4
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    • pp.295-305
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    • 2023
  • Purpose: Various methods have been proposed to achieve the nearly complete decontamination of the surface of implants affected by peri-implantitis. We investigated the in vitro debridement efficiency of multiple decontamination methods (Gracey curettes [GC], glycine air-polishing [G-Air], erythritol air-polishing [E-Air] and titanium brushes [TiB]) using a novel spectrophotometric ink-model in 3 different bone defect settings (30°, 60°, and 90°). Methods: Forty-five dental implants were stained with indelible ink and mounted in resin models, which simulated standardised peri-implantitis defects with different bone defect angulations (30°, 60°, and 90°). After each run of instrumentation, the implants were removed from the resin model, and the ink was dissolved in ethanol (97%). A spectrophotometric analysis was performed to detect colour remnants in order to measure the cumulative uncleaned surface area of the implants. Scanning electron microscopy images were taken to assess micromorphological surface changes. Results: Generally, the 60° bone defects were the easiest to debride, and the 30° defects were the most difficult (ink absorption peak: 0.26±0.04 for 60° defects; 0.32±0.06 for 30° defects; 0.27±0.04 for 90° defects). The most effective debridement method was TiB, independently of the bone defect type (TiB vs. GC: P<0.0001; TiB vs. G-Air: P=0.0017; TiB vs. GE-Air: P=0.0007). GE-Air appeared to be the least efficient method for biofilm debridement. Conclusions: T-brushes seem to be a promising decontamination method compared to the other techniques, whereas G-Air was less aggressive on the implant surface. The use of a spectrophotometric model was shown to be a novel but promising assessment method for in vitro ink studies.

Shear lag effect of varied sectional cantilever box girder with multiple cells

  • Guo, Zengwei;Liu, Xinliang;Li, Longjing
    • Structural Engineering and Mechanics
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    • v.84 no.3
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    • pp.295-310
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    • 2022
  • This paper proposes a modified bar simulation method for analyzing the shear lag effect of variable sectional box girder with multiple cells. This theoretical method formulates the equivalent area of stiffening bars and the allocation proportion of shear flows in webs, and re-derives the governing differential equations of bar simulation method. The feasibility of the proposed method is verified by the model test and finite element (FE) analysis of a simply supported multi-cell box girder with constant depth. Subsequently, parametric analysis is conducted to explore the mechanism of shear lag effect of varied sectional cantilever box girder with multiple cells. Results show that the shear lag behavior of variable box-section cantilever box girder is weaker than that of box girder with constant section. It is recommended to make the gradient of shear flow in the web with respect to span length vary as smoothly as possible for eliminating the shear lag effect of box girder. An effective countermeasure for diminishing shear lag effect is to increase the number of box chambers or change the variation manner of bridge depth. The shear lag effect of varied sectional cantilever box girder will get more server when the length of central flanges is shorter than 0.26 or longer than 0.36 times of total width of top flange, as well as the cantilever length exceeds 0.29 times of total length of box's flange. Therefore, the distance between central webs can adjust the shear lag effect of box girder. Especially, the width ratio of cantilever plate with respect to total length of top flange is proposed to be no more 1/3.